INTEDE - Interactome of Drug-Metabolizing Enzyme Database Title - Sequence (FASTA format) and structure (PDB file) data of DMEs Version 1.8.1 (2020.08.15) Provided by IDRB Lab of Innovative Drug Reasearch and Bioinformatics College of Pharmaceutical Sciences Zhejiang University https://idrblab.org/ Any question about data provided here, please contact with: Dr. Yin (yinjiayi@zju.edu.cn) and Dr. Li (lifengcheng@zju.edu.cn) -------------------------------------------------------------------------------------------------------- > DME ID: DME0001 DME Name: Cytochrome P450 3A4 (CYP3A4) PDB ID: 1W0F; 1W0G; 2J0D; 2V0M; 3NXU; 3TJS; 3UA1; 4D6Z; 4D75 MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMF DMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYS MDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICV FPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSI IFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVV NETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLG GLLQPEKPVVLKVESRDGTVSGA > DME ID: DME0002 DME Name: Aromatase (CYP19A1) PDB ID: 3S79; 3S7S; 4GL5; 4GL7; 4KQ8; 5JKV; 5JKW; 5JL6; 5JL7 MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLI SHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKL GLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTN ESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWL YKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCI LEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFI YESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAK NVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLH PDETKNMLEMIFTPRNSDRCLEH > DME ID: DME0003 DME Name: Cytochrome P450 1A2 (CYP1A2) PDB ID: 2HI4 MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKN PHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDG QSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELM AGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFP ILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGN LIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLS DRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPEL WEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLE FSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN > DME ID: DME0004 DME Name: UDP-glucuronosyltransferase 1A1 (UGT1A1) PDB ID: Not Available MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVL APDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDS AMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLE FEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQR EVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEH GIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDL LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTS EDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHD LTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0005 DME Name: Cytochrome P450 2A6 (CYP2A6) PDB ID: 2FDU; 2FDV; 2FDW; 2FDY; 3EBS; 3T3Q; 3T3R; 4EJJ; 4RUI MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK ISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSN GERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSN VISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQL LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFI GGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQ RFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEK GQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGF ATIPRNYTMSFLPR > DME ID: DME0006 DME Name: Cytochrome P450 1A1 (CYP1A1) PDB ID: 4I8V; 6DWM; 6DWN MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPH LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQS MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAG PGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPIL RYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANV QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS DRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKL WVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEF SVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS > DME ID: DME0007 DME Name: RNA cytidine acetyltransferase (hALP) PDB ID: Not Available MHRKKVDNRIRILIENGVAERQRSLFVVVGDRGKDQVVILHHMLSKATVKARPSVLWCYK KELGFSSHRKKRMRQLQKKIKNGTLNIKQDDPFELFIAATNIRYCYYNETHKILGNTFGM CVLQDFEALTPNLLARTVETVEGGGLVVILLRTMNSLKQLYTVTMDVHSRYRTEAHQDVV GRFNERFILSLASCKKCLVIDDQLNILPISSHVATMEALPPQTPDESLGPSDLELRELKE SLQDTQPVGVLVDCCKTLDQAKAVLKFIEGISEKTLRSTVALTAARGRGKSAALGLAIAG AVAFGYSNIFVTSPSPDNLHTLFEFVFKGFDALQYQEHLDYEIIQSLNPEFNKAVIRVNV FREHRQTIQYIHPADAVKLGQAELVVIDEAAAIPLPLVKSLLGPYLVFMASTINGYEGTG RSLSLKLIQQLRQQSAQSQVSTTAENKTTTTARLASARTLYEVSLQESIRYAPGDAVEKW LNDLLCLDCLNITRIVSGCPLPEACELYYVNRDTLFCYHKASEVFLQRLMALYVASHYKN SPNDLQMLSDAPAHHLFCLLPPVPPTQNALPEVLAVIQVCLEGEISRQSILNSLSRGKKA SGDLIPWTVSEQFQDPDFGGLSGGRVVRIAVHPDYQGMGYGSRALQLLQMYYEGRFPCLE EKVLETPQEIHTVSSEAVSLLEEVITPRKDLPPLLLKLNERPAERLDYLGVSYGLTPRLL KFWKRAGFVPVYLRQTPNDLTGEHSCIMLKTLTDEDEADQGGWLAAFWKDFRRRFLALLS YQFSTFSPSLALNIIQNRNMGKPAQPALSREELEALFLPYDLKRLEMYSRNMVDYHLIMD MIPAISRIYFLNQLGDLALSAAQSALLLGIGLQHKSVDQLEKEIELPSGQLMGLFNRIIR KVVKLFNEVQEKAIEEQMVAAKDVVMEPTMKTLSDDLDEAAKEFQEKHKKEVGKLKSMDL SEYIIRGDDEEWNEVLNKAGPNASIISLKSDKKRKLEAKQEPKQSKKLKNRETKNKKDMK LKRKK > DME ID: DME0008 DME Name: Sulfotransferase 1A1 (SULT1A1) PDB ID: 2D06; 3QVU; 3QVV; 3U3J; 3U3K; 3U3M; 3U3O; 3U3R; 4GRA MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL > DME ID: DME0009 DME Name: Cytochrome P450 2D6 (CYP2D6) PDB ID: 3TBG; 3TDA; 4WNT; 4WNU; 4WNV; 4WNW; 4XRY; 4XRZ; 5TFT MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQ LRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVF LARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKV LRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVA DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVI HEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV FAFLVSPSPYELCAVPR > DME ID: DME0010 DME Name: Cytochrome P450 4B1 (CYP4B1) PDB ID: Not Available MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE IQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQ WIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDI FCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT PHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKL SDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDL GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWP DPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDP SRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK > DME ID: DME0011 DME Name: Glutathione S-transferase alpha-1 (GSTA1) PDB ID: 1GSF; 1GUH; 1K3L; 1K3O; 1K3Y; 1LBK; 1PKW; 1PKZ; 1PL1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF > DME ID: DME0012 DME Name: Cytochrome P450 3A5 (CYP3A5) PDB ID: 5VEU MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKF DTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISL AEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYS MDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSL FPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSI IFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVV NETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFS KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG LLQPEKPIVLKVDSRDGTLSGE > DME ID: DME0013 DME Name: Cytochrome P450 2E1 (CYP2E1) PDB ID: 3E4E; 3E6I; 3GPH; 3KOH; 3LC4; 3T3Z MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGP TWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVI ADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVA EVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAG TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRF ITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGK FKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGC IPPRYKLCVIPRS > DME ID: DME0014 DME Name: Thiopurine methyltransferase (TPMT) PDB ID: 2BZG; 2H11 MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGK SGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKV FKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQY LLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRCLEKVDAFEERHKSWGIDCLFEKLY LLTEK > DME ID: DME0015 DME Name: Cytochrome P450 3A7 (CYP3A7) PDB ID: Not Available MDLIPNLAVETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGNALSFRKGYWTF DMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISI AEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYS MDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNITV FPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSI IFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVV NETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFS KKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFG GLLLTEKPIVLKAESRDETVSGA > DME ID: DME0016 DME Name: Cytochrome P450 2F1 (CYP2F1) PDB ID: Not Available MDSISTAILLLLLALVCLLLTLSSRDKGKLPPGPRPLSILGNLLLLCSQDMLTSLTKLSK EYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDR WKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIIC SVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGELYDIFPSLLDWVPGPHQRIFQNFKC LRDLIAHSVHDHQASLDPRSPRDFIQCFLTKMAEEKEDPLSHFHMDTLLMTTHNLLFGGT KTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQRFA DIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSF KKSPAFMPFSAGRRLCLGESLARMELFLYLTAILQSFSLQPLGAPEDIDLTPLSSGLGNL PRPFQLCLRPR > DME ID: DME0017 DME Name: Cytochrome P450 2C18 (CYP2C18) PDB ID: 2CIK; 2H6P MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKSLTNFSKV YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICS VIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLPGSHNKIAENFAYI KSYVLERIKEHQESLDMNSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTE TTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYID LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK KSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDIDITPIANAFGRVP PLYQLCFIPV > DME ID: DME0018 DME Name: Cytochrome P450 2C8 (CYP2C8) PDB ID: 1PQ2; 2NNH; 2NNI; 2NNJ; 2VN0 MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKV YGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRW KEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICS VVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALT RSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTE TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLP PSYQICFIPV > DME ID: DME0019 DME Name: Cytochrome P450 2C9 (CYP2C9) PDB ID: 1R9O; 4NZ2; 5A5I; 5A5J; 5K7K; 5W0C; 5X23; 5X24; 5XXI MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKV YGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKW KEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICS IIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFM KSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTE TTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYID LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK KSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVP PFYQLCFIPV > DME ID: DME0020 DME Name: Cytochrome P450 2B6 (CYP2B6) PDB ID: 3QU8; 3UA5; 4I91; 4RQL; 4RRT; 4ZV8; 5UAP; 5UDA; 5UEC MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFRE KYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNR WKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIIC SIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVYKNLQE INAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGT ETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFS DLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGAL KKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKI PPTYQIRFLPR > DME ID: DME0021 DME Name: Mephenytoin 4-hydroxylase (CYP2C19) PDB ID: 4GQS MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKI YGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRW KEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICS IIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFM ESDILEKVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTE TTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYID LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK KSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVP PFYQLCFIPV > DME ID: DME0022 DME Name: Cytochrome P450 3A43 (CYP3A43) PDB ID: Not Available MDLIPNFAMETWVLVATSLVLLYIYGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNF DRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSF AEDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYT MDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGL FPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSI IIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVV NETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFS KKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNL PILQPEKPIVLKVHLRDGITSGP > DME ID: DME0023 DME Name: Cytochrome P450 1B1 (CYP1B1) PDB ID: 3PM0; 6IQ5 MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRRRQLRSAPPGPFAWPLI GNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPAF ASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVAL LVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSL VDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSA EKKAAGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAEL DQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVV FVNQWSVNHDPLKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQL FLFISILAHQCDFRANPNEPAKMNFSYGLTIKPKSFKVNVTLRESMELLDSAVQNLQAKE TCQ > DME ID: DME0024 DME Name: Steroid 17-alpha-monooxygenase (CYP17A1) PDB ID: 3SWZ; 4NKV; 4NKW; 4NKX; 4NKY; 4NKZ; 5IRQ; 5IRV; 5UYS MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKY GPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAH WQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVIS LICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRN DLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIF GAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREV LRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNP AGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIP KVVFLIDSFKVKIKVRQAWREAQAEGST > DME ID: DME0025 DME Name: Cytochrome P450 4F2 (CYP4F2) PDB ID: Not Available MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS > DME ID: DME0026 DME Name: Vitamin D(3) 25-hydroxylase (CYP27A1) PDB ID: 1MFX MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAPGAGPGVRRRQRSLEEI PRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAPLLEQVMRQ EGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLKPAEAALYTDAFNE VIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTF VRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAA GPDGIQVSGYLHFLLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEA LHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPK NTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRR IAELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQRQC > DME ID: DME0027 DME Name: Steroid 11-beta-hydroxylase (CYP11B1) PDB ID: 6M7X MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQG YEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR QHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNA RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM PRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS PDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATT ELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRP ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQED IKMVYSFILRPSMFPLLTFRAIN > DME ID: DME0028 DME Name: Cholesterol 24-hydroxylase (CYP46A1) PDB ID: 2Q9F; 2Q9G; 3MDM; 3MDR; 3MDT; 3MDV; 4ENH; 4FIA; 4J14 MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPCFWKKDEVGGRVL QDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERL FGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSM QDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQL REVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVTFF IAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKES LRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGA PKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKPLD PVLCTLRPRGWQPAPPPPPC > DME ID: DME0029 DME Name: Lauric acid omega-hydroxylase (CYP4A11) PDB ID: Not Available MSVSVLSPSRLLGDVSGILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLF GHIQELQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGSY RFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQD SPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQND TIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKM ENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGAS ITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHH NPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFEL LPDPTRIPIPIARLVLKSKNGIHLRLRRLPNPCEDKDQL > DME ID: DME0030 DME Name: Cytochrome P450 2A13 (CYP2A13) PDB ID: 2P85; 2PG5; 2PG6; 2PG7; 3T3S; 4EJG; 4EJH; 4EJI MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK ISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSN GERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSN VISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKE LQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFF AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKK GQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDIDVSPKHVGF ATIPRNYTMSFLPR > DME ID: DME0031 DME Name: Cytochrome P450 2J2 (CYP2J2) PDB ID: Not Available MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVD FEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHI FKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDP HFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFL PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN LICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMP YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT FNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLS LKFRMGITISPVSHRLCAVPQV > DME ID: DME0032 DME Name: Retinoic acid 4-hydroxylase 26B1 (CYP26B1) PDB ID: Not Available MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIG ETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRS TRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAIN VYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQAR QILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYAT TASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKE VMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQA RSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVL HPVDGLSVKFFGLDSNQNEILPETEAMLSATV > DME ID: DME0033 DME Name: Cytochrome P450 2S1 (CYP2S1) PDB ID: Not Available MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMRL SKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSN GERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSN VVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHH VSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLL FAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEA QRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDA DGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLSLKPTVSG LFNIPPAFQLQVRPTDLHSTTQTR > DME ID: DME0034 DME Name: Leukotriene B4 omega-hydroxylase (CYP4F3) PDB ID: Not Available MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS > DME ID: DME0036 DME Name: Aldosterone synthase (CYP11B2) PDB ID: 4DVQ; 4FDH; 4ZGX MALRAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQG YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYR QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNA RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM PRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELS LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRP ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQED IKMVYSFILRPGTSPLLTFRAIN > DME ID: DME0037 DME Name: Steroid 21-hydroxylase (CYP21A2) PDB ID: 2GEG; 4Y8W MLLLGLLLLPLLAGARLLWNWWKLRSLHLPPLAPGFLHLLQPDLPIYLLGLTQKFGPIYR LHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLSLGDYSLLWKAHK KLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDK IKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQ LRQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTL SWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVP LALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRALA FGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQPFQVRL QPRGMGAHSPGQNQ > DME ID: DME0038 DME Name: Vitamin D(3) 24-hydroxylase (CYP24A1) PDB ID: Not Available MSSPISKSRSLAAFLQQLRSPRQPPRLVTSTAYTSPQPREVPVCPLTAGGETQNAAALPG PTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEALYR TESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKLDNKIN EVLADFMGRIDELCDERGHVEDLYSELNKWSFESICLVLYEKRFGLLQKNAGDEAVNFIM AIKTMMSTFGRMMVTPVELHKSLNTKVWQDHTLAWDTIFKSVKACIDNRLEKYSQQPSAD FLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL PENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQ VLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIV RKYDIQATDNEPVEMLHSGTLVPSRELPIAFCQR > DME ID: DME0039 DME Name: Dimethylaniline oxidase 3 (FMO3) PDB ID: Not Available MGKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFS NSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFA TTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPG VFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFG TFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVK PNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPPL LEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEKKRKWF GKSETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQWP GARNAILTQWDRSLKPMQTRVVGRLQKPCFFFHWLKLFAIPILLIAVFLVLT > DME ID: DME0040 DME Name: UDP-glucuronosyltransferase 2B7 (UGT2B7) PDB ID: 2O6L MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSA SILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFG DITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTF EKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVL GRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSG ENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQN DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTM SSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAA HDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND > DME ID: DME0041 DME Name: UDP-glucuronosyltransferase 1A3 (UGT1A3) PDB ID: Not Available MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVV LTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNM SLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDL DFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQ REVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGE HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0042 DME Name: UDP-glucuronosyltransferase 1A9 (UGT1A9) PDB ID: Not Available MACTGWTSPLPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVVVVMP EVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSIYSLLMGSYNDIFDLF FSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCHYLEEG AQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEILQTPVT EYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIV VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0043 DME Name: Catechol O-methyltransferase (COMT) PDB ID: 3BWY; 4PYI; 4PYJ; 4PYK; 4XUC; 4XUD; 4XUE; 5LSA; 6I3C MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRIL NHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCG YSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKY DVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFE CTHYQSFLEYREVVDGLEKAIYKGPGSEAGP > DME ID: DME0044 DME Name: Monoamine oxidase type A (MAO-A) PDB ID: 1H8Q; 2BXR; 2BXS; 2Z5X; 2Z5Y MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS > DME ID: DME0045 DME Name: Monoamine oxidase type B (MAO-B) PDB ID: 1OJ9; 1OJA; 1OJC; 1OJD; 1S2Q; 1S2Y; 1S3B; 1S3E; 2BK3 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV > DME ID: DME0046 DME Name: Calcidiol 1-monooxygenase (CYP27B1) PDB ID: Not Available MTQTLKYASRVFHRVRWAPELGASLGYREYHSARRSLADIPGPSTPSFLAELFCKGGLSR LHELQVQGAAHFGPVWLASFGTVRTVYVAAPALVEELLRQEGPRPERCSFSPWTEHRRCR QRACGLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPP ALVRDVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPH WLRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFRE ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPA QFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP EPGAAPVRPKTRTVLVPERSINLQFLDR > DME ID: DME0047 DME Name: UDP-glucuronosyltransferase 2B4 (UGT2B4) PDB ID: Not Available MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSA SISFDPNSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMWTFN DILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAI EKHSGGLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVL GRPTTLSETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLHCKPAKPLPKEMEEFVQSSG ENGVVVFSLGSMVSNTSEERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRLYKWIPQN DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTM SSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAA HDLTWFQYHSLDVTGFLLACVATVIFIITKCLFCVWKFVRTGKKGKRD > DME ID: DME0048 DME Name: UDP-glucuronosyltransferase 1A4 (UGT1A4) PDB ID: Not Available MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0049 DME Name: UDP-glucuronosyltransferase 2B15 (UGT2B15) PDB ID: Not Available MSLKWTSVFLLIQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVTVLTSSA STLVNASKSSAIKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEY YDYSNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGELLAELFNIPFLYSLRFSVGYT FEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEV LGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSS GENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQ NDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRT MSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVA AHNLTWIQYHSLDVIAFLLACVATVIFIITKFCLFCFRKLAKKGKKKKRD > DME ID: DME0050 DME Name: N-acetyltransferase 1 (NAT1) PDB ID: 2DSS; 2GWU; 2IJA; 2PQT MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYI VDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDL LEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT HRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI > DME ID: DME0051 DME Name: N-acetyltransferase 2 (NAT2) PDB ID: 2PFR MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIV RRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYI VDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHL LPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILT YRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI > DME ID: DME0052 DME Name: Aldehyde oxidase (AOX1) PDB ID: 4UHW; 4UHX; 5EPG; 6Q6Q MDRASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYN PITKRIRHHPANACLIPICSLYGAAVTTVEGIGSTHTRIHPVQERIAKCHGTQCGFCTPG MVMSIYTLLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFCKTSGCCQSKENGVCC LDQGINGLPEFEEGSKTSPKLFAEEEFLPLDPTQELIFPPELMIMAEKQSQRTRVFGSER MMWFSPVTLKELLEFKFKYPQAPVIMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHA YNGLTLGAGLSLAQVKDILADVVQKLPEEKTQMYHALLKHLGTLAGSQIRNMASLGGHII SRHPDSDLNPILAVGNCTLNLLSKEGKRQIPLNEQFLSKCPNADLKPQEILVSVNIPYSR KWEFVSAFRQAQRQENALAIVNSGMRVFFGEGDGIIRELCISYGGVGPATICAKNSCQKL IGRHWNEQMLDIACRLILNEVSLLGSAPGGKVEFKRTLIISFLFKFYLEVSQILKKMDPV HYPSLADKYESALEDLHSKHHCSTLKYQNIGPKQHPEDPIGHPIMHLSGVKHATGEAIYC DDMPLVDQELFLTFVTSSRAHAKIVSIDLSEALSMPGVVDIMTAEHLSDVNSFCFFTEAE KFLATDKVFCVGQLVCAVLADSEVQAKRAAKRVKIVYQDLEPLILTIEESIQHNSSFKPE RKLEYGNVDEAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDQEMDVYVSTQFPKY IQDIVASTLKLPANKVMCHVRRVGGAFGGKVLKTGIIAAVTAFAANKHGRAVRCVLERGE DMLITGGRHPYLGKYKAGFMNDGRILALDMEHYSNAGASLDESLFVIEMGLLKMDNAYKF PNLRCRGWACRTNLPSNTAFRGFGFPQAALITESCITEVAAKCGLSPEKVRIINMYKEID QTPYKQEINAKNLIQCWRECMAMSSYSLRKVAVEKFNAENYWKKKGLAMVPLKFPVGLGS RAAGQAAALVHIYLDGSVLVTHGGIEMGQGVHTKMIQVVSRELRMPMSNVHLRGTSTETV PNANISGGSVVADLNGLAVKDACQTLLKRLEPIISKNPKGTWKDWAQTAFDESINLSAVG YFRGYESDMNWEKGEGQPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGCSINPAID IGQIEGAFIQGMGLYTIEELNYSPQGILHTRGPDQYKIPAICDMPTELHIALLPPSQNSN TLYSSKGLGESGVFLGCSVFFAIHDAVSAARQERGLHGPLTLNSPLTPEKIRMACEDKFT KMIPRDEPGSYVPWNVPI > DME ID: DME0053 DME Name: Dihydrothymine dehydrogenase (DPYD) PDB ID: Not Available MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDN PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIPQIRNPSLPPPE KMSEAYSAKIALFGAGPASISCASFLARLGYSDITIFEKQEYVGGLSTSEIPQFRLPYDV VNFEIELMKDLGVKIICGKSLSVNEMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQGLTQD QGFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARRVF IVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKGGRIVAMQFVRTEQDETGKWN EDEDQMVHLKADVVISAFGSVLSDPKVKEALSPIKFNRWGLPEVDPETMQTSEAWVFAGG DVVGLANTTVESVNDGKQASWYIHKYVQSQYGASVSAKPELPLFYTPIDLVDISVEMAGL KFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMY GPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDS GADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVSI ARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAKRTTYGGVSGTAIRPIALRAVTS IARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIEDYCTGLKALLYL KSIEELQDWDGQSPATVSHQKGKPVPRIAELMDKKLPSFGPYLEQRKKIIAENKIRLKEQ NVAFSPLKRNCFIPKRPIPTIKDVIGKALQYLGTFGELSNVEQVVAMIDEEMCINCGKCY MTCNDSGYQAIQFDPETHLPTITDTCTGCTLCLSVCPIVDCIKMVSRTTPYEPKRGVPLS VNPVC > DME ID: DME0054 DME Name: Carboxylesterase 1 (CES1) PDB ID: 1MX9; 1YA4; 1YA8; 1YAH; 1YAJ; 2DQY; 2DQZ; 2DR0; 2H7C MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP MQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK DKEVAFWTNLFAKKAVEKPPQTEHIEL > DME ID: DME0056 DME Name: Carboxylesterase 3 (CES3) PDB ID: Not Available MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVF LGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSV SEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRL GVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVL SPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEE LVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLD TMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINV PTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRL AFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFR EAWMQFWSETLPSKIQQWHQKQKNRKAQEDL > DME ID: DME0057 DME Name: Carboxylesterase 2 (CES2) PDB ID: Not Available MRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLG IPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMS EDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLG VLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVS PISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEI LAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQ KEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPA LQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEE EQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKK ALPQKIQELEEPEERHTEL > DME ID: DME0058 DME Name: Acetylcholinesterase (ACHE) PDB ID: 1PUV; 1PUW; 1VZJ; 2CLJ; 2X8B; 3LII; 4BDT; 4EY4; 4EY5 MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN QFDHYSKQDRCSDL > DME ID: DME0059 DME Name: Dimethylaniline oxidase 1 (FMO1) PDB ID: Not Available MAKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVS NSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLKHIQFKTKVCSVTKCSDSA VSGQWEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKGQYFHSRQYKHPD IFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQ NMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIR PSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAH LQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPSWF GLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGK WEGARNAIMTQWDRTFKVIKARVVQESPSPFESFLKVFSFLALLVAIFLIFL > DME ID: DME0060 DME Name: Adenosine aminohydrolase (ADA) PDB ID: 1M7M; 3IAR MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG QNL > DME ID: DME0061 DME Name: Sulfotransferase 1E1 (SULT1E1) PDB ID: 1G3M; 1HY3; 4JVL; 4JVM; 4JVN MNSELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMI YKEGDVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEK DCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWE KGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYT TLPDEIMNQKLSPFMRKGITGDWKNHFTVALNEKFDKHYEQQMKESTLKFRTEI > DME ID: DME0062 DME Name: Sulfotransferase 1A2 (SULT1A2) PDB ID: 1Z29 MELIQDISRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM IYQGGDLEKCHRAPIFMRVPFLEFKVPGIPSGMETLKNTPAPRLLKTHLPLALLPQTLLD QKVKVVYVARNAKDVAVSYYHFYHMAKVYPHPGTWESFLEKFMAGEVSYGSWYQHVQEWW ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDLMVEHTSFKEMKKNPMTNY TTVRREFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAKKMAGCSLSFRSEL > DME ID: DME0063 DME Name: Sulfotransferase 1A3 (SULT1A3) PDB ID: 1CJM; 2A3R MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDM IYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLD QKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWW ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNY TTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL > DME ID: DME0064 DME Name: UDP-glucuronosyltransferase 1A8 (UGT1A8) PDB ID: Not Available MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP EVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLF FSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEG AQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVT AYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIV VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0065 DME Name: UDP-glucuronosyltransferase 1A7 (UGT1A7) PDB ID: Not Available MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP EVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLF FSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEG AQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVT AYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIV VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0066 DME Name: UDP-glucuronosyltransferase 2B17 (UGT2B17) PDB ID: Not Available MSLKWMSVFLLMQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLTSSA SILVNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEY SDYNIKLCEDAVLNKKLMRKLQESKFDVLLADAVNPCGELLAELLNIPFLYSLRFSVGYT VEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEV LGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSS GENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQ NDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRT MSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVA AHNLTWIQYHSLDVIAFLLACVATMIFMITKCCLFCFRKLAKTGKKKKRD > DME ID: DME0067 DME Name: NADPH-dependent carbonyl reductase 1 (CBR1) PDB ID: 1WMA; 2PFG; 3BHI; 3BHJ; 3BHM; 4Z3D MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFH QLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRD VCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK KGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKA TKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW > DME ID: DME0068 DME Name: NADPH-dependent carbonyl reductase 3 (CBR3) PDB ID: 2HRB MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFH QLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRN MCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTK NEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDS IRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW > DME ID: DME0069 DME Name: Butyrylcholine esterase (BCHE) PDB ID: 1KCJ; 1P0I; 1P0M; 1P0P; 1P0Q; 1XLU; 1XLV; 1XLW; 2J4C MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIP YAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDC LYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALG FLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPG SHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEI LLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVY GAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDV VGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLER RDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMT KLRAQQCRFWTSFFPKVLEMTGNIDEAEWEWKAGFHRWNNYMMDWKNQFNDYTSKKESCV GL > DME ID: DME0070 DME Name: Xanthine dehydrogenase/oxidase (XDH) PDB ID: 2CKJ; 2E1Q MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT GVPENCKPWSVRV > DME ID: DME0071 DME Name: Cathepsin A (CTSA) PDB ID: 3BP7; 3BXN; 4AZ0; 4AZ3; 4CI9; 4CIA; 4CIB; 4MWS; 4MWT MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSK HLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLI ANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYA GIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHC CSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQD LGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWD MCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKME VQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY > DME ID: DME0072 DME Name: UDP-glucuronosyltransferase 1A6 (UGT1A6) PDB ID: Not Available MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVV PEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIG LYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEH TFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRD VDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHG IVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLL GHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSE DLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDL TWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0073 DME Name: Alcohol dehydrogenase class-V (ADH6) PDB ID: Not Available MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK TQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTG FGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATE CLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASV QLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAV ELMKTGKW > DME ID: DME0074 DME Name: Sulfotransferase 2A1 (SULT2A1) PDB ID: 1EFH; 1J99; 1OV4; 2QP3; 2QP4; 3F3Y; 4IFB MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSK GDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLM RNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFL LLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVV DKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE > DME ID: DME0075 DME Name: UDP-glucuronosyltransferase 1A10 (UGT1A10) PDB ID: Not Available MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMP EVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLF FSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEG AQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVT AYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIV VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGH PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDL ENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTW YQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0076 DME Name: NADPH-cytochrome P450 reductase (CPR) PDB ID: 1B1C; 3FJO; 3QE2; 3QFC; 3QFR; 3QFS; 3QFT; 5EMN; 5FA6 MGDSHVDTSSTVSEAVAEEVSLFSMTDMILFSLIVGLLTYWFLFRKKKEEVPEFTKIQTL TSSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLA DLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEH FNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEES SIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHL MHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHP FPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWV VEARRHILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYET KAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPF IGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQS HKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVD YIKKLMTKGRYSLDVWS > DME ID: DME0077 DME Name: Aldehyde dehydrogenase 2 (ALDH2) PDB ID: 1NZX; 1NZZ; 1O00; 1O01; 1O02; 1O04; 1O05; 1ZUM; 2ONM MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPS TGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLA ALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCG QIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPG FGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADM DWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGP QVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGP VMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQS PFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS > DME ID: DME0078 DME Name: Adenine phosphoribosyltransferase (APRT) PDB ID: 1ZN7; 1ZN8; 1ZN9; 4X44; 4X45; 6FCH; 6FCI; 6FCL; 6FD4 MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDY IAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPG QRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE > DME ID: DME0079 DME Name: Alkaline phosphatase (ALPL) PDB ID: Not Available MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF > DME ID: DME0080 DME Name: Cytidine aminohydrolase (CDA) PDB ID: 1MQ0 MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACY PLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKP DGTYIVMTVQELLPSSFGPEDLQKTQ > DME ID: DME0081 DME Name: Glutathione S-transferase alpha-2 (GSTA2) PDB ID: 1AGS; 2VCT; 2WJU; 4ACS MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF > DME ID: DME0083 DME Name: Methylenetetrahydrofolate reductase (MTHFR) PDB ID: 6FCX MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWF SLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYC GLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVK HIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFV KACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIE LAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREE DVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKM WGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGIL TINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHL VNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYE EESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP > DME ID: DME0084 DME Name: Beta,beta-carotene 15,15'-dioxygenase (BCO1) PDB ID: Not Available MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG VTENYVIFLEQPFRLDILKMATAYIRRMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY VFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS TDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQAASEEQRDRASD CHGAPLT > DME ID: DME0086 DME Name: Bleomycin hydrolase (BLMH) PDB ID: 1CB5; 2CB5 MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQE GKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVD TAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDI LNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDK NYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLY NNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKA ERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVY EVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE > DME ID: DME0087 DME Name: Aldo-keto reductase 1B1 (AKR1B1) PDB ID: 1AZ1; 1AZ2; 1EF3; 1EL3; 1IEI; 1MAR; 1PWL; 1PWM; 1T40 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA LLSCTSHKDYPFHEEF > DME ID: DME0088 DME Name: Glutathione S-transferase pi (GSTP1) PDB ID: 12GS; 13GS; 14GS; 16GS; 17GS; 18GS; 19GS; 1AQV; 1AQW MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGD LTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYV KALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAY VGRLSARPKLKAFLASPEYVNLPINGNGKQ > DME ID: DME0089 DME Name: Microsomal glutathione S-transferase 2 (MGST2) PDB ID: Not Available MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFY PIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTL LGALGIANSFLDEYLDLNIAKKLRRQF > DME ID: DME0090 DME Name: Catalase (CAT) PDB ID: 1DGB; 1DGF; 1DGG; 1DGH; 1F4J; 1QQW MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDE MAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGES GSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPD MVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQ GIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLT KVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPD THRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALE HSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVK NFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL > DME ID: DME0091 DME Name: Prostaglandin G/H synthase 1 (COX-1) PDB ID: Not Available MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL > DME ID: DME0092 DME Name: Thymidine phosphorylase (TYMP) PDB ID: 1UOU; 2J0F; 2WK5; 2WK6 MAALMTPGTGAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAA VVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGG VGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQA GCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAA VFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPP DLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARAL CSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVG AELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPP QQ > DME ID: DME0093 DME Name: Glutathione S-transferase theta-1 (GSTT1) PDB ID: 2C3N; 2C3Q; 2C3T MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDG DFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMF PVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGA GCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVLAMIR > DME ID: DME0094 DME Name: Metallothionein-1A (MT1A) PDB ID: Not Available MDPNCSCATGGSCTCTGSCKCKECKCTSCKKSCCSCCPMSCAKCAQGCICKGASEKCSCC A > DME ID: DME0095 DME Name: Metallothionein-2A (MT2A) PDB ID: 1MHU; 2MHU MDPNCSCAAGDSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCC A > DME ID: DME0096 DME Name: Myeloperoxidase (MPO) PDB ID: 1D5L; 1D7W; 1DNU; 1DNW; 1MHL; 1MYP; 3F9P; 3ZS0; 3ZS1 MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTS LVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLH VALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMC NNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTD QLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIPPND PRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQL GLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLL REHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYR SYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLE GGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYN AWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPL LACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMS NSYPRDFVNCSTLPALNLASWREAS > DME ID: DME0097 DME Name: Quinone reductase 1 (NQO1) PDB ID: 1GG5; 1H66; 1H69; 1KBO; 1KBQ; 1QBG; 2F1O; 3JSX; 4CET MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK > DME ID: DME0098 DME Name: Aldo-keto reductase 1A1 (AKR1A1) PDB ID: 2ALR MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV PMLTVDGKRVPRDAGHPLYPFNDPY > DME ID: DME0099 DME Name: Cholesterol desmolase (CYP11A1) PDB ID: 3N9Y; 3N9Z; 3NA0; 3NA1 MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWL NLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPER FLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVS VLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQM FHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRG ILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAAR HQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIY ALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINML ENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ > DME ID: DME0100 DME Name: Vitamin D 25-hydroxylase (CYP2R1) PDB ID: 3C6G; 3CZH; 3DL9 MWKLWRAEEGAAALGGALFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSE LPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTK MGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFK QLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPF GKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENL IFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPY TEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVF HPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPD LKPRLGMTLQPQPYLICAERR > DME ID: DME0101 DME Name: Choline dehydrogenase (CHDH) PDB ID: Not Available MWCLLRGLGRPGALARGALGQQQSLGARALASAGSESRDEYSYVVVGAGSAGCVLAGRLT EDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVL YWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQGHELGASRY RGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSA ACAYLHPALSRTNLKAEAETLVSRVLFEGTRAVGVEYVKNGQSHRAYASKEVILSGGAIN SPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHSAQKPLR KVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHGRVPTQQEAY QVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAP FRGKELQPGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENL RVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKDVPVYKPRTLATQR > DME ID: DME0102 DME Name: Choline O-acetyltransferase (CHAT) PDB ID: 2FY2; 2FY3; 2FY4; 2FY5 MGLRTAKKRGLGGGGKWKREEGGGTRGRREVRPACFLQSGGRGDPGDVGGPAGNPGCSPH PRAATRPPPLPAHTPAHTPEWCGAASAEAAEPRRAGPHLCIPAPGLTKTPILEKVPRKMA AKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQ QKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLIS GVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPE PEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSE WAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGANR WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHVTQSSRKLIRADSVSELPAP RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQV PTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRD LCSLLPPTESKPLATKEKATRPSQGHQP > DME ID: DME0103 DME Name: Choline/ethanolaminephosphotransferase 1 (CEPT1) PDB ID: Not Available MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAG RSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYI ACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPD WMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIP VLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLA AMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLD QYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKVSTAHSNHH > DME ID: DME0104 DME Name: Alpha-L-iduronidase (IDUA) PDB ID: 3W82; 4KGJ; 4KGL; 4KH2; 4MJ2; 4MJ4; 4OBR; 4OBS; 6I6R MRPLRPRAALLALLASLLAAPPVAPAEAPHLVHVDAARALWPLRRFWRSTGFCPPLPHSQ ADQYVLSWDQQLNLAYVGAVPHRGIKQVRTHWLLELVTTRGSTGRGLSYNFTHLDGYLDL LRENQLLPGFELMGSASGHFTDFEDKQQVFEWKDLVSSLARRYIGRYGLAHVSKWNFETW NEPDHHDFDNVSMTMQGFLNYYDACSEGLRAASPALRLGGPGDSFHTPPRSPLSWGLLRH CHDGTNFFTGEAGVRLDYISLHRKGARSSISILEQEKVVAQQIRQLFPKFADTPIYNDEA DPLVGWSLPQPWRADVTYAAMVVKVIAQHQNLLLANTTSAFPYALLSNDNAFLSYHPHPF AQRTLTARFQVNNTRPPHVQLLRKPVLTAMGLLALLDEEQLWAEVSQAGTVLDSNHTVGV LASAHRPQGPADAWRAAVLIYASDDTRAHPNRSVAVTLRLRGVPPGPGLVYVTRYLDNGL CSPDGEWRRLGRPVFPTAEQFRRMRAAEDPVAAAPRPLPAGGRLTLRPALRLPSLLLVHV CARPEKPPGQVTRLRALPLTQGQLVLVWSDEHVGSKCLWTYEIQFSQDGKAYTPVSRKPS TFNLFVFSPDTGAVSGSYRVRALDYWARPGPFSDPVPYLEVPVPRGPPSPGNP > DME ID: DME0105 DME Name: Arylsulfatase B (ARSB) PDB ID: 1FSU MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD PEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM > DME ID: DME0106 DME Name: Beta-glucuronidase (GUSB) PDB ID: 1BHG; 3HN3 MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFE EQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVV LRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTT LPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQD SGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYL YSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKG FDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNN VSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVT FVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSE YGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTR VLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSLFT > DME ID: DME0107 DME Name: N-acetyl-beta-glucosaminidase beta (HEXB) PDB ID: 1NOU; 1NOW; 1NP0; 1O7A; 1QBD; 2GJX; 2GK1; 3LMY; 5BRO MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEAARAPSVSAKPGPALWPLP LSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHEPAEFQA KTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY QDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVD DQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGK GQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKC WESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTI VEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTQKQKQL FIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLTRHRCRMVERG IAAQPLYAGYCNHENM > DME ID: DME0108 DME Name: Iduronate 2-sulfatase (IDS) PDB ID: 5FQL; 6IOZ MPPPRTGRGLLWLGLVLSSVCVALGSETQANSTTDALNVLLIIVDDLRPSLGCYGDKLVR SPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHAGNFSTIP QYFKENGYVTMSVGKVFHPGISSNHTDDSPYSWSFPPYHPSSEKYENTKTCRGPDGELHA NLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQK LYPLENITLAPDPEVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVDFQRKIRQSY FASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHGWALGEHGEWAKYSNFDVATHVPLI FYVPGRTASLPEAGEKLFPYLDPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVPP RCPVPSFHVELCREGKNLLKHFRFRDLEEDPYLPGNPRELIAYSQYPRPSDIPQWNSDKP SLKDIKIMGYSIRTIDYRYTVWVGFNPDEFLANFSDIHAGELYFVDSDPLQDHNMYNDSQ GGDLFQLLMP > DME ID: DME0109 DME Name: Superoxide dismutase 1 (SOD1) PDB ID: 2VR8; 2WKO; 3RE0; 3T5W; 4A7G; 5YTU; 5YUL; 6A9O; 6B79 MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ > DME ID: DME0110 DME Name: Glutathione reductase (GSR) PDB ID: 1DNC; 1GRA; 1GRB; 1GRE; 1GRF; 1GRG; 1GRH; 1GRT; 1GSN MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR > DME ID: DME0111 DME Name: Ecto-5'-nucleotidase (NT5E) PDB ID: 4H1S; 4H1Y; 4H2B; 4H2F; 4H2G; 4H2I; 6HXW MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGG VARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEF DNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKE TPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVV GGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNV ISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNM GNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGT FDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCR VPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYP AVEGRIKFSTGSHCHGSFSLIFLSLWAVIFVLYQ > DME ID: DME0112 DME Name: Deoxycytidylate deaminase (DCTD) PDB ID: 2W4L MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGC SDDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQA GIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ > DME ID: DME0113 DME Name: Heparanase (HPSE) PDB ID: 5E8M; 5E97; 5E98; 5E9B; 5E9C; 5L9Y; 5L9Z; 5LA4; 5LA7 MLLRSKPALPPPLMLLLLGPLGPLSPGALPRPAQAQDVVDLDFFTQEPLHLVSPSFLSVT IDANLATDPRFLILLGSPKLRTLARGLSPAYLRFGGTKTDFLIFDPKKESTFEERSYWQS QVNQDICKYGSIPPDVEEKLRLEWPYQEQLLLREHYQKKFKNSTYSRSSVDVLYTFANCS GLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADIFINGS QLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLKSFLKAGGEVIDSVTWHHYYL NGRTATKEDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGAPLLSDTFA AGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKKLVGTKVLM ASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLHNVTKYLRLPYPFSNKQVDKYLL RPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYSFFVIRNAKVA ACI > DME ID: DME0114 DME Name: Prostaglandin G/H synthase 2 (COX-2) PDB ID: 1V0X; 5F19; 5F1A; 5IKQ; 5IKR; 5IKT; 5IKV; 5KIR MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFL TRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADY GYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGS NMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKY QIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCD VLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQ NRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRV AGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEAL YGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEV GFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKER STEL > DME ID: DME0116 DME Name: Alpha-methylacyl-CoA racemase (AMACR) PDB ID: Not Available MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQP RGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLA GHDINYLALSGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVI DANMVEGTAYLSSFLWKTQKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQF YELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDACVTPVLTF EEVVHHDHNKERGSFITSEEQDVSPRPAPLLLNTPAIPSFKRDPFIGEHTEEILEEFGFS REEIYQLNSDKIIESNKVKASL > DME ID: DME0117 DME Name: Dehydropeptidase-I (DPEP1) PDB ID: 1ITQ; 1ITU MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTT LAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVT SSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLV DTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYS VCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVG FGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLT QAPEEEPIPLDQLGGSCRTHYGYSSGASSLHRHWGLLLASLAPLVLCLSLL > DME ID: DME0118 DME Name: Aldo-keto reductase 1C3 (AKR1C3) PDB ID: 1S1P; 1S1R; 1S2A; 1S2C; 1XF0; 1ZQ5; 2F38; 2FGB; 3R43 MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD RNLHYFNSDSFASHPNYPYSDEY > DME ID: DME0119 DME Name: NADH-ubiquinone oxidoreductase 49 kDa (NDUFS2) PDB ID: 5XTB; 5XTC; 5XTD; 5XTH; 5XTI MAALRALCGFRGVAAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGAVMYPSKETAH WKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIRPPPRAQWIRVLFGEITRL LNHIMAVTTHALDLGAMTPFFWLFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGL MDDIYQFSKNFSLRLDELEELLTNNRIWRNRTIDIGVVTAEEALNYGFSGVMLRGSGIQW DLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIAQCLNKMPPGEIKVDD AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR > DME ID: DME0120 DME Name: NADH-ubiquinone oxidoreductase 30 kDa (NDUFS3) PDB ID: 5XTB; 5XTD; 5XTH; 5XTI MAAAAVARLWWRGILGASALTRGTGRPSVLLLPVRRESAGADTRPTVRPRNDVAHKQLSA FGEYVAEILPKYVQQVQVSCFNELEVCIHPDGVIPVLTFLRDHTNAQFKSLVDLTAVDVP TRQNRFEIVYNLLSLRFNSRIRVKTYTDELTPIESAVSVFKAANWYEREIWDMFGVFFAN HPDLRRILTDYGFEGHPFRKDFPLSGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWE AFPVYRQPPESLKLEAGDKKPDAK > DME ID: DME0121 DME Name: NADH-ubiquinone oxidoreductase 20 kDa (NDUFS7) PDB ID: 5XTB; 5XTD; 5XTH; 5XTI MAVLSAPGLRGFRILGLRSSVGPAVQARGVHQSVATDGPSSTQPALPKARAVAPKPSSRG EYVVAKLDDLVNWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQSDVM IVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYI PGCPPTAEALLYGILQLQRKIKRERRLQIWYRR > DME ID: DME0122 DME Name: Nitric oxide synthase brain (NOS1) PDB ID: 4UH5; 4UH6; 4V3U; 5ADF; 5ADG; 5ADI; 5FVU; 5FVV; 5FVW MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF GHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN SLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFV RLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGV ISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEY EEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV SYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAP FRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSRE PDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAE DAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS > DME ID: DME0123 DME Name: Nitric oxide synthase endothelial (NOS3) PDB ID: 1M9M; 1M9Q; 1M9R; 1NIW; 2LL7; 2MG5; 2N8J; 3EAH; 3NOS MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLT QPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRN APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPP ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA RDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATIL VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP PPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVL AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDT NSP > DME ID: DME0124 DME Name: Nitric oxide synthase inducible (NOS2) PDB ID: 1NSI; 2LL6; 2NSI; 3E7G; 3EJ8; 4CX7; 4NOS; 5TP6; 5XN3 MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLSKQQNESPQPL VETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIM TPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNI RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG RFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINI AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEM LNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVT ILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPG NGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGD ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDL SKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQ PALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQ LLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL PILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCF VRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPD EDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLY VCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDR VAVQPSSLEMSAL > DME ID: DME0125 DME Name: DOPA decarboxylase (DDC) PDB ID: 3RBF; 3RBL; 3RCH MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE > DME ID: DME0126 DME Name: L-glutamine amidohydrolase (GLS) PDB ID: 3UO9; 3VOY; 3VOZ; 3VP0; 3VP1; 3VP2; 3VP3; 3VP4; 4O7D MMRLRGSGMLRDLLLRSPAGVSATLRRAQPLVTLCRRPRGGGRPAAGPAAAARLHPWWGG GGWPAEPLARGLSSSPSEILQELGKGSTHPQPGVSPPAAPAAPGPKDGPGETDAFGNSEG KELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMD MLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKK QSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDL GTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQ FLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSI EVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPA KSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKL DPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVE VVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQT VHKNLDGLL > DME ID: DME0127 DME Name: Alcohol dehydrogenase class-I alpha (ADH1A) PDB ID: 1HSO; 1U3T MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF DLLHSGKSIRTILMF > DME ID: DME0128 DME Name: Alcohol dehydrogenase class-I beta (ADH1B) PDB ID: 1DEH; 1HDX; 1HDY; 1HDZ; 1HSZ; 1HTB; 1U3U; 1U3V; 3HUD MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVT PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF DLLHSGKSIRTVLTF > DME ID: DME0129 DME Name: Alcohol dehydrogenase class-I gamma (ADH1C) PDB ID: 1DDA; 1HT0; 1U3W MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF DLLRSGKSIRTVLTF > DME ID: DME0130 DME Name: Alcohol dehydrogenase class-II (ADH4) PDB ID: 3COS MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK ISEAFDLMNQGKSVRTILIF > DME ID: DME0131 DME Name: Gastric alcohol dehydrogenase (ADH7) PDB ID: 1AGN; 1D1S; 1D1T MFAEIQIQDKDRMGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICR TDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPD GNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEK VCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK FEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGT SVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITH VLPFKKISEGFELLNSGQSIRTVLTF > DME ID: DME0132 DME Name: Alcohol dehydrogenase class-III (ADH5) PDB ID: 1M6H; 1M6W; 1MA0; 1MC5; 1MP0; 1TEH; 2FZE; 2FZW; 3QJ5 MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGC FPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGK GLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGY GAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATEC INPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEE IATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFE LMHSGKSIRTVVKI > DME ID: DME0133 DME Name: Dipeptidyl peptidase IV (DPP4) PDB ID: 1NU6; 1NU8; 1PFQ; 1R9M; 1R9N; 1RWQ; 1TK3; 1TKR; 1U8E MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSL RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN EYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY TLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKY PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS KALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP > DME ID: DME0135 DME Name: Cytochrome P450 4F12 (CYP4F12) PDB ID: Not Available MSLLSLPWLGLRPVATSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF WGHLGLITPTEEGLKNSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH LASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ > DME ID: DME0136 DME Name: Amidophosphoribosyltransferase (GPAT) PDB ID: Not Available MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW > DME ID: DME0137 DME Name: Thymidylate synthase (TYMS) PDB ID: 1JUJ; 1YPV; 2ONB; 2RD8; 3OB7; 4E28; 4FGT; 5X69; 6OJU MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG YNPHPTIKMEMAV > DME ID: DME0138 DME Name: Uridine 5'-monophosphate synthase (UMPS) PDB ID: 2QCD; 2QCE; 3BGG; 3L0N; 3MI2; 3MO7; 3MW7; 4HIB; 4HKP MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQT AQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCL IIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKML EILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVA SKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELIT LAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLP LHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQ LEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV > DME ID: DME0139 DME Name: Uridine phosphorylase 1 (UPP1) PDB ID: 3EUE; 3EUF; 3NBQ MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS YFIKKKLSKA > DME ID: DME0140 DME Name: Uridine phosphorylase 2 (UPP2) PDB ID: 2XRF; 3P0E; 3P0F MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVK FVCVGGSPNRMKAFALFMHKELGFEEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPS ISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDN IVTRSTELDKELSEELFNCSKEIPNFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLD YLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQR PQLLISNFIRRRLGLCD > DME ID: DME0141 DME Name: Dihydrofolate reductase (DHFR) PDB ID: 1DLR; 1DLS; 1DRF; 1HFP; 1HFQ; 1HFR; 1KMS; 1KMV; 1MVS MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFS IPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSS VYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF EVYEKND > DME ID: DME0142 DME Name: Gamma-Glu-X carboxypeptidase (GGH) PDB ID: 1L9X MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCRNKVMKNYGRYYIAASY VKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLRRSDYAKVAKIFYNLSIQ SFDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAMPLNFTGGQLHSRMFQNFPTE LLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYG VQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQF SPIYTGNISSFQQCYIFD > DME ID: DME0143 DME Name: Histamine N-methyltransferase (HNMT) PDB ID: 1ICZ; 1JQD; 1JQE; 2AOT; 2AOU; 2AOV; 2AOW; 2AOX MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG GGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETS SEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWD KLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLL WDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA > DME ID: DME0144 DME Name: Alpha-N-acetylglucosaminidase (NAG) PDB ID: 4XWH MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKP GLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGE LTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYL ALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTP VLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELI KEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQF WGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGAL EAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAA RRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAW RLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAY ELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYAN KQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPR GDTVDLAKKIFLKYYPRWVAGSW > DME ID: DME0145 DME Name: Alanyl aminopeptidase (ANPEP) PDB ID: 4FYQ; 4FYR; 4FYS; 4FYT; 5LHD; 6ATK; 6U7E; 6U7F; 6U7G MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPA SATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVI IIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDS EFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHP KDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLI RIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLV TYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYL GADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKG ASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIM NRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDY WLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQ IINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKN YLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWM ENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWI LNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSN LIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQ WFTENSK > DME ID: DME0146 DME Name: Phosphoglucomutase 1 (PGM1) PDB ID: 5EPC; 5F9C; 5HSH; 5JN5; 5VBI; 5VEC; 5VG7; 5VIN; 6BJ0 MVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVG GDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNP GGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDLKVDLGVLGKQQFDLENK FKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEE LGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKH GFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWK FFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWQKY GRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPV DGSISRNQGLRLIFTDGSRIVFRLSGTGSAGATIRLYIDSYEKDVAKINQDPQVMLAPLI SIALKVSQLQERTGRTAPTVIT > DME ID: DME0147 DME Name: Cellular glutathione peroxidase (GPX1) PDB ID: 2F8A MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMN ELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGA GAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYS RRFQTIDIEPDIEALLSQGPSCA > DME ID: DME0148 DME Name: Pancreatic alpha-amylase (AMY2A) PDB ID: 1CPU; 1HNY; 1KB3; 1KBB; 1KBK; 1KGU; 1KGW; 1KGX; 1U2Y MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPP NENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGN AVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGL LDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAG SKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWG FVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWP RQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQP FTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGI KIYVSDDGKAHFSISNSAEDPFIAIHAESKL > DME ID: DME0149 DME Name: Vitamin K1 2,3-epoxide reductase 1 (VKOR) PDB ID: Not Available MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWG RGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYL AWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH > DME ID: DME0150 DME Name: Deoxy-5'-nucleotidase 1 (NT5C) PDB ID: 2I7D; 4L57; 4YIH; 6G2N MARSVRVLVDMDGVLADFEAGLLRGFRRRFPEEPHVPLEQRRGFLAREQYRALRPDLADK VASVYEAPGFFLDLEPIPGALDAVREMNDLPDTQVFICTSPLLKYHHCVGEKYRWVEQHL GPQFVERIILTRDKTVVLGDLLIDDKDTVRGQEETPSWEHILFTCCHNRHLVLPPTRRRL LSWSDNWREILDSKRGAAQRE > DME ID: DME0151 DME Name: Phosphorylcholine transferase A (PCYT1A) PDB ID: Not Available MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD ISEDEED > DME ID: DME0152 DME Name: Phosphorylethanolamine transferase (PCYT2) PDB ID: 3ELB; 4XSV MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDE EIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTV DGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKC PGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLA ERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHF KVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITNRLEYEARN QKKEAKELAFLEAARQQAAQPLGERDGDF > DME ID: DME0153 DME Name: Vitamin B12 methionine synthase (MTR) PDB ID: 2O2K; 4CCZ MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHA RPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMC SAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQA KGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQT GEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDET PSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGL EPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDG MLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDD FLEKARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNI LTIGTGMEEHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLY HAIKSGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKV IQTDEWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVG DLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATV KGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEM IFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDEN LKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQV FEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNMLNTL ISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYY CLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEE LHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTG IRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPIL GYDTD > DME ID: DME0154 DME Name: Asparagine synthetase (ASNS) PDB ID: 6GQ3 MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQ PIRVKKYPYLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGV FAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPF LPGHYEVLDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIETVKNNLRILFN NAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGMEDSPDLLAAR KVADHIGSEHYEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVV IFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLRELYLFDVLRADRTTAAHGLELRVPF LDHRFSSYYLSLPPEMRIPKNGIEKHLLRETFEDSNLIPKEILWRPKEAFSDGITSVKNS WFKILQEYVEHQVDDAMMANAAQKFPFNTPKTKEGYYYRQVFERHYPGRADWLSHYWMPK WINATDPSARTLTHYKSAVKA > DME ID: DME0155 DME Name: Glutamine-dependent NAD(+) synthetase (NADSYN1) PDB ID: Not Available MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYES DTLLHSFQVLAALVESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANE GNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWT PHSPHIDMGLDGVEIITNASGSHQVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRL YYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPR VKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGV DSAATACLIYSMCCQVCEAVRSGNEEVLADVRTIVNQISYTPQDPRDLCGRILTTCYMAS KNSSQETCTRARELAQQIGSHHISLNIDPAVKAVMGIFSLVTGKSPLFAAHGGSSRENLA LQNVQARIRMVLAYLFAQLSLWSRGVHGGLLVLGSANVDESLLGYLTKYDCSSADINPIG GISKTDLRAFVQFCIQRFQLPALQSILLAPATAELEPLADGQVSQTDEEDMGMTYAELSV YGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFFSKYSMNRHKMTTLTPAYHAE NYSPEDNRFDLRPFLYNTSWPWQFRCIENQVLQLERAEPQSLDGVD > DME ID: DME0156 DME Name: Hexosephosphate aminotransferase 2 (GFPT2) PDB ID: Not Available MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNHEVKERHIQLVKKR GKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHN GIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEG AFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILYRTCTLENVKNICKTRMK RLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSAS DDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDH LKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFF ISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYT SQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLEEKIHDLALELYTQRS LLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCF AKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFH LAVLRGYDVDFPRNLAKSVTVE > DME ID: DME0157 DME Name: Glutaminyl-tRNA synthetase (GLNRS) PDB ID: 4R3Z; 4YE6; 4YE8; 4YE9 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV > DME ID: DME0158 DME Name: Glutamyl-tRNA(Gln) amidotransferase B (GATB) PDB ID: Not Available MAAPMLRWGCRGRRWAFARVDGGSCHRRGAPTGSTSNQIRGESSVAQQPLHTAQKTRKGE HKWAAVVGLEIHAQISSNSKLFSGSQVRFSAPPNSLVSFFDASLPGTLPVLNRRCVEAAV MTGLALNCHINKKSLFDRKHYFYADLPAGYQITQQRLPIAVNGSLIYGVCAGKKQSQVIP KTVRIKQIQLEQDSGKSLHDNLRSQTLIDLNRAGVGLLEVVLEPDMSCGEEAATAVRELQ LILQALGTSQANMAEGQLRVDANISVHHPGEPLGVRTEVKNLNSIRFLAKAIDYEIQRQI NELENGGEILNETRSFHHKLGCTMSMRDKEGKQDYRFMPEPNLPPLVLYDATSLPAGADP QQVINIDQIRETLPELPSVTREKLVQQYGMLLEHSFTLLNEVGLLEFFQNVIKETRAEPK KVTSWVLNTFLGYLKQQNLAVSESPVTPSALAELLDLLDSRTISSSAAKQVFEELWKREG KTPGQIVSEKQLELMQDQGALEQLCHSVMEAHPQVVMDVKNRNPRAINKLIGLVRKATQS RADPVMIKEILEKKLSL > DME ID: DME0159 DME Name: Glutamine amidotransferase (GMPS) PDB ID: 2VPI; 2VXO MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETP AFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHK KSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANE SKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVL VLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAA HSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPE EVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVR ILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPH TLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDW ESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILR ESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVE VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE > DME ID: DME0160 DME Name: Kynurenine aminotransferase I (KYAT1) PDB ID: 1W7L; 1W7M; 1W7N; 3FVS; 3FVU; 3FVX; 4WLH; 4WLJ; 4WP0 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV EL > DME ID: DME0161 DME Name: Phosphoribosylformylglycinamidine synthase (PFAS) PDB ID: Not Available MSPVLHFYVRPSGHEGAAPGHTRRKLQGKLPELQGVETELCYNVNWTAEALPSAEETKKL MWLFGCPLLLDDVARESWLLPGSNDLLLEVGPRLNFSTPTSTNIVSVCRATGLGPVDRVE TTRRYRLSFAHPPSAEVEAIALATLHDRMTEQHFPHPIQSFSPESMPEPLNGPINILGEG RLALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEAFDLAQSNSEHSRHWFFKGQLH VDGQKLVHSLFESIMSTQESSNPNNVLKFCDNSSAIQGKEVRFLRPEDPTRPSRFQQQQG LRHVVFTAETHNFPTGVCPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY NLPWEDPSFQYPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW IKPIMFSGGIGSMEADHISKEAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLD FGAVQRGDPEMEQKMNRVIRACVEAPKGNPICSLHDQGAGGNGNVLKELSDPAGAIIYTS RFQLGDPTLNALEIWGAEYQESNALLLRSPNRDFLTHVSARERCPACFVGTITGDRRIVL VDDRECPVRRNGQGDAPPTPLPTPVDLELEWVLGKMPRKEFFLQRKPPMLQPLALPPGLS VHQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHEELIG AATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAA LADACEAMVAVMAALGVAVDGGKDSLSMAARVGTETVRAPGSLVISAYAVCPDITATVTP DLKHPEGRGHLLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLK DRLLCSGHDVSDGGLVTCLLEMAFAGNCGLQVDVPVPRVDVLSVLFAEEPGLVLEVQEPD LAQVLKRYRDAGLHCLELGHTGEAGPHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDR LQAEPRCVAEEERGLRERMGPSYCLPPTFPKASVPREPGGPSPRVAILREEGSNGDREMA DAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPRAG AELRRFRKRPDTFSLGVCNGCQLLALLGWVGGDPNEDAAEMGPDSQPARPGLLLRHNLSG RYESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYVAFSSPELQAQIEARGLAPLHWA DDDGNPTEQYPLNPNGSPGGVAGICSCDGRHLAVMPHPERAVRPWQWAWRPPPFDTLTTS PWLQLFINARNWTLEGSC > DME ID: DME0162 DME Name: Transglutaminase H (TGM2) PDB ID: 1FAU; 1KV3; 2Q3Z; 3LY6; 3S3J; 3S3P; 3S3S; 4PYG; 6A8P MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG LHKLVVNFESDKLKAVKGFRNVIIGPA > DME ID: DME0163 DME Name: Transglutaminase X (TGM5) PDB ID: Not Available MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFV VETGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIH IDSFQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCP WNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNG NWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVIT NFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLD ATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDT SSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQP SRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLK VNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALG EEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGS GLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL > DME ID: DME0164 DME Name: Transglutaminase Y (TGM6) PDB ID: Not Available MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMET GPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSS HRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYG QFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQG KYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNS AHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQ EESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKI GRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGRC LWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTR KPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGEKLLVEK DITLEDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVPTL EPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATAK > DME ID: DME0165 DME Name: Transglutaminase E (TGM3) PDB ID: 1L9M; 1L9N; 1NUD; 1NUF; 1NUG MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVST GPYPSESAMTKAVFPLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQ GGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQ FEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGT YTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSA HDTDRNLSVDVYYDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQER SQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIG RYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQE PSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSAT MSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDESEVVVERDIILDNPTLTLE VLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKEGSRVRFD ILPSRSGTKQLLADFSCNKFPAIKAMLSIDVAE > DME ID: DME0166 DME Name: Transglutaminase K (TGM1) PDB ID: 2XZZ MMDGPRSDVGRWGGNPLQPPTTPSPEPEPEPDGRSRRGGGRSFWARCCGCCSCRNAADDD WGPEPSDSRGRGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSS RSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTH VIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPR NEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDA CLYILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVE ILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDEN MKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESI KNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAISSNMREDI TYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMGQDLMVSVML INHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLV DQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVT LTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHG VIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA > DME ID: DME0167 DME Name: Transglutaminase Z (TGM7) PDB ID: Not Available MDQVATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRPFQSQNDHITF VAETGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKI EISQGQGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSW PWNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQ GNWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVV SNFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVL DPTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEILAH NTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLL ESGGLRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLHGG GTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGRSMLVL KDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIAKDLG TLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVTVAGAP > DME ID: DME0168 DME Name: Neprilysin (MME) PDB ID: 1QVD; 1R1H; 1R1I; 1R1J; 1Y8J; 2QPJ; 2YB9; 4CTH; 5JMY MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSS DCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKD VLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGA SWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKE ACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLY NKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILT KYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNME NAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERI GYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAA VVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKD GDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYR AYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRII GTLQNSAEFSEAFHCRKNSYMNPEKKCRVW > DME ID: DME0169 DME Name: Serum paraoxonase/arylesterase 1 (PON1) PDB ID: 1V04; 1XHR MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL > DME ID: DME0170 DME Name: Serum paraoxonase/lactonase 3 (PON3) PDB ID: Not Available MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL > DME ID: DME0171 DME Name: Indoleamine 2,3-dioxygenase 1 (IDO1) PDB ID: 4PK5; 4PK6; 4U72; 4U74; 5EK2; 5EK3; 5EK4; 5ETW; 5WHR MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG > DME ID: DME0172 DME Name: Tryptophan oxygenase (TRPO) PDB ID: 4PW8; 5TI9; 5TIA; 6A4I MSGCPFLGNNFGYTFKKLPVEGSEEDKSQTGVNRASKGGLIYGNYLHLEKVLNAQELQSE TKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVSRMHRVSV ILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHY RDNFKGEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEEFIR IQAKEESEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYRE EPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSKAGTGGSSGYHYLRSTVSDRYK VFVDLFNLSTYLIPRHWIPKMNPTIHKFLYTAEYCDSSYFSSDESD > DME ID: DME0173 DME Name: Tryptophan 5-hydroxylase 1 (TPH1) PDB ID: 1IN9; 1MLW; 3HF6; 3HF8; 3HFB; 5J6D; 5L01; 5TPG MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF EIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCAN RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQE LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD FLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITC KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA MNELQHDLDVVSDALAKVSRKPSI > DME ID: DME0174 DME Name: Tryptophan 5-hydroxylase 2 (TPH2) PDB ID: 4V06 MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGSSTLNKPNSGKNDDKGNKGSSKREAATE SGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFN ELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHP GFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYL KNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQ YIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFF TIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYF VSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDA LNKMNQYLGI > DME ID: DME0175 DME Name: Tryptophanyl-tRNA synthetase cytoplasmic (WARS1) PDB ID: 1O5T; 1R6T; 1R6U; 1ULH; 2AKE; 2QUJ; 2QUK; 5UJI; 5UJJ MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKA DCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRI ERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDY MGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDR TDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIF LTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDY TSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ > DME ID: DME0176 DME Name: Tryptophanyl-tRNA synthetase mitochondrial (WARS2) PDB ID: 5EKD MALHSMRKARERWSFIRALHKGSAAAPALQKDSKKRVFSGIQPTGILHLGNYLGAIESWV RLQDEYDSVLYSIVDLHSITVPQDPAVLRQSILDMTAVLLACGINPEKSILFQQSQVSEH TQLSWILSCMVRLPRLQHLHQWKAKTTKQKHDGTVGLLTYPVLQAADILLYKSTHVPVGE DQVQHMELVQDLAQGFNKKYGEFFPVPESILTSMKKVKSLRDPSAKMSKSDPDKLATVRI TDSPEEIVQKFRKAVTDFTSEVTYDPAGRAGVSNIVAVHAAVTGLSVEEVVRRSAGMNTA RYKLAVADAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELAYTVCQEVKKLVGFL > DME ID: DME0177 DME Name: Cytosolic branched aminotransferase (BCAT1) PDB ID: 2ABJ; 2COG; 2COI; 2COJ MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK LASRILSKLTDIQYGREESDWTIVLS > DME ID: DME0178 DME Name: Propionyl-CoA carboxylase beta (PCCB) PDB ID: Not Available MAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGGGQRRIDAQHK RGKLTARERISLLLDPGSFVESDMFVEHRCADFGMAADKNKFPGDSVVTGRGRINGRLVY VFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIF LRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVT QEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVP ELDTIVPLESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVGFARMNGRTVGIVGNQPK VASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFA EATVPKVTVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIFKGHENVE AAQAEYIEKFANPFPAAVRGFVDDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL > DME ID: DME0179 DME Name: Valyl-tRNA synthetase (VARS) PDB ID: Not Available MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRTPFPPPRLPAL EQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALG LRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLLPFRYVLDPPA RRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPALPKTAAQLKKEAKK REKLEKFQQKQKIQQQQPPPGEKKPKPEKREKRDPGVITYDLPTPPGEKKDVSGPMPDSY SPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAI QDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWREQGLSRHQLGREAFLQEVWKWK EEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCT LNSAISDIEVDKKELTGRTLLSVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIET MLGDVAVAVHPKDTRYQHLKGKNVIHPFLSRSLPIVFDEFVDMDFGTGAVKITPAHDQND YEVGQRHGLEAISIMDSRGALINVPPPFLGLPRFEARKAVLVALKERGLFRGIEDNPMVV PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHAWMDNIREWC ISRQLWWGHRIPAYFVTVSDPAVPPGEDPDGRYWVSGRNEAEAREKAAKEFGVSPDKISL QQDEDVLDTWFSSGLFPLSILGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKL TGRLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIYGISLQGLHNQLLNSNLDPSEVE KAKEGQKADFPAGIPECGTDALRFGLCAYMSQGRDINLDVNRILGYRHFCNKLWNATKFA LRGLGKGFVPSPTSQPGGHESLVDRWIRSRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLY ELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMP QAPPSLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRIRPDCFLEVAD EATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVALASDRCSIHLQLQGLVDPARE LGKLQAKRVEAQRQAQRLRERRAASGYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALF QKML > DME ID: DME0182 DME Name: Hydroxyindole O-methyltransferase (ASMT) PDB ID: 4A6D; 4A6E MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK > DME ID: DME0183 DME Name: Methionine adenosyltransferase II beta (MAT2B) PDB ID: 2YDX; 2YDY; 4KTT; 4KTV; 4NDN MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH > DME ID: DME0184 DME Name: Methionine-R-sulfoxide reductase B1 (MSRB1) PDB ID: 3MAO MSFCSFFGGEVFQNHFEPGVYVCAKCGYELFSSRSKYAHSSPWPAFTETIHADSVAKRPE HNRSEALKVSCGKCGNGLGHEFLNDGPKPGQSRFUIFSSSLKFVPKGKETSASQGH > DME ID: DME0185 DME Name: Methionine-R-sulfoxide reductase B2 (MSRB2) PDB ID: Not Available MARLLWLLRGLTLGTAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTP EQFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTS GSDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPR KH > DME ID: DME0186 DME Name: Methionine-tRNA ligase cytoplasmic (MARS) PDB ID: 2DJV; 4BL7; 4BVX; 4BVY; 5GL7; 5GOY; 5Y6L MRLFVSDGVPGCLPVLAAAGRARGRAEVLISTVGPEDCVVPFLTRPKVPVLQLDSGNYLF STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGSVRRA LTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQTLSTQE PCQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAW EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL RQWNTLYLCGTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWFNISFDIFGRTTTP QQTKITQDIFQQLLKRGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK CGKLINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEEWLGRTLPGSDWTPNAQF ITRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW KNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV GVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFINRAGMF VSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ VNEPWKRIKGSEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI LLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQ QIQALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGKPPEAPKGKKKK > DME ID: DME0187 DME Name: Methionine-tRNA ligase mitochondrial (MARS2) PDB ID: Not Available MLRTSVLRLLGRTGASRLSLLEDFGPRYYSSGSLSAGDDACDVRAYFTTPIFYVNAAPHI GHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATAGLAPTELCDRVSEQ FQQLFQEAGISCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGVYEGWYCASDECFLPEA KVTQQPGPSGDSFPVSLESGHPVSWTKEENYIFRLSQFRKPLQRWLRGNPQAITPEPFHH VVLQWLDEELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVIGYPNAEFKSW WPATSHIIGKDILKFHAIYWPAFLLGAGMSPPQRICVHSHWTVCGQKMSKSLGNVVDPRT CLNRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLNSELADALGGLLNRCTAKRINPSET YPAFCTTCFPSEPGLVGPSVRAQAEDYALVSAVATLPKQVADHYDNFRIYKALEAVSSCV RQTNGFVQRHAPWKLNWESPVDAPWLGTVLHVALECLRVFGTLLQPVTPSLADKLLSRLG VSASERSLGELYFLPRFYGHPCPFEGRRLGPETGLLFPRLDQSRTWLVKAHRT > DME ID: DME0188 DME Name: Peptide methionine sulfoxide reductase (MSRA) PDB ID: Not Available MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP FPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVR VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK > DME ID: DME0189 DME Name: S-adenosylmethionine synthase 1 (MAT1A) PDB ID: 2OBV MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF > DME ID: DME0190 DME Name: S-adenosylmethionine synthase 2 (MAT2A) PDB ID: 4KTV; 4NDN; 5A19; 5A1G; 5A1I; 5UGH; 6FAJ; 6FBN; 6FBO MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY > DME ID: DME0191 DME Name: Folylpolyglutamate synthase (FPGS) PDB ID: Not Available MSRARSHLRAALFLAAASARGITTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGE HQRSNAALALQLAHCWLQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW PGRTQVLRRGPLTWYLDGAHTASSAQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRD PAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEE QASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSP PKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ > DME ID: DME0193 DME Name: Arylsulfatase A (ARSA) PDB ID: 1AUK; 1E1Z; 1E2S; 1E33; 1E3C; 1N2K; 1N2L; 2AIJ; 2HI8 MGAPRSLLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFT DFYVPVSLCTPSRAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGM AGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP LLANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAE RSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRC GKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSP LLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSL TAHEPPLLYDLSKDPGENYNLLGGVAGATPEVLQALKQLQLLKAQLDAAVTFGPSQVARG EDPALQICCHPGCTPRPACCHCPDPHA > DME ID: DME0194 DME Name: Choline phosphatase 1 (PLD1) PDB ID: Not Available MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGL KPHFKLFHPSSESEQGLTRPHADTGSIRSLQTGVGELHGETRFWHGKDYCNFVFKDWVQL DKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL PKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYHEESIHAAYVHVIENSRHYIYIE NQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGNALQ AIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRLQCF RVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLIQLRDFI NKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT > DME ID: DME0195 DME Name: Phosphodiesterase 5A (PDE5A) PDB ID: 1T9S; 1TBF; 1UDT; 1UDU; 1UHO; 1XOZ; 1XP0; 2CHM; 2H40 MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPL NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTME PLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE LVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN > DME ID: DME0197 DME Name: Aldo-keto reductase 1C1 (AKR1C1) PDB ID: 1MRQ; 3C3U; 3GUG; 3NTY; 4YVP; 6A7A; 6IJX MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN RNVRYLTLDIFAGPPNYPFSDEY > DME ID: DME0198 DME Name: Aldo-keto reductase 1C4 (AKR1C4) PDB ID: 2FVL MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN RNYRYVVMDFLMDHPDYPFSDEY > DME ID: DME0199 DME Name: Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) PDB ID: 2BEL; 2ILT; 2IRW; 2RBE; 3BYZ; 3BZU; 3CH6; 3CZR; 3D3E MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH VVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMV AAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEE CALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK > DME ID: DME0200 DME Name: Bile acid-CoA thioesterase (BAAT) PDB ID: Not Available MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDL NHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVAS APKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASL LASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQI GLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFE TTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGA GHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL > DME ID: DME0201 DME Name: Arachidonate 5-lipoxygenase (ALOX5) PDB ID: 2ABV; 3O8Y; 3V92; 3V98; 3V99 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY YYLSPDRIPNSVAI > DME ID: DME0202 DME Name: Fatty acid desaturase 1 (FADS1) PDB ID: Not Available MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVIS HYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVE RMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHD FGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFA LGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVIQRKKWVDLAWMI TFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQL QATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLL SAFADIIHSLKESGQLWLDAYLHQ > DME ID: DME0203 DME Name: Fatty acid desaturase 2 (FADS2) PDB ID: Not Available MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL RALLDIIRSLKKSGKLWLDAYLHK > DME ID: DME0204 DME Name: Steroid 5-alpha-reductase 1 (SRD5A1) PDB ID: Not Available MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY LRKFEEYPKFRKIIIPFLF > DME ID: DME0205 DME Name: UDP-glucuronosyltransferase 2B10 (UGT2B10) PDB ID: Not Available MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSAS ILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTFWLPFSQEQEILWAIND IIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFE RHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLG RPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGE NGVVVFSLGSMVSNMTEERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQND LLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMS STDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAH NLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFARKGKKGKRD > DME ID: DME0206 DME Name: Sodium/potassium-transporting ATPase gamma (FXYD2) PDB ID: 2MKV MTGLSMDGGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQ INEDEP > DME ID: DME0207 DME Name: Proline dehydrogenase 1 (PRODH) PDB ID: Not Available MALRRALPALRPCIPRFVQLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDFGNAQE AYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAG EDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQ YQAHRAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEASGRVSDDGFIAIKLTALGR PQFLLQFSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDW FTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRML QRMDVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEKPLIFNTYQCYLKDAY DNVTLDVELARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDY VLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADHQVYFGQLLGMCDQISFPLGQ AGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLRRLRTGNLFHRPA > DME ID: DME0208 DME Name: Oleamide hydrolase 1 (FAAH) PDB ID: Not Available MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS > DME ID: DME0209 DME Name: Pyridoxamine-phosphate oxidase (PNPO) PDB ID: 1NRG; 3HY8; 6H00 MTCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDREAFEETHLTSLDPVK QFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKE LDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPD REYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGD SPLGPMTHRGEEDWLYERLAP > DME ID: DME0210 DME Name: Thioredoxin reductase TR1 (TXNRD1) PDB ID: 1W1C; 2CFY; 2J3N; 2ZZ0; 2ZZB; 2ZZC; 3QFA; 3QFB MGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQ AYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAETDL PVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKE AAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKV EETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEK IYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLA GIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVV AQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIY AIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKA VEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQ GFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCUG > DME ID: DME0211 DME Name: Selenocysteine lyase (SCLY) PDB ID: 3GZC; 3GZD MEAAVAPGRDAPAPAASQPSGCGKHNSPERKVYMDYNATTPLEPEVIQAMTKAMWEAWGN PSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTS KGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDI LAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGK QRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTP MIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFPGTQRLPNTCN FSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQPSPVLLSYGVPFDVARNALRLSVGR STTRAEVDLVVQDLKQAVAQLEDQA > DME ID: DME0212 DME Name: Acetyl-CoA synthetase (ACSS2) PDB ID: Not Available MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISWNQGIDLWWHELMQEAGDEC EPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIG WITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFG DEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPG ATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTY FKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVV GHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSG KIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ > DME ID: DME0213 DME Name: Hydroxyacid-oxoacid transhydrogenase (ADHFE1) PDB ID: Not Available MAAAARARVAYLLRQLQRAACQCPTHSHTYSQAPGLSPSGKTTDYAFEMAVSNIRYGAAV TKEVGMDLKNMGAKNVCLMTDKNLSKLPPVQVAMDSLVKNGIPFTVYDNVRVEPTDSSFM EAIEFAQKGAFDAYVAVGGGSTMDTCKAANLYASSPHSDFLDYVSAPIGKGKPVSVPLKP LIAVPTTSGTGSETTGVAIFDYEHLKVKIGITSRAIKPTLGLIDPLHTLHMPARVVANSG FDVLCHALESYTTLPYHLRSPCPSNPITRPAYQGSNPISDIWAIHALRIVAKYLKRAVRN PDDLEARSHMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKMYKAKDYNVDHPLVPHGLS VVLTSPAVFTFTAQMFPERHLEMAEILGADTRTARIQDAGLVLADTLRKFLFDLDVDDGL AAVGYSKADIPALVKGTLPQERVTKLAPCPQSEEDLAALFEASMKLY > DME ID: DME0214 DME Name: Succinate-semialdehyde dehydrogenase (ALDH5A1) PDB ID: 2W8N; 2W8O; 2W8P; 2W8Q; 2W8R MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLR TDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKER SSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIH TPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALAL AELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSV KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAF AEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFF EPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWR VAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL > DME ID: DME0215 DME Name: Adenosine 5'-monophosphoramidase (HINT1) PDB ID: 1KPB; 1KPC; 1KPE; 1KPF; 3TW2; 4EQE; 4EQG; 4EQH; 4ZKL MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHI SQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQ MHWPPG > DME ID: DME0216 DME Name: Putrescine acetyltransferase (SSAT1) PDB ID: 2B3U; 2B3V; 2B4B; 2B4D; 2B5G; 2F5I; 2FXF; 2G3T; 2JEV MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVP KEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRC RCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE > DME ID: DME0218 DME Name: Steroid 5-alpha-reductase 2 (SRD5A2) PDB ID: Not Available MQVQCQQSPVLAGSATLVALGALALYVAKPSGYGKHTESLKPAATRLPARAAWFLQELPS FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVYSLLNRGRPYPAILILRGTAFCT GNGVLQGYYLIYCAEYPDGWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEISYRI PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE DYPKSRKALIPFIF > DME ID: DME0219 DME Name: Steroid 5-alpha-reductase 3 (SRD5A3) PDB ID: Not Available MAPWAEAEHSALNPLRAVWLTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEP SRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQF QGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLVYYVLVGLTVLSQ VPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCNH RIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYK SKFVSYPKHRKAFLPFLF > DME ID: DME0221 DME Name: Dihydrotestosterone oxidoreductase (HSD3B1) PDB ID: Not Available MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLE GDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTL YTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL VDRHKETLKSKTQ > DME ID: DME0222 DME Name: Beta-HSD adrenal and gonadal type (HSD3B2) PDB ID: Not Available MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV DRHKETLKSKTQ > DME ID: DME0223 DME Name: Hypoxanthine phosphoribosyltransferase (HPRT1) PDB ID: 1HMP; 1Z7G; 2VFA; 3GEP; 3GGC; 3GGJ; 4IJQ; 4KN6; 4RAB MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA > DME ID: DME0224 DME Name: HMG-CoA reductase (HMGCR) PDB ID: 1DQA; 1HW8; 1HW9; 1HWI; 1HWJ; 1HWK; 1HWL; 2Q1L; 2Q6B MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA > DME ID: DME0225 DME Name: Cytosolic phospholipase A2 (PLA2G4A) PDB ID: 1BCI; 1CJY; 1RLW MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRT RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEV PFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEG LHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSH PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG ETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEE LENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFN TREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDV KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN KLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETE EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRR QNPSRCSVSLSNVEARRFFNKEFLSKPKA > DME ID: DME0227 DME Name: Retinoic acid 4-hydroxylase 26A1 (CYP26A1) PDB ID: Not Available MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQM VLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTIL GSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPE VKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKAR NLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIEHSWERGERLDMQALKQSSTELLFG GHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVI KETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFM LPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTV YPVDNLPARFTHFHGEI > DME ID: DME0229 DME Name: Testicular acid phosphatase (ACP4) PDB ID: Not Available MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVAS TLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANL AGLFPEAAPGSPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALE GWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISAL DIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLALQGALG LYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLG RFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLR ALGGPV > DME ID: DME0230 DME Name: Tartrate-resistant acid ATPase (ACP5) PDB ID: 1WAR; 2BQ8 MDMWTALLILQALLLPSLADGATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQI LGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQ IAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKL ARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGH DHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSK EMTVTYIEASGKSLFKTRLPRRARP > DME ID: DME0231 DME Name: Acid phosphatase-like protein 1 (ACP6) PDB ID: 4JOB; 4JOC; 4JOD MITGVFSMRLWTPVGVLTSLAYCLHQRRVALAELQEADGQCPVDRSLLKLKMVQVVFRHG ARSPLKPLPLEEQVEWNPQLLEVPPQTQFDYTVTNLAGGPKPYSPYDSQYHETTLKGGMF AGQLTKVGMQQMFALGERLRKNYVEDIPFLSPTFNPQEVFIRSTNIFRNLESTRCLLAGL FQCQKEGPIIIHTDEADSEVLYPNYQSCWSLRQRTRGRRQTASLQPGISEDLKKVKDRMG IDSSDKVDFFILLDNVAAEQAHNLPSCPMLKRFARMIEQRAVDTSLYILPKEDRESLQMA VGPFLHILESNLLKAMDSATAPDKIRKLYLYAAHDVTFIPLLMTLGIFDHKWPPFAVDLT MELYQHLESKEWFVQLYYHGKEQVPRGCPDGLCPLDMFLNAMSVYTLSPEKYHALCSQTQ VMEVGNEE > DME ID: DME0232 DME Name: Prostatic acid phosphatase (ACP3) PDB ID: 1CVI; 1ND5; 1ND6; 2HPA; 2L3H; 2L77; 2L79; 2MG0; 3PPD MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL AALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSE LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV GPVIPQDWSTECMTTNSHQGTEDSTD > DME ID: DME0233 DME Name: Aldo-keto reductase 1C2 (AKR1C2) PDB ID: 1XJB; 2HDJ; 2IPJ; 4JQ1; 4JQ2; 4JQ3; 4JQ4; 4JQA; 4JTQ MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN RNVRYLTLDIFAGPPNYPFSDEY > DME ID: DME0234 DME Name: Succinic semialdehyde reductase (AKR7A2) PDB ID: 2BP1 MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAV RAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVR SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE ICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYE DKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMY HHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR > DME ID: DME0244 DME Name: Eosinophil peroxidase (EPX) PDB ID: Not Available MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE PQLRLLSQASGCALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLS LPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPE SPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRVRN QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCL LTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARK IMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPF MFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDEL RDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLAR KFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTK RQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT > DME ID: DME0246 DME Name: Lactoperoxidase (LPO) PDB ID: Not Available MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN > DME ID: DME0250 DME Name: Xylosyl phosphatase (PXYLP1) PDB ID: Not Available MLFRNRFLLLLALAALLAFVSLSLQFFHLIPVSTPKNGMSSKSRKRIMPDPVTEPPVTDP VYEALLYCNIPSVAERSMEGHAPHHFKLVSVHVFIRHGDRYPLYVIPKTKRPEIDCTLVA NRKPYHPKLEAFISHMSKGSGASFESPLNSLPLYPNHPLCEMGELTQTGVVQHLQNGQLL RDIYLKKHKLLPNDWSADQLYLETTGKSRTLQSGLALLYGFLPDFDWKKIYFRHQPSALF CSGSCYCPVRNQYLEKEQRRQYLLRLKNSQLEKTYGEMAKIVDVPTKQLRAANPIDSMLC HFCHNVSFPCTRNGCVDMEHFKVIKTHQIEDERERREKKLYFGYSLLGAHPILNQTIGRM QRATEGRKEELFALYSAHDVTLSPVLSALGLSEARFPRFAARLIFELWQDREKPSEHSVR ILYNGVDVTFHTSFCQDHHKRSPKPMCPLENLVRFVKRDMFVALGGSGTNYYDACHREGF > DME ID: DME0255 DME Name: Acyl-CoA thioesterase 2 (ACOT2) PDB ID: 3HLK MSNKLLSPHPHSVVLRSEFKMASSPAVLRASRLYQWSLKSSAQFLGSPQLRQVGQIIRVP ARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLG ELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGR LLCQTRHERYFLPPGVRREPVRVGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLL AGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELC LSMASFLKGITAAVVINGSVANVGGTLHYKGETLPPVGVNRNRIKVTKDGYADIVDVLNS PLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPET GHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIP SKV > DME ID: DME0263 DME Name: Peroxisomal multifunctional enzyme 2 (HSD17B4) PDB ID: 1IKT; 1S9C; 1ZBQ MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI MLSQKLQMILKDYAKL > DME ID: DME0283 DME Name: Dimethylaniline oxidase 2 (FMO2) PDB ID: Not Available MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVT NTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFS SSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPD GFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFR SMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVK STVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAH LDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRIDLF GESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSYQYRLVGPGQ WEGARNAIFTQKQRILKPLKTRALKDSSNFSVSFLLKILGLLAVVVAFFCQLQWS > DME ID: DME0286 DME Name: Aldehyde dehydrogenase 1 (ALDH1) PDB ID: 4WP7; 4WPN; 4X4L; 5AC2; 5L2M; 5L2N; 5L2O; 5TEI; 6DUM MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDV DKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYL NDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKI GPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDID KVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQG QCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIES GKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKR ANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGE YGFHEYTEVKTVTVKISQKNS > DME ID: DME0287 DME Name: Retinal dehydrogenase 2 (ALDH1A2) PDB ID: 4X2Q; 6ALJ; 6B5G; 6B5H; 6B5I MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNP ATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRAVL ATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVINILP GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD LDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG PQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ SPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS > DME ID: DME0289 DME Name: Aldehyde dehydrogenase 5 (ALDHX) PDB ID: Not Available MLRFLAPRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPT TGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVERDRVYLA SLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCG QIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITG YGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADM EHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGP QVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGP VQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHT PFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS > DME ID: DME0294 DME Name: Aldehyde dehydrogenase 7 (ALDH7) PDB ID: Not Available MDPLGDTLRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESE VSEVAISQGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNL TLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHR FDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNA GQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGC GRVAIGGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREK PLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFD TFSHHRACLLRSPGMEKLNALRYPPQSPRRLRMLLVAMEAQGCSCTLL > DME ID: DME0299 DME Name: Aminomuconic semialdehyde dehydrogenase (ALDH12) PDB ID: Not Available MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPS WSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASS SLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPS ELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERIT QLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIY SEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDK LSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLA ATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEI KTITVKH > DME ID: DME0308 DME Name: Glutathione S-transferase mu-1 (GSTM1) PDB ID: 1GTU; 1XW6; 1XWK; 1YJ6; 2F3M MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK > DME ID: DME0313 DME Name: Glutathione S-transferase omega-1 (GSTO1) PDB ID: 3VLN; 4IS0; 4YQM; 4YQU; 4YQV; 5UEH; 5V3Q; 5YVN; 5YVO MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG L > DME ID: DME0314 DME Name: Glutathione S-transferase omega-2 (GSTO2) PDB ID: 3Q18; 3Q19; 3QAG MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF GLC > DME ID: DME0326 DME Name: UDP-glucuronosyltransferase 2A3 (UGT2A3) PDB ID: Not Available MRSDKSALVFLLLQLFCVGCGFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSK PSLIDYRKPSALKFEVVHMPQDRTEENEIFVDLALNVLPGLSTWQSVIKLNDFFVEIRGT LKMMCESFIYNQTLMKKLQETNYDVMLIDPVIPCGDLMAELLAVPFVLTLRISVGGNMER SCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKALGR PTTLCETVGKAEIWLIRTYWDFEFPQPYQPNFEFVGGLHCKPAKALPKEMENFVQSSGED GIVVFSLGSLFQNVTEEKANIIASALAQIPQKVLWRYKGKKPSTLGANTRLYDWIPQNDL LGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTS EDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRSAAHD LTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNKTRKIEKRE > DME ID: DME0336 DME Name: Cysteinyl-conjugate N-acetyltransferase (NAT8) PDB ID: Not Available MAPCHIRKYQESDRQWVVGLLSRGMAEHAPATFRQLLKLPRTLILLLGGPLALLLVSGSW LLALVFSISLFPALWFLAKKPWTEYVDMTLCTDMSDITKSYLSERGSCFWVAESEEKVVG MVGALPVDDPTLREKRLQLFHLFVDSEHRRQGIAKALVRTVLQFARDQGYSEVILDTGTI QLSAMALYQSMGFKKTGQSFFCVWARLVALHTVHFIYHLPSSKVGSL > DME ID: DME0380 DME Name: Sulfotransferase 1B1 (SULT1B1) PDB ID: 2Z5F; 3CKL MLSPKDILRKDLKLVHGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSGTTWVSEIIDM ILNDGDIEKCKRGFITEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFW ENNCKMIYLARNAKDVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNW WKKKEEHPILFLYYEDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVN YTHLPTTVMDHSKSPFMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQFRTEI > DME ID: DME0383 DME Name: Sulfotransferase 1C4 (SULT1C4) PDB ID: 2AD1; 2GWH MALHDMEDFTFDGTKRLSVNYVKGILQPTDTCDIWDKIWNFQAKPDDLLISTYPKAGTTW TQEIVELIQNEGDVEKSKRAPTHQRFPFLEMKIPSLGSGLEQAHAMPSPRILKTHLPFHL LPPSLLEKNCKIIYVARNPKDNMVSYYHFQRMNKALPAPGTWEEYFETFLAGKVCWGSWH EHVKGWWEAKDKHRILYLFYEDMKKNPKHEIQKLAEFIGKKLDDKVLDKIVHYTSFDVMK QNPMANYSSIPAEIMDHSISPFMRKGAVGDWKKHFTVAQNERFDEDYKKKMTDTRLTFHF QF > DME ID: DME0384 DME Name: Sulfotransferase 2B1 (SULT2B1) PDB ID: 1Q1Q; 1Q1Z; 1Q20; 1Q22 MDGPAEPQIPGLWDTYEDDISEISQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRD DDIFIITYPKSGTTWMIEIICLILKEGDPSWIRSVPIWERAPWCETIVGAFSLPDQYSPR LMSSHLPIQIFTKAFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFL KGEVQFGSWFDHIKGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSV VAHSTFSAMKANTMSNYTLLPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQ MRGMPTFPWDEDPEEDGSPDPEPSPEPEPKPSLEPNTSLEREPRPNSSPSPSPGQASETP HPRPS > DME ID: DME0389 DME Name: Bifunctional epoxide hydrolase 2 (EPHX2) PDB ID: 1ZD2; 1ZD3; 1ZD4; 1ZD5; 3ANS; 3ANT; 3I1Y; 3I28; 3KOO MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK WLDSDARNPPVVSKM > DME ID: DME0398 DME Name: Small intestine reductase (AKR1B10) PDB ID: 4GAB; 4GQ0; 4GQG; 4I5X; 4ICC; 4JIH; 4JII; 4WEV; 4XZL MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN VLQSSHLEDYPFNAEY > DME ID: DME0399 DME Name: Farnesol dehydrogenase (AKR1B15) PDB ID: Not Available MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQ EKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD DFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKP VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD FKEFSHLEDFPFDAEY > DME ID: DME0400 DME Name: Aldo-keto reductase 1D1 (AKR1D1) PDB ID: 3BV7; 3CAQ; 3CAS; 3CAV; 3CMF; 3COT; 3DOP; 3G1R; 3UZW MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN EHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIE VPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLK DALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIE ALNKNVRFVELLMWRDHPEYPFHDEY > DME ID: DME0401 DME Name: Porphobilinogen synthase (ALAD) PDB ID: 1E51; 1PV8; 5HMS; 5HNR MQPQSVLHSGYFHPLLRAWQTATTTLNASNLIYPIFVTDVPDDIQPITSLPGVARYGVKR LEEMLRPLVEEGLRCVLIFGVPSRVPKDERGSAADSEESPAIEAIHLLRKTFPNLLVACD VCLCPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKE ALMAHGLGNRVSVMSYSAKFASCFYGPFRDAAKSSPAFGDRRCYQLPPGARGLALRAVDR DVREGADMLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHGAQAGAFDLKAAV LEAMTAFRRAGADIIITYYTPQLLQWLKEE > DME ID: DME0402 DME Name: Arachidonate 12-lipoxygenase (ALOX12B) PDB ID: Not Available MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGY IPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIR KIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGE GTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQ TPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMC HPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLY LPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEI FKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMR NPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRR SIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI > DME ID: DME0403 DME Name: Arachidonate 15-lipoxygenase (ALOX15) PDB ID: 2ABT MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPL LFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDP QGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAK GLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVV LRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPL VMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSH LLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMST GGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVS LHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQH ASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQ PVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSV AI > DME ID: DME0404 DME Name: Amiloride-sensitive amine oxidase (AOC1) PDB ID: 3HI7; 3HIG; 3HII; 3K5T; 3MPH MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV > DME ID: DME0405 DME Name: Copper amine oxidase (AOC3) PDB ID: 1PU4; 1US1; 2C10; 2Y73; 2Y74; 3ALA; 4BTW; 4BTX; 4BTY MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN > DME ID: DME0407 DME Name: Aquaporin adipose (AQP7) PDB ID: 6KXW; 6N1G; 6QZI; 6QZJ MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVL NKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQF LGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTG MLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIA GWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITV LPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF > DME ID: DME0408 DME Name: Arsenite methyltransferase (AS3MT) PDB ID: Not Available MAALRDAEIQKDVQTYYGQVLKRSADLQTNGCVTTARPVPKHIREALQNVHEEVALRYYG CGLVIPEHLENCWILDLGSGSGRDCYVLSQLVGEKGHVTGIDMTKGQVEVAEKYLDYHME KYGFQASNVTFIHGYIEKLGEAGIKNESHDIVVSNCVINLVPDKQQVLQEAYRVLKHGGE LYFSDVYTSLELPEEIRTHKVLWGECLGGALYWKELAVLAQKIGFCPPRLVTANLITIQN KELERVIGDCRFVSATFRLFKHSKTGPTKRCQVIYNGGITGHEKELMFDANFTFKEGEIV EVDEETAAILKNSRFAQDFLIRPIGEKLPTSGGCSALELKDIITDPFKLAEESDSMKSRC VPDAAGGCCGTKKSC > DME ID: DME0409 DME Name: Carbonic anhydrase II (CA2) PDB ID: 1AM6; 1AVN; 1BCD; 1BIC; 1BN1; 1BN3; 1BN4; 1BNM; 1BNN MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM VDNWRPAQPLKNRQIKASFK > DME ID: DME0410 DME Name: Serine sulfhydrase (CBS) PDB ID: 1JBQ; 1M54; 4COO; 4L0D; 4L28; 4L3V; 4PCU; 4UUU; 5MMS MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL NFVAAQERDQK > DME ID: DME0411 DME Name: Microsomal cytochrome MCB5 (CYB5A) PDB ID: 2I96 MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDAT ENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISA VAVALMYRLYMAED > DME ID: DME0412 DME Name: Dicarbonyl/L-xylulose reductase (DCXR) PDB ID: 1PR9; 1WNT; 3D3W MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG FWAC > DME ID: DME0413 DME Name: Delta(24)-sterol reductase (DHCR24) PDB ID: Not Available MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKL SSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMD ILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKY GLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKL RFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYY KPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVP PKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCPFILPSQ PGLVHPKGNEAELYIDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREE FWEMFDGSLYHKLREKLGCQDAFPEVYDKICKAARH > DME ID: DME0414 DME Name: Short-chain dehydrogenase/reductase retSDR1 (DHRS3) PDB ID: Not Available MVWKRLGALVMFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAE RGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITIL VNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALS AIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPP LKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTCMNTFKG RT > DME ID: DME0415 DME Name: Thymidylate kinase (DTYMK) PDB ID: 1E9E; 1E9F; 1NMX; 1NMY; 1NMZ; 1NN0; 1NN5; 2XX3 MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKK SDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQP DVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDA SKSIEAVHEDIRVLSEDAIRTATEKPLGELWK > DME ID: DME0416 DME Name: Friedreich ataxia protein (FXN) PDB ID: 3S4M; 3S5D; 3S5E; 3S5F; 3T3J; 3T3K; 3T3L; 3T3T; 3T3X MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQR GLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTF EDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGV SLHELLAAELTKALKTKLDLSSLAYSGKDA > DME ID: DME0417 DME Name: Galactose kinase (GALK1) PDB ID: 1WUU; 1YH7; 6GR2; 6Q3W; 6Q8Z; 6Q90; 6Q91; 6QJE MAALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELM TVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAA PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGM PCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRR RQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDY RAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASA APHAMRHIQEHYGGTATFYLSQAADGAKVLCL > DME ID: DME0418 DME Name: Glutamine synthetase (GLUL) PDB ID: 2OJW; 2QC8 MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEW NFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRI MDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHY RACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDP KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL TGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCL LNETGDEPFQYKN > DME ID: DME0419 DME Name: Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) PDB ID: Not Available MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALAV LAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPG AIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELS PVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVA LLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKDYI EHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGLRR RFLQAFFISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR > DME ID: DME0420 DME Name: Estradiol 17-beta-dehydrogenase 1 (HSD17B1) PDB ID: 1DHT; 1EQU; 1FDS; 1FDT; 1FDU; 1FDV; 1FDW; 1I5R; 1IOL MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG GAGPGAEDEAGRGAVGDPELGDPPAAPQ > DME ID: DME0421 DME Name: Ketoacyl-CoA reductase (HSD17B12) PDB ID: Not Available MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT GLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERS KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLA KIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKS TRAHYLKKTKKN > DME ID: DME0422 DME Name: Estradiol 17-beta-dehydrogenase 2 (HSD17B2) PDB ID: Not Available MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLIL FSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPG AEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL LMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVT MFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYI LAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYD YFAKRHFGQDKPMPRALRMPNYKKKAT > DME ID: DME0423 DME Name: Testicular 17-beta-hydroxysteroid dehydrogenase (HSD17B3) PDB ID: Not Available MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGI GKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKL AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLI LNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLN TNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYV AYLKLNTKVR > DME ID: DME0424 DME Name: Keto-steroid reductase (HSD17B7) PDB ID: Not Available MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIW TLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQ KMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL > DME ID: DME0425 DME Name: Methylsterol monooxygenase 1 (MSMO1) PDB ID: Not Available MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEA LYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFT EYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPF GMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNL IPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE > DME ID: DME0426 DME Name: Methylarsonite methyltransferase N6AMT1 (N6AMT1) PDB ID: 6H1D; 6H1E; 6K0X; 6KMR; 6KMS; 6PED MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLDALEAAAAELAGVEICLEVGSGSGVVS AFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVKGLLPRLTEKVDLLV FNPPYVVTPPQEVGSHGIEAAWAGGRNGREVMDRFFPLVPDLLSPRGLFYLVTIKENNPE EILKIMKTKGLQGTTALSRQAGQETLSVLKFTKS > DME ID: DME0427 DME Name: Mevalonate pyrophosphate decarboxylase (MPD) PDB ID: 3D4J MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDF TEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPT AAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKD SIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEM ARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKV AYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAM EPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA > DME ID: DME0428 DME Name: Uracil phosphoribosyltransferase (UPRT) PDB ID: Not Available MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSL PAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIR ELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNC GVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPI LSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTH FGQKYFGTD > DME ID: DME0429 DME Name: Prostaglandin reductase 1 (PTGR1) PDB ID: 1ZSV; 2Y05 MVRTKTWTLKKHFVGYPTNSDFELKTAELPPLKNGEVLLEALFLTVDPYMRVAAKRLKEG DTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLTEWPDTIPLSLALG TVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVA YLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICG AISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEGKIQYKE YIIEGFENMPAAFMGMLKGDNLGKTIVKA > DME ID: DME0430 DME Name: Tyrosine-protein phosphatase STS1/TULA2 (UBASH3B) PDB ID: 2CPW; 2E5K; 5VR6; 5W5G MAQYGHPSPLGMAAREELYSKVTPRRNRQQRPGTIKHGSALDVLLSMGFPRARAQKALAS TGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKA HNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKED SAEVLKKFAADFAAEAASKTEVHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGC DWVATIFSRDIRFANHETLQVIYPYTPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTS LTTGCSGLLPENYITKADECSTWIFHGSYSILNTSSSNSLTFGDGVLERRPYEDQGLGET TPLTIICQPMQPLRVNSQPGPQKRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLN MPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTIIDHVYCSPSLRCVQTAHN ILKGLQQENHLKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPISKL VVSESYDTYISRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQ MVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE > DME ID: DME0431 DME Name: Methionine synthase reductase (MTRR) PDB ID: 2QTL; 2QTZ MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTT GTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGA RHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLV KSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASL NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI SNTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHI PAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDA CACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTAT TEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPI IMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHG ILTHLKVSFSRDAPVGEEEAPAKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDV HDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS > DME ID: DME0432 DME Name: Gamma-glutamyltranspeptidase 5 (GGT5) PDB ID: Not Available MARGYGATVSLVLLGLGLALAVIVLAVVLSRHQAPCGPQAFAHAAVAADSKVCSDIGRAI LQQQGSPVDATIAALVCTSVVNPQSMGLGGGVIFTIYNVTTGKVEVINARETVPASHAPS LLDQCAQALPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLRGGHVVAPVL SRFLHNSILRPSLQASTLRQLFFNGTEPLRPQDPLPWPALATTLETVATEGVEVFYTGRL GQMLVEDIAKEGSQLTLQDLAKFQPEVVDALEVPLGDYTLYSPPPPAGGAILSFILNVLR GFNFSTESMARPEGRVNVYHHLVETLKFAKGQRWRLGDPRSHPKLQNASRDLLGETLAQL IRQQIDGRGDHQLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRT GIILNNELLDLCERCPRGSGTTPSPVSGDRVGGAPGRCWPPVPGERSPSSMVPSILINKA QGSKLVIGGAGGELIISAVAQAIMSKLWLGFDLRAAIAAPILHVNSKGCVEYEPNFSQEV QRGLQDRGQNQTQRPFFLNVVQAVSQEGACVYAVSDLRKSGEAAGY > DME ID: DME0437 DME Name: Purine nucleoside phosphorylase (PNP) PDB ID: 1PWY; 1RCT; 1RFG; 1RR6; 1RSZ; 1RT9; 1ULA; 1ULB; 1V2H MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS > DME ID: DME0438 DME Name: Phosphodiesterase 7B (PDE7B) PDB ID: 1LXW MSCLMVERCGEILFENPDQNAKCVCMLGDIRLRGQTGVRAERRGSYPFIDFRLLNSTTYS GEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIF LFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAAD VTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMS VLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHN KDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEIS PLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQ HRSRGSSGSGPDHDHAGQGTESEEQEGDSP > DME ID: DME0440 DME Name: VKORC1-like protein 1 (VKORC1L1) PDB ID: Not Available MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSA ALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMS VVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD > DME ID: DME0441 DME Name: ATP-AMP transphosphorylase 2 (AK2) PDB ID: 2C9Y MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI > DME ID: DME0442 DME Name: Dihydropyrimidinase-related protein 1 (DRP1) PDB ID: 4B3Z MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEA NGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSF EKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQ LYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAI TIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAA FVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEE RMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTI TAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQ RVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFS LSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG > DME ID: DME0443 DME Name: Deoxycytidine kinase (DCK) PDB ID: 1P61; 1P62; 2A2Z; 2A30; 2A7Q; 2NO0; 2NO1; 2NO6; 2NO7 MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCN VQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAE KPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQA TPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNE DFKDKYESLVEKVKEFLSTL > DME ID: DME0444 DME Name: Phospholipid phosphatase 1 (PLPP1) PDB ID: Not Available MFDKTRLPYVALDVLCVLLAGLPFAILTSRHTPFQRGVFCNDESIKYPYKEDTIPYALLG GIIIPFSIIVIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAK YSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCML FVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAI LVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP > DME ID: DME0445 DME Name: Nicotinamide N-methyltransferase (NNMT) PDB ID: 2IIP; 3ROD; 5YJF; 6B1A; 6CHH MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ SYSSTMANNEGLFSLVARKLSRPL > DME ID: DME0446 DME Name: Angiotensin-converting enzyme 2 (ACE2) PDB ID: 1XJP; 2AJF; 3D0G; 3D0H; 3D0I; 3KBH; 3SCI; 3SCJ; 3SCK MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQ NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTIL NTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQ AWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILM CTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKS IGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLH KCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNK NSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKN QMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDN SLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENP YASIDISKGENNPGFQNTDDVQTSF > DME ID: DME0447 DME Name: Acid cholesteryl ester hydrolase (LIPA) PDB ID: Not Available MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYI LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ > DME ID: DME0448 DME Name: Adenosine kinase (ADK) PDB ID: 1BX4; 2I6A; 2I6B; 4O1L MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD FH > DME ID: DME0450 DME Name: Gamma-glutamylcyclotransferase 2 (CHAC2) PDB ID: Not Available MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDPAGCV WGVAYRLPVGKEEEVKAYLDFREKGGYRTTTVIFYPKDPTTKPFSVLLYIGTCDNPDYLG PAPLEDIAEQIFNAAGPSGRNTEYLFELANSIRNLVPEEADEHLFALEKLVKERLEGKQN LNCI > DME ID: DME0451 DME Name: Thyroid peroxidase (TPO) PDB ID: Not Available MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL > DME ID: DME0452 DME Name: Phosphomannomutase 2 (PMM2) PDB ID: 2AMY; 2Q4R MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDV VEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFI EFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRI CELLFS > DME ID: DME0453 DME Name: Phosphomannomutase 1 (PMM1) PDB ID: 2FUC; 2FUE; 6CFR; 6CFS; 6CFT; 6CFU; 6CFV MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV VSPQDTVQRCREIFFPETAHEA > DME ID: DME0454 DME Name: Mevalonate kinase (MVK) PDB ID: 2R3V MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKR AWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSIC RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDM NQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQAL TSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL > DME ID: DME0455 DME Name: Sulfurylase kinase 1 (PAPSS1) PDB ID: 1X6V; 1XJQ; 1XNJ; 2OFW; 2OFX; 2PEY; 2PEZ; 2QJF MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGL SGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLF ADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAG EIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVP ENKLHLAKTDAETLPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGG VINLSVPIVLTATHEDKERLDGCTAFALMYEGRRVAILRNPEFFEHRKEERCARQWGTTC KNHPYIKMVMEQGDWLIGGDLQVLDRVYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQL RNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGV LNPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPS HGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQK PPEGFMAPKAWTVLTEYYKSLEKA > DME ID: DME0456 DME Name: Uridine/cytidine monophosphate kinase (UMPK) PDB ID: 1TEV MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEG KIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFF DCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKS VDEVFDEVVQIFDKEG > DME ID: DME0457 DME Name: Sucrase-isomaltase intestinal (SI) PDB ID: 3LPO; 3LPP MARKKFSGLEISLIVLFVIVTIIAIALIVVLATKTPAVDEISDSTSTPATTRVTTNPSDS GKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLIPWCFFVDNHGYNVQDMT TTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRFKITDPNNRRYEVPHQYVKEF TGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYG IGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSN AMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRW NYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQ KYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNP NCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMY SKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPNKRSFILTRSTFAGSGRHAAH WLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSR NHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHE FYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDAIWYDYESGAKRPWRKQRVDM YLPADKIGLHLRGGYIIPIQEPDVTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDT IQNGNYILYTFSVSNNTLDIVCTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMN AHSNFTYDASNQVLLIADLKLNLGRNFSVQWNQIFSENERFNCYPDADLATEQKCTQRGC VWRTGSSLSKAPECYFPRQDNSYSVNSARYSSMGITADLQLNTANARIKLPSDPISTLRV EVKYHKNDMLQFKIYDPQKKRYEVPVPLNIPTTPISTYEDRLYDVEIKENPFGIQIRRRS SGRVIWDSWLPGFAFNDQFIQISTRLPSEYIYGFGEVEHTAFKRDLNWNTWGMFTRDQPP GYKLNSYGFHPYYMALEEEGNAHGVFLLNSNAMDVTFQPTPALTYRTVGGILDFYMFLGP TPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTDI DYMERQLDFTIGEAFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQNDVF VKWPNTNDICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWAREIVD FYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFRTICMEA EQILSDGTSVLHYDVHNLYGWSQMKPTHDALQKTTGKRGIVISRSTYPTSGRWGGHWLGD NYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFYPYSRNHNI ANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLLHEFFDEKP TWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVPNARWFDYHTGKDIGVRGQFQTFNASYDT INLHVRGGHILPCQEPAQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDGESIDTYERDLY LSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTYNGNKNSLPFNE DTTNMILRIDLTTHNVTLEEPIEINWS > DME ID: DME0459 DME Name: Indoleamine 2,3-dioxygenase 2 (IDO2) PDB ID: Not Available MLHFHYYDTSNKIMEPHRPNVKTAVPLSLESYHISEEYGFLLPDSLKELPDHYRPWMEIA NKLPQLIDAHQLQAHVDKMPLLSCQFLKGHREQRLAHLVLSFLTMGYVWQEGEAQPAEVL PRNLALPFVEVSRNLGLPPILVHSDLVLTNWTKKDPDGFLEIGNLETIISFPGGESLHGF ILVTALVEKEAVPGIKALVQATNAILQPNQEALLQALQRLRLSIQDITKTLGQMHDYVDP DIFYAGIRIFLSGWKDNPAMPAGLMYEGVSQEPLKYSGGSAAQSTVLHAFDEFLGIRHSK ESGDFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCVQALAELRSYH ITMVTKYLITAAAKAKHGKPNHLPGPPQALKDRGTGGTAVMSFLKSVRDKTLESILHPRG > DME ID: DME0460 DME Name: Prolyl 4-hydroxylase alpha-2 (P4HA2) PDB ID: 6EVL; 6EVM; 6EVN; 6EVO; 6EVP MKLWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKS WANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQR QFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEG DYYHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSH ERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVK LTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPK LARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVAN YGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKK GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD > DME ID: DME0461 DME Name: Prolyl 4-hydroxylase alpha-1 (P4HA1) PDB ID: 1TJC; 2V5F; 2YQ8; 4BT8; 4BT9; 4BTA; 4BTB MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL RRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANY GVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE > DME ID: DME0462 DME Name: HIF-prolyl hydroxylase 2 (EGLN1) PDB ID: 2HBT; 2HBU; 2Y33; 2Y34; 3HQR; 3HQU; 3OUH; 3OUI; 3OUJ MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQG SEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADP AAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQL VSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMV ACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKF DRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDS VGKDVF > DME ID: DME0463 DME Name: Prolyl 4-hydroxylase alpha-3 (P4HA3) PDB ID: Not Available MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEA RLRDLTRFYDKVLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGY EKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLT GDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRA GNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDT YEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEA QKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRP PYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIY ANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSS SPED > DME ID: DME0464 DME Name: S-methyl-5'-thioadenosine phosphorylase (MTAP) PDB ID: 1K27; 1SD1; 1SD2; 3LN5; 3OZC; 3OZD; 3OZE; 5EUB; 5TC5 MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLAR HGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMR PQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTL KENANKAKSLLLTTIPQIGSTEWSETLHNLKNMAQFSVLLPRH > DME ID: DME0465 DME Name: UDP-glucose 6-dehydrogenase (UGDH) PDB ID: 2Q3E; 2QG4; 3ITK; 3KHU; 3PRJ; 4EDF; 5VR8; 6C58; 6C5A MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP KFSLQDPPNKKPKV > DME ID: DME0466 DME Name: Choline kinase alpha (CHKA) PDB ID: 2CKQ; 2I7Q; 3F2R; 3G15; 3ZM9; 4BR3; 4CG8; 4CG9; 4CGA MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV > DME ID: DME0467 DME Name: Choline/ethanolamine kinase (CHKB) PDB ID: 2IG7; 3FEG; 3LQ3 MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGA WRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLES VMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMP FTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCH NDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARP TDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQ ASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS > DME ID: DME0468 DME Name: NADPH:quinone reductase (CRYZ) PDB ID: 1YB5 MATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYS RKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEK LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTA GTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHG GRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIG SQYPLEKVAEAHENIIHGSGATGKMILLL > DME ID: DME0469 DME Name: GDP-D-glucose phosphorylase 1 (GDPGP1) PDB ID: Not Available MALPHDSNETSYLLPPNNEDWGRQTIPDFVYGQKDLMAEGIQWPRNAPGIPDALPQSPFD AALCSAWKQRVELGLFRYRLRELQTQILPGAVGFVAQLNVERGVQRRPPQTIKSVRQAFD PVQFNFNKIRPGEVLFRLHREPDLPGTLLQEDILVVINVSPLEWGHVLLVPEPARQLPQR LLPGALRAGIEAVLLSLHPGFRVGFNSLGGLASVNHLHLHGYYLAHRLPVEQAPSEPLDP GGHLHLLQDLPAPGFLFYTRGPGPDLESLISRVCRATDYLTDHEIAHNLFVTRGAPPGKT SPSSALTGVRVILWARKSSFGIKDGEAFNVALCELAGHLPVKTSQDFSSLTEAAAVALIQ DCRLPPSQAEDVQAALVALMSQEEQ > DME ID: DME0470 DME Name: Triokinase/FMN cyclase (TKFC) PDB ID: Not Available MTSKKLVNSVAGCADDALAGLVACNPNLQLLQGHRVALRSDLDSLKGRVALLSGGGSGHE PAHAGFIGKGMLTGVIAGAVFTSPAVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGL AREQARAEGIPVEMVVIGDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEAGVGLEEIAKQ VNVVAKAMGTLGVSLSSCSVPGSKPTFELSADEVELGLGIHGEAGVRRIKMATADEIVKL MLDHMTNTTNASHVPVQPGSSVVMMVNNLGGLSFLELGIIADATVRSLEGRGVKIARALV GTFMSALEMPGISLTLLLVDEPLLKLIDAETTAAAWPNVAAVSITGRKRSRVAPAEPQEA PDSTAAGGSASKRMALVLERVCSTLLGLEEHLNALDRAAGDGDCGTTHSRAARAIQEWLK EGPPPASPAQLLSKLSVLLLEKMGGSSGALYGLFLTAAAQPLKAKTSLPAWSAAMDAGLE AMQKYGKAAPGDRTMLDSLWAAGQELQAWKSPGADLLQVLTKAVKSAEAAAEATKNMEAG AGRASYISSARLEQPDPGAVAAAAILRAILEVLQS > DME ID: DME0471 DME Name: Hydroxyacyl-CoA dehydrogenase 2 (HSD17B10) PDB ID: 1F67; 1SO8; 1U7T; 2O23 MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI IENPFLNGEVIRLDGAIRMQP > DME ID: DME0472 DME Name: Retinol dehydrogenase 14 (RDH14) PDB ID: Not Available MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATA AELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLR SVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLK SSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNV TVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSG RYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK > DME ID: DME0473 DME Name: Diaphorase-1 (CYB5R3) PDB ID: 1M91; 1UMK MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRF RFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPK FPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAG GTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLD RAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFV F > DME ID: DME0474 DME Name: Retinol dehydrogenase 13 (RDH13) PDB ID: Not Available MSRYLLPLSALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELAR RGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDI LINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAG HIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRH TGIHGSTFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADVSGKYFDGLKQKAPAPEA EDEEVARRLWAESARLVGLEAPSVREQPLPR > DME ID: DME0475 DME Name: ADP-dependent glucokinase (ADPGK) PDB ID: Not Available MALWRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAA WDALIVRPVRRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSILHSRNDLEEAFI HFMGKGAAAERFFSDKETFHDIAQVASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGP VGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAM NMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELAS MTNRELMSSIVHQQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDILF WILKEHGRSKSRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETI DTSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLG DAISAEGLFYSEVHPHY > DME ID: DME0476 DME Name: Brain form hexokinase (HK1) PDB ID: 1CZA; 1DGK; 1HKB; 1HKC; 1QHA; 4F9O; 4FOI; 4FPA; 4FPB MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTAT VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT KDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRV LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVG TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDD IRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG AALITAVGVRLRTEASS > DME ID: DME0477 DME Name: Semicarbazide-sensitive amine oxidase (AOC2) PDB ID: Not Available MHLKIVLAFLALSLITIFALAYVLLTSPGGSSQPPHCPSVSHRAQPWPHPGQSQLFADLS REELTAVMRFLTQRLGPGLVDAAQAQPSDNCIFSVELQLPPKAAALAHLDRGSPPPAREA LAIVLFGGQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLRAEFTQMWRHLK EVELPKAPIFLSSTFNYNGSTLAAVHATPRGLRSGDRATWMALYHNISGVGLFLHPVGLE LLLDHRALDPAHWTVQQVFYLGHYYADLGQLEREFKSGRLEVVRVPLPPPNGASSLRSRN SPGPLPPLQFSPQGSQYSVQGNLVVSSLWSFTFGHGVFSGLRIFDVRFQGERIAYEVSVQ ECVSIYGADSPKTMLTRYLDSSFGLGRNSRGLVRGVDCPYQATMVDIHILVGKGAVQLLP GAVCVFEEAQGLPLRRHHNYLQNHFYGGLASSALVVRSVSSVGNYDYIWDFVLYPNGALE GRVHATGYINTAFLKGGEEGLLFGNRVGERVLGTVHTHAFHFKLDLDVAGLKNWVVAEDV VFKPVAAPWNPEHWLQRPQLTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAWGHQRGYR IQIHSPLGIHIPLESDMERALSWGRYQLVVTQRKEEESQSSSIYHQNDIWTPTVTFADFI NNETLLGEDLVAWVTASFLHIPHAEDIPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVY FEKGQDAGLCSINPVACLPDLAACVPDLPPFSYHGF > DME ID: DME0478 DME Name: Nicotinamide riboside kinase 2 (NRK2) PDB ID: Not Available MKLIVGIGGMTNGGKTTLTNSLLRALPNCCVIHQDDFFKPQDQIAVGEDGFKQWDVLESL DMEAMLDTVQAWLSSPQKFARAHGVSVQPEASDTHILLLEGFLLYSYKPLVDLYSRRYFL TVPYEECKWRRSTRNYTVPDPPGLFDGHVWPMYQKYRQEMEANGVEVVYLDGMKSREELF REVLEDIQNSLLNRSQESAPSPARPARTQGPGRGCGHRTARPAASQQDSM > DME ID: DME0479 DME Name: Nicotinamide riboside kinase 1 (NRK1) PDB ID: 2P0E; 2QG6; 2QL6; 2QSY; 2QSZ; 2QT0; 2QT1 MKTFIIGISGVTNSGKTTLAKNLQKHLPNCSVISQDDFFKPESEIETDKNGFLQYDVLEA LNMEKMMSAISCWMESARHSVVSTDQESAEEIPILIIEGFLLFNYKPLDTIWNRSYFLTI PYEECKRRRSTRVYQPPDSPGYFDGHVWPMYLKYRQEMQDITWEVVYLDGTKSEEDLFLQ VYEDLIQELAKQKCLQVTA > DME ID: DME0480 DME Name: Uridine-cytidine kinase 2 (UCK2) PDB ID: 1UDW; 1UEI; 1UEJ; 1UFQ; 1UJ2; 1XRJ; 6N53; 6N54; 6N55 MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILS QDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRK EETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQ ILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGPSKRQTNG CLNGYTPSRKRQASESSSRPH > DME ID: DME0481 DME Name: Uridine-cytidine kinase 1 (UCK1) PDB ID: 2JEO; 2UVQ MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVV ILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTH SRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDL EQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHR GGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH > DME ID: DME0482 DME Name: Cytosolic 5'-nucleotidase II (NT5C2) PDB ID: 2JCM; 2XCV; 2XCW; 2XCX; 2XJB; 2XJC; 2XJD; 2XJE; 2XJF MSTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVY KSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLV CAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTS CETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMK EVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGT VLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKS KKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQ RRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAA HVLMPHESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLA PQEITHCHDEDDDEEEEEEEE > DME ID: DME0483 DME Name: Sphingosine kinase 2 (SPHK2) PDB ID: Not Available MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPPPLAASTPLLHGEFGSYPA RGPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTY PRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRP PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDG IVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDL LLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTL GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSV SDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKA ALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPPDWVTLEGDFVL MLAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQL GYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP > DME ID: DME0484 DME Name: Sphingosine kinase 1 (SPHK1) PDB ID: 3VZB; 3VZC; 3VZD; 4L02; 4V24 MDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHA RELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASL NHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLE SEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVP LEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLL RLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFW MVSGCVEPPPSWKPQQMPPPEEPL > DME ID: DME0485 DME Name: Glutamate-cysteine ligase catalytic (GCLC) PDB ID: Not Available MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH ENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV EANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFTEDDEASRASKPDHIYMDA MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL QGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS LILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN > DME ID: DME0486 DME Name: Glutamate-cysteine ligase regulatory (GCLM) PDB ID: Not Available MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINP DLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAH EWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS > DME ID: DME0487 DME Name: Delta-aminolevulinate synthase 2 (ALAS2) PDB ID: 5QQS; 5QQT; 5QQU; 5QQV; 5QQW; 5QQX; 5QQY; 5QQZ; 5QR0 MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA > DME ID: DME0488 DME Name: Carnosine N-methyltransferase (CARNMT1) PDB ID: 5YF0; 5YF1; 5YF2 MQRRRRPPPPTSRLPEGCGGGGGGSEEVEVQFSAGRWGSAAAVSAAAAAATRSTEEEEER LEREHFWKIINAFRYYGTSMHERVNRTERQFRSLPANQQKLLPQFLLHLDKIRKCIDHNQ EILLTIVNDCIHMFENKEYGEDGNGKIMPASTFDMDKLKSTLKQFVRDWSETGKAERDAC YQPIIKEILKNFPKERWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNF VLNRCSEINKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGSNFSMTAGDFQEIY SECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINLGPLLYHFENLANELSIELS YEDIKNVVLQYGFKVEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ > DME ID: DME0489 DME Name: Liver-type arginase (ARG1) PDB ID: 2AEB; 2PHA; 2PHO; 2PLL; 2ZAV; 3DJ8; 3E6K; 3E6V; 3F80 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT LACFGLAREGNHKPIDYLNPPK > DME ID: DME0490 DME Name: Chondroitin sulfate glucuronyltransferase (CHPF2) PDB ID: Not Available MRLSSLLALLRPALPLILGLSLGCSLSLLRVSWIQGEGEDPCVEAVGERGGPQNPDSRAR LDQSDEDFKPRIVPYYRDPNKPYKKVLRTRYIQTELGSRERLLVAVLTSRATLSTLAVAV NRTVAHHFPRLLYFTGQRGARAPAGMQVVSHGDERPAWLMSETLRHLHTHFGADYDWFFI MQDDTYVQAPRLAALAGHLSINQDLYLGRAEEFIGAGEQARYCHGGFGYLLSRSLLLRLR PHLDGCRGDILSARPDEWLGRCLIDSLGVGCVSQHQGQQYRSFELAKNRDPEKEGSSAFL SAFAVHPVSEGTLMYRLHKRFSALELERAYSEIEQLQAQIRNLTVLTPEGEAGLSWPVGL PAPFTPHSRFEVLGWDYFTEQHTFSCADGAPKCPLQGASRADVGDALETALEQLNRRYQP RLRFQKQRLLNGYRRFDPARGMEYTLDLLLECVTQRGHRRALARRVSLLRPLSRVEILPM PYVTEATRVQLVLPLLVAEAAAAPAFLEAFAANVLEPREHALLTLLLVYGPREGGRGAPD PFLGVKAAAAELERRYPGTRLAWLAVRAEAPSQVRLMDVVSKKHPVDTLFFLTTVWTRPG PEVLNRCRMNAISGWQAFFPVHFQEFNPALSPQRSPPGPPGAGPDPPSPPGADPSRGAPI GGRFDRQASAEGCFYNADYLAARARLAGELAGQEEEEALEGLEVMDVFLRFSGLHLFRAV EPGLVQKFSLRDCSPRLSEELYHRCRLSNLEGLGGRAQLAMALFEQEQANST > DME ID: DME0491 DME Name: Phenylalanine--tRNA ligase mitochondrial (FARS2) PDB ID: 3CMQ; 3HFV; 3TEG; 3TUP; 5MGH; 5MGU; 5MGV; 5MGW MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQ DDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVV TTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRR DQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVE FDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVN SAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKY PAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRH MERTLSQREVRHIHQALQEAAVQLLGVEGRF > DME ID: DME0492 DME Name: Nicotinate-nucleotide adenylyltransferase 3 (NMNAT3) PDB ID: 1NUP; 1NUQ; 1NUR; 1NUS; 1NUT; 1NUU MKSRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVNDTYGKKDLAA SHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKAL FSTPAAVPELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESP ILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGSTWK GKSTQSTEGKTS > DME ID: DME0493 DME Name: Nicotinate-nucleotide adenylyltransferase 1 (NMNAT1) PDB ID: 1GZU; 1KKU; 1KQN; 1KQO; 1KR2 MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGL IPAYHRVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLEASDCDHQQNSPTL ERPGRKRKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLLESFAVPNLWKSEDITQIVAN YGLICVTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIANDISSTKIRRALRRGQSIRYLV PDLVQEYIEKHNLYSSESEDRNAGVILAPLQRNTAEAKT > DME ID: DME0494 DME Name: Insulin-degrading enzyme (IDE) PDB ID: 2G49; 2G54; 2G56; 2JBU; 2JG4; 2WBY; 2WC0; 2WK3; 2YPU MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE LLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL > DME ID: DME0495 DME Name: Tyrosine-protein phosphatase non-receptor 1 (PTP1B) PDB ID: 1WAX; 1XBO; 2AZR; 2B07; 3ZMQ; 4I8N; 5QGF; 6B8E; 6B8T MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLH QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLK CAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWP DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKD PSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLE PPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYG IESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLT AGAYLCYRFLFNSNT > DME ID: DME0496 DME Name: Phosphoenolpyruvate carboxykinase (PCK1) PDB ID: 1KHB; 1KHE; 1KHF; 1KHG; 1M51; 1NHX; 2GMV MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQM EEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEE DFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPV LEAVGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSL LGKKCFALRMASRLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSL PGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNV AETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAW ESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPF AMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWM FNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQV NADLPCEIEREILALKQRISQM > DME ID: DME0497 DME Name: Red cell/liver pyruvate kinase (PKLR) PDB ID: 2VGB; 2VGF; 2VGG; 4IMA; 4IP7; 6NN4; 6NN5; 6NN7; 6NN8 MSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ LPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS HGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKG SQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQV ENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAA LGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKM QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRS AQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESG KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS > DME ID: DME0498 DME Name: Gamma-glutamyltranspeptidase 1 (GGT1) PDB ID: 4GDX; 4GG2; 4Z9O; 4ZBK; 4ZC6; 4ZCG; 5V4Q MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRD GGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFN SSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALEN KRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKD IQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSR ESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISD DTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNE MDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTA TALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTF IAVVQAIVRTAGGWAAASDSRKGGEPAGY > DME ID: DME0499 DME Name: Leucyl-tRNA synthetase (LARS2) PDB ID: Not Available MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVE KWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGM QVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPD YYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQ WFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYT ATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVI LAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQ DAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVT LPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPH SPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIK GQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGID TIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNK EKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDA LCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQ MAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFL VQD > DME ID: DME0500 DME Name: Arginine carboxypeptidase (CPN1) PDB ID: 2NSM MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA > DME ID: DME0501 DME Name: Soluble aminopeptidase P (sAmp) PDB ID: 3CTZ MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA GTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD PLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKD KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD RIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSE TIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI SAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQY KDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV LVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL QKQGRQEALEWLIRETQPISKQH > DME ID: DME0502 DME Name: Pantothenate kinase 3 (PANK3) PDB ID: 2I7P; 3MK6; 3SMS; 5KPR; 5KPT; 5KPZ; 5KQ8; 5KQD; 6B3V MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGS TGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYK FEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLD DPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASK GDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNN IGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAV GALLGLPNFS > DME ID: DME0503 DME Name: Lactate dehydrogenase C (LDHC) PDB ID: Not Available MSTVKEQLIEKLIEDDENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKG EMMDLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSI IPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGV HPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAYE IIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGV SDVVKINLNSEEEALFKKSAETLWNIQKDLIF > DME ID: DME0504 DME Name: NADP-dependent malic enzyme (ME1) PDB ID: 2AW5; 3WJA MEPEAPRRRHTHQRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVK NFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKP RGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTAC GGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGMNC LIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQ GAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEE MKNLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQC YKITKGRAIFASGSPFDPVTLPNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLT TAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATVYPEPQNKEAFV RSQMYSTDYDQILPDCYSWPEEVQKIQTKVDQ > DME ID: DME0505 DME Name: Inositol polyphosphate multikinase (IPMK) PDB ID: 5W2I; 6E7F; 6M88; 6M89; 6M8A; 6M8B; 6M8C; 6M8D; 6M8E MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK DKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPP TAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLG MRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWF ENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSS TANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLS QLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN > DME ID: DME0506 DME Name: Factor inhibiting HIF-1 (HIF1AN) PDB ID: 1H2M; 1H2N; 1IZ3; 1MZE; 1MZF; 1YCI; 2CGN; 2CGO; 2ILM MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN > DME ID: DME0507 DME Name: HIF-prolyl hydroxylase 3 (EGLN3) PDB ID: Not Available MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQ LAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKA MVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEP IFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED > DME ID: DME0508 DME Name: Prolyl 3-hydroxylase 1 (P3H1) PDB ID: Not Available MAVRALKLLTTLLAVVAAASQAEVESEAGWGMVTPDLLFAEGTAAYARGDWPGVVLSMER ALRSRAALRALRLRCRTQCAADFPWELDPDWSPSPAQASGAAALRDLSFFGGLLRRAACL RRCLGPPAAHSLSEEMELEFRKRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMQ QNLDYYQTMSGVKEADFKDLETQPHMQEFRLGVRLYSEEQPQEAVPHLEAALQEYFVAYE ECRALCEGPYDYDGYNYLEYNADLFQAITDHYIQVLNCKQNCVTELASHPSREKPFEDFL PSHYNYLQFAYYNIGNYTQAVECAKTYLLFFPNDEVMNQNLAYYAAMLGEEHTRSIGPRE SAKEYRQRSLLEKELLFFAYDVFGIPFVDPDSWTPEEVIPKRLQEKQKSERETAVRISQE IGNLMKEIETLVEEKTKESLDVSRLTREGGPLLYEGISLTMNSKLLNGSQRVVMDGVISD HECQELQRLTNVAATSGDGYRGQTSPHTPNEKFYGVTVFKALKLGQEGKVPLQSAHLYYN VTEKVRRIMESYFRLDTPLYFSYSHLVCRTAIEEVQAERKDDSHPVHVDNCILNAETLVC VKEPPAYTFRDYSAILYLNGDFDGGNFYFTELDAKTVTAEVQPQCGRAVGFSSGTENPHG VKAVTRGQRCAIALWFTLDPRHSERDRVQADDLVKMLFSPEEMDLSQEQPLDAQQGPPEP AQESLSGSESKPKDEL > DME ID: DME0509 DME Name: Prolyl 3-hydroxylase 2 (P3H2) PDB ID: Not Available MRERIWAPPLLLLLPLLLPPPLWGGPPDSPRRELELEPGPLQPFDLLYASGAAAYYSGDY ERAVRDLEAALRSHRRLREIRTRCARHCAARHPLPPPPPGEGPGAELPLFRSLLGRARCY RSCETQRLGGPASRHRVSEDVRSDFQRRVPYNYLQRAYIKLNQLEKAVEAAHTFFVANPE HMEMQQNIENYRATAGVEALQLVDREAKPHMESYNAGVKHYEADDFEMAIRHFEQALREY FVEDTECRTLCEGPQRFEEYEYLGYKAGLYEAIADHYMQVLVCQHECVRELATRPGRLSP IENFLPLHYDYLQFAYYRVGEYVKALECAKAYLLCHPDDEDVLDNVDYYESLLDDSIDPA SIEAREDLTMFVKRHKLESELIKSAAEGLGFSYTEPNYWIRYGGRQDENRVPSGVNVEGA EVHGFSMGKKLSPKIDRDLREGGPLLYENITFVYNSEQLNGTQRVLLDNVLSEEQCRELH SVASGIMLVGDGYRGKTSPHTPNEKFEGATVLKALKSGYEGRVPLKSARLFYDISEKARR IVESYFMLNSTLYFSYTHMVCRTALSGQQDRRNDLSHPIHADNCLLDPEANECWKEPPAY TFRDYSALLYMNDDFEGGEFIFTEMDAKTVTASIKPKCGRMISFSSGGENPHGVKAVTKG KRCAVALWFTLDPLYRELERIQADEVIAILDQEQQGKHELNINPKDEL > DME ID: DME0510 DME Name: Telethon sulfatase (ARSK) PDB ID: Not Available MLLLWVSVVAALALAVLAPGAGEQRRRAAKAPNVVLVVSDSFDGRLTFHPGSQVVKLPFI NFMKTRGTSFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNFKGLDPNYTTWMDVMERHG YRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVNLIRNRTKVRVMERDWQNT DKAVNWLRKEAINYTEPFVIYLGLNLPHPYPSPSSGENFGSSTFHTSLYWLEKVSHDAIK IPKWSPLSEMHPVDYYSSYTKNCTGRFTKKEIKNIRAFYYAMCAETDAMLGEIILALHQL DLLQKTIVIYSSDHGELAMEHRQFYKMSMYEASAHVPLLMMGPGIKAGLQVSNVVSLVDI YPTMLDIAGIPLPQNLSGYSLLPLSSETFKNEHKVKNLHPPWILSEFHGCNVNASTYMLR TNHWKYIAYSDGASILPQLFDLSSDPDELTNVAVKFPEITYSLDQKLHSIINYPKVSASV HQYNKEQFIKWKQSIGQNYSNVIANLRWHQDWQKEPRKYENAIDQWLKTHMNPRAV > DME ID: DME0511 DME Name: Lysosomal beta A mannosidase (MANBA) PDB ID: Not Available MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQD SYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETD NMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNF VRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFD VVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPA DSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACA LYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKD YVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDC WNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLN DIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSV RVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHE LLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFS DNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY > DME ID: DME0512 DME Name: Dinucleosidetriphosphatase (FHIT) PDB ID: Not Available MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQ TTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKH DKEDFPASWRSEEEMAAEAAALRVYFQ > DME ID: DME0513 DME Name: Galactose mutarotase (GALM) PDB ID: 1SNZ; 1SO0 MASVTRAVFGELPSGGGTVEKFQLQSDLLRVDIISWGCTITALEVKDRQGRASDVVLGFA ELEGYLQKQPYFGAVIGRVANRIAKGTFKVDGKEYHLAINKEPNSLHGGVRGFDKVLWTP RVLSNGVQFSRISPDGEEGYPGELKVWVTYTLDGGELIVNYRAQASQATPVNLTNHSYFN LAGQASPNINDHEVTIEADTYLPVDETLIPTGEVAPVQGTAFDLRKPVELGKHLQDFHLN GFDHNFCLKGSKEKHFCARVHHAASGRVLEVYTTQPGVQFYTGNFLDGTLKGKNGAVYPK HSGFCLETQNWPDAVNQPRFPPVLLRPGEEYDHTTWFKFSVA > DME ID: DME0514 DME Name: UDP-glucose pyrophosphorylase (UGPase) PDB ID: 3R2W; 3R3I; 4R7P MSRFVQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRK LFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTS MGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNH CRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFI GEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEG KLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLD GGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSE KREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIA NHGDRIDIPPGAVLENKIVSGNLRILDH > DME ID: DME0515 DME Name: PFK/FBPase 3 (PFKFB3) PDB ID: 2DWP; 2I1V; 3QPU; 3QPV; 3QPW; 4D4J; 4D4K; 4D4L; 4D4M MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH > DME ID: DME0516 DME Name: Acyl-CoA thioesterase 13 (ACOT13) PDB ID: 2F0X; 2H4U; 3F5O MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLT ATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDL TNKATGKLIAQGRHTKHLGN > DME ID: DME0517 DME Name: CDP-choline phosphohydrolase (ADPRM) PDB ID: Not Available MDDKPNPEALSDSSERLFSFGVIADVQFADLEDGFNFQGTRRRYYRHSLLHLQGAIEDWN NESSMPCCVLQLGDIIDGYNAQYNASKKSLELVMDMFKRLKVPVHHTWGNHEFYNFSREY LTHSKLNTKFLEDQIVHHPETMPSEDYYAYHFVPFPKFRFILLDAYDLSVLGVDQSSPKY EQCMKILREHNPNTELNSPQGLSEPQFVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIVS HLPIYPDASDNVCLAWNYRDALAVIWSHECVVCFFAGHTHDGGYSEDPFGVYHVNLEGVI ETAPDSQAFGTVHVYPDKMMLKGRGRVPDRIMNYKKERAFHC > DME ID: DME0518 DME Name: ASM-like phosphodiesterase 3a (SMPDL3A) PDB ID: 5EBB; 5EBE MALVRALVCCLLTAWHCRSGLGLPVAPAGGRNPPPAIGQFWHVTDLHLDPTYHITDDHTK VCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPEL STDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLD EEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNS QQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIM VLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEA NLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTC DKTCKAFQICAIMNLDNISYADCLKQLYIKHNY > DME ID: DME0521 DME Name: Glucosamine-6-phosphate deaminase 1 (GNPDA1) PDB ID: 1NE7 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD > DME ID: DME0522 DME Name: Glucosamine-6-phosphate deaminase 2 (GNPDA2) PDB ID: Not Available MRLVILDNYDLASEWAAKYICNRIIQFKPGQDRYFTLGLPTGSTPLGCYKKLIEYHKNGH LSFKYVKTFNMDEYVGLPRNHPESYHSYMWNNFFKHIDIDPNNAHILDGNAADLQAECDA FENKIKEAGGIDLFVGGIGPDGHIAFNEPGSSLVSRTRLKTLAMDTILANAKYFDGDLSK VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTIFVCD EDATLELRVKTVKYFKGLMHVHNKLVDPLFSMKDGN > DME ID: DME0523 DME Name: Glucose-6-phosphatase beta (G6PC3) PDB ID: Not Available MESTLGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRRVGIAVLWI SLITEWLNLIFKWFLFGDRPFWWVHESGYYSQAPAQVHQFPSSCETGPGSPSGHCMITGA ALWPIMTALSSQVATRARSRWVRVMPSLAYCTFLLAVGLSRIFILAHFPHQVLAGLITGA VLGWLMTPRVPMERELSFYGLTALALMLGTSLIYWTLFTLGLDLSWSISLAFKWCERPEW IHVDSRPFASLSRDSGAALGLGIALHSPCYAQVRRAQLGNGQKIACLVLAMGLLGPLDWL GHPPQISLFYIFNFLKYTLWPCLVLALVPWAVHMFSAQEAPPIHSS > DME ID: DME0524 DME Name: Inositol tetrakisphosphate 3-phosphatase (MIPP) PDB ID: Not Available MLRAPGCLLRTSVAPAAALAAALLSSLARCSLLEPRDPVASSLSPYFGTKTRYEDVNPVL LSGPEAPWRDPELLEGTCTPVQLVALIRHGTRYPTVKQIRKLRQLHGLLQARGSRDGGAS STGSRDLGAALADWPLWYADWMDGQLVEKGRQDMRQLALRLASLFPALFSRENYGRLRLI TSSKHRCMDSSAAFLQGLWQHYHPGLPPPDVADMEFGPPTVNDKLMRFFDHCEKFLTEVE KNATALYHVEAFKTGPEMQNILKKVAATLQVPVNDLNADLIQVAFFTCSFDLAIKGVKSP WCDVFDIDDAKVLEYLNDLKQYWKRGYGYTINSRSSCTLFQDIFQHLDKAVEQKQRSQPI SSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNYKKQMHRKFRSGLIVPYASNLIFVLY HCENAKTPKEQFRVQMLLNEKVLPLAYSQETVSFYEDLKNHYKDILQSCQTSEECELARA NSTSDEL > DME ID: DME0525 DME Name: Inositol polyphosphate 4-phosphatase I (INPP4A) PDB ID: Not Available MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA FPKHYRPPEGTYGKVET > DME ID: DME0526 DME Name: Xylulose kinase (XYLB) PDB ID: 4BC2; 4BC3; 4BC4; 4BC5 MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLT VTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSPDLR LHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIY QQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPH LEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLG TSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSK ALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVEVRALIEGQFMAKR IHAEGLGYRVMSKTKILATGGASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHG LAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQRILSQTRGPPE > DME ID: DME0527 DME Name: Fucosyltransferase XI (FUT11) PDB ID: Not Available MAAGPIRVVLVLLGVLSVCAASGHGSVAEREAGGEAEWAEPWDGAVFRPPSALGAVGVTR SSGTPRPGREEAGDLPVLLWWSPGLFPHFPGDSERIECARGACVASRNRRALRDSRTRAL LFYGTDFRASAAPLPRLAHQSWALLHEESPLNNFLLSHGPGIRLFNLTSTFSRHSDYPLS LQWLPGTAYLRRPVPPPMERAEWRRRGYAPLLYLQSHCDVPADRDRYVRELMRHIPVDSY GKCLQNRELPTARLQDTATATTEDPELLAFLSRYKFHLALENAICNDYMTEKLWRPMHLG AVPVYRGSPSVRDWMPNNHSVILIDDFESPQKLAEFIDFLDKNDEEYMKYLAYKQPGGIT NQFLLDSLKHREWGVNDPLLPNYLNGFECFVCDYELARLDAEKAHAASPGDSPVFEPHIA QPSHMDCPVPTPGFGNVEEIPENDSWKEMWLQDYWQGLDQGEALTAMIHNNETEQTKFWD YLHEIFMKRQHL > DME ID: DME0528 DME Name: Fucosyltransferase X (FUT10) PDB ID: Not Available MVRIQRRKLLASCLCVTATVFLLVTLQVMVELGKFERKEFKSSSLQDGHTKMEEAPTHLN SFLKKEGLTFNRKRKWELDSYPIMLWWSPLTGETGRLGQCGADACFFTINRTYLHHHMTK AFLFYGTDFNIDSLPLPRKAHHDWAVFHEESPKNNYKLFHKPVITLFNYTATFSRHSHLP LTTQYLESIEVLKSLRYLVPLQSKNKLRKRLAPLVYVQSDCDPPSDRDSYVRELMTYIEV DSYGECLRNKDLPQQLKNPASMDADGFYRIIAQYKFILAFENAVCDDYITEKFWRPLKLG VVPVYYGSPSITDWLPSNKSAILVSEFSHPRELASYIRRLDSDDRLYEAYVEWKLKGEIS NQRLLTALRERKWGVQDVNQDNYIDAFECMVCTKVWANIRLQEKGLPPKRWEAEDTHLSC PEPTVFAFSPLRTPPLSSLREMWISSFEQSKKEAQALRWLVDRNQNFSSQEFWGLVFKD > DME ID: DME0529 DME Name: GDP-mannose 4,6-dehydratase (GMDS) PDB ID: 1T2A; 5IN4; 5IN5; 6GPJ; 6GPK; 6GPL; 6Q94 MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSF NTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDL AEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYG AAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSL GNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEG KNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQGDCTKAKQKLNWKPRVAFDELVREMVH ADVELMRTNPNA > DME ID: DME0530 DME Name: Choline glycerophosphodiester phosphodiesterase (ENPP6) PDB ID: Not Available MAVKLGTLLLALALGLAQPASARRKLLVFLLDGFRSDYISDEALESLPGFKEIVSRGVKV DYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGS EPLWVTLTKAKRKVYMYYWPGCEVEILGVRPTYCLEYKNVPTDINFANAVSDALDSFKSG RADLAAIYHERIDVEGHHYGPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSD HGMTDIFWMDKVIELNKYISLNDLQQVKDRGPVVSLWPAPGKHSEIYNKLSTVEHMTVYE KEAIPSRFYYKKGKFVSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNEL MDMRGIFLAFGPDFKSNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRAST APPVWPSHCALALILLFLLA > DME ID: DME0531 DME Name: Alanine aminotransferase 1 (GPT) PDB ID: Not Available MASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPF TEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSL GAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRT GVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPRALCVI NPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPY AGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDL VVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQL PPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLL LEKLSRFHAKFTLEYS > DME ID: DME0532 DME Name: Phosphoserine aminotransferase (PSAT1) PDB ID: Not Available MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLV RELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGT INIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSN FLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLY NTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVCPVEPQNRSK MNIPFRIGNAKGDDALEKRFLDKALELNMLSLKGHRSVGGIRASLYNAVTIEDVQKLAAF MKKFLEMHQL > DME ID: DME0533 DME Name: Carnitine O-acetyltransferase (CRAT) PDB ID: 1NM8; 1S5O MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSE EEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSP GVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSC RVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSS LQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVY RSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIE YTKKPELVRSPLVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKD FPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVK AMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMD TSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNA ARLAHYLEKALLDMRALLQSHPRAKL > DME ID: DME0534 DME Name: N-acetylglutamate synthase (NAGS) PDB ID: 4K30 MATALMAVVLRAAAVAPRLRGRGGTGGARRLSCGARRRAARGTSPGRRLSTAWSQPQPPP EEYAGADDVSQSPVAEEPSWVPSPRPPVPHESPEPPSGRSLVQRDIQAFLNQCGASPGEA RHWLTQFQTCHHSADKPFAVIEVDEEVLKCQQGVSSLAFALAFLQRMDMKPLVVLGLPAP TAPSGCLSFWEAKAQLAKSCKVLVDALRHNAAAAVPFFGGGSVLRAAEPAPHASYGGIVS VETDLLQWCLESGSIPILCPIGETAARRSVLLDSLEVTASLAKALRPTKIIFLNNTGGLR DSSHKVLSNVNLPADLDLVCNAEWVSTKERQQMRLIVDVLSRLPHHSSAVITAASTLLTE LFSNKGSGTLFKNAERMLRVRSLDKLDQGRLVDLVNASFGKKLRDDYLASLRPRLHSIYV SEGYNAAAILTMEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNP INPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFHKPASDPGS > DME ID: DME0535 DME Name: Thyroxine 5-deiodinase (DIO3) PDB ID: Not Available MPRQATSRLVVGEGEGSQGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLW LLDFLCIRKHFLGRRRRGQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHG QKLDFFKQAHEGGPAPNSEVVLPDGFQSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAF QRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCA LVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGAR PRRV > DME ID: DME0536 DME Name: Phosphoglucomutase 3 (PGM3) PDB ID: Not Available MDLGAITKYSALHAKPNGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVM VTASHNPEEDNGVKLVDPLGEMLAPSWEEHATCLANAEEQDMQRVLIDISEKEAVNLQQD AFVVIGRDTRPSSEKLSQSVIDGVTVLGGQFHDYGLLTTPQLHYMVYCRNTGGRYGKATI EGYYQKLSKAFVELTKQASCSGDEYRSLKVDCANGIGALKLREMEHYFSQGLSVQLFNDG SKGKLNHLCGADFVKSHQKPPQGMEIKSNERCCSFDGDADRIVYYYHDADGHFHLIDGDK IATLISSFLKELLVEIGESLNIGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKA QEFDIGVYFEANGHGTALFSTAVEMKIKQSAEQLEDKKRKAAKMLENIIDLFNQAAGDAI SDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVQVADRRVISTTDAERQAVTPPGLQEA INDLVKKYKLSRAFVRPSGTEDVVRVYAEADSQESADHLAHEVSLAVFQLAGGIGERPQP GF > DME ID: DME0537 DME Name: UDP-N-acetylhexosamine pyrophosphorylase (AGX) PDB ID: 1JV1; 1JV3; 1JVD; 1JVG MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQ CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI > DME ID: DME0538 DME Name: Cyclic ADP-ribose hydrolase 1 (CD38) PDB ID: 2EF1; 2HCT; 2I65; 2I66; 2I67; 2O3Q; 2O3R; 2O3S; 2O3T MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFP ETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCN KILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDC SNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEA WVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI > DME ID: DME0539 DME Name: Nicotinate-nucleotide adenylyltransferase 2 (NMNAT2) PDB ID: Not Available MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ LYINASG > DME ID: DME0540 DME Name: MOSC domain-containing protein 1 (MARC1) PDB ID: 6FW2 MGAAGSSALARFVLLAQSRPGWLGVAALGLTAVALGAVAWRRAWPTRRRRLLQQVGTVAQ LWIYPVKSCKGVPVSEAECTAMGLRSGNLRDRFWLVINQEGNMVTARQEPRLVLISLTCD GDTLTLSAAYTKDLLLPIKTPTTNAVHKCRVHGLEIEGRDCGEATAQWITSFLKSQPYRL VHFEPHMRPRRPHQIADLFRPKDQIAYSDTSPFLILSEASLADLNSRLEKKVKATNFRPN IVISGCDVYAEDSWDELLIGDVELKRVMACSRCILTTVDPDTGVMSRKEPLETLKSYRQC DPSERKLYGKSPLFGQYFVLENPGTIKVGDPVYLLGQ > DME ID: DME0541 DME Name: MOSC domain-containing protein 2 (MARC2) PDB ID: Not Available MGASSSSALARLGLPARPWPRWLGVAALGLAAVALGTVAWRRAWPRRRRRLQQVGTVAKL WIYPVKSCKGVPVSEAECTAMGLRSGNLRDRFWLVIKEDGHMVTARQEPRLVLISIIYEN NCLIFRAPDMDQLVLPSKQPSSNKLHNCRIFGLDIKGRDCGNEAAKWFTNFLKTEAYRLV QFETNMKGRTSRKLLPTLDQNFQVAYPDYCPLLIMTDASLVDLNTRMEKKMKMENFRPNI VVTGCDAFEEDTWDELLIGSVEVKKVMACPRCILTTVDPDTGVIDRKQPLDTLKSYRLCD PSERELYKLSPLFGIYYSVEKIGSLRVGDPVYRMV > DME ID: DME0542 DME Name: Oxaloacetate decarboxylase (FAHD1) PDB ID: 1SAW; 6FOG; 6FOH MGIMAASRPLSRFWEWGKNIVCVGRNYADHVREMRSAVLSEPVLFLKPSTAYAPEGSPIL MPAYTRNLHHELELGVVMGKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWT LAKSFTASCPVSAFVPKEKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKII TLEEGDIILTGTPKGVGPVKENDEIEAGIHGLVSMTFKVEKPEY > DME ID: DME0543 DME Name: Phenylethanolamine N-methyltransferase (PNMT) PDB ID: 1N7J; 1YZ3; 2AN3; 2AN4; 2AN5; 2G70; 2G71; 2G72; 2G8N MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRC LAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGA FNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVS AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVR EALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL > DME ID: DME0544 DME Name: Maillard deglycase (PARK7) PDB ID: 1PDV; 1PDW; 1PE0; 1Q2U; 1SOA; 1UCF; 2OR3; 2R1T; 2R1U MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLED AKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFG SKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQ VKAPLVLKD > DME ID: DME0545 DME Name: Lecithin-cholesterol acyltransferase (LCAT) PDB ID: 4X96; 4XWG; 4XX1; 5BV7; 5TXF; 6MVD MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQL EAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGV QIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEY YRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGS IKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGR DFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDP VGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLG AYRQGPPASPTASPEPPPPE > DME ID: DME0546 DME Name: Glucosidase II beta (PRKCSH) PDB ID: Not Available MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKD GSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKG RKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVK EEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPEL DTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEP KEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYD EQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTT NEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTT VRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL > DME ID: DME0547 DME Name: Neutral alpha-glucosidase AB (GANAB) PDB ID: Not Available MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH QRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYG PMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVP VLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETG IIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHN LPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVH EELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVW NDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVL ARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELL VRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHR EGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQ SYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTA QGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKP AAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR > DME ID: DME0548 DME Name: Dimethylarginine dimethylaminohydrolase 1 (DDAH1) PDB ID: 2JAI; 2JAJ; 3I2E; 3I4A; 3P8E; 3P8P; 6DGE MAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLGL QVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEMK DENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSM AGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYLNIPNKGHVLLHRTPE EYPESAKVYEKLKDHMLIPVSMSELEKVDGLLTCCSVLINKKVDS > DME ID: DME0549 DME Name: Pyrrolidone-carboxylate peptidase (PGPI) PDB ID: Not Available MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPA LWEKHSPQLVVHVGVSGMATTVTLEKCGHNKGYKGLDNCRFCPGSQCCVEDGPESIDSII DMDAVCKRVTTLGLDVSVTISQDAGRYLCDFTYYTSLYQSHGRSAFVHVPPLGKPYNADQ LGRALRAIIEEMLDLLEQSEGKINYCHKH > DME ID: DME0550 DME Name: Trans-L-3-hydroxyproline dehydratase (L3HYPDH) PDB ID: Not Available MESALAVPRLPPHDPGTPVLSVVDMHTGGEPLRIVLAGCPEVSGPTLLAKRRYMRQHLDH VRRRLMFEPRGHRDMYGAVLVPSELPDAHLGVLFLHNEGYSSMCGHAVLALGRFALDFGL VPAPPAGTREARVNIHCPCGLVTAFVACEDGRSHGPVRFHSVPAFVLATDLMVDVPGHGK VMVDIAYGGAFYAFVTAEKLGLDICSAKTRDLVDAASAVTEAVKAQFKINHPDSEDLAFL YGTILTDGKDAYTKEPTTNICVFADEQVDRSPTGSGVTARIALQYHKGLLELNQMRAFKS SATGSVFTGKAVREAKCGDFKAVIVEVSGQAHYTGTASFIIEDDDPLRDGFLLK > DME ID: DME0551 DME Name: Xylosylprotein 4-beta-galactosyltransferase (XGalT-1) PDB ID: 4IRP; 4IRQ MFPSRRKAAQLPWEDGRSGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARA VRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLS RKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEA GPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGL QLFRPSGITTGYKTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYHVASRTAL SVGGAPCTVLNIMLDCDKTATPWCTFS > DME ID: DME0552 DME Name: Histo-blood group ABO system transferase (NAGAT) PDB ID: 1LZI; 1LZJ; 1R7T; 1R7U; 1R7V; 1R7X; 1R7Y; 1R80; 1R81 MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDH LQRVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTV FAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKR WQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSS REAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVW HDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP > DME ID: DME0559 DME Name: Collagen galactosyltransferase (COLGALT2) PDB ID: Not Available MAARPAATLAWSLLLLSSALLREGCRARFVAERDSEDDGEEPVVFPESPLQSPTVLVAVL ARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEIFREWLKNVQRLYHYVEWRP MDEPESYPDEIGPKHWPTSRFAHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNL LIAENKTIVAPMLESRGLYSNFWCGITPKGFYKRTPDYVQIREWKRTGCFPVPMVHSTFL IDLRKEASDKLTFYPPHQDYTWTFDDIIVFAFSSRQAGIQMYLCNREHYGYLPIPLKPHQ TLQEDIENLIHVQIEAMIDRPPMEPSQYVSVVPKYPDKMGFDEIFMINLKRRKDRRDRML RTLYEQEIEVKIVEAVDGKALNTSQLKALNIEMLPGYRDPYSSRPLTRGEIGCFLSHYSV WKEVIDRELEKTLVIEDDVRFEHQFKKKLMKLMDNIDQAQLDWELIYIGRKRMQVKEPEK AVPNVANLVEADYSYWTLGYVISLEGAQKLVGANPFGKMLPVDEFLPVMYNKHPVAEYKE YYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETSTIWDNETVATDWDRTHAWKSRKQSR IYSNAKNTEALPPPTSLDTVPSRDEL > DME ID: DME0560 DME Name: Pyroglutamase (OPLAH) PDB ID: Not Available MGSPEGRFHFAIDRGGTFTDVFAQCPGGHVRVLKLLSEDPANYADAPTEGIRRILEQEAG MLLPRDQPLDSSHIASIRMGTTVATNALLERKGERVALLVTRGFRDLLHIGTQARGDLFD LAVPMPEVLYEEVLEVDERVVLHRGEAGTGTPVKGRTGDLLEVQQPVDLGALRGKLEGLL SRGIRSLAVVLMHSYTWAQHEQQVGVLARELGFTHVSLSSEAMPMVRIVPRGHTACADAY LTPAIQRYVQGFCRGFQGQLKDVQVLFMRSDGGLAPMDTFSGSSAVLSGPAGGVVGYSAT TYQQEGGQPVIGFDMGGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRL FFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGENQPLSP EASRKALEAVATEVNSFLTNGPCPASPLSLEEVAMGFVRVANEAMCRPIRALTQARGHDP SAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLLYA PETFVQLDQRLSRLEEQCVDALQAQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATA RSPRAGDFGAAFVERYMREFGFVIPERPVVVDDVRVRGTGRSGLRLEDAPKAQTGPPRVD KMTQCYFEGGYQETPVYLLAELGYGHKLHGPCLIIDSNSTILVEPGCQAEVTKTGDICIS VGAEVPGTVGPQLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDG GLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFW PGQTRPVFYVASRGHHADIGGITPGSMPPHSTMLQQEGAVFLSFKLVQGGVFQEEAVTEA LRAPGKVPNCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANA ELAVRDMLRAFGTSRQARGLPLEVSSEDHMDDGSPIRLRVQISLSQGSAVFDFSGTGPEV FGNLNAPRAVTLSALIYCLRCLVGRDIPLNQGCLAPVRVVIPRGSILDPSPEAAVVGGNV LTSQRVVDVILGAFGACAASQGCMNNVTLGNAHMGYYETVAGGAGAGPSWHGRSGVHSHM TNTRITDPEILESRYPVILRRFELRRGSGGRGRFRGGDGVTRELLFREEALLSVLTERRA FRPYGLHGGEPGARGLNLLIRKNGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDPA PPPGSPPQALAFPEHGSVYEYRRAQEAV > DME ID: DME0561 DME Name: Matrix metalloproteinase-2 (MMP-2) PDB ID: 1EAK; 1GEN; 1GXD; 1HOV; 1J7M; 1KS0; 1QIB; 1RTG; 3AYU MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC > DME ID: DME0562 DME Name: Cathepsin H (CTSH) PDB ID: 1BZN; 6CZK; 6CZS MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV > DME ID: DME0563 DME Name: Carboxypeptidase M (CPM) PDB ID: 1UWY MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP DHSAATKPSLFLFLVSLLHIFFK > DME ID: DME0564 DME Name: Matrix metalloproteinase-9 (MMP-9) PDB ID: 1ITV; 1L6J; 1LKG; 2OVX; 2OVZ; 2OW0; 2OW1; 2OW2; 4H1Q MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEM RGESKSLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHN ITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYP FDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAACHFPFIFEGRS YSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQFPFIFQGQSYS ACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVFPFTFLGKEYST CTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY PMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSER PTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNIFDAIAEIGNQLYLFKDGKYW RFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLGPRR LDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLD THDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED > DME ID: DME0565 DME Name: D-amino-acid oxidase (DAO) PDB ID: 2E49; 2E4A; 2E82; 2GNZ; 3CUK; 3G3E; 3W4I; 3W4J; 3W4K MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL > DME ID: DME0566 DME Name: Prostaglandin dehydrogenase 1 (HPGD) PDB ID: 2GDZ MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG AIMKITTSKGIHFQDYDTTPFQAKTQ > DME ID: DME0567 DME Name: Quinone reductase 2 (NQO2) PDB ID: 1XI2; 1ZX1; 2BZS; 2QMY; 2QMZ; 2QR2; 2QWX; 2QX4; 2QX6 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ > DME ID: DME0568 DME Name: Carboxyl ester lipase (CEL) PDB ID: 1F6W; 1JMY; 6H0T; 6H0V; 6H18; 6H19; 6H1A MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTK ALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPV MIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPG NYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQS GVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYP MLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVT EEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLR YWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSG APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP PTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDS GAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF > DME ID: DME0569 DME Name: Cytosol aminopeptidase (LAP3) PDB ID: Not Available MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA > DME ID: DME0570 DME Name: Sepiapterin reductase (SPR) PDB ID: 4J7U; 4J7X; 4XWY; 4Z3K; 6I6C; 6I6F; 6I6P; 6I6T; 6I6V MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK LLSLLEKDEFKSGAHVDFYDK > DME ID: DME0571 DME Name: Squalene synthase (FDFT1) PDB ID: 3LEE; 3Q2Z; 3Q30; 3V66; 3VJ8; 3VJ9; 3VJA; 3VJB; 3VJC MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQA LDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQ VLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVG IGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYV KKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATL AACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTR QIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH > DME ID: DME0572 DME Name: Lipocalin-type prostaglandin-D synthase (PTGDS) PDB ID: 3O22; 3O2Y; 4IMN; 4IMO; 4ORR; 4ORS; 4ORU; 4ORW; 4ORX MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSV VETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFL PQTDKCMTEQ > DME ID: DME0573 DME Name: Cathepsin K (CTSK) PDB ID: 1AU2; 1AU3; 1AU4; 1AYU; 1AYV; 1AYW; 1BGO; 1BY8; 1MEM MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE NWGNKGYILMARNKNNACGIANLASFPKM > DME ID: DME0574 DME Name: Prolyl endopeptidase (PREP) PDB ID: 3DDU MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIR GLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILS DDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTH DGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAEL SDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVF TFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNI LQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPR VFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISI TPNYSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKE GYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYG CSDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIV GRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNVDWIP > DME ID: DME0575 DME Name: Ras proteins prenyltransferase alpha (FNTA) PDB ID: 1LD8; 1MZC; 1S63; 1SA4; 1TN6; 2F0Y; 2H6F; 2H6G; 2H6H MAATEGVGEAAQGGEPGQPAQPPPQPHPPPPQQQHKEEMAAEAGEAVASPMDDGFVSLDS PSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLT RDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLR DPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQR YFVISNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLL DLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIG RSLQSKHSTENDSPTNVQQ > DME ID: DME0576 DME Name: N-acetyl-D-glucosamine 2-epimerase (AGE) PDB ID: Not Available MSKGLPARQDMEKERETLQAWKERVGQELDRVVAFWMEHSHDQEHGGFFTCLGREGRVYD DLKYVWLQGRQVWMYCRLYRTFERFRHAQLLDAAKAGGEFLLRYARVAPPGKKCAFVLTR DGRPVKVQRTIFSECFYTMAMNELWRATGEVRYQTEAVEMMDQIVHWVQEDASGLGRPQL QGAPAAEPMAVPMMLLNLVEQLGEADEELAGKYAELGDWCARRILQHVQRDGQAVLENVS EGGKELPGCLGRQQNPGHTLEAGWFLLRHCIRKGDPELRAHVIDKFLLLPFHSGWDPDHG GLFYFQDADNFCPTQLEWAMKLWWPHSEAMIAFLMGYSDSGDPVLLRLFYQVAEYTFRQF RDPEYGEWFGYLSREGKVALSIKGGPFKGCFHVPRCLAMCEEMLGALLSRPAPAPSPAPT PACRGAE > DME ID: DME0577 DME Name: Thimet oligopeptidase (THOP1) PDB ID: 1S4B; 2O36 MKPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVS YESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQ RIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNK NLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKV EEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQ KLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYF PVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREG KYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMH QLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLI ESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGH LAGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRR FLGRDPKQDAFLLSKGLQVGGCEPEPQVC > DME ID: DME0578 DME Name: Sorbitol dehydrogenase (SORD) PDB ID: 1PL6; 1PL7; 1PL8 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP > DME ID: DME0579 DME Name: Glutamate carboxypeptidase II (FOLH1) PDB ID: 2C6G; 2C6P; 2CIJ; 2JBJ; 2JBK; 2OOT; 2OR4; 2PVV; 2PVW MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIKSSNEATNITPKHNMKA FLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYP NKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPPFSAFSPQGMPEGDLVYVNYA RTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGVILYSDPADYFAPGVK SYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVHPIGYY DAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIG TLRGAVEPDRYVILGGHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEGWRPRRTILFAS WDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKE LKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKN WETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDY AVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIV LRMMNDQLMFLERAFIDPLGLPDRPFYRHVIYAPSSHNKYAGESFPGIYDALFDIESKVD PSKAWGEVKRQIYVAAFTVQAAAETLSEVA > DME ID: DME0580 DME Name: PABA peptide hydrolase (MEP1B) PDB ID: 4GWM; 4GWN MDLWNLSWFLFLDALLVISGLATPENFDVDGGMDQDIFDINEGLGLDLFEGDIRLDRAQI RNSIIGEKYRWPHTIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWAGETNYISVFK GSGCWSSVGNRRVGKQELSIGANCDRIATVQHEFLHALGFWHEQSRSDRDDYVRIMWDRI LSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKTAFQNGTEPTIVTRISDFEDVIGQRMD FSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCGMIQSSGDNADWQRVSQVPRGPESDHS NMGQCQGSGFFMHFDSSSVNVGATAVLESRTLYPKRGFQCLQFYLYNSGSESDQLNIYIR EYSADNVDGNLTLVEEIKEIPTGSWQLYHVTLKVTKKFRVVFEGRKGSGASLGGLSIDDI NLSETRCPHHIWHIRNFTQFIGSPNGTLYSPPFYSSKGYAFQIYLNLAHVTNAGIYFHLI SGANDDQLQWPCPWQQATMTLLDQNPDIRQRMSNQRSITTDPFMTTDNGNYFWDRPSKVG TVALFSNGTQFRRGGGYGTSAFITHERLKSRDFIKGDDVYILLTVEDISHLNSTQIQLTP APSVQDLCSKTTCKNDGVCTVRDGKAECRCQSGEDWWYMGERCEKRGSTRDTIVIAVSST VAVFALMLIITLVSVYCTRKKYRERMSSNRPNLTPQNQHAF > DME ID: DME0581 DME Name: Metallo-endopeptidase-like 1 (MMEL1) PDB ID: Not Available MGKSEGPVGMVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLAS RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFAC GGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSV IEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWND DQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCL VQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLS SVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRV NYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFV ETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENS LQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSW DLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYA QVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW > DME ID: DME0582 DME Name: Polyamine oxidase (PAOX) PDB ID: Not Available MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCF GGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGA SVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLK LAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFF DPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAW FRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPK SVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYS TTHGALLSGWREADRLLSLWAPQVQQPRPRL > DME ID: DME0583 DME Name: Retinol dehydrogenase 5 (RDH5) PDB ID: Not Available MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCL TPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGP TPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKF GLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGA FLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPAS LVDAVLTWVLPKPAQAVY > DME ID: DME0584 DME Name: Carboxymethylenebutenolidase (CMBL) PDB ID: Not Available MANEAYPCPCDIGHRLEYGGLGREVQVEHIKAYVTKSPVDAGKAVIVIQDIFGWQLPNTR YIADMISGNGYTTIVPDFFVGQEPWDPSGDWSIFPEWLKTRNAQKIDREISAILKYLKQQ CHAQKIGIVGFCWGGTAVHHLMMKYSEFRAGVSVYGIVKDSEDIYNLKNPTLFIFAENDV VIPLKDVSLLTQKLKEHCKVEYQIKTFSGQTHGFVHRKREDCSPADKPYIDEARRNLIEW LNKYM > DME ID: DME0585 DME Name: Pyridoxal phosphate phosphatase (PDXP) PDB ID: 2CFR; 2CFS; 2CFT; 2OYC; 2P27; 2P69; 5GYN MARCERLRGAALRDVLGRAQGVLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNN SRRARPELALRFARLGFGGLRAEQLFSSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRA ELRAAGLRLAGDPSAGDGAAPRVRAVLVGYDEHFSFAKLREACAHLRDPECLLVATDRDP WHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRL ETDILFGHRCGMTTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADLTEGLED > DME ID: DME0586 DME Name: Short-chain dehydrogenase/reductase retSDR8 (DHRS9) PDB ID: Not Available MLFWVLGLLILCGFLWTRKGKLKIEDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAAC LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGGGYTPSK YAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNLADPVKVIEKKLAIWEQLSPDIKQQYGE GYIEKSLDKLKGNKSYVNMDLSPVVECMDHALTSLFPKTHYAAGKDAKIFWIPLSHMPAA LQDFLLLKQKAELANPKAV > DME ID: DME0587 DME Name: Agmatine ureohydrolase (AGMAT) PDB ID: Not Available MLRLLASGCARGPGPGVGARPAAGLFHPGRRQSRQASDAPRNQPPSPEFVARPVGVCSMM RLPVQTSPEGLDAAFIGVPLDTGTSNRPGARFGPRRIREESVMLGTVNPSTGALPFQSLM VADLGDVNVNLYNLQDSCRRIQEAYEKIVAAGCIPLTLGGDHTITYPILQAMAKKHGPVG LLHVDAHTDTTDKALGEKLYHGAPFRRCVDEGLLDCKRVVQIGIRGSSTTLDPYRYNRSQ GFRVVLAEDCWMKSLVPLMGEVRQQMGGKPIYISFDIDALDPAYAPGTGTPEIAGLTPSQ ALEIIRGCQGLNVMGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV > DME ID: DME0588 DME Name: Serine racemase (SRR) PDB ID: 3L6B; 3L6R; 5X2L MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGA LNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQA YGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDAL VVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV KSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQT VSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV > DME ID: DME0589 DME Name: Prostaglandin E synthase 2 (PTGES2) PDB ID: Not Available MDPAARVVRALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAARKGSPRLLG AAALALGGALGLYHTARWHLRAQDLHAERSAAQLSLSSRLQLTLYQYKTCPFCSKVRAFL DFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQ PLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADD WLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQ DNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQ PWYLRVERAITEASPAH > DME ID: DME0590 DME Name: Spermine oxidase (SMOX) PDB ID: Not Available MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHI GGRVQSVKLGHATFELGATWIHGSHGNPIYHLAEANGLLEETTDGERSVGRISLYSKNGV ACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQNSVGVFTREEVRNRI RNDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIPSGFM RVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGPEIEPRGEGDHNHDTGEGGQGGEEP RGGRWDEDEQWSVVVECEDCELIPADHVIVTVSLGVLKRQYTSFFRPGLPTEKVAAIHRL GIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESHTLTYPPELWYRKICGFDVLYPPERY GHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRG SYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREA ARLIEMYRDLFQQGT > DME ID: DME0591 DME Name: Sterol Delta(7)-reductase (DHCR7) PDB ID: Not Available MAAKSQPNIPKAKSLDGVTNDRTASQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMA CDQYSCALTGPVVDIVTGHARLSDIWAKTPPITRKAAQLYTLWVTFQVLLYTSLPDFCHK FLPGYVGGIQEGAVTPAGVVNKYQINGLQAWLLTHLLWFANAHLLSWFSPTIIFDNWIPL LWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFN GRPGIVAWTLINLSFAAKQRELHSHVTNAMVLVNVLQAIYVIDFFWNETWYLKTIDICHD HFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPHAVGVLLLGLVGYYIFRVANHQKDL FRRTDGRCLIWGRKPKVIECSYTSADGQRHHSKLLVSGFWGVARHFNYVGDLMGSLAYCL ACGGGHLLPYFYIIYMAILLTHRCLRDEHRCASKYGRDWERYTAAVPYRLLPGIF > DME ID: DME0592 DME Name: Dipeptidyl peptidase II (DPP7) PDB ID: 3JYH; 3N0T; 4EBB MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ QPALRGGPRLSL > DME ID: DME0593 DME Name: Carboxypeptidase A4 (CPA4) PDB ID: 2BO9; 2BOA; 2PCU; 4A94; 4BD9 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL Y > DME ID: DME0594 DME Name: Poly [ADP-ribose] polymerase 3 (PARP3) PDB ID: 3C4H; 3CE0; 3FHB; 4GV0; 4GV2; 4GV4; 4L6Z; 4L70; 4L7L MAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGT QVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQSKINHFTRLED AKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRV QPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEAL KGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQA VSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWK VNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGIYFASENS KSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPT QDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL > DME ID: DME0600 DME Name: Cytochrome P450 26C1 (CYP26C1) PDB ID: Not Available MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFG ETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQS AHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVS VYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRAR DQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFT TASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSL AALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAV YRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTA RWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL > DME ID: DME0601 DME Name: Short-chain dehydrogenase/reductase retSDR4 (DHRS7) PDB ID: Not Available MNWELLLWLLVLCALLLLLVQLLRFLRADGDLTLLWAEWQGRRPEWELTDMVVWVTGASS GIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEA ATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIER KQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSN IVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQPFLLVTYLWQY MPTWAWWITNKMGKKRIENFKSGVDADSSYFKIFKTKHD > DME ID: DME0602 DME Name: UDP-glucuronosyltransferase 1A5 (UGT1A5) PDB ID: Not Available MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH > DME ID: DME0603 DME Name: Hydroxyacylglutathione hydrolase (HAGH) PDB ID: 1QH3; 1QH5; 2F50 MVVGRGLLGRRSLAALGAACARRGLGPALLGVFCHTDLRKNLTVDEGTMKVEVLPALTDN YMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESG LKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFT GDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAA IREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVTTMRAVRREK DQFKMPRD > DME ID: DME0606 DME Name: Glutathione S-transferase alpha-4 (GSTA4) PDB ID: 1GUL; 1GUM; 3IK7 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP > DME ID: DME0607 DME Name: D-aspartate oxidase (DDO) PDB ID: Not Available MDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTP IHTQKQWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMT EAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWELHPSFDIVV NCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKG DWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPV VHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL > DME ID: DME0608 DME Name: Cytochrome P450 7B1 (CYP7B1) PDB ID: Not Available MAGEVSAATGRFSLERLGLPGLALAAALLLLALCLLVRRTRRPGEPPLIKGWLPYLGVVL NLRKDPLRFMKTLQKQHGDTFTVLLGGKYITFILDPFQYQLVIKNHKQLSFRVFSNKLLE KAFSISQLQKNHDMNDELHLCYQFLQGKSLDILLESMMQNLKQVFEPQLLKTTSWDTAEL YPFCSSIIFEITFTTIYGKVIVCDNNKFISELRDDFLKFDDKFAYLVSNIPIELLGNVKS IREKIIKCFSSEKLAKMQGWSEVFQSRQDVLEKYYVHEDLEIGAHHLGFLWASVANTIPT MFWAMYYLLRHPEAMAAVRDEIDRLLQSTGQKKGSGFPIHLTREQLDSLICLESSIFEAL RLSSYSTTIRFVEEDLTLSSETGDYCVRKGDLVAIFPPVLHGDPEIFEAPEEFRYDRFIE DGKKKTTFFKRGKKLKCYLMPFGTGTSKCPGRFFALMEIKQLLVILLTYFDLEIIDDKPI GLNYSRLLFGIQYPDSDVLFRYKVKS > DME ID: DME0609 DME Name: Dehydrogenase/reductase retSDR3 (HSD17B14) PDB ID: 1YDE; 5EN4; 5HS6 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG IELLVTGGAELGYGCKASRSTPVDAPDIPS > DME ID: DME0610 DME Name: Glutathione peroxidase 6 (GPX6) PDB ID: Not Available MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFA GKHVLFVNVAAYUGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLK YVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIR WNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH > DME ID: DME0611 DME Name: Dehydrogenase/reductase retSDR2 (HSD17B11) PDB ID: 1YB1 MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVP FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPE EVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKQKISVKFDAVIGYKMKAQ > DME ID: DME0613 DME Name: Glutathione S-transferase mu-4 (GSTM4) PDB ID: 4GTU MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK > DME ID: DME0614 DME Name: Sulfotransferase 1C2 (SULT1C2) PDB ID: 3BFX MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVD MIEQNGDVEKCQRAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQLLPPSFW ENNCKFLYVARNAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGW WEMKDRHQILFLFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTN RSTVSKSILDQSISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFCMEL > DME ID: DME0616 DME Name: Docosahexaenoic acid omega-hydroxylase (CYP4F11) PDB ID: Not Available MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ > DME ID: DME0619 DME Name: Oxysterol 7-alpha-hydroxylase (CYP39A1) PDB ID: Not Available MELISPTVIIILGCLALFLLLQRKNLRRPPCIKGWIPWIGVGFEFGKAPLEFIEKARIKY GPIFTVFAMGNRMTFVTEEEGINVFLKSKKVDFELAVQNIVYRTASIPKNVFLALHEKLY IMLKGKMGTVNLHQFTGQLTEELHEQLENLGTHGTMDLNNLVRHLLYPVTVNMLFNKSLF STNKKKIKEFHQYFQVYDEDFEYGSQLPECLLRNWSKSKKWFLELFEKNIPDIKACKSAK DNSMTLLQATLDIVETETSKENSPNYGLLLLWASLSNAVPVAFWTLAYVLSHPDIHKAIM EGISSVFGKAGKDKIKVSEDDLENLLLIKWCVLETIRLKAPGVITRKVVKPVEILNYIIP SGDLLMLSPFWLHRNPKYFPEPELFKPERWKKANLEKHSFLDCFMAFGSGKFQCPARWFA LLEVQMCIILILYKYDCSLLDPLPKQSYLHLVGVPQPEGQCRIEYKQRI > DME ID: DME0620 DME Name: Serum paraoxonase/arylesterase 2 (PON2) PDB ID: Not Available MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL > DME ID: DME0621 DME Name: Microsomal glutathione S-transferase 1 (MGST1) PDB ID: Not Available MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK KYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIA YLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL > DME ID: DME0622 DME Name: UDP-glucuronosyltransferase 2A1 (UGT2A1) PDB ID: Not Available MLNNLLLFSLQISLIGTTLGGNVLIWPMEGSHWLNVKIIIDELIKKEHNVTVLVASGALF ITPTSNPSLTFEIYRVPFGKERIEGVIKDFVLTWLENRPSPSTIWRFYQEMAKVIKDFHM VSQEICDGVLKNQQLMAKLKKSKFEVLVSDPVFPCGDIVALKLGIPFMYSLRFSPASTVE KHCGKVPYPPSYVPAVLSELTDQMSFTDRIRNFISYHLQDYMFETLWKSWDSYYSKALGR PTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFIQSSGKN GVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQLFDWIPQNDL LGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTS VDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHD LTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE > DME ID: DME0623 DME Name: Epoxide hydrolase 1 (EPHX1) PDB ID: Not Available MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEI HDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKI EGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV ICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVP SHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYM HIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVML YWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKL ISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ > DME ID: DME0624 DME Name: Cytochrome P450 7A1 (CYP7A1) PDB ID: 3DAX; 3SN5; 3V8D MMTTSLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQ RKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSIDPMDGN TTENINDTFIKTLQGHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMF EAGYLTIFGRDLTRRDTQKAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNAREKLAE SLRHENLQKRESISELISLRMFLNDTLSTFDDLEKAKTHLVVLWASQANTIPATFWSLFQ MIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLRLSSAS LNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTK TTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELIEGQAKCPPLD QSRAGLGILPPLNDIEFKYKFKHL > DME ID: DME0628 DME Name: Short-chain dehydrogenase/reductase SDR19C1 (DHRS1) PDB ID: 2QQ5 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN NVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVPYGVGKAACDKLAADCAHE LRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALA TDPNILSLSGKVLPSCDLARRYGLRDVDGRPVQDYLSLSSVLSHVSGLGWLASYLPSFLR VPKWIIALYTSKF > DME ID: DME0631 DME Name: Cytochrome P450 8B1 (CYP8B1) PDB ID: Not Available MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGTVPWLGHAMAFRKNMFEFLKRM RTKHGDVFTVQLGGQYFTFVMDPLSFGSILKDTQRKLDFGQYAKKLVLKVFGYRSVQGDH EMIHSASTKHLRGDGLKDLNETMLDSLSFVMLTSKGWSLDASCWHEDSLFRFCYYILFTA GYLSLFGYTKDKEQDLLQAGELFMEFRKFDLLFPRFVYSLLWPREWLEVGRLQRLFHKML SVSHSQEKEGISNWLGNMLQFLREQGVPSAMQDKFNFMMLWASQGNTGPTSFWALLYLLK HPEAIRAVREEATQVLGEARLETKQSFAFKLGALQHTPVLDSVVEETLRLRAAPTLLRLV HEDYTLKMSSGQEYLFRHGDILALFPYLSVHMDPDIHPEPTVFKYDRFLNPNGSRKVDFF KTGKKIHHYTMPWGSGVSICPGRFFALSEVKLFILLMVTHFDLELVDPDTPLPHVDPQRW GFGTMQPSHDVRFRYRLHPTE > DME ID: DME0632 DME Name: Chondroitin 6-sulfotransferase (CHST3) PDB ID: Not Available MEKGLTLPQDCRDFVHSLKMRSKYALFLVFVVIVFVFIEKENKIISRVSDKLKQIPQALA DANSTDPALILAENASLLSLSELDSAFSQLQSRLRNLSLQLGVEPAMEAAGEEEEEQRKE EEPPRPAVAGPRRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVSFEPGGAN AAGSALVYRDVLKQLFLCDLYVLEHFITPLPEDHLTQFMFRRGSSRSLCEDPVCTPFVKK VFEKYHCKNRRCGPLNVTLAAEACRRKEHMALKAVRIRQLEFLQPLAEDPRLDLRVIQLV RDPRAVLASRMVAFAGKYKTWKKWLDDEGQDGLREEEVQRLRGNCESIRLSAELGLRQPA WLRGRYMLVRYEDVARGPLQKAREMYRFAGIPLTPQVEDWIQKNTQAAHDGSGIYSTQKN SSEQFEKWRFSMPFKLAQVVQAACGPAMRLFGYKLARDAAALTNRSVSLLEERGTFWVT > DME ID: DME0633 DME Name: Glutathione S-transferase zeta-1 (GSTZ1) PDB ID: 1FW1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDRGQQFSKDFQALNPMKQVP TLKIDGITIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLK QVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL TPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA > DME ID: DME0634 DME Name: Dimethylaniline oxidase 5 (FMO5) PDB ID: Not Available MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVI INTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDF ATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNP EGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRL THFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKV KGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPN LERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKRY VESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGK WDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYF > DME ID: DME0637 DME Name: Dimethylaniline oxidase 4 (FMO4) PDB ID: Not Available MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVT NVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFS ETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE GFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCC SFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKT SVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNL ERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVF KDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWD GARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLV RDKLQDRMSPYLVSLWRG > DME ID: DME0638 DME Name: UDP-glucuronosyltransferase 2B28 (UGT2B28) PDB ID: Not Available MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSA SILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQEQEILWEFH DIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTI ERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVL GRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAKPLPKEMEEFVQSSG ENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQN DLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTM SSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAA RDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFARKGKKGKRD > DME ID: DME0640 DME Name: UDP-glucuronosyltransferase 2B11 (UGT2B11) PDB ID: Not Available MTLKWTSVLLLIHLSCYFSSGSCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSA SILFDPNDASTLKFEVYPTSLTKTEFENIIMQQVKRWSDIRKDSFWLYFSQEQEILWELY DIFRNFCKDVVSNKKVMKKLQESRFDIVFADAVFPCGELLAALLNIRFVYSLRFTPGYTI ERHSGGLIFPPSYIPIVMSKLSDQMTFMERVKNMIYVLYFDFWFQMSDMKKWDQFYSEVL GRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFHCKPAKPLPKEMEEFVQSSG ENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQN DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTM SSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKGAKHLRVAA HDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFWKFARKGKKGKRD > DME ID: DME1002 DME Name: Dipeptidase (pepV) PDB ID: Not Available MTTIDFKAEVEKLKDALMEDLFSLLRIDSAMDMEHADAENPFGPGPRKALDAFLKIAERD GYTTKNYDNYVGHFEYENGASDDAEVLGIIGHLDVVPAGSGWDSNPFEPEIRNGNLYARG ASDDKGPTVACYYALKILKELNLPLSKKIRFIVGTNEETGWADMDYYFEHCELPLPDFGF SPDAEFPIINGEKGNITEYLHFAGKNAGEVVLHSFKAGLAENMVPESATAVISGAKDLQA ALEKFVAEHASKNLRFDLEETAGKATVTLYGKSAHGAMPEKGVNGATYLTLFLNQFNFAD GAAAFIKVGAEKLLEDHEGEKLGTAYVDELMGNTSMNAGVWSFDENSEGKIALNFRFPQG NSPERMQEILAKLDGVVEVELSKHLHVPHYVPMSDPLVSTLIDVYEKHTGLKGYETIIGG GTFGRLLERGVAYGAMFEGEPDSMHQANEMKPVENIYKAAVIYAEAIYELTK > DME ID: DME1003 DME Name: Peroxidase (katG) PDB ID: Not Available MYEKEKCPVTGRTNNAIAGAANSNRDWWPNQLNLKILHQNSNLSNPMALEFNYAEEFKKL DLDALKKDLYALMTDSQDWWPADYGHYGPFFIRMAWHSAGTYRTNDGRGGAGKGTQRFAP LNSWPDNVNLDKARRLLWPIKQKYGSKISWADLMILAGNCALESMGLKTFGFSGGREDVW EPQEDIYWGTESEWLGDNRYSGDRELENPLAAVQMGLIYVNPEGPNGNPDPVASGRDVRE TFARMAMNDEETVALVAGGHTFGKCHGMGDPTLVGPEPEAAGIEEQGLGWKSSFGSGKGG DTISSGIEGAWKPNPTKWDMGYLNMLFKYEWELVKSPAGAHQWLAKDVDEEDMVIDAHDP SKKHRPMMTTADLSLRYDPIYEPISRRYQQNPEEFTDAFARAWFKLTHRDMGPRSRYLGA EVPEEELIWQDPVPAIDHELVDEHDIEDLKSKILASGLSVSQLVSTAWASASTFRGSDKR GGANGARIRLAPQKDWEVNQPAQLNTVLNVLEKIIAEFNSAQTGPKKISLADLIVLGGCA GIEQAAKNAGCNVSVPFIPGRTDASQEQTDVQSFSVLEPIADGFRNYQKTKYSASAEELL VDRAQLLTLTAPEMTVLLGGMRVLNTNHGQSQHGVFTKRPEALTNDFFVNLLDMSTTWKA ISEDENVFEGRDRSTGEIKWTGTSVDLIFGSNSQLRAIAEVYACDDSQSKFINDFVSAWN KVMNADRFDLS > DME ID: DME1004 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MFFFKKSASTFIFLLCLPLNSFASQESNGVEQMRELETSFGGRIGVYILNTKNGKEFSYR QDERFPLCSSFKAFLAASVLKRTQDKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQT LAKAAIQYSDNGASNLLMERYIGGPEGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDT STPKAVAISLNNIAFGSVLDAKNKSLLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGL YGTANDIAILWPDANSPAVMAVYTTRPNQNDKHDETVIKNAAKIAINAVYGSTK > DME ID: DME1005 DME Name: L-arabinose isomerase (araA) PDB ID: 4LQL MRKMQDYKFWFVVGSQPLYGPEALAEVEKDARKLVDGLNKGGKLDYPVEFKLVATTADSI TKFMKEANYNDDVAGVITWMHTFSPAKNWIRGTELLQKPLLHLATQFLNNIPFDSIDMDY MNLHQSAHGDREYAYINSRLNVPAASVYGWWGDADVQEQIADWQHVAVAYNESFHIKIAR FGDTMRDVAVTEGDKVAAQIKLGWTVDYYPTNELVAVVNGIAEDEIDAAYKDLEANYDLV EGDNDHEKYVHNVRYQLREYLGIKKFLDDNGYDAFTDNFQDLEGLEQLPGLAVQLLMIDG YGFGPEGDFKMAGLTRLLKIAADNKQTALMEDYTLDLRHGHEAIMGSHMLEVDPTLASDK PRVEVHPLGIGGKDDPARLVFTGAEGKGYDITLSYFDDGYKFIGYPVDCKTPEAEMPKLP VAKQMWTPEIGLAEGAKQWMKYGGGHHTVLTLALSEEQLEQLARLFKVDFINIK > DME ID: DME1008 DME Name: Tripeptidase (pepT) PDB ID: Not Available MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGY VIGTIPANTDKKVRKIGLLAHLDTADFNAEGVNPQILENYDGESVIKLGDTEFTLDPKDF PNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLNINPDFEHGEIRVGFGPDEEI GVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNTMVNAL QLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQ EIADKMNAELGQNRVKPVIKDQYYNMAQIIEKDMSIIDIAKKAMENLDIVPIIEPIRGGT DGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDTLLEIIRLNNEVVK > DME ID: DME1009 DME Name: Biphenyl dioxygenase (bphC) PDB ID: Not Available MSIRSLGYMGFAVSDVAAWRSFLTQKLGLMEAGTTDNGDLFRIDSRAWRIAVQQGEVDDL AFAGYEVADAAGLAQMADKLKQAGIAVTTGDASLARRRGVTGLITFADPFGLPLEIYYGA SEVFEKPFLPGAAVSGFLTGEQGLGHFVRCVPDSDKALAFYTDVLGFQLSDVIDMKMGPD VTVPVYFLHCNERHHTLAIAAFPLPKRIHHFMLEVASLDDVGFAFDRVDADGLITSTLGR HTNDHMVSFYASTPSGVEVEYGWSARTVDRSWVVVRHDSPSMWGHKSVRDKALRATKHEQ QPE > DME ID: DME1012 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADYNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1013 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MYTHSAGGKFLILFSFDSTAGRWDNFFEAQGKSRERMNAAMWKKRLSALALTAVMAVSIS APALAAETEAPATRDESAAMAAQYAAQYGGAVSVQYAVWQDGEITVSGHAGVYSKSENRV LLDTDLYGIGSVSKMYVTAAVMQLVEQGKINLDAPVTKYLPEFKMADERYKDITVRMLLN HSSGLMSATHNMLLFADDDRSATENLLETLSTQRLAADPGAYSTYCNTGFTLAELVVEAV SGKTFPEYLHEAILAPNSLENTFTPQDEFDTSRLVKTYLGEDPRALPQDCLGTVGTGGIY ANAADLAAFGGLLCSDELLTSASLDAMAAPEYSNGIWPDDADDSLAFGLGWDTVSLAPFG YNDIQALAKGGDTQYYHAALVVLPEYDMAAAVLTSGGVSTYNQMAASRMLIDALAEQGVA VDETVPTLPAATPSQTMPAELMDYSGYYASTLQQFKVDISADGVLTLQSLTVPSAPAQTF YYFDDGSFRDQTGTAAMVKPVVEKNGQTYLWQKAYAFLLGLTVLPTSNYVGQKVEPAQLT EDVQAAWDKWNTTSVLPLNEKYSSQVWLSLGSAAVTELPEYIPGYVGAQKIVDANHTQFA VQVPGNAGRDGSDVTVWEEDGHVWMSAQGLLYADASIAQPIYCGAGAYSTVQPDGYARWY TVGSAAGLTIQVEIEGNGGFYVYDGTGSLAASSVVWGDSTVTLPENGVIAFAGDAGARFH ISVVSAE > DME ID: DME1014 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKFCFLFLIICGLMVFCLQDCQARQKLNLADLENKYNAVIGVYAVDMENGKKICYKPDT RFSYCSTHKVFTAAELLRQKNTSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSAS LRWSDNTAANLILQEIGGVENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQM VKNLQVYIFGDILSDDKKKLLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDI AVIYPPNRKPIVMAIMSRRTEKNAKSDDAMIAEAAKRIFDNLVF > DME ID: DME1015 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MYFCTEIANGVTWIGVNDRKTERFENYIPLPYGVTYNSYFIDDEKTCVIDAVELGSASTF LDKIVECLDGRKLDYIVINHVEPDHSSGLKEVIRTFPTVKIVGNAKTLGMLQAFSPDFPV ENFVTIKEGDILELGNHKLTFAMIPMVHWPESMVTYDLTDKILFSNDAFGSFGALDGGIF DDQVNFEFYQSEMRRYYSNIVGKYGPQVLNAIKKLGGLEIKFICPSHGLIWRKDIAKVVS LYETWAKLEPETEGVVIVYGSMYGNTAKMAEIIGRKLNCCGIKEVKIYDASKTDLSFIIS EIWKYKGLIIGSCAHNNSVYPKIQPLLHKLENYGLKNRYVGIFGSMMWSGGGVRGIQCFA DALKGVEVVGEAVEVKGTPKAEDVTRLEAIAEEMAAKLIAERI > DME ID: DME1016 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTFKECKTGVDRIA APLLDKEGVVIAHKTGSGDVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1017 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKSRKWKKISALLFLGIALLFLLMPTYMQEALIHWFPDISDTYIFPSDTVGKADSCWEWP VARDANRYRMTDDEEAYLEKYGTVAYLVIQDDSIRYEEYREDWTPQKLSNIFSATKSIVG LLVGIAYDEGFIESLDDKVSKYLPEFGEGDKITIRNLLTMSSGLDWDEAYTALISKTTQA YYGDRIRDLIMDLKVVEEPGKKYSYKSGDTQLLSFVLEAALDKVHKEKEYEWGIFKTEVK VHSPVSISEYAERKLWKPLGACNDALWNLDREDGDEKTYCCFNTTARDLARLGRLILNKG NWNGRQLISETYLNEAITPAGYLENEFGDGSLDYYGFQIWIMHYKEMRFPAFRGLGGQYM FVIPQKNAIVIRLGHKRSDEYIREKTIDMDAYLDIAFKILE > DME ID: DME1018 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKANNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLVTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1019 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTKEEMSADHNKAYSNYTSPLGAAMLMNRWFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1020 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKFCFLFLIICGLMVFCLQDCQARQKLNLADLENKYNAVIGVYAVDMENGKKICYKPDT RFSYCSTHKVFTAAELLRQKNTSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSAS LRWSDNTAANLILQEIGGVENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQM VKNLQVYIFGDILSDDKKKLLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDI AVIYPPNRKPIVMAIMSRRTEKNAKSDDAMIAEAAKRIFDNLVF > DME ID: DME1021 DME Name: N-acylhomoserine lactone acylase (lacA) PDB ID: 4YF9; 4YFA; 4YFB; 5C9I MRESIHRGAWPRSVLTLAAVAALAACGGSGGGDGSTYSAEIRRTTMGVPHIKAGNWGSAG YGFGYVQAQDNLCTMADSFLTYRGERSRHLGGSAQLVYNSTLGRPRNIDSDFFHRHVISD EAVDRTMAAQPAKLLQMVEGFAAGYNRYVREAKAGGSAHAACRSEAWVQPITARDVWRRI YAANLAGGYSNFAEAIANAQPPQAKAGAQEPAAFEPGRTRAPSLQVGGELGVGSNMYGFG TAATGEGSGVLFGNPHWYWKGPDRFYQAQLTIDGEANVSGVSFLGLPVIQIGFNDSVAWS HTVSTARRFGFFQLSLVQGEPTSYLRDGVPVKMKPATITVPSRNADGSVSDVTRTLYHSE FGPLVNLAGLNPALAWSQGTAFAIRDINGENFRTLRTWMRWNQAKSLDEFIAIQKEEASI PWVNTVAVGRGSAKAWYADIGAVPNVSPAQTAACTTPFGMAVGQALPNVPFFDGSRSECD WLTDADSVQKGAVGVSRMPSLQRDDYVGNMNDSYWLANVHAPLTGYPAIFGPAGTSAQTL RTRMGHTMALERLAGTDGYAGNKATSAVVREMVLGSRVFSAERFKDEVLDLICTPAQWTV NGAAVDAAQACAVLAAWDNRGRKDSRGSHLWDEFWSRVPTASLFTVPFSAADPLNTPRGI NAAAADALRQAMATAIARVGQSGYALDAPRGEVLYATRGGTRLPLYGGCGAMGYFTITCS ENDITQGGYSMDGQPNASNSYMQVVSFPASGVQAHTFLTFSLSDDPASPHHGDYTKAYSA GQWLRVPFTEAEITGNADYRTATVKE > DME ID: DME1022 DME Name: Tyramine oxidase (tynA) PDB ID: 1D6U; 1D6Y; 1D6Z; 1DYU; 1JRQ; 1LVN; 1OAC; 1QAF; 1QAK; 1QAL; 1SPU; 2W0Q; 2WGQ; 2WO0; 2WOF MGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTLKEFGADVQWDDYAQLF TLIKDGAYVKVKPGAQTAIVNGQPLALQVPVVMKDNKAWVSDTFINDVFQSGLDQTFQVE KRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPR KADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLLDDFASVQNIINNSEEFAAAVK KRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAVVDL EQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGDMIHWRNWDF HLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMG TLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMGQPNVST ERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTR YGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNI GNEQDAAQKFDPGTIRLLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHR LSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHV ARAEEWPIMPTEWVHTLLKPWNFFDETPTLGALKKDK > DME ID: DME1023 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MVMRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL CAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPRRRPATPL PRPAWPRPCASC > DME ID: DME1024 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARG IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR > DME ID: DME1025 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MESALYPIQNKYRFNTLMNGTWQFETDPNSVGLDEGWNKELPDPEEMPVPGTFAELTTKR DRKYYTGDFWYQKDFFIPSFLKKKELYIRFGSVTHRAKVFINGHEVGQHEGGFLPFQVKI SNYINYDQTNRVTVLVNNELSEKAIPCGTEEILDNGQKLAQPYFDFFNYSGIMRNVWLLA LPQSQITNFKLNYQLANNKATITYNIEANNNAEFKVTLFDNQKEVACATSKNTSSLTIKN PHLWSPNDPYSYKIKIEMLEDGKTVDEYTDKIGIRTVKIVNDKILLNNHPIYLKGFGKHE DFNVLGKAVNESIIKRDYECMKWIGANCFRSSHYPYAEEWYQYADKYGFLIIDEVPAVGL NRSITNFLNVTNSNQSHFFASKTVPELKKVHEQEIKEMIDRDQRHPSVIAWSLFNEPEST TQESYDYFKDIFAFARKLDPQNRPYTGTLVMGSGPKVDKLHPLCDFVCLNRYYGWYVAGG PEIVNAKKMLEDELDGWQNLKLNKPFVFTEFGADTLSSSHRLPDEMWSQEYQNEYYQMYF DIFKKYPFICGELVWNFADFKTSEGIMRVGGNDKGIFTRDREPKDIAFTLKKRWQQLN > DME ID: DME1026 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKAYFIAILTLFTCIATVVRAQQMSELENRIDSLLNGKKATVGIAVWTDKGDMLRYNDHV HFPLLSVFKFHVALAVLDKMDKQSISLDSIVSIKASQMPPNTYSPLRKKFPDQDFTITLR ELMQYSISQSDNNACDILIEYAGGIKHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNW STPSAMVRLLRTADEKELFSNKELKDFLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSD RNADGMKTADNDAGLVILPDGRKYYIAAFVMDSYETDEDNANIIARISRMVYDAMR > DME ID: DME1028 DME Name: Chloramphenicolase (chlR) PDB ID: Not Available MKKIDLNSWNRREHFAFFSQFDEPFFSIVAEVDCTVAYRKAKEQDIPFFIWYLYQSLLAA NQVEPFRYRIIDNEVVVLDEIHASSTVAREDHTFGFTFMPYREDIKAFVAEALPEIERVQ QLEGLCFDEKTSRTDVIHYSSIPWINFTALTHARHNARKDSVPKISFGQYQEKEGKLMMP VSVTVHHGLMDGYHVGLFLTKFQKLLES > DME ID: DME1029 DME Name: Glycerol-3-phosphate dehydrogenase (gpsA) PDB ID: Not Available GHEVMMWGRKLDQVVDVHLYHLNEEFFPGVKLNERLDATQNFEDILDSQIILLAVPTGAV EEVCIELNAHLSNPVIIINVAKGLHPTTHELLDHVIKRVIDSNKLKGVVSLIGPSHAEEV VLRKITTINAVSDNPALAEEVQVLFSNDYFRVYTNDDVIGSQYGVAIKNVIALASGIAAG LDAGDNARAALITRGLTEMQRFGVHMGGQPETYLGLCGVGDLVVTATSVHSRNFQAGMEI GQKNSAVGFLDHNTKTVEGVFAAKVVYEIAVEEGIDMPITEQIYKIIYEEKR > DME ID: DME1030 DME Name: Chloramphenicolase (chlR) PDB ID: Not Available MKKIDLNSWNRREHFAFFSQFDEPFFSIVAEVDCTVAYRKAKEQDIPFFIWYLYQSLLAA NQVEPFRYRIIDNEVVVLDEIHASSTVAREDHTFGFTFMPYREDIKAFVAEALPEIERVQ QLEGLCFDEKTSRTDVIHYSSIPWINFTALTHARHNARKDSVPKISFGQYQEKEGKLMMP VSVTVHHGLMDGYHVGLFLTKFQKLLES > DME ID: DME1031 DME Name: Chloramphenicolase (chlR) PDB ID: Not Available MKKIDLNSWNRREHFAFFSQFDEPFFSIVAEVDCTVAYRKAKEQDIPFFIWYLYQSLLAA NQVEPFRYRIIDNEVVVLDEIHASSTVAREDHTFGFTFMPYREDIKAFVAEALPEIERVQ QLEGLCFDEKTSRTDVIHYSSIPWINFTALTHARHNARKDSVPKISFGQYQEKEGKLMMP VSVTVHHGLMDGYHVGLFLTKFQKLLES > DME ID: DME1033 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MMNTRLSCTLALSALLLSSGAQASTPPSAEMRVAEAVKQTIPALMQQQQIPGMAVAVIYQ GTPYYFSYGVADKATRRAVTPQTLFELGSVSKTFTGVLGGYALQRGDIRLQDTVASQWPA LNGPQWRAITLQQLATYTAGGLPLQVPDAVTDTAQLLDFYQRWQPRWAPGTMRSYSNASI GLFGMLAVRPSGMDFSQAMTRWVLQPLGLKHTYFRVPPAAEGEYAWGYREGKALRVSPGM LEQEAYGIKSSAQDMATWLQANLDPAAVTQATLRQALLRAQTRYYQSGEMYQGLGWEMLS WPLQAQTLIDGSDNRVALQPQPVHLIEPPTPPQPASWVHKTGSTNGFGAYIAFIPGSRLG IVMLANKNYPNPARVQAAYTILQQLQ > DME ID: DME1035 DME Name: Cardiac glycoside reductase 1 (cgr1) PDB ID: Not Available MAEEPVVIGDPAPRTRKWPIVVGVVVVVLIAAGAGFWVWHEQPSFCAAICHTPMDEYLET YEQEAGTAGVDKWGNEVANTNAMLAVSHKAQGKDCMACHVPTLSEQMSEGMNWVTGNYVY PLEERDTEMLTEARGVDADEFCLNESCHNLTRDDLIKATSDMEFNPHQPQHGEIECSECH KAHRASVMYCTQCHSEAEVPEGWLTVAEANKLSTAA > DME ID: DME1036 DME Name: Cardiac glycoside reductase 2 (cgr2) PDB ID: Not Available MEYGKCRGIERGMGRRDFLKAATLLGATAAGAGMLAGCAPKSASEAQAQTAPAATGGLDP ADVDWKYETDVVIVGSGSGGTCAAIEAAEAGADVVVFEKDKAMYGGNSALCGGYMLAAGW STQEEITGYAGDTGEAFANQMLRWSQGLGNQDMIREACLRSGEAVDWMMDTGRTYEGASP LPPVWSCGDTEADVVPRSVYNHNAYGATEGHMATLKKRAESLSNIEIEMGCEVAHILKNA EGSVIGVQLADGSFAKARKGVVMACASVDNNLEMSKDLGLMQNVWGLTLEGAGLLAPGNP DMDSNTGDGVRMLREIGAELCMQQAVCMNDSIYVGGISDWGMSEILGKDVNIHDSSNIDA ILVDKTGRRFCQDDAEWGYVMHECAQAAWKQGFTPDDPTTGYIFYVYDATGAPFFEMKGH TPDTCDTTFSADSVDGLAEFIGCDPTALASEVERWNSFCEAGLDADFGRRANMAPIATPP FYCDVVRPGPMGTFAGAKSNVEAEIIGLDGNPIPRLYGAGCIIGGNVSGAFYFGCGWSIT NTVVWGREAGRNVAALEPWE > DME ID: DME1037 DME Name: Dopamine dehydroxylase (dadH) PDB ID: Not Available MGNLTMSRRTFVKTAAITGAAAAAFGASTHTALAEETYSSVSGNDTVAVKTCCRGCGKME CGVKVIVQNGRAIRVEGDEGAFQSMGNCCTKSQSSIQAAYHPDRLHYPMKRTNPKGEEPG WQRISWDEAMQSIVDNFMDIKAKHGGEAIACQVGTSRIWCMHSESILKNMLETPNNVEAW QICKGPRHFATTMVSQFAMSWMETITRPKVYVQWGGASELSNYDDSCRTTVDVASRADVH ISVDPRMANMGKEADYWQHLRPGTDGALALAWTNVIIEKKLYDELYVKKWTNAPFLVCED MEPSGFPTVRTDGSYWDVKTALLKESDIKEGGSPYKFLVYDNNWEKLKAEGVEHEYGAFT WFNADQEGVIDETGGFWEGENYDSEKARQGREAAQDNLLPGQTQGWLPDPMPFDPAIDPA LEGEFEITLKDGKTVKVKPVWEHYKARAAEYKPEVAAEITGIPASEIEAAATAYGTRIDP STGYGNGGIQYMLAVEHFCSAIQNCRAFDNLVGITGNMDTPGGNRGPTIVPIDGDLQGFS AWAPGATTPPEEVNRKQIGIDKFPLLGWWQYWCDSHSLWDAVITGDPYPVRALWNESGNF MSQTNTTRAWEALCSLDFYVDLNLWHTPQNDTADIILPVAHWIELNSPRASQGSAGAMGA TVKCVQPPAEAKYDPEIVMDLARRMNWKWTDEPGNEWPDINWQLDDSIKLLTDDELTYTT WHVENGKPTFERHGVPMAEVTPKYKTWDEYVKAFQEHGWWQAKDIEPRNWGTYRRYQTGA MRARDRVWGRLDYTAGKGIGDWKPGWFTPTMKQEIWSTVMESHHPDHPEWRLPTYTEPPH GPKDGDRIKEYPLTATTGRRIPVYFHSEHRQLPWCRELWPVPRVEINPKTAAEYGIEQGD WVWIETEWGKIREVADLYYGVKEDVINLEHTWWYPEVKDAGHGWQFSQVNQLIDHYAQDP HSGTSNLRAYQVKIYKATPENSPFNNPVPCDSTGTPIIHTSDDPRLKEWLPTYEGRE > DME ID: DME1039 DME Name: Molybdopterin-dependent enzyme (molD) PDB ID: Not Available MATFTPGFHGHRRTRGGRLPPGQFLTEDFPVLSAGPTPDIPLDRWEFTLTAESGERRRWN WQEFSALPQQEVTTDLHCVTRWSKFDTRWRGVSLDTLLNGVTTDARHALAECHGGYTTNL PLTDLRGGKAWIAHTYDGEPLTAEHGGPARLLVPHLYFWKSAKWISGITLRAEDHRGFWE QLGYHDHGDPWREQRTWND > DME ID: DME1040 DME Name: Molybdopterin-dependent enzyme (molD) PDB ID: Not Available MTLARLALSGDLVRPSRLTVPDLLRWPQHRVAVSFECATSGTQHHRFTGPRLYDVLADAG PGFDPVRRKDRLRFLIAVTGTDGHHALLSWAEIDPDFADAPVLLGVSIDDTPLDAAGPQL VLPQDRCGARHISQITAIRVDGSYRCAPVEVAAVP > DME ID: DME1041 DME Name: NADH dehydrogenase (nuoE) PDB ID: Not Available MTDGQTSLGMPQLPAPDYPAEVRARLEADAEEIIARYPGSRSALLPLLHLVQSEEGHVTR TGMKFCAEILGLTTAEVTAVATFYTMYRRKPSGDYQVGVCTNTLCAVMGGDAIFEELKEH LGVGNNETTEDGKVTLEHIECNAACDFAPVVMVNWEFFDNQTPDSAKKIVDDLRAGRPVE PTRGAPLCTYKETARILAGFPDEREGAVEATGGAGPASLVGLRLAKGETPHHKIVHPRGE SASGEGE > DME ID: DME1042 DME Name: Beta-glucuronidase (uidA) PDB ID: 6ECA METSLLYPVTNDQRTDQKLDGLWQFKFDEAGEGEKSGWETGFHDGVSMPVPASFNDFFTD KASREYTGDFWYSRNFFVPSAAKGKALFLRFDAVTHRATIFVNGKEIRTHEGGFLPFAAD ISEAVKYGAENTVVVKGNNELSREALPAGDTITLRNGKKMVRPFFDFYNYSGLNRSVHLL SLPQERVLDYTTTFALAGNDATVNYTVETNGDAPVTVSLADADGQVVATAQGKQGALQVQ NAHLWQVRNAYLYTLTIQLGDDTQTPLDTYTDRIGIRTIKISGTDILVNDKPIYLKGFGR HEDSPFAGRAFDLNVEKKDFALMKWIGANSFRTSHYPYDEQVYKIADEEGFLLTDEVPAV GFKMAAAAFLGGLNQSFFKGPWLKKLHERHIDQIRDLIKRDKNHPSVLAWSLFNEPDTID ENAVPYFKQIFDESKDLDPQGRPRTFTLSEDDTIETSKVLDFPDFYMLNRYPGWYHFGGY QISDGEAGLRDEMDKWQKAGVKKPVVFTEFGADTEAGLHKLPSVMWTEEYQVEVLKMFSR VFDDYDFIKGEQVWNLADFQTVEGNMRVNGNKKGIFTRDRQPKAAAFFYHDRWNKLPLDY KAK > DME ID: DME1043 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MTQQQLYTPKGFPKNFLWGGAIAANQAEGAWQTDGRGPSQADIMLLPEKYSRLGSFGEHV TRADIERALADKSGNYPRRRGIDFFHTYDSDLDLMKEMGFNTFRTSFSWSRIFPNGDEKE PNEKGLKFYDKLIQKMLDLDITPVMTISHYEMPLNLITKYGGWENPEMINFFNRFAQVLL DRYHDKVKYWIVFNQVNDVYGWGEFAGLGILKENQPNEKQAKFQAVHHQFIANAQTVKYG HQIDNDIKIGMMLGLTNVYPASTKPQDVMATYKRWNKDTFFFSDVLARGEYPGYMLRYFE DNNIQLSIDQKELDLIKNNPVDFIAFSYYSSSLISADTPDSLLPNPELEESIWGWSFDPI GFRYGFNVLWDRYHLPLFVAENGLGALDTVEDNKIHDAYRIKYLKAHIKQMKEAIKDGVH IFGYAAWGPIDIVSYSQAEMSKRYGFVYVDLDDKGNGTGKRIRKDSFYWYQKVIESNGDQ I > DME ID: DME1044 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MTQQQLYTPKGFPKNFLWGGAIAANQAEGAWQTDGRGPSQADIMLLPEKYSRLGSFGEHV TRADIERALADKSGNYPRRRGIDFFHTYDSDLDLMKEMGFNTFRTSFSWSRIFPNGDEKE PNEKGLKFYDKLIQKMLDLDITPVMTISHYEMPLNLITKYGGWENPEMINFFNRFAQVLL DRYHDKVKYWIVFNQVNDVYGWGEFAGLGILKENQPNEKQAKFQAVHHQFIANAQTVKYG HQIDNDIKIGMMLGLTNVYPASTKPQDVMATYKRWNKDTFFFSDVLARGEYPGYMLRYFE DNNIQLSIDQKELDLIKNNPVDFIAFSYYSSSLISADTPDSLLPNPELEESIWGWSFDPI GFRYGFNVLWDRYHLPLFVAENGLGALDTVEDNKIHDAYRIKYLKAHIKQMKEAIKDGVH IFGYAAWGPIDIVSYSQAEMSKRYGFVYVDLDDKGNGTGKRIRKDSFYWYQKVIESNGDQ I > DME ID: DME1045 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MLFRWCPLVALAIASGTAATEQSWESPPYYPSPWTKGEGEWEDAYQKAVSFVSQLTLAEK VNLTTGVGWMQESCVGQVGSIPRLGFRSLCMQDGPLGIRFGDYVTAFPAGINVAATWSRE LAYLRGKAMGEEFHGKGADVILGPAIGPIGRAPEGGRNWEGFGPDPVLAGRLVAETIKGM QKTGVIACAKHFIANEQERFRIAAEAQGYGFDIAESISSNVDDVTMHEIYLWPFADAVKA GVGSIMCSYNQINNSYGCGNSYTQNKLLKGELGFRGFIMSDWQAHHSGVGSAFAGLDMSM PGDTLFGTGVSFWGANLTIAVANGTIPEWRVDDMAVRIMAAYYKVGRDKVQVPINFNSWT TDVEGYQHALVKEGYGVVNQRVNVRDHHARIARRMASDSIVLLKNEGVLPLTGTEQFTAI IGEDAGPNINGPNSCPDRGCDNGTLAMGWGSGTTNFPYLVTPDDAIQREIVAKGVGNVMS VLQNGDFKNIQSVAGQANVALVFINSDSGEGYISVDGNEGDRKNLTTWKGGDEMVKQVTS VCNNTVLVIHSSGPILAGQWHDNPNITAILWAGLPGQESGNALVDVLYGKVNPGGKSPFT WGRTAEDYGTTILREPNNGKGAPQHQFSEGIMFEYRHFDQQNITPVYEFGYGLSYTTFSY SNLRVRPMRANKYVPATGMTKPAPRLGHSSTKYADYLFPGGFKGVTKYVYPWLTSTDPKE ASGDKNYGMPLEDYVPPNANNGDAQPVLPASGVPGGNPGLFEDLYKVSAVITNDGDRVGE EVPQLYISLGGDRNAKVVLRGFDRIRLAPRQRFRWRTTITRRDISNWDPASQDWVMTEHP KIVYVGSSSRNLPLQAPLPPPNLA > DME ID: DME1047 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MLFRWCPLVALAIASGTAATESWESPPYYPSPWTKGEGEWEAAYQKAVSFVSQLTLAEKV NLTTGVGWMQESCVGQVGSIPRLGFRSLCMQDGPLGIRFGDYVTAFPAGINVAATWSREL AYLRGKAMGEEFRGKGADVILGPAIGPIGRAPEGGRNWEGLGPDPVLAGKLVAETIKGMQ KSGVIACAKHFIANEQERFRIAAEAQGYGFDIAESISSNVDDVTMHEIYLWPFADAVKAG VGSIMCSYNQINNSYGCGNSYTQNKLLKGELGFRGFIMSDWQAHHSGVGSAFAGLDMSMP GDTLFGTGVSYWGANLTIAVANGTIPEWRVDDMAVRIMAAYYKVGRDQVQVPINFNSWTT DVEGYQHALVKEGYGVVNQRVNVRDHHAQIARRVARDSTVLLKNEGVLPLTGTEQFTAII GEDAGPNINGPNSCPDRGCDNGTLAMGWGSGTTNFPYLVTPDDAIQREIVGKGVGNVMSV LQNGDFKNIQSVAGQADVALVFINSDSGEGYISVDGNEGDRKNLTTWKGGDEMVKQVTSV CNNTVLVIHSSGPILAGEWHDNPNITAILWAGLPGQESGNALVDILYGKENPGGKSPFTW ARTAEDYGTTILREPNNGKGAPQHLFSEGIMFEYRHFDQKNITPVYEFGYGLSYTTFSYS NLKVRPMRANKYVPATGMTKPAPRLGHSSTKYADYLFPGGFKGVTKYVYSWLTSTDPKEA SGDKNYGMPLEDYVPPNANNGDAQPVLPASGVPGGNPGLFEDLYEVSAVITNDGDRVGEE VPQLYISLGGDRNAKVVLRGFDRIRLAPHQRFRWRTTITRRDVSNWDPASQDWVMTENPK IVYVGSSSRNLPLQAPLPAPNLA > DME ID: DME1048 DME Name: Oxygen-insensitive NADPH nitroreductase B (nfsB) PDB ID: 1DS7; 1ICR; 1ICU; 1ICV; 1IDT; 1OO5; 1OO6; 1OON; 1OOQ; 1YKI; 1YLR; 1YLU; 3X21; 3X22 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV > DME ID: DME1049 DME Name: Dihydrofolate reductase (folA) PDB ID: 1DDR; 1DDS; 1DHI; 1DHJ; 1DRA; 1DRB; 1DRE; 1DRH; 1DYH; 1DYI; 1DYJ; 1JOL; 1JOM; 1RA1; 1RA2; 1RA3; 1RA8; 1RA9; 1RB2; 1RB3; 1RC4; 1RD7; 1RE7; 1RF7; 1RG7; 1RH3; 1RX1; 1RX2; 1RX3; 1RX4; 1RX5; 1RX6; 1RX7; 1RX8; 1RX9; 1TDR; 2ANO; 2ANQ; 2D0K; 2DRC; 2INQ; 3DAU; 3DRC; 3K74; 3KFY; 3OCH; 3QL3; 3QYL; 3QYO; 3R33; 4DFR; 4EIG; 4EIZ; 4EJ1; 4FHB; 4GH8; 4I13; 4I1N; 4KJJ; 4KJK; 4KJL; 4NX6; 4NX7; 4PDJ; 4X5F; 4X5G; 4X5H; 4X5I; 4X5J; 5CC9; 5CCC; 5DFR; 5E8Q; 5EAJ; 5UIH; 5UII; 5UIO; 5UIP; 5UJX; 5W3Q; 5Z6F; 5Z6J; 5Z6K; 5Z6L; 5Z6M; 6CQA; 6DFR; 6MR9; 6MT8; 6MTH; 7DFR MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR > DME ID: DME1050 DME Name: Dihydrofolate reductase (folA) PDB ID: 1AO8; 1BZF; 1DIS; 1DIU; 1LUD; 2HM9; 2HQP; 2L28; 2LF1; 3DFR MTAFLWAQDRDGLIGKDGHLPWHLPDDLHYFRAQTVGKIMVVGRRTYESFPKRPLPERTN VVLTHQEDYQAQGAVVVHDVAAVFAYAKQHPDQELVIAGGAQIFTAFKDDVDTLLVTRLA GSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHTYEVWQKKA > DME ID: DME1051 DME Name: Dihydrofolate reductase (folA) PDB ID: Not Available MIQATGIVAIDPRGVMGGAGKLPWNYPEDLRFFSETIQDHPIIMGRKTWESLPDRYKCGR TVIVFSRQHSCAQGIWISSLVEYEKLSLNSPFLIGGAELFDWFFQYNLLKSCFVTHIKRE YQGDTFFPVERLSGWKRESVLKTEDFNIYHYENYANQNP > DME ID: DME1052 DME Name: Glyceraldehyde-3-phosphate dehydrogenase (gap) PDB ID: Not Available MTVKIGINGFGRIGRLAFRRIMDLGEKTKDIEVVAINDLTTPAMLAYLLKYDTTHGTFNH EVSSTDDSIVVDGKKYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAK RVLISAPAGNDLKTIVYSVNENTLTADDKIVSAASCTTNSLAPMANALDKEFGIEVATMT TIHAYTGTQMTLDGPSRSGKEQDARAAAENIIPHTTGSAKAIGLVLPNLNGKMNGHAQRV PVPDGSETELVSILKKKVTADEVNEAMKKYESPSFAYNGDHIVSSDVINMTAGSIFDPTQ TMVTTAGDKQLVKTVAWYDNEYSFTCQMVRTLLHFATL > DME ID: DME1053 DME Name: L-arabinose isomerase (araA) PDB ID: Not Available MLNTENYEFWFVTGSQSLYGEETLRSVEKDAKEIVEKLNASHQLPYPIVFKLVATTADNI TKVMKEANYNDHVAGVITWMHTFSPAKNWIRGTKLLQKPLLHLATQFLNKIPYDTIDFDY MNLNQSAHGDREYAFINARLRKNNKIISGYWGDEDVQKAMAKWMDVAVAYNESFKIKVVT FADKMRNVAVTDGDKVEAQIKFGWTVDYWGVGDLVAEVNAVSEADIDAKYADLQKEYDFV EGQNTPEKFEHNVKYQIREYFGLKKFMDDRGYTAFTTNFEDLVGLEQLPGLAAQLLMAEG YGFAGEGDWKTAALDRLLKIMAHNEKTVFMEDYTLDLRQGHEAILGSHMLEVDPSIASDK PRVEVHPLDIGDKDDPARLVFTGMQGDAVDVTMADYGDEFKLMSYDVRGNKPEADTPHLP VAKQLWTPKQGLREGAVGWLTVGGGHHTVLSFAVDSEQLQDLSHLFDLTYVNIK > DME ID: DME1054 DME Name: L-arabinose isomerase (araA) PDB ID: Not Available MIKSKEYKFWFCTGSQDLYGEECLAHVAEHSRRIVEALNASGALPYEVVWKPTLITNELI RKTFNEANTDETCAGVITWMHTFSPAKSWILGLQEYRKPLLHLHTQFNEEIPYDTIDMDF MNENQAAHGDREYGHIFSRLRMERKVVAGYWADPKVQKKIGSWMRTAVGVIESSHVRVMR IADNMRNVAVTEGDKVEAQIKFGWEVDTYPVNEIAEAVAEVSKSDIGTLVEEYYDKYDIL LEGRDEKEFREHVAVQAGIEIGFERFLEERDYQAIVTHFGDLGSLKQLPGLAIQRLMEKG YGFGGEGDWKTAAMVRIMKIMTEGVKDARGTSFMEDYTYNLIPGKEGILQAHMLEVCPSV AEGPISIKCQPLTMGDREDPARLVFTSKEGPAVAASLIDLGDRFRLIINDVDCKKTEKPM PKLPVATAFWTPQPDLQTGAEAWILAGGAHHTAFSYDLSAGQLGDWADAMGIEAVYIDKN TEIRQFKNELRWNAAAYKLGI > DME ID: DME1055 DME Name: Cytidine deaminase (cdd) PDB ID: 1AF2; 1ALN; 1CTT; 1CTU MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLA AACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALA AITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQ DHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPL QGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHSIDRVLLA > DME ID: DME1056 DME Name: Cytidine deaminase (cdd) PDB ID: 6K63 MHSRFQAALTTLAADLQAAIAPMLADPHFPALLEADQVATLQHATGLDEDALAFALLPLA AACARPDLSHFNVGAIARGVSGRWYFGGNMEFLGATMQQTVHAEQSAISHAWLRGETSLR AITVNYTPCGHCRQFMNELNSGLALRIHLPGREAHALEHYLPDAFGPKDLEIKTLLMDEQ DHGFPVSGDALTQAAIQAANRCHAPYSHSPSGVALELKDGTIFSGSYAENAAFNPTLPPL QGALNLLSLNGYDYPAIQRAILAEKADAALIQWDATVATLKALGCHNIERVLLG > DME ID: DME1057 DME Name: Catechol-2,3-dioxygenase (caD) PDB ID: Not Available MSNFDVAQLAHVELYSPKPEETLKFFTDYLGLQISAREGQSVYLRAYEDFYHHTLKITEA KEAGMAHTAWRASSEAALYQRVQSLEKSGYGKGWIEGDLGHGAAYQFQTPDGHNMEILWN VEYYRAPEDQKTMLKSRPQKRPNIGIPARRLDHINLMCGNVTQNKQFMADELGFKLRENI IMNDGAEMGAWMSVSPLVHEIALMGDQSGEKGRFHHVAYWYGYPQHLMDLADLLVENGIE IEAGPGKHGISQAYFMYVFEPGGNRVELFGDSGYLILDPDWKTITWKEEELDKGIIWYGS PLPQEYFIYGTPDRSSVKVK > DME ID: DME1058 DME Name: Propanediol dehydrogenase (dhaT) PDB ID: Not Available MAERSYDFLMPSVNFFGPGVISKIGDRAKMLGMKKPVIVTDKFLEGLKDGAVEQTLDSLK AAGVDYVVYNNVEPNPKIRNIKEVKKLYEESGADSIITVGGGSAHDTGKGAGIILTNGDD ITKLAGIETLDKALPPLIAVNTTAGTGSELTRHAVITNEETHLKFVVVSWRNIPLVSFND PTLMLDVPKGLTAATGMDAFVQAVEPYVSVDHNPITDSQCVEAIKLIETSLREAVANGHN LDARTKMVEAEMLAGMAFNNANLGYVHAMAHQLGGQYDAPHGVCCALLLPYVEEYNIIAC PDRFAQLAEIMGENTEGLSTRDAAELAIKAMKQLSEDVGIPHSIKEIGAKPEDFELMAEN ALKDGNAFSNPRKGTKEDIIKIFQAAYDAE > DME ID: DME1059 DME Name: Fumarate reductase flavoprotein (frdA) PDB ID: 1E7P; 1QLB; 2BS2; 2BS3; 2BS4 MKVQYCDSLVIGGGLAGLRAAVATQQKGLSTIVLSLIPVKRSHSAAAQGGMQASLGNSKM SDGDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWTRIHKGDRMAIIN AQKTTITEEDFRHGLIHSRDFGGTKKWRTCYTADATGHTMLFAVANECLKLGVSIQDRKE AIALIHQDGKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKNTTNAVVCEGTGTAIA LETGIAQLGNMEAVQFHPTPLFPSGILLTEGCRGDGGILRDVDGHRFMPDYEPEKKELAS RDVVSRRMIEHIRKGKGVQSPYGQHLWLDISILGRKHIETNLRDVQEICEYFAGIDPAEK WAPVLPMQHYSMGGIRTDYRGEAKLKGLFSAGEAACWDMHGFNRLGGNSVSEAVVAGMIV GEYFAEHCANTQVDLETKTLEKFVKGQEAYMKSLVESKGTEDVFKIKNRMKDVMDDNVGI FRDGPHLEKAVKELEELYKKSKNVGIKNKRLHANPELEEAYRVPMMLKVALCVAKGALDR TESRGAHNREDYPKRDDINWLNRTLASWPNPEQTLPTLEYEALDVNEMEIAPGYRGYGAK GNYIENPLSVKRQEEIDKIQSELEAAGKDRHAIQEALMPYELPAKYKARNERLGDK > DME ID: DME1061 DME Name: Tyrosine decarboxylase (tdc) PDB ID: Not Available MKNEKLAKGEMNLNALFIGDKAENGQLYKDLLIDLVDEHLGWRQNYMPQDMPVISSQERT SESYEKTVNHMKDVLNEISSRMRTHSVPWHTAGRYWGHMNSETLMPSLLAYNFAMLWNGN NVAYESSPATSQMEEEVGHEFAHLMSYKNGWGHIVADGSLANLEGLWYARNIKSLPFAMK EVKPELVAGKSDWELLNMPTKEIMDLLESAEDEIDEIKAHSARSGKHLQAIGKWLVPQTK HYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIVRGLAEEQIPVLGVVGVVGSTEE GAVDSIDKIIALRDELMKDGIYYYVHVDAAYGGYGRAIFLDEDNNFIPYEDLQDVHEEYG VFKEKKEHISREVYDAYKAIELAESVTIDPHKMGYIPYSAGGIVIQDIRMRDVISYFATY VFEKGADIPALLGAYILEGSKAGATAASVWAAHHVLPLNVAGYGKLIGASIEGSHHFYNF LNDLTFKVGDKEIEVHTLTHPDFNMVDYVFKEKGNDDLVAMNKLNHDVYDYASYVKGNIY NNEFITSHTDFAIPDYGNSPLKFVNSLGFSDEEWNRAGKVTVLRAAVMTPYMNDKEEFDV YAPKIQAALQEKLEQIYDVK > DME ID: DME1063 DME Name: Nitroreductase (NTR) PDB ID: Not Available MKKGARMSETLNVVTLLGSLRKGSFNGMVARTLPKVAPAGMTVSPLPSIGDIPLYDADIQ QEEGFPASVEALAEQIRNADGVVIVTPEYNYSVPGGLKNAIDWLSRLPEQPLAGKPVLIQ TSSMGAIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQTGEVVDQGTLDHLTG QLTAFGEFIQRVKA > DME ID: DME1064 DME Name: Nitroreductase (NTR) PDB ID: Not Available MPPICDAILRRRAIKQYTKESVSIEAIEYLRKVAVAIPTGHNTRHTEFAFVTNPRIIKTI SQAKGEKAEYMQHAKLLIVVMGIQNDGVTSIATDMSIAAAMIQLACSDFGLACSWEQFYG RKNVYGEDSERIVLDVLRLLNSPNRRVLCALAIGYPAVQMPPADMHENGRIYMIE > DME ID: DME1065 DME Name: Nitroreductase (NTR) PDB ID: Not Available MTSVFECIERRRTIRHYDQNWVCPKEHLEAIVNAALKSPTACNRQSIDLLVITNKEVLDK IGEVGLNTLKKGTKEHMEERKHEGYKNVFTCDAPVLFLLVKNDRVNPLYTDVDAGIMCES IMLTAASYGYGTMCIGVLRATDLYEAVGIHKEDLAMAVCMGKIEDGYVPPEKPIKCKATY IE > DME ID: DME1066 DME Name: Nitroreductase (NTR) PDB ID: Not Available MNMDLFYDRRSVRSYTGEKISEEDIDKIVRAGFYAPTAVNKQETEFIIIREKSLLENITK IHPYSSMLKSSSHAIVVCANLKKAYTPEYWVCDASAATENILLAAHMLGYGAVWLGVYPE KDRMESIKKLLQLPEQVEILSIVSIGVSKVQPVNRPERFDATRLHNDKW > DME ID: DME1068 DME Name: Aminoglycoside O-phosphotransferase (aphA6) PDB ID: 1P40 MELPNIIQQFIGNSVLEPNKIGQSPSDVYSFNRNNETFFLKRSSTLYTETTYSVSREAKM LSWLSEKLKVPELIMTFQDEQFEFMITKAINAKPISALFLTDQELLAIYKEALNLLNSIA IIDCPFISNIDHRLKESKFFIDNQLLDDIDQDDFDTELWGDHKTYLSLWNELTETRVEER LVFSHGDITDSNIFIDKFNEIYFLDLGRAGLADEFVDISFVERCLREDASEETAKIFLKH LKNDRPDKRNYFLKLDELN > DME ID: DME1069 DME Name: Nicotinate dehydrogenase (nicA) PDB ID: Not Available MQTTISLQVNGQPVEVSAMPDTPLLLILRNDLCLNGPKYGCGLGECGACTVIIDGVAARS CVIPLAGAAGRNITTLEGLGSKAAPHPVQQAFIDEQAAQCGYCMNGMIMTAKALLDRIPE PSDEQIRNELSANLCRCGTHVEILRAVRRAAETRRKP > DME ID: DME1070 DME Name: Nitroreductase (NTR) PDB ID: Not Available MKITEALKARRSYYAINRELPVAIDRVMDMVKELTELVPDAFNMKSSRVAVVHGEKQDQL WNKIYDVFEGKVAREKIDSFRAGSGTILYFYDRKVVESLQKQYPLYADNFPVWASQSSAM LQLAVWSGLRELNIGASLQHYNPVIDNAVKELLHLSGDYVLVAEMPFGGIVEEPAPKDKE EIEKRVFSAC > DME ID: DME1072 DME Name: Cytochrome P450 MEG (cyp106) PDB ID: 4YT3; 5IKI; 5XNT MKEVIAVKEITRFKTRTEEFSPYAWCKRMLENDPVSYHEGTDTWNVFKYEDVKRVLSDYK HFSSVRKRTTISVGTDSEEGSVPEKIQITESDPPDHRKRRSLLAAAFTPRSLQNWEPRIQ EIADELIGQMDGGTEIDIVASLASPLPIIVMADLMGVPSKDRLLFKKWVDTLFLPFDREK QEEVDKLKQVAAKEYYQYLYPIVVQKRLNPADDIISDLLKSEVDGEMFTDDEVVRTTMLI LGAGVETTSHLLANSFYSLLYDDKEVYQELHENLDLVPQAVEEMLRFRFNLIKLDRTVKE DNDLLGVELKEGDSVVVWMSAANMDEEMFEDPFTLNIHRPNNKKHLTFGNGPHFCLGAPL ARLEAKIALTAFLKKFKHIEAVPSFQLEENLTDSATGQTLTSLPLKASRM > DME ID: DME1075 DME Name: Cytochrome P450 102A1 (cyp102) PDB ID: 1BU7; 1BVY; 1FAG; 1FAH; 1JME; 1JPZ; 1P0V; 1P0W; 1P0X; 1SMI; 1SMJ; 1YQO; 1YQP; 1ZO4; 1ZO9; 1ZOA; 2BMH; 2HPD; 2IJ2; 2IJ3; 2IJ4; 2J1M; 2J4S; 2NNB; 2UWH; 2X7Y; 2X80; 3BEN; 3CBD; 3DGI; 3EKB; 3EKD; 3EKF; 3HF2; 3KX3; 3KX4; 3KX5; 3M4V; 3NPL; 3PSX; 3WSP; 4DQK; 4DQL; 4DTW; 4DTY; 4DTZ; 4DU2; 4DUA; 4DUB; 4DUC; 4DUD; 4DUE; 4DUF; 4H23; 4H24; 4HGF; 4HGG; 4HGH; 4HGI; 4HGJ; 4KEW; 4KEY; 4KF0; 4KF2; 4KPA; 4KPB; 4O4P; 4RSN; 4WG2; 4ZF6; 4ZF8; 4ZFA; 4ZFB; 5B2U; 5B2V; 5B2W; 5B2X; 5B2Y; 5DYP; 5DYZ; 5E78; 5E7Y; 5E9Z; 5JQ2; 5JQU; 5JQV; 5JTD; 5OG9; 5UCW; 5XA3; 5XHJ; 5ZIS; 5ZLH; 6H1O; 6H1S; 6IAO MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIK EACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMM VDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVR ALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLN GKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLV DPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQ LHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLK HFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHN TPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGH PPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIAD RGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMH GAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFG LDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVE LEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDE KQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLI MVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIIT LHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYAD VHQVSEADARLWLQQLEEKGRYAKDVWAG > DME ID: DME1076 DME Name: Nicotinamidase (pncA) PDB ID: 2WT9; 2WTA MKMNKQPQNSALVVVDVQNGFTPGGNLAVADADTIIPTINQLAGCFENVVLTQDWHPDNH ISFAANHPGKQPFETIELDYGSQVLWPKHCIQGTHDAEFHPDLNIPTAQLIIRKGFHAHI DSYSAFMEADHTTMTGLTGYLKERGIDTVYVVGIATDFCVAWTALDAVKQGFKTLVIEDA CKGIDLNGSLEQAWQTMQQQGVVRIQSTDLLNEC > DME ID: DME1077 DME Name: NADPH-dependent curcumin reductase (curA) PDB ID: Not Available MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSD EPSYSPPVDIGGVMVGGTVSRVVESNHPDYQSGDWVLGYSGWQDYDISSGDDLVKLGDHP QNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGV AGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHRIHEFQREMG QWVKEDKIHYREEITDGLENAPQTFIGLLKGKNFGKVVIRVAGDD > DME ID: DME1080 DME Name: Azoreductase (azoR) PDB ID: Not Available MKFVGLVGANYDQSYNRKLLEFIRRHFKIKFELEVLEIDEVPMFNQDEKWDESFQLRLLN NKITRADGVIIATPEHNHTISAALKSVLEWLSFEVHPFENKPVMIVGASYYDQGTSRAQV HLRKILEAPGVNAYTLPGNEFLLGKAKEAFDLEGNITNEGTINFLEQCLDNFIQYVGVVS KLKKPKPIEPEDLDCNNPIATTVTEVDPDDPEWVEKVAEITGAVSGDTYVKLDHGILTVN QIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMFAKRVPPQSGSRMSTVHGSLPPARM KNVEWVIGTLRNGNQEYVRTIVPGSPEGVINTHNYQAMYYDDGSYAGINEIVFNFKPWLD WYLETTGQRLVGGSGPFAPAAASHGGSDATSGASDAGGHGGDAAPAADATSGASSY > DME ID: DME1081 DME Name: Azoreductase (azoR) PDB ID: Not Available MKNVLVVKANNRPDGVSAKMFDTFVENLDRTAVDVVTFDVYAQPMPYIGQTLFEAFGKLA QEQDLNQEEQELMTVRQDVMNKFAAADTIVFAFPMWNLTIPAALHTFIDYIFQAGFTFSY NEDGSMNQLLKDKEVVLLNARGGVYSGEMSGMESAVTFMEKVFGGMFGMTISDEVIIEGH NADPSKTEEIIAAGLEKVAEAAKKF > DME ID: DME1082 DME Name: Azoreductase (azoR) PDB ID: Not Available MDRKGFLKSTMIATGSLLLGGAGICRFLNDKEPADGPFPRTIEKIHCGNMKKVLVIMSAG TKLGNTDRLTDAYIKGLVERGHSVTKVYLGSMRIEGCRGCGVCQRLAHQCAVRDGMQDIY PLFAECDTVVMASPLYFWTITSQLKAFIDRLYAISADDKYPQKDTVLLMTAGDDNENTFD QPKQYFRLLSQALGWNEVGIYCAGGCTGCEKLARQIDKVHLENVYKMGLEL > DME ID: DME1083 DME Name: Azoreductase (azoR) PDB ID: Not Available MDRKGFLKSTMIATGSLLLGGAGICRFLNDKEPADGPFPRTIEKIHCGNMKKVLVIMSAG TKLGNTDRLTDAYIKGLVERGHSVTKVYLGSMRIEGCRGCGVCQRLAHQCAVRDGMQDIY PLFAECDTVVMASPLYFWTITSQLKAFIDRLYAISADDKYPQKDTVLLMTAGDDNENTFD QPKQYFRLLSQALGWNEVGIYCAGGCTGCEKLARQIDKVHLENVYKMGLEL > DME ID: DME1085 DME Name: VanA ligase (vanA) PDB ID: Not Available MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGITKSGVWKMCEKPCAEWE NDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFV GCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVAATFTYPVFVKPARSGSSFG VKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIRLQYGI FRIHQEVEPEKGSENAVITVPADLSAEERGRIQETAKKIYKALGCRGLARVDMFLQDNGR IVLNEVNTLPGFTSYSRYPRMMAAAGIALPELIDRLIVLALKG > DME ID: DME1086 DME Name: VanA ligase (vanA) PDB ID: 1E4E MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGITKSGVWKMCEKPCAEWE NDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFV GCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVAATFTYPVFVKPARSGSSFG VKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIRLQYGI FRIHQEVEPEKGSENAVITVPADLSAEERGRIQETAKKIYKALGCRGLARVDMFLQDNGR IVLNEVNTLPGFTSYSRYPRMMAAAGIALPELIDRLIVLALKG > DME ID: DME1087 DME Name: Hydroxybenzoate 3-monooxygenase (pobA) PDB ID: 1D7L; 1DOB; 1DOC; 1DOD; 1DOE; 1IUS; 1IUT; 1IUU; 1IUV; 1IUW; 1IUX; 1K0I; 1K0J; 1K0L; 1PXA MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAG VDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREACGATT VYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERV YPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLSEKVEDWSDERFW TELKARLPSEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLN LAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFS QRIQQTELEYYLGSEAGLATIAENYVGLPYEEIE > DME ID: DME1088 DME Name: Hydroxybenzoate 3-monooxygenase (pobA) PDB ID: 1BF3; 1BGJ; 1BGN; 1BKW; 1CC4; 1CC6; 1CJ2; 1CJ3; 1CJ4; 1PBB; 1PBC; 1PBD; 1PBE; 1PBF; 1PDH MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAG VDRRMARDGLVHEGVEIAFAGQRRRIDLKRLSGGKTVTVYGQTEVTRDLMEAREACGATT VYQAAEVRLHDLQGERPYVTFERDGERLRLDCDYIAGCDGFHGISRQSIPAERLKVFERV YPFGWLGLLADTPPVSHELIYANHPRGFALCSQRSATRSRYYVQVPLTEKVEDWSDERFW TELKARLPAEVAEKLVTGPSLEKSIAPLRSFVVEPMQHGRLFLAGDAAHIVPPTGAKGLN LAASDVSTLYRLLLKAYREGRGELLERYSAICLRRIWKAERFSWWMTSVLHRFPDTDAFS QRIQQTELEYYLGSEAGLATIAENYVGLPYEEIE > DME ID: DME1089 DME Name: Hydroxybenzoate 3-monooxygenase (pobA) PDB ID: 6DLL MKTQVAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQGTVDLLREAG VAERMDREGLVHEGVELLVGGRRQRLDLKALTGGKTVMVYGQTEVTRDLMQAREASGAPI IYSAANVQPHELKGEKPYLTFEKDGRVQRIDCDYIAGCDGFHGISRQSIPEGVLKQYERV YPFGWLGLLSDTPPVNHELIYAHHERGFALCSQRSQTRSRYYLQVPLQDRVEEWSDERFW DELKARLPAEVAADLVTGPALEKSIAPLRSLVVEPMQYGHLFLVGDAAHIVPPTGAKGLN LAASDVNYLYRILVKVYHEGRVDLLAQYSPLALRRVWKGERFSWFMTQLLHDFGSHKDAW DQKMQEADREYFLTSPAGLVNIAENYVGLPFEEVA > DME ID: DME1090 DME Name: Aminoglycoside phosphotransferase (aph-Ib) PDB ID: Not Available MIDLDVEIYQHLNEQIKINKLCYLSSGDDSDTFLCNEQYVVKVPKRDSVRFAQKREFELY RFLENCNLSYQTPAVVYQSDRFNIMKYIKGERITYEQYHKLSEKEKDALAYDEATFLKEL HSIEIDCSVSLFSDALVNKKDKFLQDKKLLISILEKEQLLTDEMLEHIETIYENISSNAV IFNYIPCLVHNDFSANNLIFRNNRLFGVIDFGDFNVGDPDNDFLCLLDCSTDDFGKEFGR KVLKYYQHKAPEVAERKAELNDVYWSIDQIIYGYERKDREMLIKGVSELLQTQAEMFIF > DME ID: DME1091 DME Name: Kanamycin/gentamycin-resistance enzyme (aacA) PDB ID: Not Available MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLESLKKHYTEPWEDEVFR VIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLI FEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYD DNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKE KAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKR DIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNA TTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTN FGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD > DME ID: DME1092 DME Name: Aldehyde oxidase (AOX) PDB ID: Not Available MYEFILNGRNVSVSEDMNLLEYLRDHEDLTSVKNGCAEGACGACMILLDGKAVRACINTT AKVHGKDIKTVEGLTEFEKKVFTWAFSKAGAVQCGFCIPGMIISAKALLDKNLNPNKKEI KTAIRGNVCRCTGYVKIIKAIEMAAEAFRDGKLILNEEYKGKIGENIPRIDARDKILGIG KYVDDMKVEGMIYGSALRIKYPRALVKSIDISEALKHPDVETIITAKDIPGNRYIGHIIK DWPAMIDVGEETRYVGDSVALVAAKNKKALKEILNLIKVEYEELEPISNPDMAMDEDAPK IHPKGNVLTVEKVNRGDVDEAIANSKYVVSNHYSTPFTEHAFLELESALAMPDEDGVIIY TGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKEDMSVQHHAALLAWIIKKPVKV TLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIVADTGAYASLGGPVLQRACTHA AGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFASECNLNLLAQKVGISPWEIRFKN AVEPGDALPNGQIADKGTAIKETILAVKDIYENNKYVGIACCMKNSGVGVGLPDIGRCNL VVIKGKVHIRTSAACIGQGLGTILIQIICETTDLLPEQIILDLPDTKFAPNSGTTTASRQ TVFTGEATRIASLKLKDKLLTTSLEECEGEEFYGEYQGITDPINSDKKNPVSHVAYGYAT QVVILNDDGKVEKVVAAHDVGKAINSTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKF GTLGLFRATDIPEIQPIIIEKNTNDLAYGAKGIGEITTIPTAPAAQGAYYKFDGEFRKKL PLKDTAYRRKK > DME ID: DME1094 DME Name: Beta-lactamase (blaB) PDB ID: 1RGY MMKKSICCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAIPGMAVAIIYEGKPYY FTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDRIARGEIKLSDPVTKYWPELTGKQ WRGISLLHLATYTAGGLPLQIPGDVTDKAELLRFYQNWQPQWTPGAKRLYANSSIGLFGA LAVKSSGMSYEEAMTRRVLQPLKLAHTWITVPQSEQKNYAWGYLEGKPVHVSPGQLDAEA YGVKSSVIDMARWVQANMDASHVQEKTLQQGIELAQSRYWRIGDMYQGLGWEMLNWPLKA DSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTGGFGSYVAFVPEKNLGIVMLA NKSYPNPARVEAAWRILEKLQ > DME ID: DME1095 DME Name: Beta-lactamase (blaB) PDB ID: 1A7T; 1A8T; 1HLK; 1KR3; 1ZNB; 2BMI; 2ZNB; 3ZNB; 4ZNB MKTVFILISMLFPVAVMAQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVI NNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYA NQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGG CMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVN QYIESTSKP > DME ID: DME1096 DME Name: Azoreductase (azoR) PDB ID: 1TIK; 1V4B; 2D5I; 2Z98; 2Z9B; 2Z9C; 2Z9D MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALR PSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFR YTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYG PEMAAKAQSDAKAAIDSIVSA > DME ID: DME1097 DME Name: N-ethylmaleimide reductase (nemA) PDB ID: Not Available MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAEYYRQRASAGLIISEAT QISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQLWHTGRISHASLQPGGQAP VAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGIVNDFRQAIANAREAGFDLVE LHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEVVDAGIEEWGADRIGIRVSPIGT FQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDWAGGEPYTDAFREKVRARFHGPIIG AGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLVARLQRKAELNPQRAESFYGGGAEGYT DYPTL > DME ID: DME1098 DME Name: Oxygen-insensitive NADPH nitroreductase A (nfsA) PDB ID: 1F5V MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREEL VTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAE SLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWPADNPDLKPRLPASILVHENS YQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR > DME ID: DME1099 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MNDDAAWGAPALDLPRYLHRIGLQAPPAPDLAGLSTLVRAHALTLPWENFDAVRGIPGEL TIDALQRRMIEGRRGYGCTGHVPLLAAALQRTGFRFGAASGRVLVDGGPSASTHALLIVE VDGAPHLAEVGFGAVPLAPLRLESGLEQDAGGWRYRLTAEAVGFGEEWRLDFLDPSSGQW RPQYRFALADRTWSDLRMTNFYVATSPHSPFRGRLMAVVNRPGERHVLTRDAVISTRPDG FRETVPYVAADRRAILAESFAIDLPEDEAAALAAVSGS > DME ID: DME1100 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MDTQRYLQHIGFIGAARPDLPTLQQLHHRHMLSVPFENLSIIYHQGIRLAPEALFSKVVE RNRGGFCYELNTLFALLLREIGFKVSFISGEIRARDGHFGPPYDHLALRVDLEDQAWLVD VGFGDSFLTPLKIVVAEPQPQASGTFHLEQEGEYYLLERRNGDQRSHAKTLYRFTIQPRA LHEFDEMCRFHSTSPQSHFTQRLVCSRPTDHGRVTLSDMKLIVTEDHQRHETTLHSEEER RAALWQHFAIDLDR > DME ID: DME1101 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MTPLTPEQTHAYLHHIGIDDPGPPSLANLDRLIDAHLRRVAFENLDVLLDRPIEIDADKV FAKVVEGSRGGYCFELNSLFARLLLALGYELELLVARVRWGLPEDVPLTQQSHLMLRLYL AEGEFLVDVGFGSANPPRALPLPGDEADAGQVHCVRLVDPHAGLYESAVRGRSGWLPLYR FDLRPQLWIDYIPRNWYTSTHPHSVFRQGLKAAITEGDLRLTLADGLFGQRAGNGETLQR QLRDVEELLDILQTRFRLRLDPASEVPALARRLAGLISA > DME ID: DME1102 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MKDISFYLTRLNIKENIKIDNYFLFRFHHAHFYSVPFENFSMKENASSCSLSQIIANKII FNKRGGICFEFAKLLESFFSYTGFVYRTRLARVLIPLMTPATHQLFIISVKGEEWIFDVG FGARGPRAPLRMVDGYVHEHAFLSSKVSRHPAYGWVVSVKENSRLNADWEDIYAFHDTET FLPDISMAYFYTLHSPESLLNTHKVASLPTENGRISIRNNVFTEVNGLSSCSADITDNEE LSQLLSGKFGISIHPQQLQ > DME ID: DME1103 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MTPFLTAYFARIGWSDSASVDIETLKALHLLHNGAIPFENLDVLLPREMQLDDLSLEEKL VTARRGGYCFEQNGVFERALREIGFNVRSLLGRVVLANPSSLPPRTHRLLLVELQGEQWI ADVGFGGQTLTAPIRLQADIEQQTPHGEYRLVQEGDDWILQFRHHDHWQSMYRFDLVVQH QSDYLMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTRYQDGRAVEQINLPDVA SLYALLQEQFGLGVDDVKHGFTEDELATVMAAFDTHPEAGK > DME ID: DME1104 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MDTQRYLQHIGFIGAARPDLPTLQQLHHRHMLSVPFENLSIIYHQGIRLAPEALFSKVVE RNRGGFCYELNTLFALLLREIGFKVSFISGEIRARDGHFGPPYDHLALRVDLEDQAWLVD VGFGDSFLTPLKIVVAEPQPQASGTFHLEQEGEYYLLERRNGDQRSHAKTLYRFTIQPRA LHEFDEMCRFHSTSPQSHFTQRLVCSRPTDHGRVTLSDMKLIVTEDHQRHETTLHSEEER RAALWQHFAIDLDR > DME ID: DME1106 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MSPFLRAYFSRLGWTGEPDVSIDTLRQLHLQHNSAIPFENLDVLLPREIHLDDLALEAKL IAGRRGGYCFEQNGLLERALREIGFNVRSLLGRVVLANPPQMPPRTHRLLLVEVAGERWI ADVGFGGQTLTAPIKLLADIPQQTPHGSYRLVHEGDEWTLQFNHHEHWQSMYHFDLGRQY ASDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKMTLTNFHFTHWENNHVVEKVDFADVS ALYEGLQTRFGLGVDDPKHGFSEAALAAVMAAFDTHPEAGK > DME ID: DME1107 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MTPILNAYFARLNWSGRADVNIETLRALHLQHNCTIPFENLDVLLPREMHLDDRSLEEKL ITARRGGYCFEQNGVFERVLRELGFTVRSLLGRVVLANPPSLPPRTHRLLLVELDGESWI ADVGFGGQTLTAPIRLQADIIQKTPHGEYRLQQEGDDWILQFCHHEHWQSMYRFDRVMQQ QSDHVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENDRAVEQRNLPDVA SLYALLQERFGLGVTDAKHGFTETELARVMAAFDTHPEAGK > DME ID: DME1108 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MHSDSFDLSLYFRRIGYSGPAAADTATLHALMRHQLFAIPFENLDVQAGKIVSMEPDDIA NKLLRQRRGGYCYELNGLFTMALEALGIAWRFVAARPMFYPARRPKTHMAVVAEVEGRQW LCDLGFGSYGIRAPLALDELDTDIIQDFDTFRLSRDAHGDYLLQAKVEGSWANQYGFDLS PQEWIDFAPANFLNSTHPDAVFVQKLLVIQHQPEGRFILLGNTLKSITADRVEKQRLEDD EIAHVLEQRFALSAR > DME ID: DME1109 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MTPILNAYFARLNWSGRAEVNIETLRALHLQHNCTIPFENLDVLLPREMHLDDRSLEEKL ITARRGGYCFEQNGVFERVLRELGFTVRSLLGRVVLANPPSLPPRTHRLLLVELDGESWI ADVGFGGQTLTAPIRLQADIIQKTPHGEYRLQQEGDDWILQFCHHDRWQSMYRFDRVVQQ QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYEGDRVAEQRNLPDVA SLYALLQERFGLGVTDAKHGFTETELARVMAAFDTHPEAGK > DME ID: DME1110 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MTPLTPEQTHAYLHHIGIDDPGPPSLANLDRLIDAHLRRVAFENLDVLLDRPIEIDADKV FAKVVEGSRGGYCFELNSLFARLLLALGYELELLVARVRWGLPEDVPLTQQSHLMLRLYL AEGEFLVDVGFGSANPPRALPLPGDEADAGQVHCVRLVDPHAGLYESAVRGRSGWLPLYR FDLRPQLWIDYIPRNWYTSTHPHSVFRQGLKAAITEGDLRLTLADGLFGQRAGNGETLQR QLRDVEELLDILQTRFRLRLDPASEVPALARRLAGLISA > DME ID: DME1111 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: 1E2T MTSFLHAYFTRLHCQPLGVPTVEALRTLHLAHNCAIPFENLDVLLPREIQLDETALEEKL LYARRGGYCFELNGLFERALRDIGFNVRSLLGRVILSHPASLPPRTHRLLLVDVEDEQWI ADVGFGGQTLTAPLRLQAEIAQQTPHGEYRLMQEGSTWILQFRHHEHWQSMYCFDLGVQQ QSDHVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTRYHQGHAVEQVNVPDVP SLYQLLQQQFGLGVNDVKHGFTEAELAAVMAAFDTHPEAGK > DME ID: DME1112 DME Name: Carboxylic ester hydrolase (CEH) PDB ID: Not Available MNTIIRDTDLGQIKGLELDDNTVQFRGIRYATARRFAYPEPVTSFDGIYDATRFGYACPQ FRTYDPEDQKDPAPFYYKEFREGAEFTYDEDCLFLNIYAPKDAKKVPVIIYIHGGAFLGG CGNENHMDGTAYARKGIIFVSINYRLGVLGFLCDRKLTKESGHSGNYGLYDQLEAIKWVH DHIENFGGDKSNITLFGQSAGAMSIQQHCFSPLTKPYIQKVYMASGAGIGKEFAGVSPVE DSYDYFERLTSLLGDDPEDWRQIPVKELIEKFQSVIDRDLMSHCCPHIDGLIIPKDPAQS LEDKDYADVPYLLSTNSEDMAPQFLHQMSKDFCNTVNRNGGRAYYFYFSRKLPGDDKGAF HSAELWYTIGSIRKCWRPMTQEDFDLSDKLVDMICEFANTGAISYSSFDTPMASFEIHP > DME ID: DME1113 DME Name: Thymidylate synthase (thyA) PDB ID: 1BO7; 1BO8; 1BP0; 1BP6; 1BPJ; 1JMF; 1JMG; 1JMH; 1JMI; 1LCA; 1LCB; 1LCE; 1NJA; 1NJB; 1NJC; 1TDB; 1TDC; 1THY; 1TSL; 1TSM; 1TSV; 1TSW; 1TSX; 1TSY; 1TSZ; 1TVU; 1TVV; 1TVW; 1VZA; 1VZB; 1VZC; 1VZD; 1VZE; 2G86; 2G89; 2G8A; 2G8D; 2TDD; 2TDM; 3BNZ; 3BYX; 3BZ0; 3C06; 3C0A; 3IJZ; 3IK0; 3IK1; 4TMS MLEQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTKKVPFGLIKSE LLWFLHGDTNIRFLLQHRNHIWDEWAFEKWVKSDEYHGPDMTDFGHRSQKDPEFAAVYHE EMAKFDDRVLHDDAFAAKYGDLGLVYGSQWRAWHTSKGDTIDQLGDVIEQIKTHPYSRRL IVSAWNPEDVPTMALPPCHTLYQFYVNDGKLSLQLYQRSADIFLGVPFNIASYALLTHLV AHECGLEVGEFIHTFGDAHLYVNHLDQIKEQLSRTPRPAPTLQLNPDKHDIFDFDMKDIK LLNYDPYPAIKAPVAV > DME ID: DME1115 DME Name: S-adenosylhomocysteine nucleosidase (mtnN) PDB ID: Not Available MKIGIIGAMEEEVTLLRDKIENRQTITIGGSEIYT > DME ID: DME1116 DME Name: D-Lactate dehydrogenase (ldhA) PDB ID: Not Available MRILFFSSQAYDSESFQASNHRHGFELHFQQAHLQADTAVLAQGFEVVCAFVNDDLSRPV LERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEHAVGLILTLNRRL HRAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFARIMTGFGCELLAYDPYPNPR IQALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNA AALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVTAHQAFLT REALAAIADTTLDNIAAWQDGTPRNRVRA > DME ID: DME1118 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MMNKNDQETQQMINNVDLEKTFLGSVEAGQSLPTYTLPDDPMAPDVAAQLVEHYRLNEAK ANQNLATFCTTQMEPQADELMKNALNTNAIDKSEYPKTAAMENYCVSMIAHLWGIPDNEK IYDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDIEDLHSHKPNLVIMSGYQVVWE KFCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGIIGIEGITYTGSVDDIQTLDNLV TEYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKNVVSINVSGHKYGMVYPGLGWI VWRHDTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHISAQYYNFIRFGLSGYKTIMQN VRKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAPVGWTLYDLESELAKYGWQVPA YPLPKNRDDVTISRIVVRPSMTMTIADDFLDDLKLAIDGLNHTFGVTTTVDQDNKTTVRS > DME ID: DME1120 DME Name: Glutamate racemase (MurI) PDB ID: 1B73; 1B74 MKIGIFDSGVGGLTVLKAIRNRYRKVDIVYLGDTARVPYGIRSKDTIIRYSLECAGFLKD KGVDIIVVACNTASAYALERLKKEINVPVFGVIEPGVKEALKKSRNKKIGVIGTPATVKS GAYQRKLEEGGADVFAKACPLFVPLAEEGLLEGEITRKVVEHYLKEFKGKIDTLILGCTH YPLLKKEIKKFLGDVEVVDSSEALSLSLHNFIKDDGSSSLELFFTDLSPNLQFLIKLILG RDYPVKLAEGVFTH > DME ID: DME1121 DME Name: Glutamate racemase (MurI) PDB ID: 2JFN MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLLPDLHYIYAFDNVAFPY GEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPALREKFDFPVVGVVPAIKP AARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEMLGSAEMVELAEAKLHGEDVSL DALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVLPEGTRLVDSGAAIARRTAWLLE HEAPDAKSADANIAFCMAMTPGAEQLLPVLQRYGFETLEKLAVLG > DME ID: DME1123 DME Name: Glutamate racemase (MurI) PDB ID: Not Available MDNRPIGVMDSGLGGLSVVRVIQQKLPNEEVIFVGDQGHFPYGTKDQAEVRQLALSIGAF LLKHDVKMMVVACNTATAAALPALQAALPIPVIGVIEPGARAALAQDKKGPIGVIATTAT TTAGAYPATIERLAPGTPVIAKATQPMVEIVEHGQTGTAKAQEVVSEQLMTFKEHPVKTL IMGCTHFPFLAPEISKAVGPTVALVDPAKETVATAKSWLEQHQAMGNHAHPNYHLYSTGN LPDLRAGVNKWLLSGHFDLGTAQIEEGD > DME ID: DME1124 DME Name: Glutamate racemase (MurI) PDB ID: 1ZUW MLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPRPEEEVLQYTWELTNY LLENHHIKMLVIACNTATAIALDDIQRSVGIPVVGVIQPGARAAIKVTDNQHIGVIGTEN TIKSNAYEEALLALNPDLKVENLACPLLVPFVESGKFLDKTADEIVKTSLYPLKDTSIDS LILGCTHYPILKEAIQRYMGEHVNIISSGDETAREVSTILSYKGLLNQSPIAPDHQFLTT GARDQFAKIADDWFGHEVGHVECISLQEPIKR > DME ID: DME1125 DME Name: Glutamate racemase (MurI) PDB ID: Not Available MKIGFFDSGIGGMTVLYEAIKVLPYEDYIFYADTLNVPYGEKSKGKVKEYIFNAAEFLAS QNIKALVIACNTATSIAIEDLRRNFDFPIIGIEPAVKPAINKCTEERKRVLVVATNLTLK EEKFHNLVKEIDHHDLVDCLALPGLVEFAENFDFSEDKIIKYLKNELSSFDLKQYGTIVL GCTHFPFFKNSFEKLFGIKVDMISGSVGTAKQLKKVLADRNQLGKGSGSITFFNSGHKIV DQEVISKYKRLFEILDETQRSHVGH > DME ID: DME1126 DME Name: Glutamate racemase (MurI) PDB ID: 2DWU MSVCHKHSVIGVLDSGVGGLTVASEIIRQLPKESICYIGDNERCPYGPRSVEEVQSFVFE MVEFLKQFPLKALVVACNTAAAATLAALQEALSIPVIGVIHPGARAAIKVTKKGKIGVIG TVGTIQSNMYEKALHELDTYLKVHSHACPTLATVVENRLEDTAYVTQQVKQALLPLTKED IDTLILGCTHYPLLESYIKKELGEDVTIISSAEETAIELSTILQHKGILADNLNPKHRFF TTGSVSSFEHIAERWLGYQISVDCVDLPVKNARICN > DME ID: DME1128 DME Name: Cellobiose 2-epimerase (CE) PDB ID: Not Available MSSIKQAAEEMLLQTIIPFWKGLRDEENGGFYGYMDFDLKLDKKAEKGCILNSRILWFFS EAAMLTGRADLAEDARHAYQFFLKNCYDEANGGVYWSCDYTGKPQDTTKHTYNQGFAIYA LSAYYRLTKDPVALTYAKKIFHLIEQHCTDSEGYLEAFTIDWKPESNEKLSENGVMAAKT MNTLLHVFEGYAGLYQASHDPEVGKALRRILDIYEHKIYSPELHRQLVFFDQHYNSIIDL YSYGHDIESSWLIDWGCDLLGDAALSKRIHAINSDLAAHIYKEAYIDHSVVNECDRGKVN TTRVWWVQAESVLGFVNEYNKSGDAKYRDAAADIYHYICNVMVDKRPGSEWFWEVDADGK PSSRKPILEPWKCPYHNGRMCMELIRRNPDVTV > DME ID: DME1129 DME Name: Cellobiose 2-epimerase (CE) PDB ID: Not Available MRNEIQKELIDAIIPFWEALRDDEYGGFYGYMDYDLNLDKKAEKGCILNSRITWFFASAY KALKDPKLLDEAAHGYEFLKEYCIDREYGGIYWSMNYDGSPKDTTKHTYNQAFSIYALSA YYEASGDSEALDLALQLFHTIEEKCTDEGGYLEAFTREFKPESNDKLSENGVLAERTMNT LLHALEAYTELYKVSKDSKVKERLKWLLDVFADKVYNPELKRQEVFFDKDYNSLIDLYSY GHDIETSWLLDRATEVLGEAEYTEKITKITDILAEQIYEIAFDGHSVLTECEKGVPYTVR VWWVQAESIVGFINAYQKSGDKKYYEAAEKVWEYIKEYFIDKRPGSEWFWDLNADGTPRV GRPIVEPWKCPYHNGRMCLEIMNRLADGK > DME ID: DME1130 DME Name: Cellobiose 2-epimerase (CE) PDB ID: Not Available MLARECKKELTEHIIPFWNSLEDNDNGGFYGYVGNDLTLDKNAPKGVILHSRILWFYSNC YLVLKDQNCLKKAKHAYEFLSKYCVDKENGGVYWMMNADGTVNDSMKHTYCQAFFIYAMS SYYDASKDKAALELALDVFATVEEKCRDDVAYLEAFSKDWNIIPNDALSENGLMADKTMN TTLHVMEAYTELYRVSGDKRVLKALRFTLEITLDKIYDKNGGKLFVFFDKNLNEIGDIYS YGHDIEATWLIDRACDVIGDEHLSKRCAEMNKVIVKNIADRALSNGRLNNEVEHGVVNTW HIWWVQAEGVVGFCNAYQRYGDARYLEISRTLWNYIKDKMIDKRPGGEWHSQLDDNDQPA DFKPVVDPWKCPYHNGRMCLEIISRM > DME ID: DME1132 DME Name: Cellobiose 2-epimerase (CE) PDB ID: Not Available MGNYKQMKELAKAHLSEVVIPFWNKLKDEENGGFYGYLDYDLQLDKKAVKGCILNSRILW FYSNAYLTLGEEGLLSYAKHAYEFLKNHCYDQTYGGIYWSLNYDGSTYDTTKHTYNQAFA VYALSSYYFATKDEEAINLAKSIIGIMEKKCTDSFGYLEAFDRDFLPIDNELLSENGVIA HKTMNTLLHVFEAYTEYYRVTGDMEIKERLMRMLDIIQIKVYNPNLHRQEVFFDVYMNSI LDLHSYGHDIEAAWLIDRGLDVLKEPKYDYLLKPITKDLTNQIYQTAYQDHSLLNESEKG KVNTSRIWWVQAEAVVGFLNGYENDRNETRYYEAATDIFQFILENVHDKRTGSEWFWEVD KEGKPFNKKPIVEPWKCPYHNGRMCFEILRREI > DME ID: DME1133 DME Name: Cellobiose 2-epimerase (CE) PDB ID: Not Available MKNEVVYKQLTEKILPFWNAMRDDENGGFYGYMSEDLHIDDHADKGCILNSRILWFYSTA YMYLQDEKLLDNAKHAFEFLKTYCFDPMCGGIFWSVRYNGKPADTTKHTYNQAFAIYALS AYYEATGSIEAIAIAEIIYEKIEDTMRDTKGYLEAFTRDFRPADNDKLSENGVMAERTMN TLLHIIEAYSALVHALRKKVADPAKGDVRDELFMNVVENKLAAALELMRDKFYNSDRHRL DVFFDKEYESLIDLTSYGHDIEASWLLEWAAGILDDEEITESLHPISSDLVEKVYKEAFD GHSIVNECEDGDVNTDRIWWVEAESVLGFLKAFEREGKEEYRKAAHEILAFILDKQVDKR EGSEWFEMLKEDGTPCHKPMVREWKCPYHNGRMCLEILKSGIEIG > DME ID: DME1134 DME Name: Cellobiose 2-epimerase (CE) PDB ID: 3VW5 MMISEIRQELTDHIIPFWNKLRDDENGGFYGYLSYGLGLDKKADKGVILHSRILWFYSNA YMTLGGDELLDNAKHAYEFIKNNCIDYEYGGVYWMMDFEGKPADTMKHTYNIAFAIYALS SYYRASGDKEALALAYRPFEDIEKNTLYEYGYREAFDRQWRLVDNEALSENGLKADKTMN AILHLIEAYTELYKADGNEKVADRLKFQLGQMRDIVYTPDTNALKVFFDTAFNLVGDIHS YGHDIEATWLMDRACDVLGDEDLKKQFAEMDLKISHNIQDIALEDGALNNERDKNEIDKT RVWWVQAEAVVGFINAYQHSGDEKFLESAKSVWENIKEYIIDKREGGEWYSEVTFDHTPH DYKETVGPWKCPYHNGRMCMEVITRGVDI > DME ID: DME1136 DME Name: Fructokinase (scrK) PDB ID: Not Available MIIGAVEAGGTKFVDGVGNEKGEIFER > DME ID: DME1137 DME Name: Maltose phosphorylase (malP) PDB ID: Not Available MKRIFEIDPWKVITHKFDPKDKRLQESMTAIGNDYMGMRGNFEEGYSGDSLQGTYLAGVW FPDKTVVGWWKNGYPKYFGKTPNAPSFIGIGINVNGEKVDLAKVKFSDFELSLDMHQGLL SRSFIYEGKDVKVKLEFERFLHIVQKEAALIKVKATVLEGHAKIDFDSTLDGTVVNEDSN YGDRFWIPLGEDKDEKTIQVKTKKNPYDVPQFTVLLKEALRNNGVAVNGEVTTEDAKLSE RFSVELDEGQSYELEKDVIVVTSRDVEEKDQAAVANNLMSKLQTKSFEDNLADHTEAWKK RWETSDVEISGDDAAQQGIRFNICQLFMTYYGEDKRLNVGPKGFTGEKYGGATYWDTEAF IVPMYLAVTKPSVTRALLQYRHDQLPGAYHNAKEQGLPGALFPMVTFNGIECHNEWEITF EEIHRNADIPHAIAMYTDYTGDDSYVKNEGMDVLVGTARFWAARVHWSKMRNKYVMHGVT GPNEYENNVNNNWFTNTMARWLLKYTLERLPLATKEAQERVRVTDEEKAKWQDIVDNMYL PEDEDLGIFLQQDDFLDKDIRPVTEIEDQRPINQHWSWDKILRSPFIKQADVLQGIYFFD DQYTMDQKEKNFDFYEPLTVHESSLSPCIYSIMAAELGKKEKAVELYQRTARLDLDNYNN DTVDGLHITSMSGSWLAIVQGFAGMRYDHDQLKFNPFVPDGWDHYSFKINYRGRLIEVYV DHDECKITLLSGDDLEVMVHDNKLDLKEGKTKCLKA > DME ID: DME1138 DME Name: Alpha-glucosidase (aglA) PDB ID: Not Available MEKKWWKESVVYQIYPKSFKDSNGDGVGDIRGIIQKLDYLKELGVNVLWISPMLESPQDD NGYDISDYRRIYKEYGTMEDYEELLSEAHKRDIRILMDLVVNHTSDEHNWFIESRKSKDN PYRDYYIWKDPVNGKEPNNWGGVFGGSAWEYDAQTQMYYLHLFSKKQPDLNWENEKVRQE VYDMMTFWCEKGIDGFRMDVISMISKDQAFPDGKMNNSLYGDFGPYCVHGPRIHEFLQEM NREVLSRYDIMTVGETSGVTIEEAQKYAGEAGKELNMVFQFEHVDNGSGDYGKWTTEKYD FKEFKRIMIKWQEELQGKAWNSLFLGNHDQPRSVSRFGNDNPAYRETSAKMLATCLHMMQ GTPYVYQGEELGMTNVYFDKLEDYRDIESINFFTELTESGLMTPEYMMKCLMLRSRDNAR TPMQWDDSEQAGFTDGESWIKVNPNYKEINAAQQLKDPNSIFHYYQKLISLRKEKDIIVY GEFEPLYRDDEQIFAYTRKLDQEKLLTVCNFSDKNAEMEIPEEFKGAECLITNLDRTVFE GKIVLKPYEAFVLYKK > DME ID: DME1139 DME Name: Beta-galactosidase (bgaB) PDB ID: Not Available MTVIRNFRRILHGGDYNPDQWLHVPGTVDRDFELMDEAHCNTFSVAIFSWAQLEPEPDRF EFGWLDDIFERCGKSGKKLFLATPSASKPAWLAQRWPDSCRMDRDGTRQRWGVRQNSCFA SPGFRERVRLINRKLAERYADHPALGGWHISNEYHGECACELCRNRFYDYLKQRYGTLEK LNQVYWSAFWGHTFTDWKQVEPFDHSMDAAALDWRRFCSDAVVEFFRMEIDAVREFSDAP VTTNMMGLFPTLDYWKFAPLCDFICDDCYPTWYDGDTEREAAWLSLLHDMHYTMLDKPFV MMESCPGIPNYKPYPKLRRPGEFEREMLLALGHGADGTLYFQWRKGRNNCEKFHGAVVGH DGTDRTMVFRQVAAYGEKLERIAGLADAAKKPEAAVVYDWESNWAFEQCNCAGGKEVKQW DATAISHYRALWNCNIDLAVIDSEQDFSRYKLLVAPMLFMFKPGVLERFRSFVEQGGTLV ATYFSGYVDENNGCFLGGNPGGAAGRELFGVWSEDFDGLQPTTRQSIVWKGKSYPVTDYA ELLHAEGAEVEAVYGDDFYAGTPAVTRKRAGKGNVIYLGARTGMEFLNDFYGALLKESGV EPVLAGLPETVRAARRSAVSGGDYFFLYNLSGKEQPVKLPEAMEDVWNGGGAADTVTLPP NGATVLYRA > DME ID: DME1140 DME Name: Beta-galactosidase (bgaB) PDB ID: 5VYM MSARRNFEWPELLTADGRGIAFGGDYNPDQWSEDIWDDDIRLMKQAGVNTVALAIFSWDR IQPTEDRWDFGWLDRIIDKLGNAGIVVDLASATATAPLWLYESHPEVLPRDKYGHPVNAG SRQSWSPTSPVFKEYALTLCRKLAERYGTNPYVTAWHMGNEYGWNNREDYSDNALEAFRA WCRRKYGTIDALNQAWGTTFWGQEMNGFDEVLIPRFMGADSMVNPGQKLDFERFGNDMLL DFYKAERDAIAEICPDKPFTTNFMVSTDQCCMDYAAWAKEVNFVSNDHYFHEGESHLDEL ACSDALMDSLALGKPWYVMEHSTSAVQWKPLNTRKRKGETVRDSLAHVAMGADAINFFQW RASAFGAEAFHSAMVPHAGEDTKLFRQVCELGASLHTLADAGVQGTELAHSDTAILFSAE SEWATRSQTLPSMKLNHWHDVRDWYRAFLDAGSRADIVPLAYDWSSYKTVVLPTVLILSA ADTQRLADFAAAGGRVVVGYATGLIDEHFHTWLGGYPGAGDGLLRSMLGVRGEEFNILGA EAEGEPGEIRLSSADDSAALDGTTTRLWQNDVNVTGEHAQVLATYAGEEADEWELDGTAA VTRNPYGSGEAYFVGCDLDVADLTKLVRAYLAASSQENADVLHTVRASADATFDFYLPRG KKTVELQGIEGEPVILFQTDREEKPGSYTVRRNGVLVVRR > DME ID: DME1141 DME Name: Aminoglycoside acetyltransferase (aac) PDB ID: 5US1 MGIEYRSLHTSQLTLSEKEALYDLLIEGFEGDFSHDDFAHTLGGMHVMAFDQQKLVGHVA IIQRHMALDNTPISVGYVEAMVVEQSYRRQGIGRQLMLQTNKIIASCYQLGLLSASDDGQ KLYHSVGWQIWKGKLFELKQGSYIRSIEEEGGVMGWKADGEVDFTASLYCDFRGGDQW > DME ID: DME1142 DME Name: Aminoglycoside O-phosphotransferase (aphA6) PDB ID: Not Available GNSVLEPNKIGQSPSDVYSFNRNNETFFLKRSSTLYTETTYSVSREAKMLSWLSDKLKVP ELIMTFQDEQFEFMITKAINAKPISALFLTEQELLAIYKETLNQLNAVAIIDCPFISSID HRLKESKFFIDNQLLDEIDQDDLDAELWGDHKTYISLWNELNETRVEERLVFSHGDITDS NIFIDKSGEIYFLDLGRAGLADEFVDISFVERCLREDVSEETAKIFLKHLKNDRPDKR > DME ID: DME1143 DME Name: Hyaluronidase (hyl) PDB ID: Not Available NESTLLLNTSFEETEAPKSGWDQLGAPKWGVWRPTGSPIVTITKEASRTGEYGLKIAAAQ SARAAVSQDVPVQGGQTYQLGTWLKTDNIVSGQGARLRVVLYEGTQQLGLLYSSRLTGTH DWSQIKMEVKTPANADSIRVQLFFETGTGTALFDDVSLQLIQPATSIAIEESEITIKEQE TGLLHAQMVPADASSKVSWVSADPSIATVDNGKVTGVNPGGTTIMAFTDNGLAATSTVKV IKNDGIERPEVTQLDLQPKELELGSGQVRLLQAIIAPATADAEKLVWSSSNEAVASIQKG LIEAKASGTAVITVETEDGSLKSESQITVTDAVVDEYDQLRKKWKSLMTGLDSYDPTNVR MNEMIQNQTKSAETLWKTMFKNNDRSFLWINFASTDNSADIRDSYRNLTTMAKAFANEHS SLYRNPQLLKDITEALEWLYQNRYNESIAQYSNWWHWEIGVPNELNSLMVLLYDYLDQDS IHRYLKVVDHFQPDPTKSGATTPEKYREALGANRIDVSKVVGVRGVIVKDATKIAAARDA LSQTFENVTEGDGFYEDGSFVQHENIAYNGSYGIVLIEGLTDMLELLSNSTWQVTDPKVT NVYDWIETAYEPFMYKGALMDMVRGRAISRNFLQDHQAGHTIIKSVIRMAQFAPEPYAEK YNSMAKYWLQEDTYLDYFKNAGNFRDITLAKQLLEKQEVTPRGDLDFHKTFASMDRVVHR KSGYAFGISMYSNRIQNYEDMNDENRKGWYTGEGMTYLYNGDLAQYSDDFWPTVDPYRMP GTTVDTMRRADGSGEHRSSESWTGGSTLKNFGSAGMSYDAWNSSLIAKKSWFMFDNEIVA LGAGITSSEDRNVESIVENRKIRNDGSNQLVINGETLNLSNGGQNQTMAAKWAFLEGNVP GADIGYYFPEGKMLTIKKEERTGAWKDINYGGPAEAIKRSYTTMWFDHGVRPEQDTYSYV LLPGLNKEQTHQYSQNPDITILRNDSAVQAVQDVKENIIGANFWKDEKQSAGPLTVYQKA SVTMQEKDGVLEIAVCDPTMENKGSIEIEIDGKAFKVLEADESITVENTKPSIKLKVNVN EAKGKTFTAKLKMIPSQKGNSPNSIR > DME ID: DME1145 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFSIESAKFHHQIGPEKTS TFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKAVTFYREVFQDIIAQGIKL IVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFGDLVNTWITFNEPIVPVECGY LGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHPDHKISIVLNMTPAYPRSDAPED VKAARIAELFQTKSFLDPSVLGVYPAELVSILEEADLLPQYSADELEIIKNNTVDFLGVN YYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGKKVNPHRGWEIYEPGLYDIALNLKEHY GNIEWLVTENGMGVEGEEAFLADGQIQDDYRITFIEDHLIQLHKALGEGANCKGYLLWTF IDCWSWLNAYKNRYGLVALDLESQKRTIKKSGYWFKALSESNGFDK > DME ID: DME1146 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MAVILPAMLASCSAPGFSASAHHEAVRRSNAMSGTLDREKTPAANTDASSHDKAVKAVEA MSMQERVGQLVMAPLYAGSDPSTLQHLIADQHVGSVLVIGNCTSGTAGVAAATAALQSYA PANDQLLMATDQEGGQVQHLQGSGFDRMPSAVDQGRMTTDTLRESAAVWGSQLKSAGINV DLAPVVGTVTVDRASNDPVGALNRDFGLDAAGNAEHAKAFIEGMADSGVGSAIKHYPGLG SVTGNTDFTAEGTLDTTTTLDGAEIGAFNEALRANPSMVMMALATYQAIDPNNPAVFSST LITDYLRGTIGFQGVITSDSMSAAALSGIEPADLGVRLVEAGGDLACIGSSDYVQPVLDG LNAKAAADASFAQKVTQSAIRVMTLKYDMGLAR > DME ID: DME1147 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MFRDDFVWGVASSAYQVEGTDPEDGRGKCVWDVFTEEGHIHENQNAYTACDHMHRYKEDY ALMRQLGIKAYRFSMNWARILPEGTGRVNEKAIAMYRDMIVTMKENGITPYITMFHWELP QALQVKGGWLNPQIVDWFGEYARVIAENFADLCDYFITINEPQCVVGLGHLSAVHAPGVR HTVTDTFQIAHNLLKAHGQAVINLRKYAGRPIKVGYAPTGGVAYPYTDSPEDIEAARKVY FGFYNPLDNWTWNVAWFSDPVFLGHYPEEGLKKFKKYLPDITKEDMELIHQPLDFMGQNI YNGYFVRAGKDGEPEFVDRAPGFPRTAAGWPVTPRAFYYGIKFLYERYKLPLYITENGMS CHDLVSSDHKVHDPNRITFLESYIKGMEKAIDEGADVRGYFEWTFLDNFEWADGYTQRFG MVYVDFTTQERIPKDSAYWYSKVIESNGRCLPETGILWC > DME ID: DME1149 DME Name: CDP-alcohol phosphatidyltransferase (pgsA) PDB ID: Not Available MKKEQIPNLLTIGRILFIPIFIFILTVGNSIESHIVAAIIFAIASITDYLDGYLARKWNV VSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRELAVTGLRLLLVETGGTVL AAAMPGKIKTFSQMFAIIFLLLHWTLIGQVLLYVALFFTIYSGYDYFKGSAYVFKGTFGS K > DME ID: DME1150 DME Name: CDP-alcohol phosphatidyltransferase (pgsA) PDB ID: Not Available MKKEQIPNVLTIGRILFIPLFILILTLGHSQGSHLLAAIIFAVASVTDYLDGYLARKWNV VSNFGKFADPMADKLLVMSAFIMLIELGMAPAWVVAIIICRELAVTGLRLLLVETGGTVL AAAMPGKIKTFSQMFAIIFLLLHWNLIGQLLLYIALFFTIYSGYDYFKGSAHVFKGTFGS K > DME ID: DME1153 DME Name: Histidine decarboxylase (hdcA) PDB ID: Not Available MSELDTKLHKLGVDRIAISPYKQWSRGYMEPGNIGNGYVTGLKVDAGVRDKTDDEVLDGI VSYDRAETKNAYIGQINMTTASSFTGPQGHCIGYDLLRNPEVDTAEPLFTVKQWDGSELP IYDAKPLQDSLVEYFGTNNNRRHYPAPGSFIVCANKGVTAERPMNDSDMKPGQGYGVWSA IALSFAKDPAKDSSMFIEDAGVWETPNEDELIEYLKGRRKAIAKSIAECGQDANTSFKGS WIGFAHAMMEPGQIGNAITVAPYISMPVDSIPGGSILTPDTDMDIMENLTMPEWLDKMEY KSLTANGAIKY > DME ID: DME1154 DME Name: ATP-dependent 6-phosphofructokinase (pfkA) PDB ID: 1ZXX MKRIGILTSGGDAPGMNAAVRAVTRVAIANGLEVFGIRYGFAGLVAGDIFPLESEDVAHL INVSGTFLYSARYPEFAEEEGQLAGIEQLKKHGIDAVVVIGGDGSYHGALQLTRHGFNSI GLPGTIDNDIPYTDATIGYDTACMTAMDAIDKIRDTASSHHRVFIVNVMGRNCGDIAMRV GVACGADAIVIPERPYDVEEIANRLKQAQESGKDHGLVVVAEGVMTADQFMAELKKYGDF DVRANVLGHMQRGGTPTVSDRVLASKLGSEAVHLLLEGKGGLAVGIENGKVTSHDILDLF DESHRGDYDLLKLNADLSR > DME ID: DME1155 DME Name: Beta-galactosidase (bgaB) PDB ID: Not Available MNKWEDFNILSENTMEPRNHFFRYENLEKAKTFNRYYSENFLLLNGIWKFKYFKNPHEVL EEYHSQITADREIQVPNMWQFEGYGQPHYTDEGFPFPIDFPYVSTDNPTGLYQRYFYLSK EFKNKDIILKAEGIESYYELYINGHYVGLNKGSRLITEFDITDFVNISKENLISIKVLQW SDSTYLEDQDMWWISGIFRDIYIYSKNRFCIEKYVVKTEMKNDYKDSDLIIDLELNTEKF LGKNLEIEFTLYNEKEKIFSEKIVPKKKNIKLKKSIKKIIEWNPENPYLYDLFIILRKDK KIIEVIPQKVGFRYIEVKKGLMYLNGKYFMMHGVNRHDNDHISGRTVGFERMEKDIILMK QNNINSVRTAHYPNSPRFYELCDKYGLMVLSEMDIETHGFVNTDDFNMLINNEKYKKMFV SRVVRQVISQINHPSIIIWSLGNESGYGVNVTHMTNEIKKVDTTRLIHYEEDRYAEDVDI ISTMYSRVQMMDNFGRFPSDKPRIICEYAHAMGNGPGGLKEYQEVFYKYPSIQGHFVWEW CDHGIYDKERDIYKYGGDYEDYPNNLNFCMDGLIFSNQKEGPGLKEYKQVISPVLIKKIS DIEYKVINRYWFSNLKDIKIYYEIFNGKKLTECNELENIENGSIIKFPRKIVNASIINFK VYKKNKTDYSAENHLLSVYQFQLEEKKQTYEKDNKIPEFHKITENNNEIVITGKNFSIKF SKLNGKLISYNYSGLELIKKPGSINLYKPVIDNHKKENLKWWLPFYFSVIQEHFRKMKIV KEKNKVKISVNSILAPPVYDFGLNCEYEYEIYGNGQINIKLKGKKYGKFLGIIPKIGFEI GLNKDLQNVKYYGRGENENYTDSKEASIIGFYKTTVDNMFINYPYPQDNGNHQDTKELYL TNHFGQGMSVKSENGLNFSAWNYTKENIDKAKHPDELIKSDFITLNLDYKILGLGSNSWG SEVLETYRVYLEDFEYGFSINTYND > DME ID: DME1156 DME Name: Ribosomal 23S RNA methyltransferase Erm (erm) PDB ID: Not Available MSTYGYGRHEHGQNFLTDHKIINSIVDLVKQTSGPIIEIGPGSGALTHPISRLGRAITAV EVDAKLAAKLTKKTASASVEVVHDDFLNFPLPATPCVIVGNIPFHLTTAILRKLLHAPAW TDAVLLMQWEVARRRAGVGASTMMTAQWSPWFTFHLGSRVPRFAFRPQPNVDGGILVIRR VGDPKIPIEQRKAFQAMVHTVFTARGRGIGEILRRAGLFSSRSETQSWLRSRGIDPATLP PRLRTSDWIDLFQVTGSSPSHHRPISQSGSSQRPPQRKKRGRRR > DME ID: DME1161 DME Name: N-acetylneuraminate lyase (nanA) PDB ID: 5ZJM; 5ZKA MKGIYSALMVPYNEDGSINEKGLREIIRYNIDKMKVDGLYVGGSTGENFMISTEEKKRVF EIAIDEAKDSVNLIAQVGSINLNEAVELGKYVTKLGYKCLSAVTPFYYKFDFSEIKDYYE TIVRETGNYMIIYSIPFLTGVNMSLSQFGELFENEKIIGVKFTAGDFYLLERVRKAFPDK LIFAGFDEMLLPATVLGVDGAIGSTYNINGIRAKQIFELAKNSKIDEALKIQHTTNDLIE GILSNGLYQTIKEILKLEGVDAGYCRKPMKKISQKQIEFAKELHKKFLKN > DME ID: DME1162 DME Name: Beta-fructofuranosidase (BFRU) PDB ID: Not Available MTDFTPETPVLTPIRDHAAELAKAEAGVAEMAAKRNNRWYPKYHIASNGGWINDPNGLCF YKGLWHVFYQLHPYGTQWGPMHWGHVSSTDMLSWKREPIMFAPSLEQEKDGVFSGSAVID DNGDLRFYYTGHRWANGHDNTGGDWQVQMTALPDNDELTSATKQGMIIDCPTDKVDHHYR DPKVWKTGDTWYMTFGVSSADKRGQMWLFSSKDMVRWEYERVLFQHPDPDVFMLECPDFF PIKDKDGNEKWVIGFSAMGSKPSGFMNRNVSNAGYMIGTWEPGGEFKPETEFRLWDCGHN YYAPQSFNVEGRQIVYGWMSPFVQPIPMEDDGWCGQLTLPREITLGDDGDVVTAPVAEME GLREDTLDHGSITLDMDGEQIIADDAEAVEIEMTIDLAASTAERAGLKIHATEDGAYTYV AYDDQIGRVVVDRQAMANGDRGYRAAPLTDAELASGKLDLRVFVDRGSVEVYVNGGHQVL SSYSYASEGPRAIKLVAESGSLKVDSLKLHHMKSIGLE > DME ID: DME1164 DME Name: Xylose isomerase (xylA) PDB ID: Not Available MGLWDIDKIPYVGREKGPQEGLAFHYYDADKVVAGKKMKDWLRFGVAWWHTFDQQLVDPF GTGTAQRPWYGKYSDPEDEALAKVDYAFEFFQKLGVEYFCFHDRDIAPEGDTLRETDKNL DKVVDKIEENMKSTGIKLLWNTSSLFTNPRFVSGASTSPFADIYAYAGGQLKHSLEIAKR LGAENYVFWGGREGYENLWNTQMKREQEHMAKFFHMCHDYAKEIGLDAQFLIEPKAKEPT MFQYDFDAATAINFLRTYDLMDVFKLNLEGNHANLAGHTYQHEIRTAREAGVLGSLDANQ GDKLIGWDMDEFPTDLYETSTVMWEVLAEGQIGPHGGLNFDAKPRRTSFTAEDLFRSHIA GMDSFAAGLLVAAKMHEDKVIENLQAERYSSFDSGIGATVENGTASLASLEEYALDIPQS KLIEATKSDHLESVKATINNYMIDALAEA > DME ID: DME1165 DME Name: Phloroglucinol reductase (PHGR) PDB ID: Not Available MVNVKKEFVDNMFSVKGKVALVTGATGALGCVLSKAYGYAGAKVFMTGRNEKKLQALEAE FKAEGIDCAYGVADPADEAQVDAMITACVAQYGEVNILAVTHGFNKPQNILEQSVADWQY IMDADCKSVYVVCKYVAQQMVDQGKGGKIVVVTSQRSKRGMAGYTGYCTSKGGADLMVSS MACDLSAKYGINVNSICPTVFRSDLTEWMFDPESAVYQNFLKREPIGRLAEPEDFVGYAL FLSSDASNYITGANCDCSGGYLTC > DME ID: DME1166 DME Name: Amylosucrase (AMS) PDB ID: 3UCQ; 3UER MLKDVLTSELAAQVRDAFDDDRDAETFLLRLERYGEDLWESLRAVYGDQVRALPGRLLEV MLHAYHARPAELRRLDEARLLRPDWLQRPEMVGYVAYTDRFAGTLKGVEERLDYLEGLGV KYLHLMPLLRPREGENDGGYAVQDYRAVRPDLGTMDDLSALARALRGRGISLVLDLVLNH VAREHAWAQKARAGDPKYRAYFHLFPDRRGPDAFEATLPEIFPDFAPGNFSWDEEIGEGE GGWVWTTFNSYQWDLNWANPDVFLEFVDIILYLANRGVEVFRLDAIAFIWKRLGTDCQNQ PEVHHLTRALRAAARIVAPAVAFKAEAIVAPADLIHYLGTRAHHGKVSDMAYHNSLMVQL WSSLASRNTRLFEEALRAFPPKPTSTTWGLYVRCHDDIGWAISDEDAARAGLNGAAHRHF LSDFYSGQFPGSFARGLVFQYNPVNGDRRISGSAASLAGLEAALETGDPGRIEDAVRRLL LLHTVILGFGGVPLLYMGDELALLNDYAFEDVPEHAPDNRWVHRPQMDWALAERVRQEPS SPAGRVNTGLRHLLRVRRDTPQLHASIESQVLPSPDSRALLLRRDHPLGGMVQVYNFSEE TVMLPSHVLRDVLGDHVQDRLSGSAFRLDRPTVRLEGYRALWLTAGEAPA > DME ID: DME1167 DME Name: Dextransucrase 1 (dsrF1) PDB ID: Not Available MFSVLLVAGSVSYFPKSAKAYTSGTSLDNRVIFQSFSLYMPYESNMYKILSAKGNELKDW GITDIWLPPAYRSFNAARYMEGYAIADRYDLGEFNQGPNNTRPTKYGTSDELKSMVSVLH ANGLKVQEDLVPNQVLGLSKREAVYVTRVDQDGNLFKNPYTTGLTTQIRANLYLAYTKGG GEGQAKYGYIKEWNKKYFNGTSLQGQGMDRVMKDSEGIPYRYFGPNKPNYLPSWLDEAAA ANKINTVDTYLPVDGWYAAKDAKTSDNYWKPMLMHDPGYLKYMKSHGYSSVDDILNGDNG QIASLTDAYIASQPGYGFGSEERSFKNDDSGSDDQDQFLFVKKNGTTVPNLYNTISGHNQ FLVGMDIDNGNPTVQKEQIHWMNWLLDTYQFDGFRIDAAGHYDKQVLLDEGDVMKQHFGS HLNDHLSYIESYQSAGTDFENENGNPQLMMDYALFYSLQNALGKNSPSNSLSTIATNAVV NRASAGTANATPNWSFVNNHDQEKNRVNKIMLDQYGIKPGIHYDTSAPKAFQDLYDKKTE AKALDIYEKDMESTVKTYAPSNVPSQYAYILTNKDTVPTVFYGDLYKTNASYMSEHTPYY DTIVKLLKVRKNYAYGDQQVTYYKSNTSGTAGKDLISSVRYGKDQNTGVATIIGNNPKTD TTIKVDMGTRHANQLFEDATGFHNEKLYTDSKGVLTVHVKGTQNAQVKGYLGVWIPSKKA ATPKQGPALQYGKYVTVTNKHYAVYQDFNWKKKNVTAVNKTYLAKVQYHHSNGSTYLSLY DGKGKWAGYINAKAVKTGSGKQGAAIQYGKHVKVTSKNYAVYQNFNWQKKNIRAVNKTYL AKYIYYHINGLSYLSLYDNKGKWIGYINAKAVKSK > DME ID: DME1168 DME Name: Dextransucrase 2 (dsrF2) PDB ID: Not Available MRASPSQFFAISLLSIAISGLLSGAAVAAPAPAALEQVPDGKGGVKWQEVQADKPAEEEQ EGKGRKKFLGIQAITTEPDGSVKVEMGKPEVRQPASGDVFVSNEKLDEHVIFQAFALYQP NDNATYKALAENAPQLAQWGITDVWSPPPYRAASDSKYGEGYAIADRYDLGAYDKGPTKY GTADELKAAIGALHNNDIRIQVDVVPNQIIGLNERHVLPVTGVDMYGKPMNPFLDHYLYS TYSKGSAPGQAEHGVIKEWDYFHFHGTTTQYQGLFRVLSDANSKLYRYLGPNHPENYLPA FLAESDAAKYGKINTIDGYLLADTWFAVENAESENAVYAPLFLYYEEPRSGVVEQTFMDF ARENGYTGSDEDIRATMLAELRMTPNPLGPLMDEYLAAQPGYSKKSEDDAKVTALRYDGP ENDASHIGTNVLDFEFLVGNDLDTIREDVQQEQLNWQKYLLDFGFDGFRIDAASHINTDM LRDEVTQRLNYFAGEDVNEHLSYIESYVAQQVDFEQSNNYGQMAMDAGPFSGLMFSFGRD WAPLRYAFEASLIDRVNGGPALPNWSFVNNHDQEHNILVTVPLTEEEAGGYEPNSQPYEL RQLEKYDADRNSVEKQWAPHNVPAMYAILLTTRDTVPTVFYGDMFMSSKPYMSTPTPYRD DIVNILKLRKQFAKGEQVIRYENSNTGSNGEDLVSNIRLGNDRKTGVAVVAGNNPALDTT ITVDMGAQHRNQWFVDAMGYQPERLKTDKDGRLTVQVKGTQNVDVKGYLAAWVPDLQAQE > DME ID: DME1169 DME Name: Dextransucrase 3 (dsrF3) PDB ID: Not Available MRASPSQFFAISLLSITISGLLSGAAVAAQTPTALEQVPDGKGGVKWQEVQHDASAEEEQ KGQGRKKFLGIQAITTEPDGSVKVEMGKPEVRQPASGDVFVSNEKLDEHVIFQAFALYQP NDNATYKALAENAPQLAQWGITDVWSPPPYRAASDSKYGEGYAIADRYDLGTYGKGPTKY GTADELKAAIGALHNNDIRIQVDVVPNQIIGLNERHVLPVTGVDMYGQPMNPFLDHYLYS TYSKGSAPGQTEHGVIKEWDYFHFHGTTTQYQGLFRVLSDANSKLYRYLGPNHPENYLPA FLAESDAAKYGKINTIDGYLLADTWFAVENAESENAVYAPLFLYYEEPRSGVVEQTFMDF ARSKGYTGSDEEIRETMLAELRMTPNPIGPLMDEYLAAQPGYSKKSEDDAKVTALRYDGP ENDASHIGTNVLDFEFLVGNDLDTIREDVQQEQLNWQKYLLDFGFDGFRIDAASHINTDM LRDEVTQRLNYFAGEDVNEHLSYIESYVAQQVDFEQSNNYGQMAMDAGPFSGLMFSFGRD WAPLRYAFEASLIDRVNGGPALPNWSFVNNHDQEHNILVNVPLTEEEAGGYEPNSQPYEL RQLEKYDADRNSVEKQWAPHNVPAMYAILLTTKDTVPTVFYGDMFVSSKPYMSTPTPYRD DIVNILKLRKQFAKGEQVIRYENSNTGSNGEDLVSNIRLGNDRKTGVAVVAGNNPALDTT ITVDMGAQHRNQWFVDAMGYQPERLKTDKDGRLTVQVKGTQNVDVKGYLAAWVPDLQAQE > DME ID: DME1170 DME Name: Dextransucrase 4 (dsrF4) PDB ID: Not Available MIRTSKKAIAVAVGLIASATASAGDATAPIFVSNAMLDKHVIYQDFAFYQPYDGTVYKTL ARQAPELRNLGITDVWFAPPYRALNDGRFSEGYAVIDRYDLGEFPQGRGNAIATKYGTGA QLREAIESMHRQRINAIADIVPNQMFFSQREVASVTAVDIFGNPTNPSASNVLYPGYSKG GGLGQKQYGVIKQWQAKYENGTSPQALGIDRIMVDGAGAPYRYYGPGDARNHLPAWLEAT DAARVGALNTIDTYLSVDGSYAAQSAATAIPVYRPYLLYYVDPRRDATVQPYLTYMRAHG FPGNSDDAVRQSIINGNTDAVTKATNDYLALQPGYSASSEAGAAAFRFNKPSNADVNKNV LQYEFLLGSDIDNSNATVQNETLNWQRFLLDKYGFDGFRFDAAGHYNTDILRQSAQLMSG RYGHDMNNHLSVIESYVDPQIAFENSNGNGQLAYDGTLYSTMYNTLEQANPGGPLSDIFA KSIVGQARFGAGRAIPNWSFVTNHDQEHNVIAKIPVPPTQKAGYTPDAAIQLAQMSIYDN DRKQAVKQYAPYNVPSAYAVLLTNKDTVPTVFYGDLYESDKAYVSTKTPYYDAITRLLKI RQKFVAGAQVLTYYKTNTSPSVAGQDLLASVRVGTDRGTGVATVIGNNPATDATIRVDMG LQHANQTFTNMFGQWPERLQTDGRGVLTVHVTGSSTPQVHGYLGVWVPTSEGEGSMMGYA S > DME ID: DME1171 DME Name: D-psicose 3-epimerase (DPEase) PDB ID: 3VNI; 3VNJ; 3VNK; 3VNL; 3VNM MKHGIYYAYWEQEWEADYKYYIEKVAKLGFDILEIAASPLPFYSDIQINELKACAHGNGI TLTVGHGPSAEQNLSSPDPDIRKNAKAFYTDLLKRLYKLDVHLIGGALYSYWPIDYTKTI DKKGDWERSVESVREVAKVAEACGVDFCLEVLNRFENYLINTAQEGVDFVKQVDHNNVKV MLDTFHMNIEEDSIGGAIRTAGSYLGHLHTGECNRKVPGRGRIPWVEIGEALADIGYNGS VVMEPFVRMGGTVGSNIKVWRDISNGADEKMLDREAQAALDFSRYVLECHKHS > DME ID: DME1172 DME Name: Aminoglycoside N-acetyltransferase (aacC2) PDB ID: 4E8O MNIMPISESQLSDWLALRCLLWPDHEDVHLQEMRQLITQAHRLQLLAYTDTQQAIAMLEA SIRYEYVNGTQTSPVAFLEGIFVLPEYRRSGIATGLVQQVEIWAKQFACTEFASDAALDN QISHAMHQALGFHETERVVYFKKNIG > DME ID: DME1175 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MASIQFPKDFVWGTATASYQIEGAYNEDGRGMSIWDTFSRTPGKVVNGDTGDIACDSYHR YEEDIALLKNLGVKAYRFSIAWPRIYPDGDGELNQKGLDYYAKVIDGLLAAGIEPCVTLY HWDLPQALQDKGGWDNRDTIRAFVRYAETAFKAFGGKVKQWITFNETWCVSFLSNYIGAH APGNTDLQLAVNVAHNCMVAHGEAVKAFRALGISGEIGTTHNLYWFEPYTTKPEDVAAAH RNRAYNNEWFMDPTFKGQYPQFMVDWFKGKGVEVPIQPGDMETIAQPIDFIGVNFYSGGF GRYKEGEGLFDCEEVQVGFDKTFMDWNVYAEGLYKVLSWVHEEYGDVPIYITENGACYED ELTQEGRVHDAKRADYFKKHFIQCHRLIESGVPLKGYFAWSLLDNFEWAEGYVKRFGIVY TDYKTLKRYPKDSYRFIQSVIENDGFEA > DME ID: DME1177 DME Name: Inositol dehydrogenase (idh) PDB ID: 4MIE; 4MIN; 4MIO; 4MIY; 4MJL MVVKVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAKVYPDDTS LLQDPDIDAVFVVSFGGAHEATVLKALDTDKFIFTEKPLATTLEGAKRIVDKELTKSKKV IQVGFMRRYDQGIRALKEKLDTGIIGAPLVVRASHINPNVASNYSNEMAITDTLIHEIDE MHWLLDDEYTSIQITYPRQSAEVRNEGLHDPQLATLTTKKGTVIQVLVHVTAQYGYEVKL EVIGETGELQLPNYGLGPILRSNANQQTAVEMSWINRFIQAYNTEVQEFIDEVAKSEPPV GPSAWDGYIAAITAAAANRSQKDQETVLINVAGTPTFYQ > DME ID: DME1178 DME Name: Inositol dehydrogenase (idh) PDB ID: Not Available MVVKVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAKVYPDDTS LLQDPDIDAVFVVSFGGAHEATVLKALDTDKFIFTEKPLATTLEGAKRIVDKELTKSKKV IQVGFMRRYDQGIRALKEKLDTGIIGAPLVVRASHINPNVASNYSNEMAITDTLIHEIDE MHWLLDDEYTSIQITYPRQSAEVRNEGLHDPQLATLTTKKGTVIQVLVHVTAQYGYEVKL EVIGETGELQLPNYGLGPILRSNANQQTAVEMSWINRFIQAYNTEVQEFIDQVAKSEPPV GPSAWDGYIAAITAAAANRSQKDQETVLINVAGTPTFYQNKNAIHA > DME ID: DME1179 DME Name: Linoleate isomerase (lai) PDB ID: Not Available MRYTNGNYEAFVHPRKPENVDQKSAYIIGAGLAGLATAVFLIRDGQMSGDRIHILEELPL SGGSLDGSFIPHDGFVVRGGREMENHFECLWDLFRTIPSLEVDNASVLDEFYRIDRDDPN SSNCRIIHNRGERVDDDGKFTLSPKAQEEIIKLFMTKEELLVGKTIEDCFTDEFFESNFW LYWCSMFAFEKWHSAIEMRRYIMRFIHHIEGLPDFSALKFTKYNQYESLVKPLISYLKDH GVDFKYGAQVENVEVDFSNGKKVAKAIVFADKKIKELTENDLVFVTNGSITESSTQGSPT QAAPKTSELGGSWKLWQNLAKQSEEFGHPDVFCKDIPKETWVVSATVTWENLKIQPYFEK LTHRQLRSGKVVTGGIITVKDSNWLLSFTTHRQPHFKEQNDQETVTWVYGLLSNTPGNYI KKPIEDCTGEEITQELLYHLGMPEEEIEAFVKENTNTIPVYMPFITSYFMLREPGDRPLV VPEQSVNLAFLGNFAETERDTVFTTEYSVRTAMEAVYQLLNVDRGVPEVYASAYDLRTLA SSAYYLSDKQKLEDLELSFIKKQALKVGLKKIKGTYIEELLEDAGLI > DME ID: DME1182 DME Name: Endoglucanase A (EGA) PDB ID: Not Available MKWRIGLLTLIAGLALGSVGGQAASRPKSDWLHAKGNRIVDARGKTVRITGLNWFGYNTG TNTFDGLWTANLDKTVKSVANHGFNTIRVPFSVQLVKAWSQKKYPKANINLSTNAALKGK NSLQIWQRFLADCQKNGIKVIIDMHSAKSDPQGHNAPLWKSGKYTTKDYYAALTWLAKRY KKNDTIIGYDLKNEPHGLVTDASYAKWDGSKASNNWRYIAAQAGKKVLKANPHALIFVEG VQSTPKSWKTGYKKSAQYNYTLWGANLRGVAKYPVKVKKSQLVYSIHDYGPSVAPGSSWL QGNFTYNSLMKNYWRPNWYFIHAKKTAPLYIGEWGGYLTGSNLKWMKAERKLITTHKLNF TFWCLNNNSGDTGGLLNSDWTTWNSKLYKFVKPTLWQSKKGQFYSLDGQVKLGTKGLRKP > DME ID: DME1183 DME Name: Endoglucanase A (EGA) PDB ID: Not Available MKWRIGLLTLIAGLALGSVGGQAASRPKSDWLHAKGNRIVDARGKTVRITGLNWFGYNTG TNTFDGLWTANLDKTVKSVANHGFNTIRVPFSVQLVKAWSQKKYPKANINLSTNAALKGK NSLQIWQRFLADCQKNGIKVIIDMHSAKSDPQGHNAPLWKSGKYTTKDYYAALTWLAKRY KKNDTIIGYDLKNEPHGLVTDASYAKWDGSKASNNWRYIAAQAGKKVLKANPHALIFVEG VQSTPKSWKTGYKKSAQYNYTLWGANLRGVAKYPVKVKKSQLVYSIHDYGPSVAPGSSWL QGNFTYNSLMKNYWRPNWYFIHAKKTAPLYIGEWGGYLTGSNLKWMKAERKLITTHKLNF TFWCLNNNSGDTGGLLNSDWTTWNSKLYKFVKPTLWQSKKGQFYSLDGQVKLGTKGLRKP > DME ID: DME1184 DME Name: VanB ligase (vanB) PDB ID: Not Available MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGITKNGVWKLCKKPCTEWE ADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCGEDGAIQGLFVLSGIPYVG CDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEAGALTYPVFVKPARSGSSFGV TKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAVMGNEDDLIVGEVDQIRLSHGIF RIHQENEPEKGSENAMITVPADIPVEERNRVQETAKKVYRVLGCRGLARVDLFLQEDGGI VLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDSLITLALKR > DME ID: DME1185 DME Name: VanC2 ligase (vanC) PDB ID: Not Available MKKIAVLFGGNSPEYSVSLTSAASVIQAIDPLKYEVMTIGIAPTMDWYWYQGNLANVRND TWLEDHKNCHQLTFSSQGFILGEKRIVPDVLFPVLHGKYGEDGCIQGLLELMNLPYVGCH VAASALCMNKWLLHQLADTMGIASAPTLLLSRYENDPATIDRFIQDHGFPIFIKPNEAGS SKGITKVTDKTALQSALTTAFAYGSTVLIQKAIAGIEIGCGILGNEQLTIGACDAISLVD GFFDFEEKYQLISATITVPAPLPLALESQIKEQAQLLYRNLGLTGLARIDFFVTNQGAIY LNEINTMPGFTGHSRYPAMMAEVGLSYEILVEQLIALAEEDKR > DME ID: DME1186 DME Name: VanG ligase (vanG) PDB ID: Not Available MQNKKIAVIFGGNSTEYEVSLQSASAVFENINTNKFDIIPIGITRSGEWYHYTGEKEKIL NNTWFEDSKNLCPVVVSQNRSVKGFLEIASDKYRIIKVDLVFPVLHGKNGEDGTLQGIFE LAGIPVVGCDTLSSALCMDKDRAHKLVSLAGISVPKSVTFKRFNEEAAMKEIEANLTYPL FIKPVRAGSSFGITKVIEKQELDAAIELAFEHDTEVIVEETINGFEVGCAVLGIDELIVG RVDEIELSSGFFDYTEKYTLKSSKIYMPARIDAEAEKRIQEAAVTIYKALGCSGFSRVDM FYTPSGEIVFNEVNTIPGFTSHSRYPNMMKGIGLSFSQMLDKLIGLYVE > DME ID: DME1189 DME Name: Beta-hydroxysteroid dehydrogenase (hdhB) PDB ID: 5FYD; 5GT9 MNLREKYGEWGLILGATEGVGKAFCEKIAAGGMNVVMVGRREEKLNVLAGEIRETYGVET KVVRADFSQPGAAETVFAATEGLDMGFMSYVACLHSFGKIQDTPWEKHEAMINVNVVTFL KCFHHYMRIFAAQDRGAVINVSSMTGISSSPWNGQYGAGKAFILKMTEAVACECEGTGVD VEVITLGTTLTPSLLSNLPGGPQGEAVMKIALTPEECVDEAFEKLGKELSVIAGQRNKDS VHDWKANHTEDEYIRYMGSFYRD > DME ID: DME1191 DME Name: Ampc beta-lactamase (ampC) PDB ID: 5E2G MRFNATRFAATLLVAACATATAGRAAAVTQDDLRDTVTRQIAPLMKQYAIPGMAIGIVAD GKPYVFDYGVMSKQTGKPVTGDTLFEIGSVSKTLTATLASDAQEGGELSLADPAGKYLPE LQGKPFGVVTLLQLGTHTPGGTPLQVPDSIRDDAGLIRYLDAWRPAYAPGTHRKYSNVAI GMLGWLTAKAMHQDFATLMEQRLFPAIGMTHTYINVPAARMADYAQGYTKDGKPVRMTEG MLWQPAYGVRTTAADLLRFVQANMGMIHTAPRLQRAIERTHTGYFRAGPLTQDLIWEQYP YPVALPTLLAGNAPKMLFDAVPASAIQPPLAPNPATWINKTGSTGGFSTYVAFVPAKRIG IVMLANGNVPIEERVKAAYRILGSLGDAR > DME ID: DME1192 DME Name: AmpC beta-lactamase (ampC) PDB ID: Not Available MRITVTRVVATLLVATAAIATTGRAAELTQAHIRQIVTQQVAPAMKQYAIPGVAIGVIVD GKRYVFDYGVMSKDTGKPVTADTLFEIGSVSKTLTATLAADAQEGGELSLSDPVARYVPA LNGKPAGALTLLELGTHTAGGLPQQVPDAIHDDATLIGYFDAWRPASVPGTQRVYSNVGI GTLGWITAKAMKRDFAELMERRLFPALGMTHTYIDVPDARRADYAQGYTTDGTPIRMKPG GLWQPAYGVRTTATDLLRFVQANMGGIDIAPRLQRAIERTHTGYFRAGPLTQDLIWEQYP YPVALPTLLEGNASKMLSDAVPAVALTPPLAPQRNVWINKTGSTNGFSTYVAFVPAKRIG FVMLANRRVPNEVRVEIAYRILASLGGAR > DME ID: DME1193 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MITCLLAVSVLGGKSQAQDLLSNVYGRDYQLLNGKWGAIVDLYDQGERMQVYKNRKPQDN KQFYEYSFDGGLVLNVPADFNSQMPELKFYEGTVWYGRSFDTPKTDGKRLFLYFGAVSYR SKIYLNGEKIASHEGGFTPFQVEITDKVKQKDNFLVVKVNNTRTTDAIPAMSFDWWNYGG ITRDVMLVSVPQSYIKDHFIQLDKVQSNLIRAKVTLSEAKPGINVQVAIPELGIRQNMTT DANGIAQATIKTKKLQRWSPDAPKLYDVTITSESDRLNEQIGFRNLYVKGEDIYLNDQPI FLRSISFHEEIPQRRGRAFSEADATMLLSEAKELGANMIRLAHYPQNEYTVRLAERMGFL LWEEIPIWQGIDFKNTATREKAGRMIKEMVMRDKNRCSVAFWGIANETATSAPRNEFLKH MKQCCLDIDSTRLITAAFDLVRFNRESRDFEMNDSIINILDMVAINKYMGWYHDWPLAPD QAVWNVAPGKPLFISEFGGEALYGKHGDAEVKSSWSEDYQAQLYKDNLEMFKHIPNLRGT SPWILLDFRSPFRFHPHQGGEWNRKGLVSDQGQRKKAWYIMRDYYNQKKTEQ > DME ID: DME1194 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MITCLLTVSVLGGKSQAQDLLSNVYGRDYRLLNGKWGAIVDLYDQGERMQVYKNRKPQDN KQFYEYSFDGGLVLNVPADFNSQMPELKFYEGTVWYGRSFDTPKTDGKRLFLYFGAVSYR SKIYLNGEKIASHEGGFTPFQVEITDKVKQKDNFLVVKVNNTRTTDAIPAMSFDWWNYGG ITRDVMLVSVPQSYIKDHFIQLDKVQSNLIRAKVTLSEAKPGINVQVAIPELGIRQNMTT DANGIARATIKTKKLQRWSPDAPKLYDVTITSESDRLNEQIGFRNLYVKGEDIYLNDRPI FLRSVSFHEEIPQRRGRAFSEADATMLLSEAKELGANMIRLAHYPQNEYTVRLAERMGFL LWEEIPIWQGIDFKNTATREKAGRMIKEMVMRDKNRCSVAFWGIANETATSTPRNEFLKH MKQCCLDIDSTRLITAAFDLVRFNRESRNFEMNDSIINILDMVAINKYMGWYHDWPLAPD QAVWNVAPGKPLFISEFGGEALYGKHGDAEVKSSWSEDYQAQLYKDNLEMFKHIPNLRGT SPWILFDFRSPFRFHPHQGGEWNRKGLVSDQGQRKKAWYIMRDYYNQKKTEQ > DME ID: DME1195 DME Name: Beta-mannosidase (manB) PDB ID: Not Available MKNSFLIGIIIISFFSCKTPMKNKMPTDPQATHETVALYNRLFNLAEKGIMLGHQDDPLY GHGWYGEQDRSDVKGMIGDYPAIFGFELGHIELDSEYSLDSVYFSQIKKHVKEHHARGGI SSFSWHADNIATGNSTWDCAQDTVVRSILPGGSLHKEYLVWLERLANFFLDLKDENGAYI PVIFRMYHEHTGDWFWWSSQQSTPEEYKQLWIMTCDYLQKTKQVHHLLYAYSSSNVQSEE HYLERYPGDQYVDILGFDHYLKGREQKNVEQYKIDFERNIKIVTKCAEQSGKLPVIGETG EESIWDPTYFTNVVYPIINKYKLGWILFWRNAWEPDKPNHYYLPYPGHSSESDFKQFVDQ PLILTNKDVYQQ > DME ID: DME1196 DME Name: Cytidine deaminase (cdd) PDB ID: Not Available MFQELEKLLKITYSPYSKFPVAAVIKDAKGNIWKGVNVENAAYPSGLCAERNALFSSITY GFIPGKIQEIHILANTKEFIKPCAACLQVMIELMEYDADVYLYSITGAVEKRKLVEFLPL AFRKEFLN > DME ID: DME1198 DME Name: Lactate racemase (Lsa784) PDB ID: Not Available MVAIKLPYDQKIITANIADANFAGKLVSQAATYQNPLSEAETVEQSLDNPIDSPKLEELA KGKKNIVIISSDHTRPVPSHIMTPILLRRIRSVAPDARIRILVATGFHRPSTHEELVNKY GEEIVANEEIVMHISTDDSSVVKIGQLPSGGDCIINKIAVEADLLISEGFIESHFFAGFS GGRKSILPGVASYKTIMANHSGEFINSHYSRTGNLMHNPVHKDMVYAAKTAGLKFILNVV LDEDKHIIGSFAGNLETAHKKGCDFVESLSEVDKIDCDIAISTNGGYPLDQNIYQAVKGM TAAEATNKQGGVIIMVAGARDGHGGDGFYHNIADVKDPKEFLDQAINTPRLETVPDQWTS QILARILVQHHVIFVSDLVDPQLITDMHMELATSLDAALERAYAIEGADAKVTVIPDGLG VIVK > DME ID: DME1199 DME Name: L,D-carboxypeptidase A (ldcA) PDB ID: Not Available MTEPTSRRRFLKTCTAAGAGLLQACGTSATSVPPLPSSHSVVKARTVPLQTPRRQSSDGN LLRVVASSGFAEDTNRVNTALTRLYNAGFTVTNQQAGSRRFQRFAGTDAQRAADFQEVAS GRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGTLFFGFSDVCAVQLALLAKGNM MSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVDVPYIQRTDVETEGTLWGGNLSVL ASLAGTPYMPDIDGGILFLEDVGEQPYRIERMLNTLYLSGILGKQRAIVFGDFRMEKIRD LYDSSYDFSAVAKHISRTAKIPVLTGFPFGHIADKITFPLGAHTRIRMNGNGGYSVAFEG YPTLDASALTLDTLLPPPDLPIFPESGVADISE > DME ID: DME1200 DME Name: L,D-carboxypeptidase A (ldcA) PDB ID: Not Available MSLFHLIAPSGYCIKQHAALRGIHRLTDEGHQVNNVEVIARRCERFAGTETERLEDLNSL ARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLICGHSDFTAIQCGLLAQGN VITFSGPMLVANFGADELNAFTEHHFWLALRNKTFTIEWQGEGPTCQTEGTLWGGNLAML ISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYHAGILPRQKAIILGSFSGSTPND YDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVTLPLGAHAILNNTREGTQLTISGHP VLKM > DME ID: DME1201 DME Name: Alpha-L-rhamnosidase (lrA) PDB ID: Not Available MDTQIIKPIAVGDLHITRFTIEHFPGDALGIPTATPRMNWTYSRTVPDGSQILLKISRRI PGAQAREEYTYLPPEDNVLVPWQFTPLASREEVFATVQLVSAAHKPLSDPSATLHFEAGL MQEYEHVADFVGPSWAEPETDHRHLPLVRTEIAIKAKPKRARLYLSALGLVEAEINGVKI GNDALIPGWTNYEQRVQCWTYDVTDELNEGANAMGFWLGDGWYRGRLGFDGGYVNYYGDR LGVFAQLEIEYEDGGIEHVYSNAWDRQWKASLGPIVCSDLCEGERYDARLEQPGWSEPGF DDSNWKPVSEIFYDPAKIENPDTSPVRAHEINEPVSIARTGDTPDGRGIWLVDFGQNCTQ RIRLRIAGLEAGQSVELHHVEVLEPNGEIATRTLRRGQQHDIYTSNGTDAWWEPRFAMHG FRYAQIEGVVGELTVADIECHVYHSVMDRAGELETSNPLLNRLHANALWSMRSNFVSVPQ DCPQRDERMGWTGDICLFAPTAAYLYDVYGFLKSWLKDVRADQVKWGTVPFYVPFIPLGG WAHPQAISTWGDSAVEVPWVLYMESGDPQILADSYELSRDWIDEVAGYLSADGVWDRRPD YVLGQLGDWLDPTAPPDDPTQAMTEKELVATAFFARSCAQAEQIAQILGKSEDVVRFGDL RKHVTSGFLGRFTNLDGTMTSDTQCAYALAIAFGLLDGEPVRRVKAGNRLAKLVRESGGK VSTGFAGTPFVLPALTMTGHNEEAYGLLLSEECPSWLYQVKMGATTTWERWDSMRPDGSL NPGGMTSFNHYALGSVAEWMHAHIGGLEAIEAGWKRFRVAPVIGGGIDHASTSHVTPYGK ASVAWKTSETGVELDVTVPIGATAVVELPDHEPTELIGGTHHLVVAL > DME ID: DME1204 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MDTTARAAGFDPAIASLPPSFRWGVATSAYQIEGAVAEDGRGPSIWDTYCRVPGMVHEGD NGDVACDHYHRMPEDVELIRSLGVDTYRFSVAWPRVQPGGTGPANPKGLAFYDRLVDELL AKGVDPWVTLYHWDLPQELEDAGGWPVRDTAHRFADYSMLVFDALQDRVRTWTTLNEPWC SAMLGYHVGRQAPGRTHFPDAIKAVHHLLLGHGLATRRMREAAVKPTEFGITLNMGHAAP ATDSELDRDAARRADGLGRRIYLHPVVTGEYPADVVADLAARGAELPVRDGDLELISQPI EVLGINHYTSSKHSGTAEDGSTVDADGLPVDRELRYGRPVTAMDWEIVPEQFTELLLQNA REYPDLPPMVITENGAAFDDVVSPDGSVDDADRVAYLDSHIAAVAKAREGGADVRGYFAW SLMDNFEWSYGYEKRFGIVHVDYETQVRTPKASALWYRDVAKRVRES > DME ID: DME1205 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MTMTFPKGFQFGTATAAYQIEGAVDEDGRTPSIWDVFSHTPGRVLNGDTGDKADDFYHRW QDDLKLVRDLGVNAYRFSIGVPRVIPTPDGKPNEKGLDFYERIVDQLLEYGIDPIVTLYH WDLPQYLNEDPYRGGWLNREIAFRMAEYAGIVAKRLGDRVHTYTTLNEPWCSAHLSYGGT EHAPGLGAGPLAFRAAHHLNLAHGLMCEAVRAEAGAKPDLSVTLNLQVNRGDADAVHRVD LIANRVFLDPMLRGYYPDELFAITKGICDWDFVHDGDLKLINQPIDVLGLNYYSTNLLAM SDRPQFPQSTEASVAPGASDIDWLPTDGPHTQMGWNIDPDALYNTLVRLNDDYDHIPLVV TENGMACPDEVEVGPDGVKMVHDDDRIDYLRRHLEAVHRAIEEGANVIGYFVWSLMDNFE WAFGYDRRFGLTYVDYDTEERIRKDSYNWYRNFIAEHSAR > DME ID: DME1206 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MSVTLKEKLYQMFILGTDGGYYKELLKEGLGGIIFFSKDIQTKTQFKSLIDDIKLISKIP PFLSIDQEGGRVERTENIHNGKKYLSAKFAFEKGEKFLKSQTEEISKELKSYGINLNFAP CIDTNTNPNNPIIGVRAFSSNPDEVIKAEKIVSKTYEENGIIPCVKHFPGHGDANADSHL TLPKIDLSLKDMEETHIKPFKSAIENGIDMVMVAHLFCTCFEKEEVPTSLSKNAIDYLRN NLNFDKVAISDDMVMKGVAKFGDVEACEMGIKAGLNLFIYRFSDEKTSNIIQEIYKKAQK DNLLKEKIENSYNKIMALKSKYNIA > DME ID: DME1207 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MTQQQLYTPKGFPKNFLWGGAIAANQAEGAWQTDGRGPSQADIMLLPEKYSRLGSFGEHV TRADIERALADKSGNYPRRRGIDFFHTYDSDLDLMKEMGFNTFRTSFSWSRIFPNGDEKE PNEKGLKFYDKLIQKMLDLDITPVMTISHYEMPLNLITKYGGWENPEMINFFNRFAQVLL DRYHDKVKYWIVFNQVNDVYGWGEFAGLGILKENQPNEKQAKFQAVHHQFIANAQTVKYG HQIDNDIKIGMMLGLTNVYPASTKPQDVMATYKRWNKDTFFFSDVLARGEYPGYMLRYFE DNNIQLSIDQKELDLIKNNPVDFIAFSYYSSSLISADTPDSLLPNPELEESIWGWSFDPI GFRYGFNVLWDRYHLPLFVAENGLGALDTVEDNKIHDAYRIKYLKAHIKQMKEAIKDGVH IFGYAAWGPIDIVSYSQAEMSKRYGFVYVDLDDKGNGTGKRIRKDSFYWYQKVIESNGDQ I > DME ID: DME1208 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MLYPIITESRQLIDLSGIWKFKLNEGNGLTEELSKAPLKDTIEMAVPSSYNDLVESQEVR DHVGWVWYERNFTIPKTLLNERIVLRFGSATHEAKVYLNGELLVEHKGGFTPFEAEINNL LVSGDNRLTVAVNNIIDETTLPVGLVKEVEVDGKKVIKNSVNFDFFNYAGIHRPVKIYTT PKSYVEDITIVTDFKENNGYVNYEVQAVGKCNIKVTIIDEENNIVAEGEGESGKLTINNV HLWEPMNAYLYKLKVELLDDEEIIDTYFEEFGVRTVEVKDGKFLINNKPFYFKGFGKHED SYVNGRGINEAINIKDFNLMKWIGANSFRTSHYPYSEEIMRLADREGIVVIDETPAVGLH LNFMATGFGGDATKRDTWKEIGTKEAHERILRELVSRDKNHPCVVMWSVANEPDSDSEGA KEYFEPLIKLTKELDPQKRPVTVVTYLMSTPDRCKVGDIVDVLCLNRYYGWYVAGGDLEE AKRMLEDELKGWEERCPNTPIMFTEYGADTVAGLHDTVPVMFTEEYQVEYYKANHEVMDK CKNFVGEQVWNFADFATSQGIIRVQGNKKGIFTRERKPKMIAHSLRERWTNIPEFGYKK > DME ID: DME1210 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MRSIAKLMKDWQFTGPDGVTAAVALPHTWNAVDGQDGGNDYWRGTCIYRTSFAAPAFDPA QQQVWLQFEGVNSSAAVLLNGQQLCTHDGGYSTFRAEITELLQAENQLTVRVDNSVNDRV YPQKADFTFYGGIYRDVSLLVVNKNHIALGHFGDTGVKITPDLKEGSADIQVETLVEGEG TVVVELLDAEGNSVARSEGAKASLHLDAPHLWNGVKDPYLYTCIVRLMQDGKPVDEVTTR VGLRSFSVDAKKGFFLNGKPYPLHGVSRHQDRKGLGNAITREMHDEDMALIRELGANTVR LAHYQHDQYFYDLCDKYGMVVWAEIPYISEHLPKGRENTISQMKELIHQNYNHPSIVCWG VSNEITISTKDKADMLDNHRVLNELCHKMDPTRLTTLACYAMCGPFNSVAHITDLVSWNL YLGWYVPGLFLNDLWMGFFHLVYPNRPLGFSEYGAEGMPNLHSAHPRRGDHTEEYQAKYH EYMLKCFDRHPWLWATHVWNMFDFAADARDQGGEPGMNHKGLVTFDRKTKKDSFYLYKAW WSEENFVHICSKRFTDRTEKEIEVKVYSNQKSVTLYADGKKLAEQTGEHIFKFRVPLHGK VELKAVAGDCIDTACFRSVAAPNPSYKLVKTKSKSANWV > DME ID: DME1211 DME Name: Beta-glucuronidase (uidA) PDB ID: 6ECA METSLLYPVTNDQRTDQKLDGLWQFKFDEAGEGEKSGWETGFHDGVSMPVPASFNDFFTD KASREYTGDFWYSRNFFVPSAAKGKALFLRFDAVTHRATIFVNGKEIRTHEGGFLPFAAD ISEAVKYGAENTVVVKGNNELSREALPAGDTITLRNGKKMVRPFFDFYNYSGLNRSVHLL SLPQERVLDYTTTFALAGNDATVNYTVETNGDAPVTVSLADADGQVVATAQGKQGALQVQ NAHLWQVRNAYLYTLTIQLGDDTQTPLDTYTDRIGIRTIKISGTDILVNDKPIYLKGFGR HEDSPFAGRAFDLNVEKKDFALMKWIGANSFRTSHYPYDEQVYKIADEEGFLLTDEVPAV GFKMAAAAFLGGLNQSFFKGPWLKKLHERHIDQIRDLIKRDKNHPSVLAWSLFNEPDTID ENAVPYFKQIFDESKDLDPQGRPRTFTLSEDDTIETSKVLDFPDFYMLNRYPGWYHFGGY QISDGEAGLRDEMDKWQKAGVKKPVVFTEFGADTEAGLHKLPSVMWTEEYQVEVLKMFSR VFDDYDFIKGEQVWNLADFQTVEGNMRVNGNKKGIFTRDRQPKAAAFFYHDRWNKLPLDY KAK > DME ID: DME1214 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKNTLLKVGLCVSLLGTTQFVSTISSVQASQKVEQIVIKNETGTISISQLNKNVWVHTE LGYFNGEAVPSNGLVLNTSKGLVLVDSSWDNKLTKELIEMVEKKFQKRVTDVIITHAHAD RIGGITALKERGIKAHSTALTAELAKKSGYEEPLGDLQTVTNLKFGNTKVETFYPGKGHT EDNIVVWLPQYQILAGGCLVKSAEAKNLGNVADAYVNEWSTSIENMLKRYRNINLVVPGH GKVGDKGLLLHTLDLLK > DME ID: DME1215 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATFIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1216 DME Name: Beta-lactamase (blaB) PDB ID: Not Available LVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIGVAVIVNNRDTVKVNN KSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTWSPMLKDYSGPVISLT VRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQIAYTEEEMSADHNKAY SNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIAAPLLDKEGVVIAHKT GSGCVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQASQYVAHISAVVYSLLM QTSVKS > DME ID: DME1217 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1218 DME Name: Beta-lactamase (blaB) PDB ID: Not Available LVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIGVAVIVNNRDTVKVNN KSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTWSPMLKDYSGPVISLT VRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQIAYTEEEMSADHNKAY SNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIAAPLLDKEGVVIAHKT GSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQASQYVAHISAVVYSLLM QTSVKS > DME ID: DME1219 DME Name: Beta-lactamase (blaB) PDB ID: Not Available LVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPCEIGVAVIVNNRDTVKVNN KSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTWSPMLKDYSGPVISLT VRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQIAYTEEEMSADHNKAY SNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIAAPLLDKEGVVIAHKT GSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQASQYVAHISAVVYSLLM QTSVKS > DME ID: DME1220 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNKSQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1221 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1222 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKLFSLIALIGSFAFGQIKPIQIDPINNNLFVYQTFNSFNGVEYNANGMYLVTNKGIVL FDVPWQKSQYQELNDMLQEKYNLPVIAVFATHSHDDRAGDLSFYNELNIPTYATSLTNSK LKKEGKATSKFEIELGKTYKFGNEKFVFEYFGEGHTSDNVVVWFPKYKVLNGGCLIKGAD AVNLGYTGEANVVEWPKTVHKLVAKHPTIKQVIPGHDNWKATGHIENTFKLLEKK > DME ID: DME1223 DME Name: Beta-lactamase (blaB) PDB ID: 1AXB; 1BT5; 1BTL; 1CK3; 1ERM; 1ERO; 1ERQ; 1ESU; 1FQG; 1JTD; 1JTG; A/C=24-286; 1JVJ; 1JWP; 1LI0; 1LI9; 1M40; 1NXY; 1NY0; 1NYM; 1NYY; 1PZO; 1PZP; 1S0W; 1TEM; 1XPB; 1XXM; 1YT4; 1ZG4; 1ZG6; 2B5R; 2V1Z; 2V20; 3C7U; 3C7V; 3CMZ; 3DTM; 3JYI; 3TOI; 4DXB; 4DXC; 4GKU; 4IBR; 4IBX; 4ID4; 4MEZ; 4QY5; 4QY6; 4R4R; 4R4S; 4RVA; 4RX2; 4RX3; 4ZJ1; 4ZJ2; 4ZJ3; 5HVI; 5HW1; 5HW5; 5I52; 5I63; 5IQ8; 5KKF; 5KPU; 5NPO; 6APA; 6AYK; 6B2N MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW > DME ID: DME1224 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKYTEWKKEIEKIISQVDGKICINFYDLDKKNGFSINGNEKVLSASMIKLLILAELMKK VSENKFSLSDTITITNFMKTGGDGVLKELNAGHHFTLKELATLMIIVSDNQATNILIDFL GMENINFLGKELGLRETFLERRMMDAEASKNGYDNYTSADDISLLLKLIYQEKLINKETS QLMLDILLRQQQGERLQRYLPPDIKIAHKCGDLDNLENDGGIIWLGNKIYILVVLTSGMS NLQCRQTIGKISKFVYDKMEESLE > DME ID: DME1225 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKGKNKINVIIYVIILLFSLGNLVFAEDSTEEQVKQGNSYYENGKYDLAEKYWKMAADKG NVDALYALGILYEDADKLDLAEAYYKLAADKGDADAQYNLGVLYDDQKKYDLAEAYYKKA AAQGDVDAQYNLGCLYDTQKNFTEAEKYYKLAADQGDKGAQYNLGCLYDTQKKFALAEQF YRLAANQGDIDAQYNIGILYKNQKKFVLAEKYWKMAADQGDLEAQNNLGILYEEQKKYDL AEIYYKKAADGGLKDAQYNLGLFYSDRGKKDLSKKYSELAENNK > DME ID: DME1226 DME Name: Beta-lactamase (blaB) PDB ID: 3BYD MLKSSWRKTALMAAAAVPLLLASGSLWASADAIQQKLADLEKRSGGRLGVALINTADDSQ TLYRGDERFAMCSTGKVMAAAAVLKQSESNPEVVNKRLEIKKSDLVVWSPITEKHLQSGM TLAELSAAALQYSDNTAMNKMISYLGGPEKVTAFAQSIGDVTFRLDRTEPALNSAIPGDK RDTTTPLAMAESLRKLTLGNALGEQQRAQLVTWLKGNTTGGQSIRAGLPASWAVGDKTGA GDYGTTNDIAVIWPENHAPLVLVTYFTQPQQDAKSRKEVLAAAAKIVTEGL > DME ID: DME1227 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKPAQTSLLFALLLGLLPAAYAEDYDDEAYQNLITQCTRNQLDSCVTLGIWTRDYLESPA DAYLPLKKACDGKNMKGCNVLANLYLDPYSGLGMDYSKALELYRKACKGGYDNACRNAKE TEQEMRSQTAEDRAVKRQERLEALQRSCMGENDAACRALQRELQR > DME ID: DME1228 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKVLGRTFFRAAAVVISCWSLAGLAQSSLVKEQDTAALSAQVKSVEQTLGARVGVSVFIP SQGVVWNYHGDQRFPMMSTFKTLACAKMLSDVDAGKLALNDTVKVRSEDLMEYSPVLRPL AGTDITLQAACQATMETSDNTAANLVLEKIGGPAALTAYLQSIGDNVTRLDRNEPTLNEA AKHDPRDTTTPNAINHTLNTLVLGETLSSTSRQQLKTWMQDNKVADGLLRSVLPQGVQIA DRSGAGGFGSRGITALVWSAQQDPMFVSIYLTQTEATFDERNAAIVTIGKSIFDTFLTR > DME ID: DME1229 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1230 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1231 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MTKMNRCAALIAALILPTAHAAQQQDIDAVIQPLMKKYGVPGMAIAVSVDGKQQIYPYGV ASKQTGKPITEQTLFEVGSLSKTFTATLAVYAQQQSKLSFKDPASHYLPDVRGSAFDGVS LLNLATHTSGLPLFVPDDVTNNAQLMAYYRAWQPKHPAGSYRVYSNLGIGMLGMIAAKSL DQPFIQAMEQGMLPALGMSHTYVQVPAAQMANYAQGYSKDDKPVRVNPGPLDAESYGIKS NARDLIRYLDANLQQVKVASVARRWPRRTSVITSAGAFTQDLMWENYPYPVKLSRLIEGN NAGMIMNGTPATAITPPQPELRAGWYNKTGSTGGFSTYAVFIPAKNIAVEMLANKWFPND DRVEAAYHIIQALEKR > DME ID: DME1233 DME Name: Cytochrome P450 105D7 (cyp105) PDB ID: 4UBS MTEPGTSVSAPVAFPQDRTCPYDPPTAYDPLREGRPLSRVSLYDGRSVWVVTGHAAARAL LSDQRLSSDRTLPRFPATTERFEAVRTRRVALLGVDDPEHRTQRRMLVPSFTLKRAAALR PRIQETVDGLLDAMEAQGPPAELVSAFALPLPSMVICALLGVPYADHDFFESQSRRLLRG PGIAEVQDARAQLDDYLYALIDRKRKEPGDGLLDDLIQEQLNRGTVDRAELVSLATLLLI AGHETTANMISLGTFTLLRHPEQLAELRAEPGLMPAAVEELLRFLSIADGLLRVATEDIE VAGTTIRADEGVVFATSVINRDAAGFAEPDALDWHRSARHHVAFGFGIHQCLGQNLARAE MEIALGTLFERLPGLRLAAPADEIPFKPGDTIQGMLELPVTW > DME ID: DME1234 DME Name: Cytochrome P450 124 (cyp124) PDB ID: 2WM4; 2WM5 MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFATLRREAPISFWPTIEL PGFVAGNGHWALTKYDDVFYASRHPDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQR LRSIVSRAFTPKVVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMM GIPKADHQRIFHWTNVILGFGDPDLATDFDEFMQVSADIGAYATALAEDRRVNHHDDLTS SLVEAEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGL APTAVEEIVRWASPVVYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFD LARNPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGI KTLPVTWS > DME ID: DME1235 DME Name: Cytochrome P450 51B1 (cyp51) PDB ID: Not Available MTTAIVPRVSGGEEEHGHLEEFRTDPIGLMQRVRDECGDVGWFQLANKHVVLLSGAKANE FFFRSSDEELDQAEAYPFMTPIFGKGVVFDASPERRKEMLHNSALRGEHMKGHATTIERE VHRMIENWGQEGEIDLLEFFAELTIYTSTSCLIGTKFRNQLDSRFAHFYHELERGTDPLC YVDPYLPIESFRRRDEARKGLVALVQDIMHQRVANPPTDKRDRDMLDVLVSITDEQGNPR FCADEVTGMFISLMFAGHHTSSGTSAWTLIELLRHPDAYAAVIDELDELYADGQPVSFHA LRQIPRLENVLKETLRLHPPLIILMRVAKGEFQVEGYPIHEGELVAASPAISNRIAEDFP DPDEFVPERYQEPRQEDLINRWTWIPFGAGRHRCVGAAFATMQIKAIFSVLLREYEFEMA QPADSYRNDHSKMVVQLARPARVRYRRRKMSDNRGH > DME ID: DME1236 DME Name: Cytochrome P450 BM3 (cypBM3) PDB ID: Not Available DKPVQLGCKFADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFA GDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLIQKWERLNADEHIEVP EDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENK RQFQDDIKVMNDLVDKIIADRKASGEQSDDLLTHYAKRKDPETGEPLDDENIRYQIITFL IAGHETT > DME ID: DME1238 DME Name: Ribosomal 23S RNA methyltransferase Erm (erm) PDB ID: Not Available MSTYGYGRHEHGQNFLTDHKIINSIVDLVKESSGPIIEIGPGSGALTHPLSRLGRPITAV EVDAKLAAKLTKKTASASVEVVHGDFLNFPLPATPCVIVGNIPFHLTTAILRELLHAPAW TDAVLLMQWEVARRRAGVGASTMMTAQWSPWFTFHLGSRVPRSAFRPQPNVDGGILVIRR VGDPKIPIEQRKAFQAMVHTVFTARGRGIGEILRRAGLFSSRSETQSWLRSRGIDPATLP PRLRTSDWIDLFQVTGFSPPRHRPISQSGSSQRPPQRKKRGRRR > DME ID: DME1239 DME Name: Folylpolyglutamate synthetase (fpgS) PDB ID: 1FGS; 1JBV; 1JBW; 2GC5; 2GC6; 2GCA; 2GCB MNYTETVAYIHSFPRLAKTGDHRRILTLLHALGNPQQQGRYIHVTGTNGKGSAANAIAHV LEASGLTVGLYTSPFIMRFNERIMIDHEPIPDAALVNAVAFVRAALERLQQQQADFNVTE FEFITALGYWYFRQRQVDVAVIEVGIGGDTDSTNVITPVVSVLTEVALDHQKLLGHTITA IAKHKAGIIKRGIPVVTGNLVPDAAAVVAAKVATTGSQWLRFDRDFSVPKAKLHGWGQRF TYEDQDGRISDLEVPLVGDYQQRNMAIAIQTAKVYAKQTEWPLTPQNIRQGLAASHWPAR LEKISDTPLIVIDGAHNPDGINGLITALKQLFSQPITVIAGILADKDYAAMADRLTAAFS TVYLVPVPGTPRALPEAGYEALHEGRLKDSWQEALAASLNDVPDQPIVITGSLYLASAVR QTLLGGKS > DME ID: DME1240 DME Name: Hyaluronate lyase (hyaL) PDB ID: Not Available MYELLLKRREYLIGNFKDLPLNKRKQIEEIQEKNIEKLEYLENLNIAEVKLKYNNILELA KAYNQVGNVRYRDEKIKVIILKTLKLLRITYYNLSSVEKVNWWQWEIGIPLLLNDIFILM NEKDFDFEKEENLKTSIYFQKDPRYSGNNPVATHPSKKPFRISTGGNRVDTVKVSLFRSI LLNNEEELKLALNSLPEVWKCREKINRIETDTQRDGFYNDGSFIQHGSLAYNGTYGNVLL QGIGEILYVIGDSKYLKYLGDIYSLKDIILNSYKPFMYKGSFPDMLNGRAITRENSSDKT IGHMLLNSIMLISCGLNDEELKNLVASEILKYEDYSYFDKELSPFMYDLVKKNIHNRKKE EYGKIIKVSNIMNRVFIKDDKKAIAIAGHSENISNYESINGENTKGWYTGDGMIYLYTSD VTYTNYWNNSDTRYMSGTTEVYEDLNGINTSQILNVNMSSAKIVKAIEKDNKMIFFMEFE NHNKSLKMYKSYVYTGKKLICLNTNIDTKEKIYTTIDNRLYKEKPKIVMEDKRILINDLI FNIITDHKFNFDIKESEFGYFVKIWIEHKYNENLYYEIIFEYDDKTSLIEDNKENIIIRN GNEKYLINTKEKEVLRFE > DME ID: DME1241 DME Name: Hyaluronoglucosaminidase (nagH) PDB ID: 2JNK; 2OZN; 2W1Q; 2W1S; 2W1U; 2WDB MNKNIRKIITSTVLAAMTISVLPSNLVVFATDGITENFYEIYPKPQEISYSGGEFQISDE INIVYDDGIDTYTKKRVDEVLEASNLEATVSNEIVPGKTNFLVGINESGGVVDNYFNKNI PHDESFFDEKMDANIVSVKDGVIGVIGEDTDSAFYGVTTLKHVFNQLEEGNKIQSFRADD YAEVAHRGFIEGYYGNPWSNEDRAELMKFGGDYKLNQYVFAPKDDPYHNSKWRDLYPEEK LSEIKKLAQVGNETKNRYVYALHPFMNNPVRFDTEENYQNDLGVIKAKFTQLLENDVRQF AILADDASAPAQGASMYVKLLTDLTRWLEEQQSTYPDLKTDLMFCPSDYYGNGSSAQLKE LNKAEDNVSIVMTGGRIWGEVDENFANNFMNNISTEGHPGRAPFFWINWPCSDNSKQHLI MGGNDTFLHPGVDPSKIDGIVLNPMQQAEANKSALFAIADYAWNIWDNKEEADENWNDSF KYMDHGTAEETNSSLALREISKHMINQNMDGRVRPLQESVELAPKLEAFKQKYDSGASIK EDALELIAEFTNLQKAADYYKNNPGNERTRDQIIYWLNCWEDTMDAAIGYLKSAIAIEEG DDEAAWANYSEAQGAFEKSKTYGFHYVDHTEYAEVGVQHIVPFIKSMGQNLSVVIGSIVD PNRIIATYISNRQDAPTGNPDNIFDNNASTELVYKNPNRIDVGTYVGVKYSNPITLNNVE FLMGANSNPNDTMQKAKIQYTVDGREWIDLEEGVEYTMPGAIKVENLDLKVRGVRLIATE ARENTWLGVRDINVNKKEDSNSGVEFNPSLIRSESWQVYEGNEANLLDGDDNTGVWYKTL NGDTSLAGEFIGLDLGKEIKLDGIRFVIGKNGGGSSDKWNKFKLEYSLDNESWTTIKEYD KTGAPAGKDVIEESFETPISAKYIRLTNMENINKWLTFSEFAIISDELENAGNKENVYTN TELDLLSLAKEDVTKLIPTDDISLNHGEYIGVKLNRIKDLSNINLEISNDTGLKLQSSMN GVEWTEITDKNTLEDGRYVRLINTSNEAVNFNLTKFEVNSNEVYEPSLVDAYVGDDGAKK AVDGDLKTRVKFLGAPSTGDTIVYDLGQEILVDNLKYVVLDTEVDHVRDGKIQLSLDGET WTDAITIGDGVENGVDDMFSTPLKNGYKHGNQSGGIVPIDSAYVEGDNLNQKARYVRILF TAPYRHRWTVINELMINNGEYISTVNDPTYISNPIEERGFAPSNLRDGNLTTSYKPNTNN GEISEGSITYRLSEKTDVRKVTIVQSGSSISNAKVMARVGDGSENVTDQWVQLGTLSNSL NEFINRDYNNIYEIKIEWTDVAPNIYEIITLNQEFEFPVNDSLKAKYDELINLSGDEYTL SSFETLKEALNEAKSILDDSNSSQKKIDKALEKLNKAEERLDLRATDFEDFNKVLTLGNS LVEEEYTAESWALFSEVLEAANEANKNKADYTQDQINQIVIDLDASIKALVKETPEVDKT NLGELINQGKSLLDESVEGFNVGEYHKGAKDGLTVEINKAEEVFNKEDATEEEINLAKES LEGAIARFNSLLIEESTGDFNGNGKIDIGDLAMVSKNIGSTTNTSLDLNKDGSIDEYEIS FINHRILN > DME ID: DME1242 DME Name: NADPH-dependent oxidoreductase (nfrA) PDB ID: Not Available MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKEN LREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAEN IAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPF DHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDML EQLQKSGLIQR > DME ID: DME1243 DME Name: NADPH-dependent nitroreductase (nfrA1) PDB ID: 3N2S MNNTIETILNHRSIRSFTDQLLTAEEIDTLVKSAQAASTSSYVQAYSIIGVSDPEKKREL SVLAGNQPYVEKNGHFFVFCADLYRHQQLAEEKGEHISELLENTEMFMVSLIDAALAAQN MSIAAESMGLGICYIGGIRNELDKVTEVLQTPDHVLPLFGLAVGHPANLSGKKPRLPKQA VYHENTYNVNTDDFRHTMNTYDKTISDYYRERTNGKREETWSDQILNFMKQKPRTYLNDY VKEKGFNKN > DME ID: DME1244 DME Name: Nitroreductase (NTR) PDB ID: Not Available MKEQHIIEVNKDICIGCGLCENDCPVNNITIKDKKSVIKNQDCIKCGHCSAICPTAAITL TGFDDEPIEIKNETTVDSNELLMAIKSRRTIRKFKNKEVHSEIIQQIIEAGRFTPSAKNS QDVSYIVLDENKSKYEEIAVKFFRRIKPIVSLFMKSAKEVTIDDNFFFKGAPVAIMVLTK DKISGSLAASNMALMAESYGLGVLYSGFFTTVVNNSRKLRKSLNLKHNDYVVTTLVLGYP DVRYRRTAQKERANVRFL > DME ID: DME1245 DME Name: Nitroreductase (NTR) PDB ID: Not Available MKLDRKDIIDIFNFRFATKEFTGEIIPKEDMEMIAETARLSPSSFGLEPWKFLIVENKEL IKEISEVSWGFQRQASTTSHIVIALTKAGSEVKYDSDYIRNLWINTKGVSEEFFEGIKDV LKNFQVGKLEADETNEKLLEWSKRQTYIALGNMMTAAAMREIDSCAIEGFDKEKVEEILA KKGILDKEKYELTYLIAFGYRKEDPNRKKSRLPKSEVIQWVE > DME ID: DME1246 DME Name: Nitroreductase (NTR) PDB ID: Not Available MNKEYLNDTIKLLCERASCRSFLDKKIPDELLNEIISCGLHAATGGNLQPYSIIKITDDK TKERLVNECDMQSLVKNAPVNLLFCIDWRRIQRWCEASDAPFVATKSYRHFWIALQDTII CAQNICTAADSIGLGSVYIGTVESCFMELKSIFNIPEGVFPVVLLSIGYPNQPLIPAPKL GIEAIVHEESYKDLTIDTLVKLQNEKYNSKKFPLSPTNTASMKEVTLDIGGEDYSNKIIT SIEQQGYINMAQRYFGLHYKANWSCIGNKNFIEALKAYGFTWIMGEDFPTGDK > DME ID: DME1247 DME Name: Nitroreductase (NTR) PDB ID: 1KQB; 1KQC; 1KQD; 1NEC; 5J8D; 5J8G MDIISVALKRHSTKAFDASKKLTAEEAEKIKTLLQYSPSSTNSQPWHFIVASTEEGKARV AKSAAGTYVFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEEADGRFNTPEAKAANHKG RTYFADMHRVDLKDDDQWMAKQVYLNVGNFLLGVGAMGLDAVPIEGFDAAILDEEFGLKE KGFTSLVVVPVGHHSVEDFNATLPKSRLPLSTIVTEC > DME ID: DME1249 DME Name: S-(hydroxymethyl)glutathione dehydrogenase (adh) PDB ID: Not Available MKSRAAVAFGPGLPLEIVEIDVAPPKKGEVLVKISHTGVCHTDAYTLSGDDPEGLFPVVL GHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECDFCTSGKTNLCVAVRETQGKGVMPD GTSRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPQANAEQVCLLGCGVTTGIGAVHN TAKVQEGDSVAVFGLGGIGLAVVQGARQAKAGRIFAIDTNPSKFELAKQFGATDCINPND YDKPVQQVLVEMTKWGVDHTFECIGNVNVMRSALESAHRGWGQSVIIGVAGAGKEISTRP FQLVTGRVWKGTAFGGVKGRTQLPGMVEDAMSGKIELAPFVTHTMELDKINEAFDLMHDG KSIRTVIHY > DME ID: DME1291 DME Name: VanA ligase (vanA) PDB ID: Not Available MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGITKSGVWKMCEKPCAEWE NDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFV GCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVAATFTYPVFVKPARSGSSFG VKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALAVGEVDQIRLQYGI FRIHQEVEPEKGSENAVITVPADLSAEERGRIQETAKKIYKALGCRGLARVDMFLQDNGR IVLNEVNTLPGFTSYSRYPRMMAAAGIALPELIDRLIVLALKG > DME ID: DME1292 DME Name: VanB ligase (vanB) PDB ID: Not Available MNKIKVAIIFGGCSEEHDVSVKSAIEIAANINTEKFDPHYIGITKNGVWKLCKKPCTEWE ADSLPAIFSPDRKTHGLLVMKEREYETRRIDVAFPVLHGKCGEDGAIQGLFELSGIPYVG CDIQSSAACMDKSLAYILTKNAGIAVPEFQMIEKGDKPEARTLTYPVFVKPARSGSSFGV TKVNSTEELNAAIEAAGQYDGKILIEQAISGCEVGCAVMGNEDDLIVGEVDQIRLSHGIF RIHQENEPEKGSENAMIIVPADIPVEERNRVQETAKKVYRVLGCRGLARVDLFLQEDGGI VLNEVNTLPGFTSYSRYPRMAAAAGITLPALIDSLITLAIER > DME ID: DME1294 DME Name: Rifampicin monooxygenase (rox) PDB ID: 5KOW; 5KOX; 6C7S MIDVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHSRSRGLHARSIEVMDQRGLLE RFLAHGEQFRVGGFFAGLAAEWPADLDTAHSYVLAIPQVVTERLLTEHATELGAEIRRGC EVAGLDQDADGVTAELADGTRLRARYLVGCDGGRSTVRRLLGVDFPGEPTRVETLLADVR IDVPVETLTAVVAEVRKTQLRFGAVPAGDGFFRLIVPAQGLSADRAAPTLDELKRCLHAT AGTDFGVHSPRWLSRFGDATRLAERYRTGRVLLAGDAAHIHPPTGGQGLNLGIQDAFNLG WKLAAAIGGWAPPDLLDSYHDERHPVAAEVLDNTRAQMTLLSLDPGPRAVRRLMAELVEF PDVNRHLIEKITAIAVRYDLGDGHDLVGRRLRDIPLTEGRLYERMRGGRGLLLDRTGRLS VSGWSDRVDHLADPGAALDVPAALLRPDGHVAWVGEDQDDLLAHLPRWFGAAT > DME ID: DME1295 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKGSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFVATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1296 DME Name: Metallo-beta-lactamase (blaM) PDB ID: Not Available MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH GLPGGLDLLKHTTNVVKAHTNRSVVE > DME ID: DME1297 DME Name: VanC2 ligase (vanC) PDB ID: Not Available MKKIAIIFGGNSPEYTVSLASATSAIEALQSSPYDYDLSLIGIAPDAMDWYLYTGELENI RQDTWLLDTKHKQKIQPLFEGNGFWLSEEQQTLVPDVLFPIMHGKYGEDGSIQGLFELMK LPYVGCGVAGSALCMNKWLLHQAAAAIGVQSAPTILLTNQANQQEQIEAFIQTHGFPVFF KPNEAGSSKGITKVTCVEEIASALKEAFTYCSAVLLQKNIAGVEIGCGILGNDSLTVGAC DAISLVDGFFDFEEKYQLISAKITVPAPLPETIETKVKEQAQLLYRSLGLKGLARIDFFV TERGELYLNEINTMPGFTSHSRYPAMMAAVGLSYQELLQKLLVLAKEEVK > DME ID: DME1298 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKTFAAYVIIACLSSTALAGSITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARAS KEYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWERDLTLRGAIQVSAVPVF QQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSA SKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWWVGWVEKETEVYFFAFNMD IDNESKLPLRKSIPTKIMESEGIIGG > DME ID: DME1299 DME Name: Alpha-glucosidase (aglA) PDB ID: Not Available MDDRKFSVLIAGGGSTYTPGIVLTLLDHIQKFPLRKLKFYDIDGERQQRVADACEILVKE RAPEVEFLATTDPEEAFTDVDFVMAQIRVGKYAMRSLDEKIPLKHGVVGQETTGPGGIAY GLRSIPGVIGLVDYMEKYSPNAWMLNYSNPAAIVAEATRRLRPHSRIINICDMPIGIMDR MAQIVGLKDRNDLVFRYYGLNHFGWWTDVRDKTGKDLMPALKQYVAKNGYWLGDKDKDTE ASWVSTFKKAADVYALDPSTLPNTYLKYYLYPKYVVEHSDPNYTRTDEVEAYREKHVFDE CDRIIAAGTAADTHFKSDDHATYIVDLCTAIAYDTKQRMLAIVPNDGAIENIDPEAMVEV PCLFGANGAERLAMGKAATFQKGLITEQNCVEKLTVDAFEQQSYTKLWEAMSLCKIVPDA SVAKEILDEMVVANKDYWPELK > DME ID: DME1300 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVREL CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW > DME ID: DME1301 DME Name: Catalase-peroxidase (katG) PDB ID: 1UB2; 3WNU; 3WXO; 3X16; 4PAE MTATQGKCPVMHGGATTVNISTAEWWPKALNLDILSQHDRKTNPMGPDFNYQEEVKKLDV AALKQDLQALMTDSQDWWPADWGHYGGLMIRLTWHAAGTYRIADGRGGAGTGNQRFAPLN SWPDNTNLDKARRLLWPIKQKYGNKLSWADLIAYAGTIAYESMGLKTFGFAFGREDIWHP EKDIYWGPEKEWVPPSTNPNSRYTGDRELENPLAAVTMGLIYVNPEGVDGNPDPLKTAHD VRVTFARMAMNDEETVALTAGGHTVGKCHGNGNAALLGPEPEGADVEDQGLGWINKTQSG IGRNAVTSGLEGAWTPHPTQWDNGYFRMLLNYDWELKKSPAGAWQWEPINPREEDLPVDV EDPSIRRNLVMTDADMAMKMDPEYRKISERFYQDPAYFADVFARAWFKLTHRDMGPKARY IGPDVPQEDLIWQDPIPAGNRNYDVQAVKDRIAASGLSISELVSTAWDSARTYRNSDKRG GANGARIRLAPQKDWEGNEPDRLAKVLAVLEGIAAATGASVADVIVLAGNVGVEQAARAA GVEIVLPFAPGRGDATAEQTDTESFAVLEPIHDGYRNWLKQDYAATPEELLLDRTQLLGL TAPEMTVLIGGLRVLGTNHGGTKHGVFTDREGVLTNDFFVNLTDMNYLWKPAGKNLYEIC DRKTNQVKWTATRVDLVFGSNSILRAYSELYAQDDNKEKFVRDFVAAWTKVMNADRFDLD > DME ID: DME1302 DME Name: General stress protein 14 (ywrO) PDB ID: Not Available MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRI VFQFPLYWYSSPPLLKKWQDLVLTYGWAFGSEGNALHGKELMLAVSTGSEAEKYQAGGAN HYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDISHSAKRLAEYIQQPFV > DME ID: DME1303 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MLYSKENKESYLEPVFGSSAEDRDIPKYTLGKEPLEPRIAYRLVKDELLDEGSARQNLAT FCQTYMEDEATKLMSETLEKNAIDKSEYPRTAELENRCVNIIADLWHAPKDQKFMGTSTI GSSEACMLGGMAMKFAWRKRAEKLGLDIYAKKPNLVISSGYQVCWEKFCVYWDIDMRVVP MDKEHMQLNTDQVLDYVDEYTIGVVGILGITYTGRYDDIYALNEKLEEYNSKTDYKVYIH VDAASGGFFTPFVEPDIIWDFRLKNVISINTSGHKYGLVYPGIGWVLWKDESYLPEELIF KVSYLGGEMPTMQINFSRSASHIIGQYYNFLRYGFEGYRTIHQKTSDVAQYLAHAVEQTG YFDIFNDGSHLPIVCYKLKDDANVNWTLYDLADRLQMRGWQVPAYPLPKSLENIIIQRYV CRADLGFNMAEEFIQDFQASIQELNNAHILFHDTQQSGVHGFTH > DME ID: DME1304 DME Name: Glutamate decarboxylase (gadB) PDB ID: 1PMM; 1PMO; 2DGK; 2DGL; 2DGM; 3FZ6; 3FZ7; 3FZ8 MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQIINDELYLDGNARQNL ATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQAVG TNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVELREI PMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDM HIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELV FNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKL GPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPAFTLGGEATDIVV MRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT > DME ID: DME1305 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQIINDELYLDGNARQNL ATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQAVG TNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVELREI PMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDM HIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELV FNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKQ GPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPAFTLGGEATDIVV MRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT > DME ID: DME1306 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MLYGKENRDEAEFLEPIFGSESEQVDLPKYKLAQQSIEPRVAYQLVQDEMLDEGNARLNL ATFCQTYMEPEAVKLMSQTLEKNAIDKSEYPRTTEIENRCVNMIADLWNASEKEKFMGTS TIGSSEACMLGGMAMKFSWRKRAEKLGLDINAKKPNLVISSGYQVCWEKFCIYWDIEMRE VPMDKEHMSINLDKVMDYVDEYTIGVVGIMGITYTGRYDDIKALDNLIEEYNKQTDYKVY IHVDAASGGLYAPFVEPELEWDFRLKNVISINTSGHKYGLVYPGVGWVLWRDKKYLPEEL IFKVSYLGGELPTMAINFSHSASQLIGQYYNFVRYGFDGYKAIHERTHKVAMFLAKEIEK TGMFEIMNDGSQLPIVCYKLKEDSNRGWNLYDLADRLLMKGWQVPAYPLPKNLENEIIQR LVIRADFGMNMAFNYVQDMQEAIEALNKAHILYHEEPENKTYGFTH > DME ID: DME1307 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MSIMHSNINTIAAGYGYSGGADSDSVEVNPLFARPKEAKAFSKFKIPQEGSLPETAYQVV HDDAMLDGNARLNLATFVSTWMDDYANRLYMEAADKNMIDKDEYPKTAEVESRCWHMLAD LWHAPDPMNTIGTSTIGSSEACMLGGLALKRRWKEAREKAGLPADRPNLVMSSAVQVCWE KFCNYFDVEPRYVPISEEHKVLDGYDLDKYVDENTIGVVAIMGVTYTGMYEPVKKISDAL DRIEERTGLDVRIHVDAASGGMIAPFIQPDLQWDFRVKRVYSISTSGHKYGLVYPGLGWV VWRETADLPESLIFKVSYLGGEMPTFALNFSRPGAQVLLQYYMFLRLGFEGYRRVQQAAH DVAKYLSGEIAKMDDFTLWNDGSDIPVFAWMLKDKPDRKWNLYDLQDRLRMKGWLVPAYP MPVDLTQVTVQRIVVRNGFSHDMAESFLKDLKACVKYLDGLKAPMPSEARVSGFHH > DME ID: DME1308 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MIHRSYTLFLIATILLFTSCSVFRGFSLDGFSGPDIYEYQKLERDTIRKGSNVFHFPLVE SHRKIRGDFRLKYKDSGRMRLDSLVEQWFGKDNQLLIIHNDSVVYDQWTEPFYPGKNATV FSVSKSLTALLCGIAIDEGYIKSVDDPVTDYIPELAQYNPTFRSLRIIHLLNMQAGFDFK EHYEFTLKSMSSIAKMAQLQYGHDFTRLFRHVKFKYQPGEKYEYNSLTTALLSWIIERAT GKNYAHYMSEKVWKPLGMEHDAWVTIDSRKHHHAQGFGGIATNVYDLAKIGRLYLNRGKW EGKQIVREEWINRSLETTSENKGYHYCWYYQYYDDKTDNSSFYAFGVGHQFIYINQKKNV IITRIGNNYNWKWWEMSFFDALCNKLF > DME ID: DME1309 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MLKIKRFIFNMVQENCYVLHDETQEGVIIDCGALMPEEEEALRDYIAAEGIQVKHLLHTH SHFDHVFGDQFVYSTYGIKPEMHELEVALYGDVSGQVAMFLHRNISVVVPPLGNVFTGRD EIKFGNHTLEIIETPGHSPGGVCFYCRAEKALFSGDSLFKHEIGRFDFPYGDGAALIDNL KTKILTLPADVNVYPGHGDATSIEEERAYNPYLR > DME ID: DME1310 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MSIFTFFQQLFAQPITQKQIFAEDISKINSLEKAIQQSELVVNYLLQEHYTPSMSICVTK RGFPIWEQGYGYADIENKVGVNPRETLYRIASVSKPLTGMALTKMQEQGWIDWNCSLYDY VPYFPKKQYDFTVKQLAGHLAGIRAYKGKEVFLNRFMSIKEGISVFAEDPLLFEPGTQYY YNSYDINLVSLAMQEARKEPFEWYVTHNVLEPIGMKHTFPDMGGLSPNQSIPYSPDKKKQ FKRSTEVNNFFKLGGGGFLSTAYDVNLMGQAILGKAFLKPEYQEQMLTSQQLNTGKDTGY GIGWQTTTDWQGRTYYGHIGNGIGGYAWFYVYPEEEVVFTFLFNTTNPSIADYMHRIMDC MLKGASYKEYTTHNYPVIHNEQ > DME ID: DME1311 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MMTQSIRRSMLTVMATLPLLFSSATLHAQANSVQQQLEALEKSSGGRLGVALINTADNSQ ILYRADERFAMCSTSKVMAAAAVLKQSESDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTM TLAELGAAALQYSDNTAMNKLIAHLGGPDKVTAFARSLGDETFRLDRTEPTLNTAIPGDP RDTTTPLAMAQTLKNLTLGKALAETQRAQLVTWLKGNTTGSASIRAGLPKSWVVGDKTGS GDYGTTNDIAVIWPENHAPLVLVTYFTQPEQKAESRRDILAAAAKIVTHGF > DME ID: DME1312 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MTYSSKRRTLLLAAATAPLVLTATACASRQAAAPDPATAAAAAAADAMAPAAAAATLADL ERDAGGRLGVCAIDTASGRVIEHRAGERFPFCSTFKAMLSAAVLAQSVERPGLLQQRVKY TKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGPSAVTAYARSIGD DAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRAQLVAWLRGNKVG DKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQTRADARAKDDVI ASVARIVAQTFG > DME ID: DME1313 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MQNGKIVCADAIGVIDKINNQPITTDCTFNVCSISKIYCTVCIMQLVDEGLIQLEDKVAD ILPEFTMKDERYKDITVRMCLDHSSGLPGTQWKHFSVSTTSKFDYYSEVLNYFSNSTLKA DPGTYSTYCNDGFTLAEMVVSKVRNMPYEDVLKKYITEKIGAKSTNTTYTINSDCPLVSE GKKPKEYFPIQGAGGITTSMIDLCKFGQLFLEPNSIISEKSKTLMAKSWGTTFLESDLGA IDFGLGWDLVRHHDPDYDFGDGVLAKGGNSMFFSSRLIIVPKYNAVLAFSETHDCGLEVP TTLMRLFNTYLEPNTYPDYSGIYAHAFGLQKITTIKSSMVVQDKTEKGWIMSDLLNYSNG KWTNEKGNQIFFEGDYLLKTTRNRTGAFAQKAKKQELNSVWKSRLNKKYIVCDTTYYDIV TNQMLCSVEFNRTEDTLSLIVHGNKSEPVISEFPIEVIDDTHAKSYLNTPCNGSRDRIEP YFEDGKLYCASYTYICEDDIEPYNFQLFEKENQVYKINNTLEVLPTICENHRILVLDSNG DLYYDSMDVEEYKPIESGFIILV > DME ID: DME1314 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MTKRFSVLTGSLLLAASLGVQASNTPDQTRLTNTVDKTIHSLMQEYDIPGMAIAVTFRGQ HFFYQYGDASKESNTPVTKETIFELGSVSKTFAGSLISWAQVTGAISFSDKASQHFQPLA GSAFDNINLLNIATYTAGGLPLQFPDEIDNNSKMVDWFQHWQPKYPPGTYRQYSNPSIGL AGYIVAQRLEKPYSILVKNQILSPLGLHHTWFNVPAQEMKNYALGYSKENKPIRINPGVL DEEAYGLKTSAQDLIGFVDANIDPSRVGDSKLAQAIRATHTGYYRTGEMTQGLGWELYHW PVTLEQVLSGNSAEIAYQANKTTELSPPEPPTDALFINKTGSTNGFGAYVAFVPQEQMGI VLLANKNYPNEARIKAAWQILKALK > DME ID: DME1315 DME Name: Azoreductase (azoR) PDB ID: 2HPV MSKLLVVKAHPLTKEESRSVRALETFLASYRETNPSDEIEILDVYAPETNMPEIDEELLS AWGALRAGAAFETLSENQQQKVARFNELTDQFLSADKVVIANPMWNLNVPTRLKAWVDTI NVAGKTFQYTAEGPKPLTSGKKALHIQSNGGFYEGKDFASQYIKAILNFIGVDQVDGLFI EGIDHFPDRAEELLNTAMTKATEYGKTF > DME ID: DME1316 DME Name: Azoreductase (azoR) PDB ID: Not Available MSKVLYIKANIKNEGESRTFKVSDSFVEEYKKNNPEDEIITLDLYKENIDFLRADDLGKL FGPKDEESKNNSILKYAYQFADADKYIIAAPMWNLSFPAILKAYIDYVSVSGITFKYTAE GPVGLLNNKKAVHIVSRGGGYDNSPYEMGDRYLRTILGFFGIKDIETIAIDNLDVMGVNV EEKVEEGIEKAISLAKKF > DME ID: DME1317 DME Name: Alcohol dehydrogenase (ADH) PDB ID: Not Available MNRQFDFLMPSVNFFGPGVIAKIGDRAKMLNMHKPLIVTTEGLSKIDNGPVKQTVASLEK AGVDYAVFTGAEPNPKIRNVQAGKKMYQDENCDSIITVGGGSAHDCGKGIGIVLTNGDDI SKLAGIETLKNPLPPLMAVNTTAGTGSELTRHAVITNEKTHLKFVVVSWRNIPLVSFNDP MLMLDIPKDITAATGCDAFVQAIEPYVSVDHNPITDSQCKEAIQLIQTALPEVVANGHNI EARTKMVEAEMLAGMAFNNANLGYVHAMAHQLGGQYDAPHGVCCALLLTTVEEYNLIACP ERFAELAKVMGFDTTGLTLYEAAQKSIDGMREMCRLVGIPSSIKEIGAKPEDFEMMAKNA LKDGNAFSNPRKGTVEDIVKLYQKAYDGIY > DME ID: DME1318 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKNILFVVFISMIFLFVCCNTTTNKNIIETEISDFDKILDSFQVNGSILIYDNDKNTFYS NDFDWAKNGKFSPASTFKIPNSIIAVELGIIENDTTILKWNGEQRKMDIWEKDLSFKDAF RISCVPCYQEIARKIGTIKMKEYLEKFEYKNMIFDSLTIDNFWLEGNSKISQKQQIDFLR KFYFSKFPISDRTIKIVKNIMEIERTENYILSGKTGLSSIEEKYNGWFVGYVETKSNVYF FATNVIPTDGLNVDDFISSRINVTKNALKQMNIMK > DME ID: DME1319 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKAKFFLSCMALAILFSACNTTNRTPKQKIEQQIDSFLKDKKATVGVAVLANDEIVAVYN NQIHFPLLSVFKFHVGLAVLDKMDKDHIGLDSLIEVKSSQLKPDTYSPLRDEFPDQDITI SLGELLKYTISKSDNNTCDILIEYVGGIDQVNEYVKSLGIKDCNLAATETLMHTSGDAYL NWSTPEEVVRLLNIADKQPLFATQYKDFLQATMQETSTGKDKLKGQLPADVIVGHKTGSS DRTPEGIKIADNDAGFVILPNGQKYYIAVFVMESQETDADNAAIIASISKIVYDTLNSDI Q > DME ID: DME1320 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAIPGMAVAVIYQGKPYY FTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDAIARGEIKLSDPVTKYWPELTGKQ WQGIRLLHLATYTAGGLPLQIPDDVRDKAALLHFYQNWQPQWTPGAKRLYANSSIGLFGA LAVKPSGMSYEEAMTRRVLQPLKLAHTWITVPQNEQKDYALGYREGKPVHVSPGQLDAEA YGVKSSVIDMARWVQANMDASHVQEKTLQQGIALAQSRYWRIGDMYQGLGWEMLNWPLKA DSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTGGFGSYVAFVPEKNLGIVMLA NKSYPNPVRVEAAWRILEKLQ > DME ID: DME1321 DME Name: Arylamine N-acetyltransferase (NAT) PDB ID: Not Available MNDDAAWGAPALDLPRYLHRIGLQAPPAPDLAGLSTLVRAHALTLPWENFDAVRGIPGEL TIDALQRRMIEGRRGYGCTGHVPLLAAALQRTGFRFGAASGRVLVDGGPSASTHALLIVE VDGAPHLAEVGFGAVPLAPLRLESGLEQDAGGWRYRLTAEAVGFGEEWRLDFLDPSSGQW RPQYRFALADRTWSDLRMTNFYVATSPHSPFRGRLMAVVNRPGERHVLTRDAVISTRPDG FRETVPYVAADRRAILAESFAIDLPEDEAAALAAVSGS > DME ID: DME1322 DME Name: Azoreductase (azoR) PDB ID: Not Available MAKILVIKAHPLTIEHSRTLKILDAFMTQYKVSNPEDTIETRDLYAEEFPDIDRSMMTAW GQLQNGVGFPDLTTQQQQQLSAYDSTTQQYIDADKVILANPMWNLSIPAKLQAWIDTICV AGKTFQYTETAEIPLVPGKKVLHIQTAGGFYDGKDFGAKYISGIMHFLGASDVQELAVEG MDHFPEKAEAFMQDGLERATALATKF > DME ID: DME1323 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKTNRLIILLFILLPVHALASNRFQELYTNIHQFISQQKAEVGVAIIADGKDTVTVENNR RYPLMSVFKLHQALAVGDYCKRHQISFDTLLTVDSTDLQPNTYSPLRDQYPHGGKFSLKQ LMEYTLHLSDNNACDILFKFTGGPAVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWS TPLATAEVIEALLTQTLFDKPHQEFIKEALVTCQTGTNRIVHPLQDKQVTVGHKTGTGDR NASGQLIAINDAGFVQLPNGHRYTLVVFVKDSQESMEDTEAIIAQISEMVYQAFSKP > DME ID: DME1326 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKYTFRTFFCGMGDCIFLMLENGCHTLNIMVDCGKYIDEIDNFVKTELKNKIDYLIVTHI DNDHINGLITMLTKNSDLIIGNIIYNCYQRLIKNAIPWTDKMTENVSRLYGKLPIVIDMI SQDINEEKAVTLAECILRKEEWNRTWQREYVTDESPAIQLANNMGRIIFLSPSQAALDQL DKKYRKLFWQQLYKQKEEEYDKEETIYEALMRIAQLDEDEEIKEENVNDCTINEHTLKQY ACQSLSKMDDNNMASIAFVWEHQGHRILFMGDADPTQVSKAIEEAYKDETKPIIFDLIKV SHHGSAHSTSKELMNMADSERFFFTGGAKERPSLQTLGRIITNPLPDGIEYRDIRYNRHN VILKKLADLSVEEKNSLHIKVNDNQNSYEFSY > DME ID: DME1327 DME Name: Nitroreductase (NTR) PDB ID: Not Available MNETIELLHNHRTYRQFDPDYRLSQEQVTAILTAARQAPSWMNGQAYSILVIDDPQIRQQ MVEWNPGNPHIAACSLFLLFLADLNRTKKVADEKQTPYPIDEGYQPLLIATTDASIALQS GAIAAESLGLGTVISGSVRKDSAKIAELLHLPEYVYPVAGLSIGKPIVEMKVKPRLPEEA VIHYNHYQDYSYEAIEAYDQTMTAFGEARETKPWSEKFAGFYSNRPDQGFDAFLKKQNLI K > DME ID: DME1328 DME Name: Nitroreductase (NTR) PDB ID: Not Available MNETIDLLTNHRTYRQFDSNYQLSKEQLEAILSAARQAPSWMNGQAYSILVIDDRSLRQQ LVTWNPGNPHIAESSIFLLFLADLNRTKKVAEKKQTPYLVDEGLQPLLIATTDASIALQS AAIAAESLGLGTVISGSVRKDSKAIAELLELPEYVYPVAGLSIGKPIVDMALKPRLPQEA VIHYNKYQDYSYQAIEDYDQIMTAFGEARETMPWSEKFANFWLYNLWD > DME ID: DME1329 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1331 DME Name: Nitroreductase (NTR) PDB ID: Not Available MNAILKRRSIRKYKDKKISDDIVEELLRAGMAAPSAVNEQPWQFIVLRDKETMKKITKVH EYSKMLLEADVAIVVCGDKSKELVDDFWVQDCSAATENILIEAQDKGLGAVWLGVYPIKE RVDGIKEILNLPEGITPLSVIPIGYPDEKKEPADRSNKERVHYDKW > DME ID: DME1332 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MTYSSKRRTLLLAAATAPLALTVAACASSQAAAPNEAATPDVAAAAAAAALAHLERDAGG RLGVCAIDTASGRRVAHRAAERFPFCSTFKAMLSAAVLAQSVARPGLLQQRVTYGKADLV NYSPVTEKHVGAGMTVAELCEATIQYSDNSAANLLMKLIGGPSAVTAYARSIGDDTFRLD RWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRAQLVTWLRGNKVGDKRIRA GVPAGWTVGDKTGTGDYGTTNDAGVVWAPSRAPIVLAVYYTQARADARAKDDVIADVARV VVAAFG > DME ID: DME1333 DME Name: Methylenetetrahydrofolate dehydrogenase (folD) PDB ID: Not Available MAKRLLGKEVTAALNERIKADVAALEEKGVKPTLCIIRVGENESDISYERGATKRCETLG VACEKILLPADVSQEELLATIDKVNKDDKIHGVLLFRPLPKHLNQSVIENALDPAKDVDC MTDGSMSGVFTGKNVGFPPCTPQACMEILDFYGIDCTGKKAVVVGRSLVVGKPAAMMLIK KNATVTICHTRTVDMPSVVREADIVIVAAGRAGVIDDTYLSAGQTVIDVGINVNAEGKLC GDVDFEKAEPVVDAITPVPGGVGSVTTSVLVGHVVEAAKRKFA > DME ID: DME1334 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGDVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1335 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLTDSISQIVSACPGEIG VAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISLDTLVNINRDKLDPKTW SPMLKDYSGPVISLTVRDLLRYTLTQSDNNASNLMFKDMVNVAQTDSFIATLIPRSSFQI AYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIA APLLDKEGVVIAHKTGSGYVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQAS QYVAHISAVVYSLLMQTSVKS > DME ID: DME1336 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MFKKLVFLGILLLPLILWIIWSNTSKNSSNSSMIYVEKNNENSEKVLNEDLSKYFSGYDG CFVLYDKNENKYLIYNEAKSEKEISPCSTFKIVNALIGLDTNVLQDENTIFKWNGTKYAI EEWNKDQTLSSAVANSVVWYFQDVASKVGEERMQEYLSKIDYGNKDISGGLTKFWLQSSL KISPMQQVEILRNMYDYKLPFSRRNIDIVKKVLKISEQNGIVLSGKTGSGTDGNKSINGW FIGYVESDNDVFFLAVNIEGKDNATGVLAEQIAKNILKDKNIL > DME ID: DME1337 DME Name: D-alanylalanine synthetase (ddl) PDB ID: Not Available MKIVVLAGGLSTERDVSFKTGDMVAKALRENGHQVILLDVFMGYSDKKEDLTGIFDRSEE VSVKVSGIPETAPDLAKVKASRKDQSDNFFGPNVIELCQMSDIVFMALHGENGENGKIQA AFDLFGIRYTGTGYLSSALAMDKEMSKKLFLSAGIPAPKGASMKKADCSDDITKLGIQFP CVVKPCCGGSSIGVSIAHNAEEYKAALDEAFRWEENLIVEEYVKGREFSVGVIEGKALPI IEIAPVQGFYDYKNKYKAGSAVETCPAELSEAVTEKMQHYAEQVAQVLGLDTYSRTDFLL DENENIYCLEANTLPGMTPTSLLPQEAQVVGVNFNELCEKLIQISLDKYEK > DME ID: DME1338 DME Name: Linoleate 10-hydratase (10-LAH) PDB ID: Not Available MVKSKAIMIGAGLSNMAAAVYLIQDGHWDGKDITFYGVDMHGANDGGATTDFTNEYWNKN HPMANTTGYVARGGRMLNYRTYVDLMDLLDRIPSVTEPGMTAAEDTRDFDVKHRTYDIAR LMQGGKGIINAGKLGFNNKDRTLLTKLIMMPDSEETKLDNVSIAEYFKDDPHMFQTNFWY MWETTFAFRTQSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQFESMILPLIKYLQGQG VTFIDNKIVKDWQFKDTPMQDEITVTGLVIEDAQTGETEEVEVDEETAVIFTNGSITDSA TMGDYNTPAPENMDYGVSASLWKKATERFYNLGTPDKFFNDRNASEWVSFTLTTKNHLFL NEIVRITTQEPGNALNSFLSTTPITPLNQKDVNMSIVVHHQPHFTTQQPNETVLWGYFLY PRRQGEFVNKPYIKMTGKEMAQELIGQLSKVDPGPGNIKDKEKEILDSIVNNIPVYMPYA SALFNNRAKSDRPEVLPKHSTNLAFTGEFAEQPYQMIFTEQSAVRSGEIAAYHFAGVPMD NLVKTPRYDKDPKTLLKATKKMFD > DME ID: DME1339 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MAMLYGKHNHEAEEYLEPVFGAPSEQHDLPKYRLPKHSLSPREADRLVRDELLDEGNSRL NLATFCQTYMEPEAVELMKDTLAKNAIDKSEYPRTAEIENRCVNIIANLWHAPDDEHFTG TSTIGSSEACMLGGLAMKFAWRKRAQAAGLDLNAHRPNLVISAGYQVCWEKFCVYWDVDM HVVPMDEQHMALDVNHVLDYVDEYTIGIVGIMGITYTGQYDDLAALDKVVTHYNHQHPKL PVYIHVDAASGGFYTPFIEPQLIWDFRLANVVSINASGHKYGLVYPGVGWVVWRDRQFLP PELVFKVSYLGGELPTMAINFSHSAAQLIGQYYNFIRFGMDGYREIQTKTHDVARYLAAA LDKVGEFKMVNNGHQLPLICYQLAPREDREWTLYDLSDRLLMNGWQVPTYPLPANLEQQV IQRIVVRADFGMNMAHDFMDDLTKAVHDLNHAHIVYHHDAAPKKYGFTH > DME ID: DME1340 DME Name: Nitroreductase (NTR) PDB ID: Not Available MIILFISLQKKDMMDTVKNRRTIRKYQQKDITPDLLNDLLETSFRASTMGGMQLYSVVVT RDAEKKEILSPAHFNQPMVKEAPVVLTFCADFRRFCKYCQERNAVPGYGNLMSFLNAAMD TLLVAQTFCTLAEEAGLGICYLGTTTYNPQMIIDALHLPELVFPITTVTVGYPAESPKQV DRLPIEGIIHEESYHDYTAEDINRLYAYKESLPENKLFIEENQKETLAQVFTDVRYTKKD NEFMSENLLKVLRRQGFMD > DME ID: DME1342 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLISRSIPTYASELT NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK PSKPSN > DME ID: DME1344 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MSETHSTTENNNSHCCDNTCGNADDRVVPDSVEINPLFARPKEAQAFSKFTIPQKGSLPE TAYQVVHDEAMLDGNARLNLATFVSTWMDDHANRLYMEAADKNMIDKDEYPKTAEVESRC WHMLADLWHAPDPMNAIGTSTIGSSEACMLGGLALKRRWKEAREKADLPTDRPNLVMSSA VQVCWEKFCNYFDVEPRYVPISEDHKVLDGHDLDKYVDENTIGVVAIMGVTYTGMYEPVE QISEALDRIEERTGLDVRIHVDGASGGMIAPFIQPDLAWDFRVKRVYSISTSGHKYGLVY PGLGWIVWRETADLPESLIFKVSYLGGEMPTFALNFSRPGAQVLLQYYMFLRLGFDGYRR VQQTSHDMAKYLSGEIEQMDDFTLWNDGSDIPVFAWMLNDKPDRKWNLYDLQDRLRMKGW LVPAYPMPVDLTQVTVQRIVVRNGFSHDMAEAFIKDLKSCVKYLDGLRSPMPSEARASEF HH > DME ID: DME1345 DME Name: Azoreductase (azoR) PDB ID: Not Available MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLELYRDDIPEIDEELLSGW EALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANALWNLNIPTKLKAWFDTVNV AGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQYVKGILNFVGIDQVDQLFIEG IDYDPDRADELMQNALDKAAALGKSF > DME ID: DME1346 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available MSDMHFSTTASSTCCGNDTRDADRLGSVEINPLFARPKEARSFPKNRIPDTGSLPETAYQ VVHDDAMLDGNARLNLATFVGTWMDDYANRIYMEAADKNMIDKDEYPKTAEIEDRCWRML ADLWNNLDIDHAIGTSTIGSSEACMLGGLALKRRWVKARKAAGLPTDKPNLVMSSAVQVC WEKFCNYFDVEPRFVPISEEHKVLDGYDLDKYVDENTIGVVAIMGVTYTGMYEPVQHISD ALDRIQEKTGLNIHIHVDAASGGMIAPFIQPDLAWDFRVKRVVSISTSGHKYGLVYPGLG WVVWRSTADLPESLVFKVSYLGGEMPTFALNFSRPGAQVLLQYYMFLRLGVEGYRRVQQA SHDVAKYLSSEIAAMDDFTLWNDGSDIPVFAWMLKDKPGRKWNLYDLQDRLRMKGWLVPA YPMPVDLTDVTVQRIVVRNGFSHDLAESFLKDLKACVAYLDNLQAPMPSEAHVSGFHH > DME ID: DME1347 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKLRYTLIGVLCFSINIVLQAQQQALEGKIAGFLKGKKATVGVAVLTDKDETILHNNEVH YPLLSVFKFHVALAVLDKMNREEIPLKHIVHVKASQLQPNTYSPLRQKHSGQDLDISLGE LLQYSISLSDNNACDILIEYTGGIGHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWS TPSEMVRLLKMADEKDLFAPVYRDFLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRN LKGVKMADNDAGIVIMPGGKKYYIAVFVTDSSETDEENAAIIAHISRMVYDEMK > DME ID: DME1348 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKAKFFLSCMALAILFSACNTANRTPKQKIEQQIDSLLKDKKATVGVAVLANDETVAVYN NQIHFPLLSVFKFHVGLAVLDKMDKGHIALDSLIEVKSSQLKSNTYSPLRDKFPDQDITI SLGELLKYSISQSDNNACDILIEYAGGIDQVNEYVKSLGIKDCNLAATEDLMHTSGDAYL NWSTPEEVVRLLNIADKQPLFGTQYKDFLQAIMQETSTGKDKLKGQLPADVIVGHKTGSS DRTPEGIKIADNDAGFVILPNGQKYYIAVFVMESQETDTDNAAIIASISKIVYDTLNSDI Q > DME ID: DME1349 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MPRSVSSSSYPHEYSRHASHAAKPHRPHPQPCKPRQLRLDWQALLRFFQNLSERLPQRHH GKVKILKGSVYTRRRIVVGCLGVLLLVELFQLFWPSDKFFPLATLDGHAVGGQSSQQAAE TLNAATLKRTVKLTDKTTGTTVSLTAKQAGITVDYTDRAKAAAKHSVVKRIVPFSWLFVH STTSDSLPDALGTSDKQAHEDMRNASVQGTKGELKIVSAAPGYTFTSADIRSAAGSSFSS SATGDLAAATIEMGIVSPTVSDDTAEQLLDTLNKALSKDVTFTYEDGTWTVPAKKIINTV STTVNAQDNTKLDVTISESKLMRQLKSKGIALKVAKKAADAGVTPATIAVKGSAYQVIDA SATAASLSGMLASGQNAPVAVSTKDFSNVELYEGLPASGTIEEKLQQLFGDADYEVAVYD LKTGKSKIQIDADTAMTSASTYKLFIAYSMIHAVETGQVTWDSALNGMTLSSCMATMIIN SDNSCPEAWLARYGFSTVTQQAHDIGAANTNFVPYGMTTTANDLATVLKGFYSNSIASPD STDQLFSLMETQVYREGIPAGIGSDGVVQDKVGFMDGLLHDAAIVRSDKGDYAMVIMTDG SSWNKIAQASLLIYESL > DME ID: DME1350 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MLYPLLTKTRNTYDLGGIWNFKLGEHNPNELLPSDEVMVIPTSFNDLMVSKEKRDYIGDF WYEKVIEVPKVSEGEEMVLRFGSVTHQAKIYVDGILVGEHKGGFTPFEVLVPECKYNNEK IKVSICANNVLDYTTLPVGNYSEIIQEDGSIKKKVRENFDFFNYAGVHRPLKLMIRPKNH ISDITITSRLSDDLQSADLHFLVETNQKVDEVRISVFDEDNKLVGETKDSRLFLSDVHLW EVLNAYLYTARVEIFVDNQLQDVYEENFGLREIEVTNGQFLLNRKPIYFKGFGKHEDTFI NGRGLNEAANLMDLNLLKDIGANSFRTSHYPYSEEMMRLADRMGVLVIDEVPAVGLFQNF NASLDLSPKDNGTWSLMQTKAAHEQAIQELVKRDKNHPSVVMWVVANEPASHEAGAHDYF EPLVKLYKDLDPQKRPVTLVNILMATPDRDQVMDLVDVVCLNRYYGWYVDHGDLTNAEVG LRKELLEWQDKFPDKPIIITEYGADTLPGLHSTWNIPYTEEFQCDFYEMSHRVFDGIPNL VGEQVWNFADFETNLMILRVQGNHKGLFSRNRQPKQVVKEFKKRWMTIPHYHNKKNSVK > DME ID: DME1351 DME Name: VanG ligase (vanG) PDB ID: Not Available MQNKKIAVIFGGNSTEYEVSLQSASAVFENINTNKFDIIPIGITRSGEWYHYTGEKEKIL NNTWFEDSKNLCPVVVSQNRSVKGFLEIASDKYRIIKVDLVFPVLHGKNGEDGTLQGIFE LAGIPVVGCDTLSSALCMDKDRAHKLVSLAGISVPKSVTFKRFNEEAAMKEIEANLTYPL FIKPVRAGSSFGITKVIEKQELDAAIELAFEHDTEVIVEETINGFEVGCAVLGIDELIVG RVDEIELSSGFFDYTEKYTLKSSKIYMPARIDAEAEKRIQEAAVTIYKALGCSGFSRVDM FYTPSGEIVFNEVNTIPGFTSHSRYPNMMKGIGLSFSQMLDKLIGLYVE > DME ID: DME1352 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MKKTLLTICLTWMCFSLSAQKIIDLSGKWSFSIDRQDNGEKEKWFSHTLNDCINLPGSMP EKLKGDEVTAKTQWTGSLYDSSYYYNPYMEKYRKEGNIKFPFFLTPDKHYVGAAWYQKEV NIPADWKGERILLFLERPHIETTVWVNGQKTGMQNSLCVPHQYDITRYVRPGKCTITIRV DNRIKEINVGPDSHSITDQTQGNWNGIVGRICLQTTPKTYFDDIQIYPEPEQKLARVKVV IKGAGITKIKLSAESFNTDKKHIVPAIQQEIKLNKGVTETEMVLPMGNDMLLWDEFHPAL YKLKAEVTNGKKTEIKEIQFGMRRFEIKGKWFYVNGRKTQLRGTVENCDFPLTGYAPMDV ESWERVFRICRSYGLNHMRFHSFCPPEAAFIAADRVGFYLQPEGPSWPNHGPKLGLGQPI DTYLMNETIALTKEYGNYASYCMLACGNEPSGRWVEWVTKFVEYWEKKDPRHVYTGASVG NGWQWQPRNQYHVKAGARGLTWSRRQPSTQDDYRFQNHLDTVKQPYVSHETGQWCAFPNF NEIRKYTGVNKAKNFEIFKDILADNHMSDQAHLFMMASGKLQALCYKYEIEKTLRTPDYA GFQLLALNDYSGQGTALVGVLDVFFEEKGYINSAEWRRFCSPTVPLMRTDKFVYNNNEIL KADIEVAHFGAKTLKQAEIVYTLKDEYGKVYAQGTLATQDIPIGNLNHTGSLEFPLTDIQ EAKKLNLEIRITGTEAVNDWNFWVYPAQVTIAEGKVYTTDTLDSKALEILQHGGNVLITA AGKVSYGKEVVQQFTPVFWNTSWFKMRPPHTTGILVNPKHPLFRQFPTEYHSNLQWWELL NHAQVMQFTHFPPAFQPTVQSIDTWFISRKIGMLFEANVLNGKVLMTSMDITSQPEKRIV ARQMHKAILDYMNSDQFRPQFTVTPQQISELFTKTAGDIKSYTNDSPDELKPKIN > DME ID: DME1353 DME Name: Gamma-glutamylcyclotransferase (GGCT) PDB ID: Not Available MAVTREDLEQNRLRAALGDSPVASTLLTEAALEASLTSTLARLSAPPCDGQDAWVFGYGS LIWNPMIFHTEATCATVHGYHRGFYLYSRINRGTWDNPGLVLGLDRGGSCHGVAFRVPRA HAEREFRVLWRREMMTGAYLPRWLPTEIHGERILALAFVMNRTHEAYAGRLPDERVLGCL HKAVGLYGPAREYLQRTLIGLASNGLHDPYLDRLWQRLQAMDAANAPSQAEDATGTGPSP DPYLSA > DME ID: DME1354 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MFRILFSALCAFALNASANNIPTASPEEVGMSLARLRAADEVILRAIRDHRTPGAVLAVV RHGKMAYLKAYGNRQTYPTTQPMTTQTVFDMASCTKPMATAISAMLLVERGKLRLSDPVS TYLPEFKNWHGEGKDSVTIRVEDLLTHTSGLPPYAPVKTLAEANGKPNPAKLMAYIARCK RDFKPHTDMQYSCLNYITLQNIVERITGQSLRTFAANNIFIPLGMNHTDFLPCAPDKSGK LANTSQPRWVTNGEQASLTPIAPTERQPNGTVKLGQVHDPLACTLNGGVSGNAGLFSSAE DVATLCAMLQNGGEWGGKRILSPLTVKAMRSIPQNFNSFGRSLGWDVSSAYASNQGDLLS DEAYGHTGYTGTSIVIDPVNDLSIILLCNSVHPVDTTNVIRLRAQVANAVAASITNEAAA FPGYYYVRMRTFEAEPPIRSTDIVMLGNSLTEGGRDWAEKLGKPNVRNRGISGDVAMGID ARLFQITPHKPAKIFLLVGINDVSHDLTVDSIVTNIRLLVEHIHAQSPKTKLVLQSLLPI RESTGRWKRLQGKTDMIPQINARLEALAREKGLTFINLFPHFTEPGTNVLRSELTYDGLH LSKAGYDVWVKLLKPHL > DME ID: DME1422 DME Name: Molybdopterin-dependent enzyme (molD) PDB ID: Not Available MNPPEEDPGTPEPRIGPVPEKKPAFRPYHHPAAGWGAAKSVTRFLTKERELIDGPRAIAK MNHENGGFDCPGCAWPDDIKGLKLDICENGIKHVTWEMTRKRVGREFFAAHSVSELSGWS DFRLEDQGRLTEPMVYDPESDHYEPISWKDAFELVGRTLRGLDSPHQASFYTSGRLGNEA TFLYQLWARELGTNNLPDCSNMCHEASGRALQAALGTGKGTCDLKDWESADALFIMGVNA ASNAPRMLTALAEAYRRGAQVVHVNPLVEAAATRTIIPHDIADMAMFKSTRTSTLNLQVR IGGDMAFLRGVAKAVLKQAETDPKALDREFIDRYTDGFDAYRALCEATGWDEIERQSGLS RDAVLAAARVYGEADRSIISWCLGVTQHDHGVDTIREIVNVLLLRGNLGREGAGPSPVRG HSNVQGNRTCGINHRPPEEFLDRLADACGIEPPREHGLDTVGTIRAMHDGDVKVFVGMGG NFALAAPDTPYTYEALRNCDLTVQVSTKLNRSHLVHGRAALILPCLGRTEKDEQRAGLQS TSVEDSMSMVHLSVGMKRPASRHLLSEPAIIAGMARATLPGSSTPWEWYVEDYDRIRDSM ARVVEGFEDCNRRVRLPLGFRIRQPARELVFMTESGRAEFSTAPLPDVVPEPGTLALGTM RSHDQWNTTIYSDDDRYRGITNLRTLVFMNKDDMRERGVEEFGPVDITSTARDGSRRRVE GYLAVPYDIPRGCAAGYMPEMNVLCALVDYSTQSDQPLMKHVKVTITPSG > DME ID: DME1442 DME Name: Cytochrome P450 130A1 (cyp130) PDB ID: 2UUQ; 2UVN; 2WGY; 2WH8; 2WHF MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAAR DHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTV RKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVD GATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTM VTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRD VTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAA RMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS > DME ID: DME1461 DME Name: Homoserine-O-transsuccinylase (metAA) PDB ID: 2H2W MPINVPSGLPAVKVLAKEGIFVMTEKRAIHQDIRPLEILILNLMPDKIKTEIQLLRLLGN TPLQVNVTLLYTETHKPKHTPIEHILKFYTTFSAVKDRKFDGFIITGAPVELLPFEEVDY WEELTEIMEWSRHNVYSTMFICWAAQAGLYYFYGIPKYELPQKLSGVYKHRVAKDSVLFR GHDDFFWAPHSRYTEVKKEDIDKVPELEILAESDEAGVYVVANKSERQIFVTGHPEYDRY TLRDEYYRDIGRNLKVPIPANYFPNDDPTKTPILTWWSHAHLFFSNWLNYCIYQKTPYRL EDIH > DME ID: DME1465 DME Name: Cytochrome P450 102D1 (cyp102) PDB ID: 1BU7; 1BVY; 1FAG; 1FAH; 1JME; 1JPZ; 1P0V; 1P0W; 1P0X; 1SMI; 1SMJ; 1YQO; 1YQP; 1ZO4; 1ZO9; 1ZOA; 2BMH; 2HPD; 2IJ2; 2IJ3; 2IJ4; 2J1M; 2J4S; 2NNB; 2UWH; 2X7Y; 2X80; 3BEN; 3CBD; 3DGI; 3EKB; 3EKD; 3EKF; 3HF2; 3KX3; 3KX4; 3KX5; 3M4V; 3NPL; 3PSX; 3WSP; 4DQK; 4DQL; 4DTW; 4DTY; 4DTZ; 4DU2; 4DUA; 4DUB; 4DUC; 4DUD; 4DUE; 4DUF; 4H23; 4H24; 4HGF; 4HGG; 4HGH; 4HGI; 4HGJ; 4KEW; 4KEY; 4KF0; 4KF2; 4KPA; 4KPB; 4O4P; 4RSN; 4WG2; 4ZF6; 4ZF8; 4ZFA; 4ZFB; 5B2U; 5B2V; 5B2W; 5B2X; 5B2Y; 5DYP; 5DYZ; 5E78; 5E7Y; 5E9Z; 5JQ2; 5JQU; 5JQV; 5JTD; 5OG9; 5UCW; 5XA3; 5XHJ; 5ZIS; 5ZLH; 6H1O; 6H1S; 6IAO MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIK EACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMM VDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVR ALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLN GKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLV DPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQ LHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLK HFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHN TPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGH PPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIAD RGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMH GAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFG LDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVE LEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDE KQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLI MVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIIT LHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYAD VHQVSEADARLWLQQLEEKGRYAKDVWAG > DME ID: DME1466 DME Name: Cytochrome P450 154C2 (cyp154) PDB ID: Not Available MTRIALDPFVRDLDGESAALRAAGPLAEVELPGGVHVYAVTHHKEARALLTDSRVVKDIN VWNAWQRGEIPADWPLIGLVNPGRSMLTVDGPDHRRLRTLVAQALTVKRVEKLRAGIEAL TNASLERLAALPAGEPVDLKAEFAYPLPMNVISELMGVDAADHPRLKELFEKFFSTQTPP EEVPQMMADLGTLFTKIVEEKKANPGDDLTSALIAASEDGDHLTDEEILNTLQLIIAAGH ETTISLIVNVVEALAIHPEQRKKVLSGEIPWEGVIEETLRWNTPTSHVLIRFATEDIEVG DKVLPKGEGLVVSFGALGRDEEQYGPTAGDFDATRTPNRHIAFGHGPHVCPGAALSRLEA GIALPALYERFPELDLAVPAAELRNKPIVTQNDLHDLPVKLGCPFGHDA > DME ID: DME1471 DME Name: L-malate:NADP(+) oxidoreductase (maeB) PDB ID: Not Available MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVAAPCLEIEKDPLKAYKY TARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFAGIDVFDIEVDELDPDKFI EVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFHDDQHGTAIISTAAILNGLRV VEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVVCDSKGVIYQGREPNMAETKAAY AVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKKMARAPMILALANPEPEILPPLAKE VRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDVGATAINEEMKLAAVRAIAELAHAEQS EVVASAYGDQDLSFGPEYIIPKPFDPRLIVKIAPAVAKAAMESGVATRPIADFDVYIDKL TEFVYKTNLFMKPIFSQARKAPKRVVLPEGEEARVLHATQELVTLGLAKPILIGRPNVIE MRIQKLGLQIKAGVDFEIVNNESDPRFKEYWTEYFQIMKRRGVTQEQAQRALISNPTVIG AIMVQRGEADAMICGTVGDYHEHFSVVKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYV NDEPDAEELAEITLMAAETVRRFGIEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAP ELMIDGEMHGDAALVEAIRNDRMPDSSLKGSANILVMPNMEAARISYNLLRVSSSEGVTV GPVLMGVAKPVHVLTPIASVRRIVNMVALAVVEAQTQPL > DME ID: DME1472 DME Name: Cytochrome P450 21A2 (cyp21) PDB ID: Not Available MTEKTMPGPLPPVRHWPALDLKGVDFDPVLSELMREGPVTRIQLPNGEGWAWLVTRHDDV RMVANDPRFGREAVVDQPVTRLAPHFIPARGAVGFLDPPDHTRLRRSVAAAFTARGVERV RDKARRTLDVMVDELLRIGPPADLTEAVLSPFPIAVICELMGVPADDRRGMHTWTQLILS SAHGAEVSEKAKDEMGAYFRKLIGARNDSRDEDVTSLLGAAVGRDEIDLEEAVGLAVLLQ IGGEAVTNNSGQMFYLLLTRPALADRLRSDPRIRPQAIDELLRYIPHRNMVGLSRIARED VEIRGVQIRAGDPIYVSYLAANRDPEVFPDPEHIDFGRSPNPHVAFGFGPHYCPGGMLAR LESELLVEALVDRLPGLRLAVPPSQVPFRKGALIRGPEALPVTW > DME ID: DME1473 DME Name: Azoreductase (azoR) PDB ID: Not Available MDRKGFLKSTMIATGSLLLGGAGICRFLNDKEPADGPFPRTIEKIHCGNMKKVLVIMSAG TKLGNTDRLTDAYIKGLVERGHSVTKVYLGSMRIEGCRGCGVCQRLAHQCAVRDGMQDIY PLFAECDTVVMASPLYFWTITSQLKAFIDRLYAISADDKYPQKDTVLLMTAGDDNENTFD QPKQYFRLLSQALGWNEVGIYCAGGCTGCEKLARQIDKVHLENVYKMGLEL > DME ID: DME1474 DME Name: Azoreductase (azoR) PDB ID: Not Available MDRKGFLKSTMIATGSLLLGGAGICRFLNDKEPADGPFPRTIEKIHCGNMKKVLVIMSAG TKLGNTDRLTDAYIKGLVERGHSVTKVYLGSMRIEGCRGCGVCQRLAHQCAVRDGMQDIY PLFAECDTVVMASPLYFWTITSQLKAFIDRLYAISADDKYPQKDTVLLMTAGDDNENTFD QPKQYFRLLSQALGWNEVGIYCAGGCTGCEKLARQIDKVHLENVYKMGLEL > DME ID: DME1475 DME Name: Azoreductase (azoR) PDB ID: Not Available MAKILVIKAHPLTIEHSRTLKILDAFMTQYKVSNPEDTIETRDLYAEEFPDIDRSMMTAW GQLQNGVGFPDLTTQQQQQLSAYDSTTQQYIDADKVILANPMWNLSIPAKLQAWIDTICV AGKTFQYTETAEIPLVPGKKVLHIQTAGGFYDGKDFGAKYISGIMHFLGASDVQELAVEG MDHFPEKAEAFMQDGLERATALATKF > DME ID: DME1476 DME Name: Azoreductase (azoR) PDB ID: Not Available MKFVGLVGANYDQSYNRKLLEFIRRHFKIKFELEVLEIDEVPMFNQDEKWDESFQLRLLN NKITRADGVIIATPEHNHTISAALKSVLEWLSFEVHPFENKPVMIVGASYYDQGTSRAQV HLRKILEAPGVNAYTLPGNEFLLGKAKEAFDLEGNITNEGTINFLEQCLDNFIQYVGVVS KLKKPKPIEPEDLDCNNPIATTVTEVDPDDPEWVEKVAEITGAVSGDTYVKLDHGILTVN QIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMFAKRVPPQSGSRMSTVHGSLPPARM KNVEWVIGTLRNGNQEYVRTIVPGSPEGVINTHNYQAMYYDDGSYAGINEIVFNFKPWLD WYLETTGQRLVGGSGPFAPAAASHGGSDATSGASDAGGHGGDAAPAADATSGASSY > DME ID: DME1477 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MHSKQKGTFPTTPRILAAFLMAFFLMVSCGCSTKIGQPVLPDSEGNGSETETPDDNKPDE NKPGENEQTPDSEGYVLMWSDEFDSNSLDTGKWRIEVNGNGGGNAELQYYDESGISLGKD SEYGNSALKITAKREQRNGKAFVSGRLNTSGHFQFCYGKVEGRIRLPRTANGLWPAFWLL GADFQTNSWPRCGEIDIMEMGNAEGIKKGTQDRFFNGACHWGYYKGSAYPNYAHSTTNSY SIQDGNYHTYTLIWTPQSVKMYLDRDLHPNASPYYEMDIVNKDDDWGVGYYFHHNFFIIL NLAVGGYFTGILQPEGITALPNNGDSATMFVDWVRVYQKKQ > DME ID: DME1479 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MHSKQKGTFPTTPRILAAFLMAFFLMVSCGCSTKIGQPVLPDSEGNGSETETPDDNKPDE NKPGENEQTPDSEGYVLMWSDEFDSNSLDTGKWRIEVNGNGGGNAELQYYDESGISLGKD SEYGNSALKITAKREQRNGKAFVSGRLNTSGHFQFCYGKVEGRIRLPRTANGLWPAFWLL GADFQTNSWPRCGEIDIMEMGNAEGIKKGTQDRFFNGACHWGYYKGSAYPNYAHSTTNSY SIQDGNYHTYTLIWTPQSVKMYLDRDLHPNASPYYEMDIVNKDDDWGVGYYFHHNFFIIL NLAVGGYFTGILQPEGITALPNNGDSATMFVDWVRVYQKKQ > DME ID: DME1480 DME Name: Alpha-L-rhamnosidase (lrA) PDB ID: Not Available MSFKRSLIIVLSFLLTFSLLYPVTETVEASPPGTITNLQVEYMENPIGVDSENPRFSWNM VSNVRGAKQLAYELVIADSEKNLKQGEYVWSSRKVTSSQSVNVKYTGEAKLTASTRYFWK VKVWDQDNKVLESKQNAFFETGLMSKDGTTNWDGAQWITNNKAATDPVNVTLFRTEQKVT NKPIQNAQLYISSLGIYEAFINGKEVQLLQGQEQAVDETFNPGWTDYNSYVNYQAYDVTS YLSNKSHLSLGVMVGKGWYAGRIGQVGQYTKVSGNKLALLAKLVITYKDGSTDVIVTNES NWKSSEKSPIKSNDFFDGETYDAIVAKEIEGWNNVKYDDSEWSPVSSFIYKGEVKGSRAA AARVAEEYTQQPIGAYKYSEIEQSVQNGGESSYDFGHAITTKVKPNSTIHLKAGEILIVD MGQNMAGVPNIKVSGDTGSTVTMRFAEMINDGKKNPKIMSGGSDGPKDTLYRKALTSAAQ TDKYILSGQGVEEYQPVFTFHGYRYMEVTADADLRIHSAEGKVITSVKDQTGDITTSNSD VNKLFSNVLWGQRSNYLSIPTDSPQRAERAGWTGDAQLFAQSAVYNYNDFSFLENYSEIM DTHNKNNNGIYGSIMPGAFVGFFANTVASGWSDSGIIIPWVLYQQTGDTTVIEKNFAQME KYMDYVEKSGYNTGLFGDWLAFQATSTVYLNTIYRAYDAQLMAKMAKVIGNETAVDKYEE LYAKTKSDFVNKYFDDKGNLLTASADNFTQSRHGYPGADNAQTGLLWALKLGLYETEQQR ETMVQNLTANIKNEGSLIRPGQPENTLAVGFLGVNVLLPTLSDIGDNDLAYTLLLQDEMP SWLYSVKNGATTIWERWNSYSIEDSFGDSGMNSFNHYSYGAVAEWMYKYMAGISNDPEKP GFQHFVLQPTIDGENRISWVNGSYDSVYGEIKSNWKVENGTFKYQVTIPANTSATLAIPA TNVNEVTEGGVSLSKAKGIKVIEVKDGKVYCEVSSGTYDITSKVN > DME ID: DME1481 DME Name: Alpha-L-rhamnosidase (lrA) PDB ID: Not Available MNLKLKFILVYLSLCASAYTIQAQNIQYDPLLDPAVEIPDTPVRNGNGEYIWYPGQLSAH LQQKRLKESEKRCVNVGYPGKFYAPVYHASFCKEVNLPAETLMEWTSTGKVKVSVNGKEA GNSDKSSLTLPKGKSTLLFKVETDNDLPAIKVSFNGEVSTDHWKASMDGTEWNIAETSPV FGTAGRMPLDDPETEVTIHPVSILPIRNATVENQKIKIQKNGYILVDFFHIEVGKVSFTA KGEGKLTAFVGESPEEALNENTKLFEQYPIESYSLTEGEQQIILPERAVRYLKIFSDKEC EISDVKFKAKIWPVDFLMSFECNDERMNNIWNASVASLHTSTHGFYLDGIKRDYLPWSMD AVLSTFAGDYLFGDEQVSRNSLSVAMLPLNPQKTDLGIPDYPLHALIGFNHYYQRYGDFN TILSYRDRIEQLLKLYETLQDERGFISANVGVSWGFVPGWATRRGPDKKGTPTYAQIMLY YNYKIGADFSEKWGDKKSAKYYRMKSEDLKKSIIKHFWNEEQGLFINGYTKDGKLDTVIS HHAQYWAILADIFPKERYDHLFEVLPTIPYYHDYVSYEKGYEFLAYSKAGKVREMWNFLF TVFGDWLAQGHTRFPENFSYKKSKDEQLIFYKRPYGLSLCHGANGVPGVVAVLNGIAGFS QSPTQPNHYTIRPELMDLEWANIEFPVKEGKIKLKLSKEGKNQIEIPDGCKVDFINQNKV KKTFTKKGSYSM > DME ID: DME1484 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MFFFKKSASTFIFLLCLPLNSFASQESNGVEQMRELETSFGGRIGVYILNTKNGKEFSYR QDERFPLCSSFKAFLAASVLKRTQDKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQT LAKAAIQYSDNGASNLLMERYIGGPEGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDT STPKAVAISLNNIAFGSVLDAKNKSLLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGL YGTANDIAILWPDANSPAVMAVYTTRPNQNDKHDETVIKNAAKIAINAVYGSTK > DME ID: DME1485 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKIVILSCFIAFAFVVLFPRSFIFAAEETEHYETVIDKVADAYIGKSVPGACVIVSEHG EIVFSKAYGYADLEKNIPMDPENTVFEWGSISKTFIWVGVMQLNEEGKIDLDADIRNYLP KGFLKNLHYDTPITMRHLMNHTAGFEEQLINLRYFESDKEFTLAEVLSSHQPEQVFSPGK VSAYSNWGAALAAFIVERVSGQNYKEYVNEHILKPLDMNNTSIGPFQNDNPTILARKAVG YSFFEKGFRKEPNMYLRMYPAGGMNGSAGDLLNYAQELAKNNDKDNLLFNNPHTKKEMFT ETYRSYGANSGLSHGFWQYANNPEMHGHEGGTYGFKTQIWVEPKNERAILILTNVMETEF CSEIMEKIAYTEADEKKIKENLDLKMLSGDYLPARSALKNVGKIQGKKQMISIRVTDGNR LCLTMPFEDKKQYYEQIDSNIFFCKDASPEEKILAFNINDGKVHSMSFRLAHDYIPATNT QGKIAFLFSLGTYISTTLLFLTLLIICIISTLQRWKRCMRHHIYLYICGAMLGISGITGM AHWFSIYEILAHELMIIIIAGWCFSIIGILCGGYAIFKERSIKNSGLLLIFIAQIFSAYY LGFLTVV > DME ID: DME1488 DME Name: Heparin lyase (hepB) PDB ID: 2FUQ; 2FUT; 3E7J; 3E80 MKRQLYLYVIFVVVELMVFTTKGYSQTKADVVWKDVDGVSMPIPPKTHPRLYLREQQVPD LKNRMNDPKLKKVWADMIKMQEDWKPADIPEVKDFRFYFNQKGLTVRVELMALNYLMTKD PKVGREAITSIIDTLETATFKPAGDISRGIGLFMVTGAIVYDWCYDQLKPEEKTRFVKAF VRLAKMLECGYPPVKDKSIVGHASEWMIMRDLLSVGIAIYDEFPEMYNLAAGRFFKEHLV ARNWFYPSHNYHQGMSYLNVRFTNDLFALWILDRMGAGNVFNPGQQFILYDAIYKRRPDG QILAGGDVDYSRKKPKYYTMPALLAGSYYKDEYLNYEFLKDPNVEPHCKLFEFLWRDTQL GSRKPDDLPLSRYSGSPFGWMIARTGWGPESVIAEMKVNEYSFLNHQHQDAGAFQIYYKG PLAIDAGSYTGSSGGYNSPHNKNFFKRTIAHNSLLIYDPKETFSSSGYGGSDHTDFAAND GGQRLPGKGWIAPRDLKEMLAGDFRTGKILAQGFGPDNQTPDYTYLKGDITAAYSAKVKE VKRSFLFLNLKDAKVPAAMIVFDKVVASNPDFKKFWLLHSIEQPEIKGNQITIKRTKNGD SGMLVNTALLPDAANSNITSIGGKGKDFWVFGTNYTNDPKPGTDEALERGEWRVEITPKK AAAEDYYLNVIQIADNTQQKLHEVKRIDGDKVVGVQLADRIVTFSKTSETVDRPFGFSVV GKGTFKFVMTDLLPGTWQVLKDGKILYPALSAKGDDGALYFEGTEGTYRFLR > DME ID: DME1489 DME Name: VanB ligase (vanB) PDB ID: Not Available MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGITKNGVWKLCKKPCTEWE ADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCGEDGAIQGLFVLSGIPYVG CDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEAGALTYPVFVKPARSGSSFGV TKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAVMGNEDDLIVGEVDQIRLSHGIF RIHQENEPEKGSENAMITVPADIPVEERNRVQETAKKVYRVLGCRGLARVDLFLQEDGGI VLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDSLITLALKR > DME ID: DME1495 DME Name: Glucansucrase (gtf106B) PDB ID: 3HZ3; 3KLK; 3KLL; 4AYG MEIKKHFKLYKSGKQWVTAAVATVAVSTALLYGGVAHADQQVQSSTTQEQTSTVNADTTK TVNLDTNTDQPAQTTDKNQVANDTTTNQSKTDSTSTTVKNPTFIPVSTLSSSDNEKQSQN YNKPDNGNYGNVDAAYFNNNQLHISGWHATNASQGTDSRQVIVRDITTKTELGRTNVTNN VLRPDVKNVHNVYNADNSGFDVNINIDFSKMKDYRDSIEIVSRYSGNGKSVDWWSQPITF DKNNYAYLDTFEVKNGELHATGWNATNKAINYNHHFVILFDRTNGKEVTRQEVRDGQSRP DVAKVYPQVVGANNSGFDVTFNIGDLDYTHQYQILSRYSNADNGEGDYVTYWFAPQSIAP ANQSNQGYLDSFDISKNGEVTVTGWNATDLSELQTNHYVILFDQTAGQQVASAKVDLISR PDVAKAYPTVKTAETSGFKVTFKVSNLQPGHQYSVVSRFSADENGNGNDKRHTDYWYSPV TLNQTASNIDTITMTSNGLHITGWMASDNSINEATPYAIILNNGREVTRQKLTLIARPDV AAVYPSLYNSAVSGFDTTIKLTNAQYQALNGQLQVLLRFSKAVDGNPNGTNTVTDQFSKN YATTGGNFDYVKVNGNQIEFSGWHATNQSNDKNSQWIIVLVNGKEVKRQLVNDTKDGAAG FNRNDVYKVNPAIENSIMSGFQGIITLPVTVKDENVQLVHRFSNDAKTGEGNYVDFWSEV MSVKDSFQKGNGPLNQFGLQTINGQQYYIDPTTGQPRKNFLLQNGNDWIYFDKDTGAGTN ALKLQFDKGTISADEQYRRGNEAYSYDDKSIENVNGYLTADTWYRPKQILKDGTTWTDSK ETDMRPILMVWWPNTVTQAYYLNYMKQYGNLLPASLPSFSTDADSAELNHYSELVQQNIE KRISETGSTDWLRTLMHEFVTKNSMWNKDSENVDYGGLQLQGGFLKYVNSDLTKYANSDW RLMNRTATNIDGKNYGGAEFLLANDIDNSNPVVQAEELNWLYYLMNFGTITGNNPEANFD GIRVDAVDNVDVDLLSIARDYFNAAYNMEQSDASANKHINILEDWGWDDPAYVNKIGNPQ LTMDDRLRNAIMDTLSGAPDKNQALNKLITQSLVNRANDNTENAVIPSYNFVRAHDSNAQ DQIRQAIQAATGKPYGEFNLDDEKKGMEAYINDQNSTNKKWNLYNMPSAYTILLTNKDSV PRVYYGDLYQDGGQYMEHKTRYFDTITNLLKTRVKYVAGGQTMSVDKNGILTNVRFGKGA MNATDTGTDETRTEGIGVVISNNTNLKLNDGESVVLHMGAAHKNQKYRAVILTTEDGVKN YTNDTDAPVAYTDANGDLHFTNTNLDGQQYTAVRGYANPDVTGYLAVWVPAGAADDQDAR TAPSDEAHTTKTAYRSNAALDSNVIYEGFSNFIYWPTTESERTNVRIAQNADLFKSWGIT TFELAPQYNSSKDGTFLDSIIDNGYAFTDRYDLGMSTPNKYGSDEDLRNALQALHKAGLQ AIADWVPDQIYNLPGKEAVTVTRSDDHGTTWEVSPIKNVVYITNTIGGGEYQKKYGGEFL DTLQKEYPQLFSQVYPVTQTTIDPSVKIKEWSAKYFNGTNILHRGAGYVLRSNDGKYYNL GTSTQQFLPSQLSVQDNEGYGFVKEGNNYHYYDENKQMVKDAFIQDSVGNWYYFDKNGNM VANQSPVEISSNGASGTYLFLNNGTSFRSGLVKTDAGTYYYDGDGRMVRNQTVSDGAMTY VLDENGKLVSESFDSSATEAHPLKPGDLNGQK > DME ID: DME1500 DME Name: Oligosaccharyltransferase (pglB) PDB ID: Not Available MEFQKHWLLMIQISVLFLSQKVCLHEIQELLNAKNMEKEKQEEVLNFQKDNQLPSFGLDF ISFSFRNLKNQLFIRLTSHSFFWHFVLLFIIFLLPLLFHYFDYLAFLKDSQNFFENTLIL TSYDSYFYAKGAKEFLETFNFNLPYLSVLGGILAKIFGLDNVLVWSSVFLSASFGVVLYF VIFEVLEYLAILTQKANQIFAFLGAFFGVLSPHFYQRNGVGYFDTDMLILSLPLLAIFCL WQYLIKRQFYFLFFFSIVAFLSVGWHSGIQNLLLAGFLLYVGYEIFNILVFKHTKSPILL ISSLFLIILTPSSYGFFVLLLALVVFYFEKSKISWVVFCIACVYAYFFGLFNPMIAQLKA YLFGEIQYSKTFIYASVVESILETSKANFTTLMQRSGGVGLFFLGLIGFVGFGFYYSLVR KNFIYLCIFLFPFLLLGFAALKLGVRFSFFLSPILALGCVLLVVGFLEIIRRFLKITLLI FAGILAIWVANLEYIIPKPILKAQEIEGLRALSFNSQDVAFVWWDYGYALEYFTQAQTLL HGGRHSGIVNYPIAEILLSHSAILAKNLSLLLAQKMQEIPKSQWNQIFEIVLKESNQTPQ NFLRQLTLDRFRLSDYPKGEVYWILPKKMLYLIANINGFRNVDLESGERIKEGIFLYEKT SLKTKEEDIFFKDFYLKKIQNGALAAKLIFEDRQFVMDFDYLQSNLIQWLVFKNNPVMNL VFENESVLIYQIPKE > DME ID: DME1501 DME Name: Oligosaccharyltransferase (pglB) PDB ID: Not Available MQNKNWLLIAVFVYLIAILLRFYYPFVLGEFEEYFYHNALLLNTNDGYFYAQGARDILAG VKSTFYSPTHEILSQISAFLALILPFSLEQIIFYMPGFFGSLIVFFVVFVSRDFGGIPSF LCGILSAISVSYYNRTMFGYYDTDMLVIVLAFGVGVVIVELMRKISFFGLVLLILLSGFG LVYYPSMRYIFVGYVGILTIFGIFDRNIRMVNGCLLSVLLGFLLFSTHFVFWLFLCFCGV MIKFIQRLDRRIFDFVYCLLLVIFCGILAFRVVPEIFASVYVAQDSKEIVGFGYASVMGT ISEVSKIDFWNFVYRISGNLLWFVLGSVGIILLFLKKREFWIFLPFLIMGFFGYFGGLRF TFYAVVVYALGIGYLLCFLLDIFKRKIKWAVIFGVVFVCGSVFPHLWHIKNYIIPPILEN SEAKALQEIPAKYGDYALAWWDYGYFVRYFARLNTFVDGGIHSGKQNYPISFVLSAKNQK QSYNMAKLTFNHIEFEDFAKSHQYSQSKALEALKGDIDCVGKRSEDLYIILPLRMVRIFS TIMQFSQPKGEINQGLLMVSKTKSKDKIIFQDNVFVDIKKGKVGILNQEISLNIAKMIDL KDSSKSLEFDKNSSLVVLMLGGGDYILCDKEYLETFYFRGMFLDNLDSNLFEKVLKNEKI AIYKLKQ > DME ID: DME1502 DME Name: Oligosaccharyltransferase (pglB) PDB ID: Not Available MLKSYSNFYILNKFSIHFLFITILCSIHFGFHYLDFKLLLDNPKNFISNTLILTSFDAYH YAKGTREFLEILNAPSVQRIFHALSTLPFLSLLGGILAKCTSLSFSLGFSSVIFSATLAP TLYALTYFNLNLLAQKRYFSKNSLAFIAFLASLIALFLPSFYQRVGAGYFDTDMLLLTLP LCALLFLLRFIQTQRFLSLVLFVLFGFLAINWHNGIQNLFLLGFLLFLCVEILCALRLHV ISKTHLMLASVFFVILTPSPFCLLTLIILLLAFRLYPKGIWFYFGIAIIYATTFGLFNPL IAQINAYIFGSTQHASNLVFASVVNAILETSPTTLSVLVARSGGILIFTLGILGFGILLY NAIFIFFKALISRQNPNKPLLYLSLFLLPFCFLGFFSLKLGVRFSFFLVPLIALGVALSL LFFYAKCYRYLQLCIFTSSIILPLSLITITYSIPKPILSAQEIQAFKVLDSKLSTNDFIF SWWDYGYALRYFTKAQVFLDGGRHSGAVNYPIAKILLSDSKELFYNFSMLLAQYLQNTDP KVWNRIFSLMLKNADSKEFLDSLTQGYKNISLAHNAQVYWVLPMRVLPLLANINLFANLN PENGKSLKNTSVFVFFDNTKLNFNTTINGTNTLLTQINLGQNSLLLSVDYLKSNIISLMI FQKLPQNVCASGDSVRIYHLKDSKCAESLVQ > DME ID: DME1512 DME Name: L-Lactate dehydrogenase (ldh) PDB ID: 1LLC; 2ZQY; 2ZQZ; 6J9S; 6J9T; 6J9U MASITDKDHQKVILVGDGAVGSSYAYAMVLQGIAQEIGIVDIFKDKTKGDAIDLSNALPF TSPKKIYSAEYSDAKDADLVVITAGAPQKPGETRLDLVNKNLKILKSIVDPIVDSGFNGI FLVAANPVDILTYATWKLSGFPKNRVVGSGTSLDTARFRQSIAEMVNVDARSVHAYIMGE HGDTEFPVWSHANIGGVTIAEWVKAHPEIKEDKLVKMFEDVRDAAYEIIKLKGATFYGIA TALARISKAILNDENAVLPLSVYMDGQYGLNDIYIGTPAVINRNGIQNILEIPLTDHEEE SMQKSASQLKKVLTDAFAKNDIETRQ > DME ID: DME1513 DME Name: Maltose phosphorylase (malP) PDB ID: Not Available MKRIFEVQPWNVITHTFDPKDKRLQESMTSLGNGYMGMRGDFEEGYSGDSLQGIYLGGVW YPDKTRVGWWKNGYPKYFGKVVNAVNFIKLPIEINGEPVDLAKDKISDFTLDLDMHQGVL NRSFVVERGAVRVALNFQRFLSVAQPELSVQKVTVKNLSDAEVDVTLKPSIDADVMNEEA NYDERFWDVLATDQQADRGSIVAKTTPNPFGTPRFTSGMEMRLVTDLKNVAITQPNEKEV TTAYTGKLAPQASAELEKRVIVVTSRDYDTQESLTAAMHQLSDKVAQSSYEDLLNAHTAI WAQRWEKSDVVIQGDDESQQGIRFNLFQLFSTYYGDDARLNIGPKGFTGEKYGGATYWDT EAFAFPVYLGITDPKVTRNLLMYRYKQLDGAYINAQEQGLKGALFPMVTFDGIECHNEWE ITFEEIHRNGDIAFAIYNYTRYTGDDSYVLHEGAKVLTEISRFWADRVHFSKRNNQYMIH GVTGADEYENNVDNNWDTNMLAQWTLKYTLEILGKVDQDTAKQLDVSDEEKTKWQDIVDR MYLPYDKDLNIFVQHDGFLDKDIEPVSSIPADQRPINQNWSWDKILRSPYIKQGDVLQGI WDFIDDYTPEQKKANFDFYEPLTVHESSLSPAIHSVLAADLHYEDKAVELYSRTARLDLD NYNNDTTDGLHITAMTGGWIAVVQGFAGMRVRDGQLHYAPFLPKTWTSYTFRQVFRDRLI EVSVHADGPHFKLLSGEPLTIDVAGEKVELTQNVTA > DME ID: DME1515 DME Name: Diol dehydratase (pddA) PDB ID: 1DIO; 1EEX; 1EGM; 1EGV; 1IWB; 1UC4; 1UC5; 3AUJ; 5YRT; 5YRV; 5YSH MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSDFD LIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHM NVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAP FNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPW SKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSV SCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFI SSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQ AVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQG GFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEE IKNIPGALDPNEID > DME ID: DME1520 DME Name: Homogentisate 1,2-dioxygenase (hmgA) PDB ID: Not Available MANPIDNAERRYQSGFGNEYASEAIAGALPQGRNSPQRAPFDLYTELLSGTAFTAPRHEN RRTWLYRRQPSVVSGRYQPYAQAHWTTGADREIALPPEPLRWHPLPLDGAAEVDFIDGMH TLAANGDAESQVGIGSLMYLAGRSMERRAFVNADGEMLIVPQQGRLVITTELGVLDVKPG EIALLPRGMAFKVALPDSDAGAGPSRGYVCENYGAQFRLPELGPIGSNGLANARDFQAPV AAFEEDGGAYELVKKFGGRFWKAPTKQSPFNVVAWHGNLAPVKYDTANFMVIGSISFDHP DPSIFTVLTSPSDTPGTANCDFVIFPPRWMVMENTFRPPWFHRNLMSEFMGLVLGEYDAK PGGFKPGGASLHNCMVPHGPDGEAFDKATHADLKPHKLDNTLAFMFESRYRFIPTNFALR SPALDTDYADCWAGLNDQFKA > DME ID: DME1524 DME Name: Cytochrome P450 101D1 (cyp101) PDB ID: 3LXH; 3LXI; 4C9K; 4C9L; 4C9M; 4C9N; 4C9O; 4C9P MNAQTSTATQKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTPF TGGHWIATRGTLIDEIYRSPERFSSRVIWVPREAGEAYDMVPTKLDPPEHTPYRKAIDKG LNLAEIRKLEDQIRTIAVEIIEGFADRGHCEFGSEFSTVFPVRVFLALAGLPVEDATKLG LLANEMTRPSGNTPEEQGRSLEAANKGFFEYVAPIIAARRGGSGTDLITRILNVEIDGKP MPDDRALGLVSLLLLGGLDTVVNFLGFMMIYLSRHPETVAEMRREPLKLQRGVEELFRRF AVVSDARYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSRRDVTHSTFAQ GPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWEPQRVS A > DME ID: DME1525 DME Name: Cytochrome P450 101D2 (cyp101) PDB ID: 3NV5; 3NV6; 4DXY MATNFDEAVRAKVERPANVPEDRVYEIDMYALNGIEDGYHEAWKKVQHPGIPDLIWTPFT GGHWIATNGDTVKEVYSDPTRFSSEVIFLPKEAGEKYQMVPTKMDPPEHTPYRKALDKGL NLAKIRKVEDKVREVASSLIDSFAARGECDFAAEYAELFPVHVFMALADLPLEDIPVLSE YARQMTRPEGNTPEEMATDLEAGNNGFYAYVDPIIRARVGGDGDDLITLMVNSEINGERI AHDKAQGLISLLLLGGLDTVVNFLSFFMIHLARHPELVAELRSDPLKLMRGAEEMFRRFP VVSEARMVAKDQEYKGVFLKRGDMILLPTALHGLDDAANPEPWKLDFSRRSISHSTFGGG PHRCAGMHLARMEVIVTLEEWLKRIPEFSFKEGETPIYHSGIVAAVENVPLVWPIAR > DME ID: DME1539 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MQEPNIKKRVSPWAWVSTLYFAEGLPNAAVVLVSLVFYQEMGLSDAEATFYTSWFYLPWV IKPLWSPFLDLIKTKRWWVLSMQMLLGAAFAGVAFTINTSFWLQGTICFFWLLAISSATH DVGADGFYMLGLESHEQAFFVGIRSTFYRISMVVGKGGLVALAGLLQEYMKVQLSWSLVF YGLSALFIGLSLYHKCILPKPITDVEHTQLSVSTLFKEFLDTFVSFFRKKEVFVAIAFML LFRLPEALLNTVGPLFLRATSEKGGLALSLEAFGVVNGVVGVVGLLLGGILGGLVASKGG LKKWLWPMTFAITLPNIAYVYLGYAMPSTLFAVGVAIFVENFGYGFGFSAYMLFMLYFSQ GEHKTSHYALCTGFMALSMMLPGLFAGALAEAVGYSLFFVLVMVACIFPFMVASLLKIDP KFGKKDI > DME ID: DME1542 DME Name: Sucrose-6-phosphate hydrolase scrB (ScrB) PDB ID: Not Available MFKKYNKVLKEDYEKWYAEHESDREETAKDPMRLKFHLMPKTGWLNDPNGLCQFHGTYHI YYQYTPFEPTGELKLWGHYTTKDFISYIDEGPVLFPDSEFDAHGVYSGSAFVKGDTIHYF YTGNIKCFDRDDYDYINSGRGSNTIHVASKDGYHFSEKDLLMTTDDYPEDMSCHVRDPKI IRRGDDYYMVQGARDIDSHGLILMFHSKDLSHWEYFDRIVPKEPFGYMWECPDLFELDGQ MMLITCPQGVEPKGIDYQNVHQCTAVKMDYDFENKSYEICDNSEFQQLDRGFDFYAPQTF EDEKGRRILIGWMGIPDADYTNPTVEHGWQHALTIPRELHIKDGRIIQRPIKEMEQMRKG ELICTFSEQGRMESNLKLYEAEVRFRHCADMVLTLKEGVTLSYDSGLLTLDLGDFGEGRT TRCAALDELKDLRIFADTTSLEIFVNGGEEVFTTRVYSSQGKLSIDGDCSGTMKIYCLRP LEIGERE > DME ID: DME1545 DME Name: Sucrose phosphorylase (Spase) PDB ID: Not Available MKNKVQLITYADRLGDGTLSSMTDILRTRFDGVYDGVHILPFFTPFDGADAGFDPIDHTK VDERLGSWDDVAELSKTHNIMVDAIVNHMSWESKQFQDVLEKGEESEYYPMFLTMSSVFP NGATEEDLAGIYRPRPGLPFTHYNLGGKTRLVWVSFTPQQVDIDTDSAKGWEYLMSIFDQ MAASHVRYIRLDAVGYGAKEAGTSCFMTPKTFKLISRLREEGVKRGLEILIEVHSYYKKQ VEIASKVDRVYDFALPPLLLHSLFTGHVEPVAHWTEIRPNNAVTVLDTHDGIGVIDIGSD QLDRSLKGLVPDEDVDNLVNTIHANTHGESQAATGAAASNLDLYQVNSTYYSALGCNDQH YLAARAVQFFLPGVPQVYYVGALAGRNDMELLRRTNNGRDINRHYYSTAEIDENLERPVV KALNALAKFRNELSAFDGEFSYEVDGDTSITFRWTAADGASTAALTFEPGRGLGTDNATP VASLAWSDAAGDHETHDLLANPPIADID > DME ID: DME1549 DME Name: Cytochrome P450 125A3 (cyp125) PDB ID: 4APY; 5DQN MPTPNIPSDFDFLDATLNLERLPVEELAELRKSEPIHWVDVPGGTGGFGDKGYWLVTKHA DVKEVSRRSDVFGSSPDGAIPVWPQDMTREAVDLQRAVLLNMDAPQHTRLRKIISRGFTP RAIGRLEDELRSRAQKIAQTAAAQGAGDFVEQVSCELPLQAIAELLGVPQDDRDKLFRWS NEMTAGEDPEYADVDPAMSSFELISYAMKMAEERAVNPTEDIVTKLIEADIDGEKLSDDE FGFFVVMLAVAGNETTRNSITHGMIAFAQNPDQWELYKKERPETAADEIVRWATPVSAFQ RTALEDVELGGVQIKKGQRVVMSYRSANFDEEVFEDPHTFNILRSPNPHVGFGGTGAHYC IGANLARMTINLIFNAIADNMPDLKPIGAPERLKSGWLNGIKHWQVDYTGAGKASVSGAP GTCPVAH > DME ID: DME1550 DME Name: Cytochrome P450 142A2 (cyp142) PDB ID: 2YOO; 3ZBY; 4TRI; 4UAX MTQMLTRPDVDLVNGMFYADGGAREAYRWMRANEPVFRDRNGLAAATTYQAVLDAERNPE LFSSTGGIRPDQPGMPYMIDMDDPQHLLRRKLVNAGFTRKRVMDKVDSIGRLCDTLIDAV CERGECDFVRDIAAPLPMAVIGDMLGVLPTERDMLLKWSDDLVCGLSSHVDEAAIQKLMD TFAAYTEFTKDVITKRRAEPTDDLFSVLVNSEVEGQRMSDDEIVFETLLILIGGDETTRH TLSGGTEQLLRHRDQWDALVADVDLLPGAIEEMLRWTSPVKNMCRTLTADTVFHGTELRA GEKIMLMFESANFDESVFGDPDNFRIDRNPNSHVAFGFGTHFCLGNQLARLELRLMTERV LRRLPDLRLADDAPVPLRPANFVSGPESMPVVFTPSAPVLA > DME ID: DME1551 DME Name: Cytochrome P450 125A1 (cyp125) PDB ID: 2X5L; 2X5W; 2XC3; 2XN8; 3IVY; 3IW0; 3IW1; 3IW2 MSWNHQSVEIAVRRTTVPSPNLPPGFDFTDPAIYAERLPVAEFAELRSAAPIWWNGQDPG KGGGFHDGGFWAITKLNDVKEISRHSDVFSSYENGVIPRFKNDIAREDIEVQRFVMLNMD APHHTRLRKIISRGFTPRAVGRLHDELQERAQKIAAEAAAAGSGDFVEQVSCELPLQAIA GLLGVPQEDRGKLFHWSNEMTGNEDPEYAHIDPKASSAELIGYAMKMAEEKAKNPADDIV TQLIQADIDGEKLSDDEFGFFVVMLAVAGNETTRNSITQGMMAFAEHPDQWELYKKVRPE TAADEIVRWATPVTAFQRTALRDYELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNIL RNPNPHVGFGGTGAHYCIGANLARMTINLIFNAVADHMPDLKPISAPERLRSGWLNGIKH WQVDYTGRCPVAH > DME ID: DME1552 DME Name: Cytochrome P450 142A1 (cyp142) PDB ID: 2XKR MTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFS NAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCER GECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFA AYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLS GGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEK MMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRR LPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG > DME ID: DME1553 DME Name: Tyrosine decarboxylase (tdc) PDB ID: 5HSI; 5HSJ MEKSNRSLKDLDLNALFIGDKAENGQLYKDLLNKLVDEHLGWRKNYIPSDPNMIGPEDQN SPAFKKTVGHMKTVLDQLSERIRTESVPWHSAGRYWGHMNSETLMPALLAYNYAMLWNGN NVAYESSPATSQMEEEVGQEFARLMGYDYGWGHIVADGSLANLEGLWYARNIKSLPFAMK EVNPELVAGKSDWELLNMPTKEIMDLLENAGSQIDEVKKRSARSGKNLQRLGKWLVPQTK HYSWMKAADIIGIGLDQVVPVPIDSNYRMDIQALESIIRKYAAEKTPILGVVGVAGSTEE GAVDGIDKIVALRQKLQKEGIYFYLHVDAAYGGYARALFLDEDDQFIPYKNLQKVHAENH VFTEDKEYIKPEVYAAYKAFDQAESITIDPHKMGYVPYSAGGIVIQDIRMRDTISYFATY VFEKGADIPALLGAYILEGSKAGATAASVWAAHHTLPLNVTGYGKLEGASIEGAHRYYDF LKNLKFEVAGKRISVHPLISPDFNMVDYVLKEDGNDDLIEMNRLNHAFYEQASYVKGSLY GKEYIVSHTDFAIPDYGDSPLAFVESLGFSEVEWRHAGKVTIIRASVMTPYMNQRENFDY FAPRIKKAIQADLEKVYASVNQKENV > DME ID: DME1559 DME Name: PenA beta-lactamase (penA1) PDB ID: Not Available MTHSSQRRILLLAAATAPLALSLGACAARDATVSDAASPVGAAPASFAALERAAGGRLGV CAIDTATGRRALHRADERFPFCSTFKAMLGAAVLAQSVAHPGLLQQRVTYGRSDLVNYSP VTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGPAAVTAYARSIGDDTFRLDRWET ELNTALPGDLRDTTTPAAMAANLRVLVLGDALPPAQRAQLIEWLRGNKVGDKRIRAGVPT GWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQTRADAKAKDDVIAAATRIASAT LA > DME ID: DME1561 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MESRLNTWRRTLFVFATGLLAAASASARPVCTVVADAATGQTLVRQGDCATRVTPASTFK VAISLMGFDAGFLKDEHTPTLDFHAGYPDWGGAPWREPTDPARWIKLSIFWYSEQVAQAL GPARFQQYTNAFGYGNTDVTGKQGELSGVMGAWVNSSLRISPLEQVAFMRKILHRTLPVS THAYDMTERITLIDAQPGGWTVHGKTGTGSPGLKYDAAHAYGWFVGWATKGPRTLVFANL IQDDKRQTPNAGLRSRDTFLAALPALAEPARPQ > DME ID: DME1562 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MTDSVLDVTADALEQAGAHPHRLVVRQHGQVVGRRRWAPWSPDVPSLVYSCSKTFTSAAV GIAVNRGAFGYDDTLADLWPQACTANTGPVAKSMTVRNALSMSTGHSPEQLLEPTLMSRR LPDLNTARILLATEPEGRPGIDFAYNNLATWMLSRLVAQHTGEDVDTIITKEVLDPIGAG PHTWVRDADGIPMGFSGLHIDAEDLSLFGQLLLDDGVHEGARLLPEEWIRQHRVRQVNCD SETDPEWGMGYGWQTWMSSHGYRLDGAFGQYVLIVPEVDAVITMTNEASEGPGDKQAILQ AVWDHLLPALADGFQPQPEEIVRTVPTVTGEFDSARSVQGIAPDGSYIVVSPHKESRTWA MSWRCPGTFSHPTDETLDIAVGYEEWQTSHCRVGDDAIDIATSGGWQGETFVARLCVIST PHTLTLRMTPEATTTEWDNEPLNPGGLLGLVHPELRR > DME ID: DME1563 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MLSRYSKTLAFAVVACTLAISTATAHAELVVRNDLKRVFDDAGVSGTFVLMDITADRTYV VDPARAARSIHPASTFKIPNSLIAFDTGAVRDDQEVLPYGGKPQPYEQWEHDMALPEAIR LSAVPIYQEVARRVGFERMQAYVDAFDYGNRQLGSAIDQFWLRGPLEISAFEEARFTSRM ALKQLPVKPRTWDMVQRMLLIEQQGDAALYAKTGVATEYQPEIGWWAGWVERAGHVYAFA LNIDMPREGDMAKRIPLGKQLMRALEVWPAP > DME ID: DME1564 DME Name: Beta-lactamase (blaB) PDB ID: Not Available EGTEGCFLLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDK TPKGMEIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNN GLTEAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTG AGFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL > DME ID: DME1566 DME Name: Mercaptosuccinate dioxygenase (efe) PDB ID: 5LSQ; 5LUN; 5MOF; 5V2T; 5V2U; 5V2V; 5V2X; 5V2Y; 5V2Z; 5V31; 5V32; 5V34; 5VKA; 5VKB; 6CBA; 6CF3 MTNLQTFELPTEVTGCAADISLGRALIQAWQKDGIFQIKTDSEQDRKTQEAMAASKQFCK EPLTFKSSCVSDLTYSGYVASGEEVTAGKPDFPEIFTVCKDLSVGDQRVKAGWPCHGPVP WPNNTYQKSMKTFMEELGLAGERLLKLTALGFELPINTFTDLTRDGWHHMRVLRFPPQTS TLSRGIGAHTDYGLLVIAAQDDVGGLYIRPPVEGEKRNRNWLPGESSAGMFEHDEPWTFV TPTPGVWTVFPGDILQFMTGGQLLSTPHKVKLNTRERFACAYFHEPNFEASAYPLFEPSA NERIHYGEHFTNMFMRCYPDRITTQRINKENRLAHLEDLKKYSDTRATGS > DME ID: DME1567 DME Name: Cytochrome P450 111A2 (cyp111) PDB ID: Not Available MSEETISQTVPPVREWPAIDLPGSDFDPVLTELMREGPVTRISLPNGEGWAWLVTRHDDV RLVTNDPRFGREAVMDRQVTRLAPHFIPARGAVGFLDPPDHTRLRRSVAAAFTARGVERV RERSRGMLDELVDAMLRAGPPADLTEALLSPFPIAVICELMGVPATDRHAMHTWTQLILS SSHGAEVSERAKNEMNAYFSDLIGLRSDSTGEDVTSLLGAAVGRGEITLTEAVGLAVLLQ IGGEAVTNNSGQMFHLLLSRPELAERLRSDPALRPRAIDELLRWIPHRNAVGLSRIALED VEVKGARIRAGDAVYVSYLAANRDPEVFPDPDTIDFDRSPNPHVSFGFGPHYCPGGMLAR LESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPEALPVTW > DME ID: DME1584 DME Name: Retro-nitroreductase (rNR) PDB ID: Not Available MDIISVALKRHSTKAFDPAKKLTADEAEKIKTLLQYSPSSTNSQPWHFIVASTEEGKARV AKSAAGTYVFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEEADGRFNTPEAKAANHKG RTYFADMHRVDLKDDDQWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDEEFGLKE KGFTSLVVVPVGHHSVEDFNATLPKSRLPLSTIVTEC > DME ID: DME1586 DME Name: Oxygen-insensitive NADPH nitroreductase A (nfsA) PDB ID: Not Available MSLQDEALKAWQARYGEPANLPAADTVIAQMLQHRSVRAYSDLPVDEQMLSWAIAAAQSA STSSNLQAWSVLAVRDRERLARLARLSGNQRHVEQAPLFLVWLVDWSRLRRLARTLQAPT AGIDYLESYTVGVVDAALAAQNAALAFEAQGLGIVYIGGMRNHPEAMSEELGLPNDTFAV FGMCVGHPDPAQPAEIKPRLAQSVVLHRERYEATEAEAVSVAAYDRRMSDFQHRQQRENR SWSSQAVERVKGADSLSGRHRLRDALNTLGFGLR > DME ID: DME1615 DME Name: Naphthalene dioxygenase (doxB) PDB ID: 2HMJ; 2HMK; 2HML; 2HMM; 2HMN; 2HMO; 4HJL; 4HKV; 4HM0; 4HM1; 4HM2; 4HM3; 4HM4; 4HM5; 4HM6 MNYNNKILVSESGLSQKHLIHGDEELFQHELKTIFARNWLFLTHDSLIPAPGDYVTAKMG IDEVIVSRQNDGSIRAFLNVCRHRGKTLVSVEAGNAKGFVCSYHGWGFGSNGELQSVPFE KDLYGESLNKKCLGLKEVARVESFHGFIYGCFDQEAPPLMDYLGDAAWYLEPMFKHSGGL ELVGPPGKVVIKANWKAPAENFVGDAYHVGWTHASSLRSGESIFSSLAGNAALPPEGAGL QMTSKYGSGMGVLWDGYSGVHSADLVPELMAFGGAKQERLNKEIGDVRARIYRSHLNCTV FPNNSMLTCSGVFKVWNPIDANTTEVWTYAIVEKDMPEDLKRRLADSVQRTFGPAGFWES DDNDNMETASQNGKKYQSRDSDLLSNLGFGEDVYGDAVYPGVVGKSAIGETSYRGFYRAY QAHVSSSNWAEFEHASSTWHTELTKTTDR > DME ID: DME1617 DME Name: Oxygen-insensitive NADPH nitroreductase B (nfsB) PDB ID: 3HZN MDIVSVALQRYSTKAFDPSKKLTAEEADKIKTLLQYSPSSTNSQPWHFIVASTEEGKARV AKSAAGNYTFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEDADGRFATPEAKAANDKG RRFFADMHRVSLKDDHQWMAKQVYLNVGNFLLGVAAMGLDAVPIEGFDAEVLDAEFGLKE KGYTSLVVVPVGHHSVEDFNAGLPKSRLPLETTLTEV > DME ID: DME1623 DME Name: VanB ligase (vanB) PDB ID: Not Available MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGITKNGVWKLCKKPCTEWE ADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCGEDGAIQGLFVLSGIPYVG CDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEAGALTYPVFVKPARSGSSFGV TKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAVMGNEDDLIVGEVDQIRLSHGIF RIHQENEPEKGSENAMITVPADIPVEERNRVQETAKKVYRVLGCRGLARVDLFLQEDGGI VLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDSLITLALKR > DME ID: DME1630 DME Name: VanA ligase (vanA) PDB ID: Not Available MMKKIAVLFGGNSPEYSVSLASAASVIQAIDPLKYEVMTIGIAPTMDWYLYQGNLKNVRN DTWLEDHKNCHQLTFSSQGFMLGEKRIVPDVLFPVLHGKYGEDGCIQGLLELMNLPYVGC HVAASALCMNKWLLHQLADTMGIASAPTLLLSRYENDPATIDRFIQDHGFPIFIKPNEAG SSKGITKVTDKTALQSALTNAFAYGSTVLIQKAIAGIEIGCGILGNEQLTIGACDAISLV DGFFDFEEKYQLISATITVPAPLPLALESQIKEQAQLLYRNLGLTGLARIDFFVTDQGAI YLNEINTMPGFTGHSRYPAMMAEVGLSYEMLVEQLIALAEEDKR > DME ID: DME1631 DME Name: VanA ligase (vanA) PDB ID: Not Available MKKIAIIFGGNSPEYTVSLASATSAIEALQSSPYDYDLSLIGIAPDAMDWYLYTGELENI RQDTWLLDTKHTQKIQPLFEGNGFWISEAQQTLVPDVLFPIMHGKYGEDGSIQGLFELMK LPYVGCGVAASALCMNKWLLHQAAAAIGVQSAPTILLTNQANQQRQIEAFIQTHGFPVFF KPNEAGSSKGITKVTCVEEIAPALKEAFAYCSAVLLQKNIAGVEIGCGILGNDSLTVGAC DAISLVDGFFDFEEKYQLISAKITVPAPLPETIETKVKEQAQLLYHSLGLKGLARIDFFV TDQGELYLNEINTMPGFTSHSRYPAMMAAVGLSYQELLQKLLVLAKEEGK > DME ID: DME1632 DME Name: Aminoglycoside adenylyltransferase (aadA1a) PDB ID: Not Available MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDIDLLVTVTVRLDE TTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAKRELQFGEWQRNDILAG IFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQDLFEALNETLTLWNSPPDWA GDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPAQYQPVILEARQAYLGQEEDRLA SRADQLEEFVHYVKGEITKVVGK > DME ID: DME1636 DME Name: L-fucose isomerase (fucI) PDB ID: Not Available MKRISLPKIGIRPVIDGRRMGVRESLEAQTMNMAKATAALISEKLRHACGAQIECVIADT CIAGMAESAACEEKFSRQNVGVTITVTPCWCYGSETIDMDPLRPKAIWGFNGTERPGAVY LAAALAAHSQKGIPAFSIYGHDVQDADDTTIPADVEEKLLRFARAGLAVASMKGKSYLSV GGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEVELEMALAWADKNFRY GEDQNAQHYKRDEEQSRAVLKESLLMAMCIRDMMQGNEKLAEKGLLEESLGYNAIAAGFQ GQRHWTDQYPNGDTAEALLNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFA DVRTYWSPDAVERVTGQPLTGLAEHGIIHLINSGSAALDGSCQQRDEEGKPTMKPHWEIS QKEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNLIKGLGPVLQIAEGWS VELPKAMHDQLDARTNSTWPTTWFAPRLTGKGPFADVYSVMANWGANHGVLTIGHVGADF ITLAAMLRIPVCMHNVEEGKIYRPSSWSAHGMDTEGQDYRACQNYGPLYKR > DME ID: DME1637 DME Name: Beta-galactosidase (bgaB) PDB ID: Not Available MSKKLPEDFIFGGATAAYQAEGAIKIDGKGPVAWDKFLEENYWYTAEPASDFYHQYPVDL KLCEEFGINGIRISIAWSRIFPNGYGEVNPKGVEFYHKLFAECKKRKVEPFVTLHHFDTP EVLHSNGDFLNRENIEHFVNYAKFCFEEFSEVNYWTTFNEIGPIGDGQYLVGKFPPGIKY DFEKLFQSHHNMVLAHAKAVNLFKKNGYHGEIGMVCALPTKYPYDPNNPKDVRAAELDDI IHNKFILDATFKGEYSKNTMEGVNHILQVNGGKLDLREEDFEELKAAKDLNDFLGINYYM SDWMAEYDGETEIIHNATGNKGSSKYQIKGVGQRKANESIPRTDWDWIIYPQGLYDQISR VKKDYPNYKKIYITENGLGYKDVFEDNTVYDDARIDYIRQHLEVISDAIKDGANVKGYFL WSLMDVFSWSNGYEKRYGLFYVDFETQKRYPKKSAYWYKKVSETKEV > DME ID: DME1641 DME Name: Endoglucanase Y (EGY) PDB ID: Not Available MKKYQPTDLIKFASRTGRWTIKKLDNSPTLYTTNLGSYLRFKVSDAKKCQITVLPNQNSL SPSQVFAFRIDGGKWQRAQASLEKIDIPLDSTLHTIEIMAAGNTDIDEVWQGNEGFAIKN IYLDRGEITAAPQRPLINFIGDSITAGCWVVGNHPAADYRPETNYAGICADLLNVDSVRI AYSAGGVLRPATGGVPTADVFLGKIDNQTLWTPNHPDLNVINLGVNDRRFPLTQFIAAFD LFIQQVKLTFPHTPLAIIIPFSQTFASAIRTIATKHDCSIIETKTWHHSFTDGLHPDQAG AINEGKMLAQALQPLLPQFSVQ > DME ID: DME1642 DME Name: Endoglucanase Y (EGY) PDB ID: Not Available MKKYQPTDLIKFASRTGRWTIKKLDNSPTLYTTNLGSYLRFKVSDAKKCQITVLPNQNSL SPSQVFAFRIDGGKWQRAQASLEKIDIPLDSTLHTIEIMAAGNTDIDEVWQGNEGFAIKN IYLDRGEITAAPQRPLINFIGDSITAGCWVVGNHPAADYRPETNYAGICADLLNVDSVRI AYSAGGVLRPATGGVPTADVFLGKIDNQTLWTPNHPDLNVINLGVNDRRFPLTQFIAAFD LFIQQVKLTFPHTPLAIIIPFSQTFASAIRTIATKHDCSIIETKTWHHSFTDGLHPDQAG AINEGKMLAQALQPLLPQFSVQ > DME ID: DME1643 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MMQSLKFRTLAGMLGCLTFLPLAAQAANDAGKSDLDAAVEATIPPLMKAKDIPGMAVAVL ADGKAHYFNYGVASRETGQPVTQDTLFELGSISKTFTGILGGYALAQGKLSLADKASRYQ PELKGSVFDRVSLLQLATYSAGGLPLQFPDAVAGQASMLAYYRGWKPDYAPGERRLYSNP SIGLFGHLAARSLGQPFDQAMERGLLPKLGLSHTFIHVPEAEQSRYAWGYAKAGKPIRVG AGVLDAEAYGIKSSAADLLKYLAINMSPPADPALQRALDASHAAYYRVGDMRQGLGWEGY RYPISLERLLAGNSNEIAFQPQKVEWLNPPRLAEGDVLLNKTGSTSGFGAYVLFVPARKV GIVMLANRNYPNAERVRAAYRILLAVDPSLARRRGD > DME ID: DME1662 DME Name: Cytochrome P450 121A1 (cyp121) PDB ID: 1N40; 1N4G; 2IJ5; 2IJ7; 3CXV; 3CXX; 3CXY; 3CXZ; 3CY0; 3CY1; 3G5F; 3G5H; 4G1X; 4G2G; 4G44; 4G48; 4ICT; 4IPS; 4IPW; 4IQ7; 4IQ9; 5IBD; 5IBE; 5IBF; 5IBG; 5IBH; 5IBI; 5IBJ; 5OP9 MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRF SMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSL LDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKI NWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGS FLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVR KGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIE ALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW > DME ID: DME1664 DME Name: Cytochrome P450 monooxygenase 51A (cyp51A) PDB ID: Not Available MVPMLWLTAYMAVAVLTAILLNVVYQLFFRLWNRTEPPMVFHWVPYLGSTISYGIDPYKF FFACREKYGDIFTFILLGQKTTVYLGVQGNEFILNGKLKDVNAEEVYSPLTTPVFGSDVV YDCPNSKLMEQKKFIKYGLTQSALESHVPLIEKEVLDYLRDSPNFQGSSGRVDISAAMAE ITIFTAARALQGQEVRSKLTAEFADLYHDLDKGFTPINFMLPWAPLPHNKKRDAAHARMR SIYVDIITQRRLDGEKDSQKSDMIWNLMNCTYKNGQQVPDKEIAHMMITLLMAGQHSSSS ISAWIMLRLASQPKVLEELYQEQLANLGPAGPDGSLPPLQYKDLDKLPFHQHVIRETLRI HSSIHSIMRKVKSPLPVPGTPYMIPPGRVLLASPGVTALSDEHFPNAGCWDPHRWENQAT KEQENDKVVDYGYGAVSKGTSSPYLPFGAGRHRCIGEKFAYVNLGVILATIVRHLRLFNV DGKKGVPETDYSSLFSGPMKPSIIGWEKRSKNTSK > DME ID: DME1674 DME Name: Arylsulfate sulfotransferase (astA) PDB ID: Not Available MSVKYSFEDHIVNRQYEAEQEMLKEFEAGNYTIANPLVKYNAYLVNPLSAVVCFHTEKET AITVTVLGKTPQGNISHTFPKAKKHVLPIVGLYSDYQNRVEIRAYRGESNIITIDVPDVF DGKEVIYSMDTTPEYLQDNIILVSPAGEDLAVGFDYAGDARWHMTIPCVFDVKRLKNGNL IMGSHRVIQMPYYMSGLYEISPCGKIYKEFRLPGGYHHDEFEMEDGNLLSLTDDLTSETV EDMCVLIDRNTGEILKTWDYKKFLDPKKVSKSGSWSDHDWFHNNAVWYDKNTNSLTFSGR HIDSMVNIDYETGELNWIIGDPEGWPEEMQKYFFKPVGNNFGWQYEQHACVITPDGDVMC FDNHHYGSKNPEKYLAARDNYSRGVRYKINTDDMTIEQVWQYGKDRGAEFFSPYICNVEY YNEGHYMVHSGGIAYDTEGNPSEALGAFAKDQGGRLESITVEICDNKKMLDLHVPGNYYR GEKLKLYSDGINLELGKGQILGEMGVTKEFDTEIPLEPSGEMLPESCNARIEDEIDRFTF FSRFEKGQLVMLLLEQGEEVHRYFISTTAVPFLAMCCGTFLDSDDRNTRTNINKTGLKGT YDLRVIIDDKKYETGVTISC > DME ID: DME1677 DME Name: Beta-glycosidase (glyB) PDB ID: Not Available MRTFSKKKKLPRLLTLCGAVAVSALLGGCGQSGVPAESFDRSDYYTRGIGSYPGDPGEDF SPSLRPDYSTYRNIALLRSAYNSSSYDYNLTAQLVTDGVISDKQPQYLDLSTQNGDIARR EREWMIDQGPYSRNAVTGEDAYFLFTLNNWKEKADKVQFRGSVAYDENKIKDGYEIVCEG SNDGNTWTELAALKGKGMPGKASKYKAHSDPNKNSWDPGTLPTRMLNETLTFDQPGEYAY YRMRLKMEGAAYWAFFEMNFYNQDKLIDLLPSKFFNSAWMSATTGEEWVYVDLGSQSEFD KVKLHWINKAIKGKIQVSDDAKQWVDIANLPGGDANLDEIKLKGKGRYVRVWMEQPANDG RYILSEIEVMGKGGLLAQPAAAPAATKDEIRLSGGNWKVQRASEVTASGEEISKPSFSPE NWIVATVPGTVLSSYKNIGAIPNPNYADNLMQISESFFNSNFWYRDEFEVPEGFKQDRLF LNFDGINWKANVYLNGNKIGRIEGAFIRGVFDVTDRVVPGKNVVAVEIIKNEHIGAIKEK CEKNTDFNGGILGADNPTFHASIGWDWISTIRGRNIGIWDDVYLTSTGKVTIQDPFVQVV LPLPDTTSATLTPEVIVKNHDAAPVKGVLTGKIGDITFEQPVELAANEEKTVTFDPNSFS QLKVQNPRLWWPKGYGSPYLYDANFTFKVGDKVSDSEDFKVGIRQMTFNENNSILSLFIN GRRFIGRGGNWGFGESNLNYRGREYDIAVAYHADMNFTMMRNWVGQIGDKELYEACDRHG IMIWQDFWLANPSDGPDPYDPEMFIANAEDYVKRFRNHASIGIYCGRNEGFPPEQIDKAL RRIVKEDHPGLHYISSSADEVVSGHGPYRALPVKEYFSLKNGSDKFHSERGMPNVMNYES LVRTFSPEALWPQNAQWGQHDYTMEGAQSCASFNAIIEKGFGKPNNAKEFADLAQWVNYD GYRGMFESRSLNRKGLLLWMTHPAWPSMVWQTYDYYFEPTAAYFGCKKASEPLHIQWNPV TDEIEVVNYSAGVRNGLTAKAQIINMDGSISWENEVSVDSKEDTTNKCMKLDFPASVSSA HFVKLTLTENGKIVSDNFYLRGVEEGNYQALREMPKVTLRSNVATNKGNDGTWTATATLE NTSSTPALMIRVNVIGEKDGQQFLPMFYSDNYFSLLPGEKKEINIHWKDVDTRGEAPKVV ISGYNVN > DME ID: DME1678 DME Name: GH3 beta-glucosidase (BAD1610) PDB ID: Not Available MTMPRSMYNHADKQEDKEKSYIELDSTETEIIKYLNDNYKDVILLVKSSAAMELDWLKQY PNIKAVVYSQNVTNALAKVFSGEVNPSGRTVDTFAADALASPAAQNFGSYQYYDENGKAT KYNYVDYAEGIYVGYKYYETRYEDKVLGQGNAGDYDYAKEVVYPFGYGLSYTDFKWSDFS VARHGNDFVATVTVTNTGDTAGKDVVELYAQSPYTDYDKRNAVEKASVNLVGYGKTSELK PGTSETVRITFGKDQLKAYDYKGAKTYILDAGQYRFTAATDANQAVNNILADKGKTVADG MTSEGDKTMVASWTPENTDADTTTFASDSTTGKAISNLFDAASDPEVAYLSRSDWTGTFP KHYGESSGEINTWGNEINCKDSDGNNASCTWKKTASTKLIKHLEGNDSGTTVDKDSIMDT PTFGKKNGLKVSDMRGLAYDDAQWDKILDELTEDDYNQLIYFSGYGVDYIKSVDKPFQTD ADSATGWMYGGTGKTFPSIMMLTQTWNAQLAEDLGEMMGNEALLGGANGWYAPAMNIHRT PFSGRNGEYYSEDGYMSGSMASLEVKGAATKGVYSYIKHFALNDQENHRGDRPGNFSVAT WSNEQAIREIYLKPFDMCMHLGDMDMKTVVKKSDGTYENKVVKTPIAKGVMTSFNRIGAT WTGGSHALIQQLLRDEWGFNGLIITDNANTGKFMSPYQMLEAGADIKLLNVSDDPTGEKL DFNDAATYHYARQAMHHLLYTVANTNCMNGALPGAGFKFSNGMKTIQIVFNTVCSVILAM LAFFSVWRWMPGTIKRVAARKEARVARKAARKAAKG > DME ID: DME1686 DME Name: D-Lactate dehydrogenase (ldhA) PDB ID: 3WWY; 5Z21; 6ABI MQKTKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLTKGYDVVCGFANDNIN KETIDIMAENGIKLLAMRCAGFNNVSLKDVNERFKVVRVPAYSPHAIAEYTVGLILAVNR KINKAYVRTREGNFSINGLMGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIAYDLFPN QKVADELGFEYVSLDELYANSDIISLNCPLTKDTKYMINRRSMLKMKDGVILVNTGRGML IDSADLVEALKDKKIGAVALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVLITSHQA YFTKEAVGAITVTTLNNIKDFVEGRPLVNEVPQNQ > DME ID: DME1687 DME Name: D-Lactate dehydrogenase (ldhA) PDB ID: 1DLD; 1J49; 1J4A MTKIFAYAIREDEKPFLKEWEDAHKDVEVEYTDKLLTPETVALAKGADGVVVYQQLDYTA ETLQALADNGITKMSLRNVGVDNIDMAKAKELGFQITNVPVYSPNAIAEHAAIQAARILR QDKAMDEKVARHDLRWAPTIGREVRDQVVGVIGTGHIGQVFMQIMEGFGAKVIAYDIFRN PELEKKGYYVDSLDDLYKQADVISLHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLV DTDAVIRGLDSGKIFGYAMDVYEGEVGIFNEDWEGKEFPDARLADLIARPNVLVTPHTAF YTTHAVRNMVVKAFDNNLELVEGKEAETPVKVG > DME ID: DME1688 DME Name: L-Lactate dehydrogenase (ldh) PDB ID: Not Available MSRKVLLVGDGAVGSNFANDLLQTTQVDELVICDLNKDRAAGDCLDLEDMTYFTGQTKLR AGDYSDAADADVVVITAGVPRKPGESRLDLIKKNEAILRSIVDPVVASGFSGIFVVSANP VDILTTLTQKLSGFPKKRVIGTGTSLDSARLRVELAKRLQVPIESVNAWVLGEHGDSSFE NFSSAVVNGKPLLDYPGMTEAALDEIEAHVREKGSEIIVKKGATYYGVAMMLAKIVTAIL ENNDLALPLSAPLHGEYGIKDEIYLGTLAIINGQGISHVLELPLNDSELAKMRASAATIK ATLDSLG > DME ID: DME1690 DME Name: D-Lactate dehydrogenase (ldhA) PDB ID: 5Z1Z MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANGCEAVCIFVNDDGSRPV LEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRI HRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAA ALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDS QAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLT AEALTSISQTTLQNLSNLEKGETCPNELV > DME ID: DME1691 DME Name: Pyruvate oxidase (pyrO) PDB ID: Not Available MATKAADQLVSVLMDWQVKHVFGLPGDSIDTTVDALRRHQDKIKFVQVRHEEVAALAASA TAKLTGGLGVCLSIGGPGAIHLLNGLYDAKMDHAPVLALLGQVTTSNLNEGFFQEVNTPK LFDDVAVYNKTVMASDNLGQIVDTAIRTAFTEKGVAVLTIPDDLPDQKETTSYRDSAAAF ALNVPEVDPKQLDDVASLLQKSQKPLALIGRGAEHAGEQVQKFVEANHIPFIQTMPAKGT VADDHPNSLGNVGKLGTKPAYEAMKATDLLFMIGTNYPYTPYLPDEGQAKCVQIDTQPEN LGKRYSVDVAVDGDVETFLTELNAKGSLRDDDRFLKACQKNMESWDKWMAEKRLLTTNPA SPEAVFATIDQTAPKDAVYSVDVGTSTSWGARFLNVQPTQKYTISAWLGTMGCGLPGAIA GAEAFPKRQNISVAGDGAFAMVMQDFVTAVKYKLPIIMVVLNNQKLAFIEYEQQSAGQLN YEIDLADMDYAKIAEAAGGVGYTAHSNDEFKEALTKAYQETEKPVLINTYVQDDAPLPGK IVGEEAKGYMKYGSQYLENYWKIPSMPPLKDIMRQFF > DME ID: DME1693 DME Name: D-Lactate dehydrogenase (ldhA) PDB ID: Not Available MRILFFSSQAYDSESFQASNHRHGFELHFQQAHLQADTAVLAQGFEVVCAFVNDDLSRPV LERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEHAVGLILTLNRRL HRAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFARIMTGFGCELLAYDPYPNPR IQALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNA AALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVTAHQAFLT REALAAIADTTLDNIAAWQDGTPRNRVRA > DME ID: DME1694 DME Name: Xylose isomerase (xylA) PDB ID: Not Available MAKQYFPTVGKIAFEGTSSKNPMAFRYYEPERVVKGRKMKDWLRFSMAWWHTLCAEGADQ FGGGTKQFAWNEAACPIERAKAKMDAGFEFMQKMGIEYYCFHDVDLVDEDPDPVKYEQNL REIVAYAKQKQAETGIKLLWGTANVFGNARYMNGASTNPDFDTAARAMLQIKNAIDATIE LGGENYVFWGGREGYMSLLNTDMKREKEHMATMLTMARDYARSKGFKGNFLIEPKPMEPM KHQYDVDTETVIGFLRAHGLDKDFKVNIEVNHATLAGHTFEHELQCAVDAGMLGSIDANR GDYQNGWDTDQFPIDLYEMVQAMMVIVRGGGLQGGGTNFDAKTRRNSTDPEDLFIAHIAA MDVMARALLIAADLLDNSPYQKMLAERYASYDKGEGKAFEEGKLTLEQVADYARTHEPVQ HSGKQELYEAILNMYM > DME ID: DME1699 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKSLSATLISALLAFSAPGFSAADNVAAVVDSTIKPLMAQQDIPGMAVAVSVKGKPYYF NYGFADVQAKQPVTENTLFELGSVSKTFTGVLGAVSVAKKEMTLNDPAEKYQPELALPQW KGITLLDLATYTAGGLPLQVPDAVKSRADLLHFYQQWQPSRKPGDMRLYANSSIGLFGAL TANAAGMPYEQLLTARILAPLGLSHTFITVPESAQSQYAYGYKNKKPVRVSPGQLDAESY GVKSASKDMLRWAEMNMEPSRAGNADLEMAMYLAQTRYYKTAAINQGLGWEMYDWPQQKD MIINGVTNEVALQPHPVTDNQVQPYNRASWVHKTGATTGFGAYVAFIPEKQVAIVILANK NYPNTERVKAAQAILSALE > DME ID: DME1711 DME Name: Beta-fructofuranosidase (BFRU) PDB ID: Not Available MEWTRESRYKKYSEWDAETLLKLQAQATASKYQMSYHIRPQSGLLNDPNGFSYFNDEYHV FYQSYPFGAVHGLKSWVHLTSPDLVHWKNLGLAINADTKYDSHGAYSGSARVIDDKLFLM YTGNHRSKEWVRYPYQIGAIMDKDNNITKLDKPMIEPVDHITEHFRDPQLLKHRDEYFVI LGAQDAETKTGKISLFRSKDLKNWQDLGYLDFTEEEMGYMVECPNLVFIDDQPVLIFCPQ GLDKKVADYENIYPNMYIVGSNIRLDKAKFNTDQKAPLNLDDGFDVYATQAFTAPNGKAY AISWIGLPDISYPTDSENWANCLSQVKELSVVDGELYQRPVPAMASLREEGTLVRSEEVF DGQQIVHSAASKHYELKLDLTAGQNGKLFLAANKDLSQGIEIKFSTADDAFLTVDRSKAG IPFAEDYGTTRNIALPANKQLSLDIFVDGSVCEIFVNNGRHTLTLRFFAPDGNDKIAFIS DKKLQYTGTYWNMKNI > DME ID: DME1712 DME Name: Beta-fructofuranosidase (BFRU) PDB ID: Not Available MEWTRESRYKKYSEWDAETLLKLQAQATASKYQMSYHIRPQSGLLNDPNGFSYFNDEYHV FYQSYPFGAVHGLKSWVHLTSPDLVHWKNLGLAINADTKYDSHGAYSGSARVIDDKLFLM YTGNHRSKEWVRYPYQIGAIMDKDNNITKLDKPMIEPVDHITEHFRDPQLLKHRDEYFVI LGAQDAETKTGKISLFRSKDLKNWQDLGYLDFTEEEMGYMVECPNLVFIDDQPVLIFCPQ GLDKKVADYENIYPNMYIVGSNIRLDKAKFNTDQKAPLNLDDGFDVYATQAFTAPNGKAY AISWIGLPDISYPTDSENWANCLSQVKELSVVDGELYQRPVPAMASLREEGTLVRSEEVF DGQQIVHSAASKHYELKLDLTAGQNGKLFLAANKDLSQGIEIKFSTADDAFLTVDRSKAG IPFAEDYGTTRNIALPANKQLSLDIFVDGSVCEIFVNNGRHTLTLRFFAPDGNDKIAFIS DKKLQYTGTYWNMKNI > DME ID: DME1713 DME Name: Beta-fructofuranosidase (BFRU) PDB ID: Not Available MEWTRESRYKKYSEWDAETLLKLQAQATASKYQMSYHIRPQSGLLNDPNGFSYFNDEYHV FYQSYPFGAVHGLKSWVHLTSPDLVHWKNLGLAINADTKYDSHGAYSGSARVIDDKLFLM YTGNHRSKEWVRYPYQIGAIMDKDNNITKLDKPMIEPVDHITEHFRDPQLLKHRDEYFVI LGAQDAETKTGKISLFRSKDLKNWQDLGYLDFTEEEMGYMVECPNLVFIDDQPVLIFCPQ GLDKKVADYENIYPNMYIVGSNIRLDKAKFNTDQKAPLNLDDGFDVYATQAFTAPNGKAY AISWIGLPDISYPTDSENWANCLSQVKELSVVDGELYQRPVPAMASLREEGTLVRSEEVF DGQQIVHSAASKHYELKLDLTAGQNGKLFLAANKDLSQGIEIKFSTADDAFLTVDRSKAG IPFAEDYGTTRNIALPANKQLSLDIFVDGSVCEIFVNNGRHTLTLRFFAPDGNDKIAFIS DKKLQYTGTYWNMKNI > DME ID: DME1714 DME Name: Alpha-galactosidase (melA) PDB ID: 2XN0; 2XN1; 2XN2 MTSNLIKFDDQNKVFHLHNKQISYLLSIEDGGTLSHLYFGGAVKNYNNQLKYPRLDRGFS GNLPESLDRTFSRDSLPKEYSSAGEMDFHTPATIVRNPDGSNALFLAYKSYKIEDGKPDL KGLPHSWTKEDDEAQTLIVTLEDKVSKLEYDLLYTIYRDRPVIVRSVQVHNHGEEAVYLE KVASMQMDYVDKDFEVITLPGAHANERRVQRENIGQGIKVFSSYRGTSSHQMNPFMALVD HDTNEFMGEAYGFALAYSGNHKFEVERDQFGQIHVNTGINDYNFKWKLNPNEEFQTPEVL MVYSDQGLNKMSQAFHSLIHERIMRSKFKDQIRPVLVNNWEATYFDFNEDKLKTIVDKAK KLGLEMFVLDDGWFGHRDDDNSSLGDWKVYKKKFPNGLGHFADYVHEQGLKFGLWFEPEM ISYESNLYKEHPDYLMHVPGRKPCPSRNQYVLELGRKEVRDNIFEQMVKILDSKKIDYIK WDMNRSLSDIYESDLPADQQGEAYHRYVLGYYDLLNKLVTRYPDILFEGCSGGGGRFDVG QAYYTPQIWASDNTDAIERLKIQYGTSLVYPQSMMTSHVSVSPNEQNGRITPFNTRGAVA MWGDLGYELDLTKMSDEESDQVVKQVTEYKKIREVTQFGTLYRLKASASNQCAWMMVDSN KNEAVVTVVNVMAHAQPYCTKTKLAGLDPDKRYKNLETDEVFGGDELMHLGFYDPIERGD FKAKMYHFKAIN > DME ID: DME1715 DME Name: Beta-galactosidase (bgaB) PDB ID: Not Available MTQLSRFLYGGDYNPDQWPEETWSKDIHVFKKADINSATINIFSWALLEPREGKYNFSKL DKVVQQLSDANFDIVMGTATAAMPAWMFKKYPDIARVDYQDRRHVFGQRHNFCPNSSNYQ RLAGELEKQLVERYKDNKHIVFWHINNEYGGNCYCENCQNAFKKWLKNKYKTVEGLNKAW NMNVWSHTIYDWDEIVVPNELGDVWGIKGSETIVAGLSIDYLRFQSESMQNLFKMEKKII KKFDPETPVTTNFHGLPNKMVDYQKWAKGQDIISYDSYPTYDAPAYKAAFLYDLMRSLKH QPFMLMESAPSQVNWQPYSPLKRPGQMEATEFQAVAHGADTVQFFRLKQAVGGSEKFHSA VIAHSQRTVTRVFKELADLGKKLKNAGPTILGSKTKARFAIVFDWSNFWSYEYVDGITQD LNYVDSILDYYRQFYERNIPTDIIGVDDDFSNYDLVVAPVLYMVKHGLDKKINDYVENGG NFVTTYMSGMVNSSDNVYLGGYPGPLKEVTGIWVEESDAVVPGQKIKVLMNGKDYDTGLI CNLIHPNDAKILATYASEFYAGTPAVTENQYGKGRAWYIGTRLEHQGLTQLFNHIIFETG VESLVCDSHKLEITKRVTEDGKELYFVLNMSNEERTLPSKFTGYEDILTGEKAHKDMKGW DVQVLRN > DME ID: DME1718 DME Name: Sucrose phosphorylase (Spase) PDB ID: Not Available MKLQNKAILITYPDSLGHNLKDLDHVMDRYFNKTIGGIHLLPFFPSNGDRGFSPTRYDVV EPKFGSWEDVEKLSQKYYLMFDFMINHLSKKSSYFEDFEAKHDKSKYSDLFLSWDKFWPK GRPTKEDIDLIYKRKDKAPYQNIKFEDGTHEKMWNTFGPDQMDLDVRTKTTQDFIKHNLQ NLSKHGASLIRLDAFAYAIKKLDTNDFFVEPEIWNLLEKVNDYLKDTPTTILPEIHEHYT MPFKVAEHGYFIYDFALPMVLLYSLYSGNSTQLAAWLKKCPMKQFTTLDTHDGLGVVDAK DILTDDQISYTTNELYKIGANVKKKYSSAEYHNLDIYQINTTYYSALGNDDKKYFIARLL QIFAPGIPQIYYVGLLAGENDIQLLEKTKEGRDINRHYYDLDEIAEQVQRPVVKSLIKLL EFRNSVPAFDLEGSIKVETPSEHEIIVTRSNKAGTEVASTYVDFKNLDYQVKYNDQVFNF > DME ID: DME1719 DME Name: Alpha-galactosidase (melA) PDB ID: Not Available MSITINKNYYYINSKELSLIIEEREGDLLLRHLGRKITNYHGSNAVNERDHAFSGQLNPD IRTYSYDTQRQVLGLHGLGDFRQPSLKIQHGVSDVTRFEFSKAEVVKGISLESKLPYPHS LENAETLIFTLVDKVADLELKLYYTVVEDNNTIVTYSEVINNSNQAVVIHRALSAMADVP ARDYDVVTLQGAYAREKTVRRQRVEQGIFKVGSNRGASGHAQTPALILCDHEASEGAGEA LAFQLMYSGNFQTFVQKSQINEVRVAIGIEDENFTWELASNESFETPVALITYSHQGLTG VSQESQAFVTDYIIPKQFAHEERPILLNNWEATYFDFEKEKLLELAEDAKQVGAELFVLD DGWFGNRFDDNRALGDWFVNEEKLGGPLQDLIEKVHAKGLKFGLWFEPEMISVDSDLYRK HPDWAIQVPNYGHTYSRNQLVLNLANPDVVTYLKDVLDKILTDNAIDYVKWDYNRNITNI GNGANYLESQMLSHQYMLGLYDLVEFLTSKHENILFESCSGGGGRNDLGMMRYFPQVWAS DNTDAIARLTIQYGSSYLYPTISMGAHVSAVPNHQLERTTPLETRGDVAMMGNLGYELDL TSLTQEEKESIAAQIAHYKDIRPVVQFGQQYRLINPEAGSNEAAVQFNYENKVLATYVRI LSTIETVETTLKLKNLDQDANYMLQGTGQVYSGAELMYAGITVVLPQGDFLSKQFYFVKV D > DME ID: DME1720 DME Name: Phospho-beta-glucosidase (LBA1706) PDB ID: Not Available MNTYHVPHVFLWGVATSANQVEGAWNEEGKGISIADCERFNPNQDLDDYRKVNDMTTAEI ESAMQDKSSKSWGKRHGVDFYHYYQSDLELLAKMGINSMRTSIAWSRIFPNGDDARPNQK GLEFYDRLFTKMHELGIQPVVTLSHYEMPLNLVLNYDSWYDPKIIDYFYRFSKTVIDRYH DKVKYWLPINEIDSIIRHPYSSAGLVEDRFPNKNFKEVIYQSMHHQFVAAAKVTKYIHEN YLGHKVGSMITSTMVYPYNSDPRNMLKATQIMRESYNFSDVQLRGKYPQVLLKQMMEMGI HVKMSDKDLQLIKENTADFVAFSYYSSICTAHDTEGLQITKANRTIGVYNKYLPTSEWGW QIDPVGLRLIMINLYDRYQKPVFIVENGLGARDRLTYDFKIHDQYRIDYLRAHINEMLRS LTEDGIELMGYMIWGTTDMVSASTTQMSKRYGLIYVDLDDEGKGTCKRYLKDSYYWYQKL LSFKADIPVDYLN > DME ID: DME1721 DME Name: Glycosyl hydrolase (glyH) PDB ID: Not Available MKHFKQAVSLMALGVMQASGALAAGPATGNEVEARVSSILDNMNQAEKINFTRVNDGHMI PSLLKWGIQGTVAYDSSMGVHVNNATFGAQYPSQSALAATWSINRAKEFGLAIAYETRIS GGQQMLSPGVNLYRTPYNGRSAEYVSGEDPFLGAVLAPAIVNGIQAQGIQASGKHYLANE QEANRQAVNVVADERTLRELYLPGFESMVKNANVASIMCGFNKVNGDYACENHHLITEVL KGEWGYQGTVISDFNAIHDPFKGAWAGTDLDMPSGLQFTEANLLPYLWSGQLTQNVIDDK VKRNLRAVVSYDFQENLNTAKTLEHTEYGQRASLNAAREGIVLLRNADTAAGKPLLPLAR TARIAVIGDWANQAPASPFGTANSPPNSYVTELSGLQQLASNSANVTYLSALSLNPKAAV WYQPTSSGSGVSNAGVKAEYFSNTSLSGDPVLTRIEPGVNLNWTTSTNETSTGTTAVSGF SPTAGAFSARFSATIKPTVSGAHVFKVRADGPYKLWVDGKLVVQSDGVPYSSDVVNALTT SGKSAALVAGKSYNVKLEYRRVQGNFTPALGGLAGVQMSWASLRPPKDIASYDAVVIAAG TNYENEGEGSDHGYALPDQQAELIKFVTKANPNTIVVTHGGGVADMQPWAKKVGAALHAW FPGQQGGQALAEILYGKVNPSGKLPVTIDKKIEDNPSYASYPDPAAYRGDNPLTEIDYSE GLYMGYRGYDKKHAKPLYPFGFGLSYTTFGYSDLKLSTNVMTPGNTVNATFTLTNTGDKA GFEVAQLYIQPIAPQVDRPKKELKGFTKVYLEPGQSKTVSLPIDSRSLAYFVQNTDSWDV DAGKFKVWVGPDSENLTLQRTLVTLMPQHLTTRDSNPLPAPLQAAVQVSDSQAY > DME ID: DME1723 DME Name: Glycosyl hydrolase (glyH) PDB ID: Not Available MFKHLNALFIGLALFACTSGAVAQTIKPIETPVPVRPAGQKDVVGLTTPKLDVVRVGFIG LGMRGPGAVERFTHIPGTQIVALCDLIPERVAGAQKILTKANLPEAASYSGSEDAWKKLC ERKDIDLVYIATDWKHHAQMAIYAMEHGKHVAIEVPSAMTLDEIWALINTSEKTRKHCMQ LENCVYDFFELTTLNMAQQGVFGEVLHTEGAYIHNLEDFWPYYWNNWRMDYNQNHRGDVY ATHGMGPACQLLDIHRGDKMNYLVSMDTKAVNGPAYIKKTTGKEVKDFQNGDQTSTLIRT EKGKTILIQHNVMTPRPYSRMYQVVGADGYASKYPIEEYCMRPTQIASNDVPNHEKLNAH GSVPADVKKALMDKYKHPIHKELEETAKKVGGHGGMDYIMDYRLVYCLRNGLPLDMDVYD LAEWCCMADLTKLSIENSSAPVAIPDFTRGAWNKVKGYRHAFAK > DME ID: DME1724 DME Name: Glycoside hydrolase (cscA) PDB ID: Not Available MTQSRLHAAQNALAKLHERRGNTFYPHFHLAPPAGWMNDPNGLIWFNDRYHAFYQHHPMS EHWGPMHWGHATSDDMIHWQHEPIALAPGDENDKDGCFSGSAVDDNGVLSLIYTGHVWLD GAGNDDAIREVQCLATSRDGIHFEKQGVILTPPEGIMHFRDPKVWREADTWWMVVGAKDP GNTGQILLYRGSSLREWTFDRVLAHADAGESYMWECPDFFSLGDQHYLMFSPQGMNAEGY SYRNRFQSGVIPGMWSPGRLFAQSGHFTELDNGHDFYAPQSFVAKDGRRIVIGWMDMWES PMPSKREGWAGCMTLARELSESNGKLLQRPVHEAESLRQQHQSISPRTISNKYVLQENAQ AVEIQLQWALKNSDAEHYGLQLGAGMRLYIDNQSERLVLWRYYPHENLDGYRSIPLPQGD MLALRIFIDTSSVEVFINDGEAVMSSRIYPQPEERELSLYASHGVAVLQHGALWQLG > DME ID: DME1725 DME Name: Beta-galactosidase (bgaB) PDB ID: Not Available MSDTPSLTLSALLARRDWENPVVTQWNRLAAHAPLHSWRNEPSARDDAGSARRQTLNGLW RFSYFTAPEQVPQAWVTEDCADAVAMPVPSNWQMQGFDTPIYTNVTYPIPVNPPFVPQEN PTGCYSLTFEVDDAWLQSGQTRIIFDGVNSAFHLWCNGQWIGYSQDSRLPAEFDLSAALR PGQNRLAVMVLRWCDGSYLEDQDMWRMSGIFRDVTLLHKPETQIADYHVVTDLNAELDRA VLKVDVTLAGAGFADGEVVFTLWRKGEKCASVSRQPGSAIVDERGSWAERLTVTIPVETP ALWSAETPELYRLTMALLNPQGEVLEIEACDVGFRRVEISNGLLKLNGKPLLIRGVNRHE HHSENGQVMDEATMRRDIETMKQHSFNAVRCSHYPNHPLWYQLCDRYGLYVVDEANIETH GMVPMSRLADDPRWLPAMSERVTRMVQRDRNHPSIIIWSLGNESGHGANHDALYRWLKTT DPTRPVQYEGGGANTAATDIVCPMYARVDRDQPFPAVPKWSIKKWIGMPDETRPLILCEY AHAMGNSFGGFAKYWQAFRSHPRLQGGFVWDWVDQALTKRDEDGNTFWAYGGDFGDKPND RQFCLNGLVFPDRTPHPALYEAHGPQQFFTFTRVSTSPLVIEVQSGYLFRHTDNEVLNWT VARDGDVLVAGEVTLAMVPEGTQRLEIALPELNAGPGEVWLNVEVRQPRATPWSPAAIAA AGSSGRFRLRSLLLRQPRRRAAVLTQTDRILEIAHRQQRWQFDRASGNLTQWWRNGVETL LSPLTDNVSRAPLDNDIGVSEATKIDPNAWVERWKAAGMYDLTPRVLHCEAEQHAGEVVV TTQHVLEYRGKALFLSRKVWRIDEQGVLHGDIQVDMASDIPEPARIGLSVHLAETPENVR WLGLGPHENYPDRKLAAQQGRWTLPLEAMHTPYIFPTENGLRCDTRELVVGMHQLNGHFH FSVSRYSQQQLRETTHHHLLREEPGCWLNLDAFHMGVGGDDSWSPSVSPEFILQTRQLRY TFSWQQNP > DME ID: DME1726 DME Name: Glycosyl hydrolase (glyH) PDB ID: Not Available MKFTEGYWLRSERANGLFAAEAYAVEKIPGGMRVVAPVTRIGSRGDTLNMPVITIEFRAC AKGTISVKAWHYEGYDSHLPQFEKKEDIYDADVQISEEEAVLDTGLLKVRVSRKNFGYSF EADGKVLTSCGFRNLGYMRWDRQVSTMYPADNYLTEAHKPYMVNELSLSVGERVYGFGER FTAFVKNGQTVDIWNEDGGTASQLAYKNIPFYMTNRGYGVFVDCSDHVSFEVASEKVEYV GFSVPGESLSYYFFYGPQPKQILNAYTALTGRPALPPAWSFGLWLSTSFTTNYDEETTSF MIDGMAQRGIPLRVFHFDCFWMKAFHWCDFEWDKDCFPDIRGTLARYHEKGLKICVWINP YIAQGTPFFKEGAQNGYLLKRADGKGVWQTDNWQAGMGLVDFTNPDAVRWYTGKLKTLLD CGVDCFKTDFGERIPVNVSYYDGSDPHAMHNYYTFLYNRTVFNLLKEVKGEQEAVLFARS ATAGCQQFPVHWGGDCFANYPSMAETLRGGLSFAMSGFSFWSHDISGFESTATPDLYKRW AAFGLLSTHSRLHGSSSYRVPWNFDEEACDVVAFFTKLKCRLMPYLYAKAVEAHREGTPV MRPMVFEFMEDTAVAYIDTQYMLGEALLVAPIFREDSVCEYYLPEGTWTHLLDGGVKEGG IWRKETYDYFSLPLYVRENTLLALGADETRPDYAYEEGMSLRLYQLQDGQTAVCRVPDTA GEIVNVITARRKNAEITLCLEKAAGDIPLTIYDGECTKETVIPAGTGELQVSLED > DME ID: DME1728 DME Name: Beta-galactosidase (bgaB) PDB ID: Not Available MTAKLEWLDDPTVFRVGKLPAHSDHKVYRSAAEVVQGESSLISSLDGTWRFHFAKTPAER LINFEELNFNTENFDDIQVPGHIELQNFGQIQYINTLYPWEGKTYRRPPYALGADKTYPG IFSEASDNTVGQYVKTFTLPDNFNSHDVHIQFDGVEEAMYVWLNGQFVGYSEDSFSRAEF DLTPYLVNGENKLAVEVFKYSTAAFIEDQDMFRFSGIFRSVNLVAIPQVNVVDVHLKPVV SDDLRSGNLAIALTLAGELSDTTAQIIVNNPRGEAVLERTVTAEQTIQINESIENIALWS HKQPDLYELTVTIFDSDKQVIAVVPYAFGFRRLVKDANNHVTINGVPLHLNGVNRHEWSA VGGRSVTLDEMKTDIEIFKENNINAVRTSHYPNQIPWYGMCDEAGIYMMAETNLESHGTW QKMGAVEPSYNVPGSIPQWLDVVLDRAKSNFEQFKNHPSILFWSLGNESYTGDNLVAMDE YFKSVDDSRLTHYEGIFQNRVDEDRMSDVESRMYASPADIQEYLSNNPKKPYLNCEYMHS MGNSVGGFDEYVHLYDEFDTYLGGFIWDYIDQALYVTDEVTGKQVLRYGGDFDERHSDYE FSGDGIVFANRQPKPAIQEVSYYYGRYDN > DME ID: DME1731 DME Name: Carbapenemase (cphA) PDB ID: 1X8G; 1X8H; 1X8I; 2GKL; 2QDS; 3F9O; 3FAI; 3IOF; 3IOG; 3SW3; 3T9M MMKGWMKCGLAGAVVLMASFWGGSVRAAGMSLTQVSGPVYVVEDNYYVQENSMVYFGAKG VTVVGATWTPDTARELHKLIKRVSRKPVLEVINTNYHTDRAGGNAYWKSIGAKVVSTRQT RDLMKSDWAEIVAFTRKGLPEYPDLPLVLPNVVHDGDFTLQEGKVRAFYAGPAHTPDGIF VYFPDEQVLYGNCILKEKLGNLSFADVKAYPQTLERLKAMKLPIKTVIGGHDSPLHGPEL IDHYEALIKAAPQS > DME ID: DME1732 DME Name: New delhi metallo-beta-lactamase NDM-1 (blaNDM) PDB ID: Not Available MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQ HTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTH AHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPL KVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAF PKASMIVMSHSAPDSRAAITHTARMADKLR > DME ID: DME1733 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MFKKRGRQTVLIAAVLAFFTASSPLLARTQGEPTQVQQKLAALEKQSGGRLGVALINTAD RSQILYRGDERFAMCSTSKTMVAAAVLKQSETQHDILQQKMVIKKADLTNWNPVTEKYVD KEMTLAELSAATLQYSDNTAMNKLLEHLGGTSNVTAFARSIGDTTFRLDRKEPELNTAIP GDERDTTCPLAMAKSLHKLTLGDALAGAQRAQLVEWLKGNTTGGQSIRAGLPEGWVVGDK TGAGDYGTTNDIAVIWPEDRAPLILVTYFTQPQQDAKGRKDILAAAAKIVTEGL > DME ID: DME1745 DME Name: Cytochrome P450 109B1 (cyp109) PDB ID: Not Available MNVLNRRQALQRALLNGKNKQDAYHPFPWYESMRKDAPVSFDEENQVWSVFLYDDVKKVI GDKELFSSYMPQQSSAIGNSIINMDPPRHTQIRSVVNKAFTPRVMKQWEPRIQEITDELI QKFQGRSEFDLVHDFSYPLPVIVISELLGVPSEHMDQFKTWSDLLVSTPKDKSEEAEEAF LEERNKCEEELAAFFANIIEEKRNKPAQDVISILVEAEETGEKLSGEELVPFCTLLLVAG NETTTNLISNAMYSILETPDVYNVLRSHPELTPQAVEEALRFRAPAPVLRRIAKRDTEIG GHLIKEGDMVLAFVASANRDETKFDRAHLFDIHRHPNPHIAFGHGIHFCLGAPLARLEAK IALTSLISAFPHMECVSITPIENSVIYGLKSFRVKM > DME ID: DME1746 DME Name: Cytochrome P450 101B1 (cyp101) PDB ID: 3OFT; 3OFU MIPAHVPADRVVDFDIFNPPGVEQDYFAAWKTLLDGPGLVWSTANGGHWIAARGDVVREL WGDAERLSSQCLAVTPGLGKVMQFIPLQQDGAEHKAFRTPVMKGLASRFVVALEPKVQAV ARKLMESLRPRGSCDFVSDFAEILPLNIFLTLIDVPLEDRPRLRQLGVQLTRPDGSMTVE QLKQAADDYLWPFIEKRMAQPGDDLFSRILSEPVGGRPWTVDEARRMCRNLLFGGLDTVA AMIGMVALHLARHPEDQRLLRERPDLIPAAADELMRRYPTVAVSRNAVADVDADGVTIRK GDLVYLPSVLHNLDPASFEAPEEVRFDRGLAPIRHTTMGVGAHRCVGAGLARMEVIVFLR EWLGGMPEFALAPDKAVTMKGGNVGACTALPLVWRA > DME ID: DME1747 DME Name: Cytochrome P450 101C1 (cyp101) PDB ID: 3OFT; 3OFU MIPAHVPADRVVDFDIFNPPGVEQDYFAAWKTLLDGPGLVWSTANGGHWIAARGDVVREL WGDAERLSSQCLAVTPGLGKVMQFIPLQQDGAEHKAFRTPVMKGLASRFVVALEPKVQAV ARKLMESLRPRGSCDFVSDFAEILPLNIFLTLIDVPLEDRPRLRQLGVQLTRPDGSMTVE QLKQAADDYLWPFIEKRMAQPGDDLFSRILSEPVGGRPWTVDEARRMCRNLLFGGLDTVA AMIGMVALHLARHPEDQRLLRERPDLIPAAADELMRRYPTVAVSRNAVADVDADGVTIRK GDLVYLPSVLHNLDPASFEAPEEVRFDRGLAPIRHTTMGVGAHRCVGAGLARMEVIVFLR EWLGGMPEFALAPDKAVTMKGGNVGACTALPLVWRA > DME ID: DME1749 DME Name: Alpha-hydroxysteroid dehydrogenase (12AH) PDB ID: Not Available MIFDGKVAIITGGGKAKSIGYGIAVAYAK > DME ID: DME1750 DME Name: Alpha-hydroxysteroid dehydrogenase (12AH) PDB ID: Not Available MIFDGKVAIITGGGKAKSIGYGIAVAYAK > DME ID: DME1751 DME Name: Alpha-hydroxysteroid dehydrogenase (12AH) PDB ID: Not Available MIFDGKVAIITGGGKAKSIGYGIAVAYAK > DME ID: DME1752 DME Name: Alpha-hydroxysteroid dehydrogenase (12AH) PDB ID: Not Available MIFDGKVAIITGGGKAKSIGYGIAVAYAK > DME ID: DME1759 DME Name: Alpha-L-rhamnosidase (lrA) PDB ID: Not Available MPNITPSLLAPDHLRVNLQHFAYNIQAQPHFSWWNHSNRTGASQSAYQLTVFQRLQDRQN HNYLYDSGWVTSSNNTAVTAAKLSDQLVPGQLYYWQVRIKDNAGSISDFSQPAKLICADP SLPVKHGIWRQPQPKTAQELAHIGQVVFLRSPQLKINLSEVDTAVIVAVARGNEPVFAQS FDLYLNGHCLGVGSARQQEHDHGTEKTAIYYNVYEATDFLQDGANTVAALATASSDRQAF WCQLILYKHDGTKEVATTTDNTWRALDGSSAFGDYGVKIRTQYFGMVSENIDMRYYPQNW TDSAFDDHDWPLAWQNPYQLIADNEVLVPFRSENTERVEVHDRNKRVVTFSDQNYLLDLG KEIIGGLKVNLFSAFDQRVTVMMGEQLNDDGHVRHEMACGPDYIENWTLVKGQNQFTTLQ MKNFRYVELVGFEGDLPLDAINGWAMQQAFPDNESQFDSDSELLNREYELSKYTIKATNQ DVFVDSQARERRPYEGDLLVNANTSYSVSSNYSLARHSLDYLIDNPTWPEDYKLFAIEMA WLDYLYTGDDDLLQTRYTDLQYKLNRGKSAESFDGASQSFTGSLKNSQGVDNFDAAVGLV TNDGLVDWPISERDGFVEGTYNTPFNAIFHGAYATMAKIARVLHHPDDADRYQKRAEIIK TNLIDKLYDPQTGRFFDSLNADLSVNRHTSHHASAYALCYGVYTDQNMADRLSHFVANDG HFVGSIYFIYFMLKGLFEAGHAADAITLLTDPDNHKDHKSFAAILDSLKATIAPEAWSNA YKPNLTLSHPWGATPGLTIVQGVFGIVPLAPGFATFRVKVRPGNLKHLDLTTPSVKGLIT LHYRHEPTHQTLDVTVPMNTTAKVELPDDAQAIVVHDQYGKDWTASIEHDHDTLTIPMGR YQIQYQA > DME ID: DME1774 DME Name: Alkaline phosphatase (ALP) PDB ID: Not Available MERRNFLKNSLLAGLGSLLVPSVAQAQASESFGRKRAKNIIYLVSDGMSIGTLVMADLYS KRILGRSSAWFSLYEQKLAVKASMDMQSASSVVTDSSAASSSWGSGHRIINGMINVGVNG EQYTPILQKFKKAGKKVGCVTTVPITHATPAGFCTNSKERKAQPKIAENYLDLRFDVMMG GGDNYFNAGKRKDKQDMYVKYLEKGFTVVKNVSQMNAAPKNVPLLGVFDKDALPYTLDEN NTTKNATIPTLAQMTQKAIDMMADHKQGFVLQVEGGKVDWAAHGNDIGALLFDQLAFDDA VRVAIDFAKKDGNTLVVITSDHGNANPGLIYGKECNKNFDNLAHFLHTNDFTLQSINLTD SVSQVRDLLTHNFGNIPFSQEEAKEILSFYTEGKQEDGLYNYKKLPYRLLAEIQKKHTSV GWISMDHSSDYTELAMYGPGSQNLPPFIENYKMHNFLLEAAEVDMLEKY > DME ID: DME1775 DME Name: Glycosyltransferase (Gtf) PDB ID: Not Available MPEPQEVPALTPSASVIVPSYRGEARLPVLLGGLAQQDTTDFEVVVVIDGEVDASAAVLA GLGESTGLDLDVIVFPRNRGRVAALNAGHAAARGEVLIRCDDDLLPAPDFVSGHVARHAH HGPRGVVALANDVMPDSPYARAYGVRSMDHLIASAYAGDIEPWRLWSANCSLTRGTWEQV GEYSQEYAHYGMEDTDYGYRLHQAGIPLVIAPELQVAHLGAPTSTHDRVMRAFHSGASRR TFEARHGSALSLPSAGTGPWGRLVDGLSRAGDEPRYERATRAVDRLLPYVPRYVAEKLVA LCVESASLAGYRHAQDVTASF > DME ID: DME1777 DME Name: Cytochrome P450 RauA (rauA) PDB ID: 3WEC MTHTVDDTGDLALAVNPFDPTFKADPYPVYARLRTELPIHRSALGAWIVADYTSCDKVLR SRLFGKDFANSTFFDHLTSMMGEDMPPFLGLGIDGDARPFMLTDPPEHTRLRGLVSDAFT RSTTTSMDDIVLSAASSAVRHLEHCTDAVSEVAEPFPVEVLSSILGIPDKDRGRFSEWSN LVAGVLDINFAIPKEVADRRSAAIEESIDYFRTLATSGNAPEGLVRRLSEVSHGGDQLSV DEIAATCLLITVAGQETTSNTIGNMLITFSRHADQFEQVRANPQFIENAVAEVLRFEPPA HEAGRIALEDCEVSGANITKGDAVMVLLASGNREAVERGDTFSVTRPDVSSLSYGRGIHH CLGSALANSMLQHFLRELSQRYRSIEVAEPINYKPGMGLRGPETLSVAVSR > DME ID: DME1778 DME Name: Phospholipase C (plc) PDB ID: Not Available MKKKFLKGLCCAFVISITCLGASSKAYGWDGKKDGTGTHSMIVTQAVKVLENDMSKDEPE IVKQNFKILQDNMHKFQLGSTYPDYDPNAYKLFQDHFWDPDTDHNFSKDNLWYLSYSIKD TAESQVRKFTALARNEWEKGNYEKATWYFGQAMHYFGDLNTPYHAANVTAVDSIGHTKYE GFAEKRKDQYRINTTGIKTNEGFYADALKNSNFDSWSKEYCKGWAKQAKNLYYSHSTMKH TNEDWDYSASHALKNAQMGTAGCIYRFLYDVSKDLLPTENHKINGLMVVIKTANEIAAGT DDYVYFGIERKDGTVQEWTLDNPGNDFEANQEDTYILKIKKPSIKFSDINRMWIRKANFT PVSDDWKVKGIKVIADGSVQYEKQINKWIHGNEKYYIN > DME ID: DME1779 DME Name: Dipeptidylpeptidase IV (DPP4) PDB ID: Not Available MKKTFVRIATFLMLVCLFPVQLVQACSGFIIGKGLTTDGSILYGRTEDYPYPPNNGAHNK NYIVVPAATYAKGDMLVDESFGFTAPHLANEFKYTSTPDAARGDGSNGNFGAHGFNEKGV SMTATVTAIPNKKILAVDPLVTAGGLGEAILIDYVLPRVTSAREGIELIAKTIDEKGSAE GNIIVIADKNEVWYMEILSGHQYVAIKFPEDKYAIFANTYYLGHVDFTDTENVIASAKVE EVAKQAENYMMVDGKFHIAKSYGPENYADGDRSRTYAGIKLLDPASSVTYEDAVYDLLRQ PTDPSRRFSLQDTFALQRNRFEHLPEFRPDDEAGKVKQGDNGANDQAADATYKYALGNEN VIDAHVYQINSSLPSAFGGTVWLGLAQTRNTPYVPFYGIVTDTYEAFKNRSASYDANSWY WTVQNIDKMAISHPELFGTSIQEKWIALEKEWIAAQAALDAQYAGLSEDAAVALAPTVTE ATLARSAEIFAQLKAVEAEMMAKIEVVTTPSSSGTETSTSTSQSTSTSDTGGATDTSSSS GTVVSSDKKVTPTNKKGKSNLPSTGEQVSILLVALGVAGILTAIFLHRKKSNKE > DME ID: DME1780 DME Name: Phosphoenolpyruvate carboxykinase (pckG) PDB ID: Not Available MSLTKNPNVLKWVDEMVALCKPDNVVWIDGSKEQIDSLIEEVTSLPDDSWDKMYKLNPEK YPNCLYHRTRANDVARVEDRTFICSKEKSGAGPTNNWMAPDEMKALLTPMYDGVMKGRTM YVIPYSMGPIGSPLAKVGVEVTDSIYVVLNMNIMTRMGKQAFENLGDTSDDFVRGLHSKA DVDPEKRYIVQFPEENTIWSINSAYGGNVLLGKKCFALRIASFQGKNEAWMAEHMLILGV KKPNGDVKYITAAFPSACGKTNLAMLIPPEGYKKEGYEVFTVGDDIAWMKPGKDGRLYAI NPENGFFGVAPGTNEKSNYNALACTKNGAIFTNVALDNSDNTPWWEKLTENPPKDATEWK GEKVDGEAYTAAGNKLAHPNSRFTAPAQNCPCISPEFNNPEGVPVSAIIFGGRRATTAPL VYQSFDWTHGTYIGSAVSSETTAAATGAVGVLRHDPMAMKPFIGYNVGDYWAHWLEMGAR LGSKAPKIFNVNWFRTDDEGNFLWPGFGDNMRVIDWIIKRVENEVDAVETPIGYLPKPED INLKGIEDEVSADALKLLLTVNKDEWKKEIAEMRRYYDEDIKAKGGNIPQALYDELDMIE ANLNK > DME ID: DME1788 DME Name: Beta-glucuronidase (uidA) PDB ID: 3K46; 3K4A; 3K4D; 3LPF; 3LPG; 4JHZ; 5CZK MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADI RNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTP YVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTP NTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPH LWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDAD LRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLS LGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQG AREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLET AEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRV SAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQG GKQ > DME ID: DME1797 DME Name: Sulfide-quinone reductase (SQR) PDB ID: 3KPK; 3SX6; 3SXI; 3SY4; 3SYI; 3SZ0; 3SZC; 3SZF; 3SZW; 3T0K; 3T14; 3T2K; 3T2Y; 3T2Z; 3T31 MAHVVILGAGTGGMPAAYEMKEALGSGHEVTLISANDYFQFVPSNPWVGVGWKERDDIAF PIRHYVERKGIHFIAQSAEQIDAEAQNITLADGNTVHYDYLMIATGPKLAFENVPGSDPH EGPVQSICTVDHAERAFAEYQALLREPGPIVIGAMAGASCFGPAYEYAMIVASDLKKRGM RDKIPSFTFITSEPYIGHLGIQGVGDSKGILTKGLKEEGIEAYTNCKVTKVEDNKMYVTQ VDEKGETIKEMVLPVKFGMMIPAFKGVPAVAGVEGLCNPGGFVLVDEHQRSKKYANIFAA GIAIAIPPVETTPVPTGAPKTGYMIESMVSAAVHNIKADLEGRKGEQTMGTWNAVCFADM GDRGAAFIALPQLKPRKVDVFAYGRWVHLAKVAFEKYFIRKMKMGVSEPFYEKVLFKMMG ITRLKEEDTHRKAS > DME ID: DME1798 DME Name: Beta-glucuronidase (uidA) PDB ID: 3VNY; 3VNZ; 3VO0; 5G0M; 5G0Q; 5L77 MAFARGGLAQTASQTTSSPVRVGLSVDASALGHTIPPDYTGLSYEQAQMANPNYFSGANT QLAGFLRTLGRQGVLRIGGNTSEYTFWNRHAKPTAADEHLAAGPDKGHHAAAREVITPEA VNNLSEFLDKTGWKLIYGLNLGKGTPENAADEAAYVMETIGADRLLAFQLGNEPDLFYRN GIRPASYDFAAYAGDWQRFFTAIRKRVPNAPFAGPDTAYNTKWLVPFADKFKHDVKFISS HYYAEGPPTDPSMTIERLMKPNPRLLGETAGLKQVEADTGLPFRLTETNSCYQGGKQGVS DTFAAALWAGDLMYQQAAAGSTGINFHGGGYGWYTPVAGTPEDGFIARPEYYGMLLFAQA GAGQLLGAKLTDNSAAPLLTAYALRGTDGRTRIALFNKNLDADVEVAISGVASPSGTVLR LEAPRADDTTDVTFGGAPVGASGSWSPLVQEYVPGHSGQFVLHMRKASGALLEFA > DME ID: DME1808 DME Name: Beta-porphyranase A (GH86A) PDB ID: 4AW7 MSYKYIFLLSAFTLGVPPGIYCQGRNEVVVDYNTRRFLSGVSELDRSKYFNIHSTSDDDK DVGKFLADYQVGLGRKFWGPYSYAYNKTHEVGKYPQMKPYSGNISVKRYIATEHPYVQHI QGGIDVQAAGAWSAEYYSNSELVPEFFEPLNEPFVHANDAGFTVQGQAMRELMVDFYASI GKHIHNNPRLNGKMKVIGYAAAYPAWEDGNFNYWNTRMKMFIDRAGAYMDGFSVHLYDGI NVTGTDTKRSGSNSEAVLDMVEAYSYIKFGHVKPLAISEFGGIDNSKPDDSYDDISSVRS VSSFNHFLFNLMERQDNLFISIPFVSDKAEWHITAANNYTSYSAALFIPDNPQNLKNTTW RLNDKKYFFELWKNVKGERVDITSSNPDIQVQAFKDGGRLYIALDNLDDNPQTVYLNNKN SWKDVSNVTKRSLYVNYNAGIEYTEQNVPSMPESISIVPNQTIVLVADVSSSAFTNSIIR NKYYSSEYLKPISAGSSLSFPFTGIESGSGRASLRMSIGRPVSASKKPVVKINGTAVSVP DNWKGYGQSNRNIFFGMIEVPFDIQLLKNGDNNVDITFSDGGGHVSSMILQVEKYTVSTL QNGTFSEGLSAWQPLGNYGTVCVQTDNAGNNVACISGHAGLMQRVDMESGRTYRFSADVK TEGACKLKVMLQDMSTGTVYTEEFSSPGNYKAVSFDFNSTVKKVVCAIVCERQNDAAWID NIVLLPQN > DME ID: DME1815 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MENTFPQDFVFGTATASYQIEGAANEDGRCPSIWDTFSHTPGATLAGDTGDVATDSYHRW REDLALLKDLGVDAYRFSIAMPRIMPTPNGVVNDRGLDFYERIVDALLKSGIKPVVTLYH WDLPQYLGDEGGWLNRKTAYALADYTSVVANRLGDRVDTWTTLNEPWCSSYLSYGAKEHA PGLGLGPGAFPAVHHLNLAHGLMVQAVRAELGESAKCSVTLNLALNRGDADACHRLDLIS NRAFLDPMLRGRYPDELFAITKGICDWSFVQPGDLEQIHQSIDVLGINYYSTNLLAMGDR PQFPQSTEASTAPGASDVDWLPTEGPHTDMGWNIDPDGLHDLLVRVHDNYPEVPLMVTEN GMACKDQLVVNNDGDKAVHDADRIDYLQRHLAAARRAMSEGVPLTGYFVWSLLDNFEWYF GYAKRFGITYVDYATQERIPKDSFLWYRDFIASRS > DME ID: DME1816 DME Name: Glycerol/diol dehydratase (dhaB) PDB ID: Not Available MKRSKRIEVLDQRPVNKDGFIDEWPEMGFVSMHSPYDPKPSVKIEDGIITELDGKKRDEF DFLDQFIADYAIRADRAEASMAIPSLEIARKIVDIHVSRKEILEIVSGITPAKMVEVINY LNVVELMMGMQKMRARKVPGNQAHITNLKDDPVQIAADAAEGALRGFSEEETTMGVARYA PFSAMALLIGSQTGRPGVLTQCSAEEATELELGIRGLTTYAETLSVYGTEKVFVDGDDTP YSKAFLNSAYASRGLKVRFTSGAGSEVLMGSSEKKSMLYLECRCLYVTKGCGSQGIQNGS VSCIGVAAGVPAGIREVMGENLVAALLGLECASSNDQSFSNSDMRRTARTMLQFMPGTDF IFSGYAAEPNYDNMFAGSNFDAEDFDDYNVLQRDMQVDGGLRPVTEEDVIRVRHEAGKAV QAVFKYLGLTEVTDEQVEAVTYAHGSKDTLKRDVASDLMAADDMMKRGITGIDVVKALAE SGYTVLADNILNMLKQRVIGDYMQTAAILDKNFQVMSGVNTPNDYMGPGTGYRVSGKRWE EIKAIPHRINANDI > DME ID: DME1829 DME Name: Dihydroorotase (pyrC) PDB ID: Not Available MILIKNGRVIDPKSGMDETIDILIDEGKIVGLGKYKRSNEYEHVIEAEGKIVAPGLIDIH VHFRDPGLTYKEDIESGALAAASGGFTTVVCMANTKPTVDNKETLEYVLEKGRQTGIHVM SVAAVTKGMQGQELTDFRELKEAGAAGLSDDGIPIKDSKLMYEAMAKARDAGMPVSLHEE DPDYVIQAGINKGTVSDELGIGGAMALSEQLMVARDCLLALETGARVNIQHVSSRISVEY IRLAQKLGADVWAEATPQHFSLTEETALEKKTLAKVNPPLRTQEDRYGILEGLKDGTIQI IATDHAPHSTEEKEKPITQAPSGLIGLETSLALGITNLVRTGILTMEYMLKKMTLNPARL YGLDVGYIAKGAPADIVIFDEFEKWKVEKFHSKSCNSPFIGEELYGKVKYTICAGRIVYE DK > DME ID: DME1830 DME Name: Beta-glucuronidase (uidA) PDB ID: 3K46; 3K4A; 3K4D; 3LPF; 3LPG; 4JHZ; 5CZK MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADI RNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTP YVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTP NTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPH LWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDAD LRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLS LGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQG AREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLET AEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRV SAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQG GKQ > DME ID: DME1835 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MMDMKNQVVLDWNQYVALARQTVAEGCVLLENKDQALPLVKDEKVAVFGRIQNHYYKSGT GSGGMVNVSKVYGIVDGLRESGQVILDEELIRIYQDWEETHPFNEGEGWGNEPWCQEEME LTDEVVEAAGKRSETAIVIIGRTAGEDKDASDTKGSYQLTDVEEDLLTKVRKNFDKMIVL LNVGGLLDMSFTDRYQPEAVMYVWQGGMVGGLGTADVLTGAVSPSGHLTDTIAYKVADYP STPYFGDPDKNYYSEDIYVGYRYFETFAKDSVRYPFGYGLSYTTFEKSVVVFANEPEKQQ FTLHVTVSNVGLKKGKDVVQIYAEAPQGKLGKADKVLVGFAKTKELAPGESEEVEITVPY SRFASYDDSGITGHAYAFVLEAGTYHVFAGENVRSAECAGAFELADGLVIEQLCSALAPV EAFDRMKAAETENGYQVMMEAAPHHASNEKQRRQDHLPQEIRQTMGMHTLSDVADGSIGM DKFISELTDDDLTCIIRGEGMGSSLVTPGTAAAFGGVSKSLINRHGIPSVCCSDGPSGMR LDCGVKAFSLPNGTIIGCTFNTELVKELYTCTGYEMIAQKVDCLLGPGMNIHRHPLNGRN FEYFSEDPYVTGCFAGAMLEGLHAAGVTGAAKHFCANNQEMRRHFADPIVSERALREIYL KGFEMIVRSGVCDAIMTTYGPVNGVWTAGNYDLCTTILREEWGFKGIVMTDWWASINERG QEPDKINFAAMARAQNDIYMVCPDGSTNASGDNTAAALVDGRLKRAELQRNAANICGFVL DTEAMRRAMGCPTEVSIINRPAEPDDVDLSEVEFVRLDGDYELRLDTKESKAGVNYVLPF DVQKKGIYEIELIGSSDLSELAQMPCTLYYTNIPILSFTFHGTNGEDMVIKKEFDLHTRF SVMRLNVGKNGLHLKQIRFRYLREGKIWN > DME ID: DME1837 DME Name: Azoreductase (azoR) PDB ID: Not Available MSKVLYIKANIKNEGESRTFKVSDSFVEEYKKNNPEDEIITLDLYKENIDFLRADDLGKL FGPKDEESKNNSILKYAYQFADADKYIIAAPMWNLSFPAILKAYIDYVSVSGITFKYTAE GPVGLLNNKKAVHIVSRGGGYDNSPYEMGDRYLRTILGFFGIKDIETIAIDNLDVMGVNV EEKVEEGIEKAISLAKKF > DME ID: DME1842 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MKVIKIFSACLFLLPFVSCTQVTNDKGDTAIEKKVEALLSKMTLEEKLGQMNQITSYGNI EDMSGLIKQGGAGSILNETDPVRINALQRVAIEESRLSIPLLMARDVIHGFKTIFPIPLG QAASFNPQVAEDGARVAAIEASSVGIRWTFAPMIDIARDPRWGRMAEGCGEDTYLTTVMG VAMVKGFQGDSLNSPTSIASCPKHFVGYGAAEGGRDYNSTFIPERRLRNVYLPPFEAASK AGAATFMTSFNDNDGVPSTGNSFILKDVLRSEWGFDGLVVTDWASSTEMIAHGFAADSKE VAMKAVNAGVDMEMVGNTFVKELPGLIKEGKVKEAEIDNAVRNILRIKYRLGLFENPYVD EKANVLYAPSHLEAAKQAATESAILLKNDHETLPLQSSVKTIAIVGPMANAPYDQLGTWV FDGEKSHTMTPLTAIKELADDKVQIIYEPGLTYSRDKNIAGVAKAAAAAARADVILAFVG EEAILSGEAHCLADLNLQGAQSELISALAKTGKPVVTIVMAGRPLTIGKETELSSALLYS FHPGTMGGPALADLLFGKAVPSGKTPVTFPKMVGQVPVYYAHNNTGRPATRSEVLIDDIA LEAGQTSLGCTSFYMDAGFDPLFPFGYGLSYTTFQYGNVKLSSDNLKKDDVLTVTFDLEN TGKYEGTEVAQLYVQDMIGSVTRPVKELKRFTRVTLKPGEKKTVSFELPISELAFWNIDM VKTVEPGDFALWVAPDSQSGEKNLFKVVD > DME ID: DME1843 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MPARLSRRDLAGAAVLTAALGATIAATEADAAPKSQSGFPDGFLWGTATAAYQVEGAVHE DGRGPSIWDTFSHLPGKIRDGSTGDVSVDHYHRYKEDVALMKALGATSYRFSIAWPRVFP DGTGTPNPKGLDFYDRLVDELLKAGIKPFATLYHWDLPQALQDRGGWQSRDTAQAFGAYA GYVANKLGDRVENFFTLNEMLTFVEHGHAAGVFAPGLTLPPQGVNQVRHHAVLAHGLGVQ AMRASARRPIRIGPAENITIGIPAVETPENIRAAEIATREFNAPYLTVMLEGRYTDAYLA ATGADAPKFTAEDLKIIASPVDFVGLNVYTPSFFVVATDAAPHYRALPLPSSYPHMASPW LTIGPEALYWAPRHAATLWNAKEIYITENGTSSADQLAEDGQIYDTDRIMYLRNYLTQLQ RATAEGVPVRGYFLWSLLDNFEWADGYATRFGLVHVDYTTQKRTPKLSAAFYREVIARNA VA > DME ID: DME1846 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MKKTLLTICLVWMCFSLSAQKIIDLSGKWSFSIDRQDNGEKEKWFSHTLNDFINLPGSMP EKLKGDEVTAKTQWTGSLYDSSYYYNPYMEKYRKEGNIKFPFFLTPDKHYVGAAWYQKEV NIPADWKGERILLFLERPHIETTVWVNGQKTGMQNSLCVPHQYDITRYVRPGKCTITIRV DNRIKEINVGPDSHSITDQTQGNWNGIVGRICLQTTPKTYFDDIQIYPEPEQKLARVKVV IKGTGTAKVKLSAESFNTDKKHIVPAIQQEIKLNKGVTETEMVLPMGNDMLLWDEFHPAL YKLKAEVTNGKKTEIKEIQFGIRRFEIKGKWFYVNGRKTQLRGTVENCDFPLTGYAPMDV ESWERVFRICRSYGLNHMRFHSFCPPEAAFMAADRVGFYLQPEGPSWPNHGPKLGLGQPI DKYLMDETIALTKEYGNYASYCMLACGNEPSGRWVEWVTKFVEYWEKKDPRHVYTGASVG NGWQWQPRNQYHVKAGARGLTWSKKQPSTQDDYRFQNHLDTVRQPYVSHETGQWCAFPNF NEIRKYTGVNKAKNFEIFKDILADNHMSDQAHLFMMASGKLQALCYKYEIEKTLRTPDYA GFQLLALNDYSGQGTALVGVLDVFFEEKGYINSAEWRRFCSPTVPLMRTDKFVYNNKEIL KADIEIAHFGAEALKQAEIVYTLKDEYGKVYAQGTLATQDIPVGNLNRTGSLEFPLTDIQ EAKKLNLEIRIMGTEAVNDWNFWVYPAQVTIAEGKVYTTDTLDSKALEILQNGGNVLITA AGKVSYGKEVVQQFTPVFWNTSWFKMRPPHTTGILVNPKHPLFRQFPTEYHSNLQWWELL NRAQVMQFTHFPPAFQPTVQSIDTWFISRKIGMLFEANVLNGKVLMTSMDITSQPEKRIV ARQMHKAILDYMNSDQFRPQFTVTPQQISELFTKTAGDIKSYTNDSPDELKPKIN > DME ID: DME1847 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MTLTFPQDFTFGTATAAYQIEGAVTEDGRCPSIWDTFSHTPGATIAGDTGDVATDSYHRW REDLALLKDLGVDAYRFSIAVPRIISTPDGVPNEKGLDFYEGVVDALLEAGIKPVVTLYH WDLPQYLGDEGGWLNRRTAYALADYAGIVAKRLGDRVDTWTTLNEPWCSSYLSYGAKEHA PGLGLGPGAFPAVHHLNLAHGLMTQAVRAEVGDKAKCSVTLNLQFNRGDADACHRLDLIS NRAFLDPMLRGRYPDELFSITKGICDWDFIQSGDLELIHQPIDVLGINYYSTNRVAMSDR PQFPQSTEASTAPGASDVDWLPTEGPHTDMGWNIDPDGLHDLLVRVHDNYPEVDLVVTEN GMACKDQLTVNEDGTKSVHDPDRIDYLKRHFAAAKRAIDEGVPLTGYFVWSLLDNFEWYF GYAKRFGITYVDYATQERIPKDSFMWYRDFLASRKG > DME ID: DME1851 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MTTVSTARDRRITRALRIIAALTVIAMIATIAGLGLVWVRVHDTANPAGSPQSATTASHL DTLRRSAAPQPDITPAAKAKRTVAAMSMEERVGQLVMAPLNAGTDPSSLASTIRDRHVGS VLIIGNWNNGVASVRQATDALQSYAPANIKLLMTTDQEGGLVQHLQGAGFSTMPSAVEQG RMSTDQLRQSAAVWGNQLAQAGINIDLAPVVGTVTVPRASNAPIGALNRDFGLDAAGNAA HASAFVLGMRDSNVATSIKHYPSLGSVTGNTDFTADGILDTTTVLDGDVVNAFGTVIADT QPAMVMMSLATYQAIDASAPAAFSPTIIDGYLRARQGYQGVVTSDSLSAVALGGISPDQL GVRLVEAGGDLACIGAADYVTPILDGLNAKATTDAAFAAKVTRSAERVLTLKYQMGLAH > DME ID: DME1852 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MTMIFPKGFMFGTATAAYQIEGAVAEGGRTPSIWDTFSHTGHTLNGDTGDVADDFYHRWE DDLKLLRDLGVNAYRFSIGIPRVIPTPDGKPNQEGLDFYSRIVDRLLEYGIAPIVTLYHW DLPQYMASGDGREGGWLERETAYRIADYAGIVAKCLGDRVHTYTTLNEPWCSAHLSYGGT EHAPGLGAGPLAFRAAHHLNLAHGLMCEAVRAEAGAKPGLSVTLNLQICRGDADAVHRVD LIGNRVFLDPMLRGRYPDELFSITKGICDWGFVCDGDLDLIHQPIDVLGLNYYSTNLVKM SDRPQFPQSTEASTAPGASDVDWLPTAGPHTEMGWNIDPDALYETLVRLNDNYPGMPLVV TENGMACPDKVEVGTDGVKMVHDNDRIDYLRRHLEAVYRAIEEGTDVRGYFAWSLMDNFE WAFGYSKRFGLTYVDYESQERVKKDSFDWYRRFIADHSAR > DME ID: DME1859 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MEKWARIKYTPNLPLGENGERVTASQKHIELSCEAACEGMVLLKNDRNVLPIRKGTRVAL FGKGVFDYVKGGGGSGDVTVPYIRNLYEGLSQYTSDISIYDKSVRFYQEYVADQYRLGIA PGMIKEPALPEDILADAAAYADTAIIAISRFSGEGWDRKVAGVDREIKCEAKDLVEQGNK IFDHGDFYLTNAEKKMVKMVKENFSSVIVVMNVGGVVDTTWFKKDDQISSVLMAWQGGIE GGLAAARILLGKVNPSGKLSDTFAARLEDYPSTEGFHEDDDYVDYTEDIYVGYRYFETIP GAKEKVNYPFGYGLSYTTFLLEDYKAEPFVASAADEVGKSDSDLADAIVASVTVTNIGKI PGKEVVQLYYSAPQGKLGKPAKVLGGYAKTRLLQPGESQRVTIALYMEDMASYDDLGKVK KAAWLLEKGEYHFFLGTSVRDTRLLDYTYELSKNIIVEQVSNKLVPTSLPKRMLADGTYE ELPQTEPVDTYATIFPRPKNWKETIEHDVLKTPVVRPQDRFQLFLPPKEGDPKKFIEVAE CKVTLEDFIAQLSNEQLASLLGGQPNVGMANTFGYGNLPEVGVPNAQTCDGPAGVRIAPE VGVVTTAFPCSTLLACTWNEDICYEVGVAGGEEAKECNFGAWLTPAVNIHRSPLCGRNFE YYSEDPFLAGKQAAAMVRGIQSNNIIATPKHFALNNKESNRKGSDSRASERAIREIYLKA FEIIVKEQSPGASCLQYNIVNGQRSSESHDLLTGILRDEWGFEGVVVSDWWGFGEHYKEV LAGNDIKMGCGYTEQLLEAIDKKALKRKDLEKRQSESSRCFSNSTKLKAA > DME ID: DME1861 DME Name: Linoleic acid reductase (cla-r) PDB ID: Not Available MADISPKPVKITETVLRDAHQSLIATRMPTSIMLPIIDKMDQVGYNAVECWGGATFDACL RFLKEDPWDRLRQLRDGFKNTKLQMLFRGQNILGYSQYPDDVVEYFVQKSIANGIDIIRI FDCLNDIRNLQTAVNATNKEKGHAQVALSYTLGEAYTLDYWKDIAKRIEDMGASSICIKD MAGLLVPAKASELVSALKESTSLPIELHTHYTSGVASMTYLKAVEAGCDIIDCAMSPFAL GTSQPATEVMAAAFEGTPYDTGFDQELLSEIADYFRPYREECIESGLMSTKVLGVNINTL RYQVPGGMLSNLISQLKEQGKEDKLREVLEEVPRVRKDLGEPPLVTPSSQIVGTQAVFNV LMGERYKVVTEQTKDILLGKYGQTVKPFNPEVVEKALGAELRYAITCRPADLLEPGLKKF EEECARWKQQDEDVLSYALFPKVATEFFEYREAQQTKVDPAKADKENKAYPV > DME ID: DME1864 DME Name: Flavin adenine dinucleotide dehydrogenase (fadd) PDB ID: Not Available MDMTFFRAALLGACVLLSGCDSATTPASPASTATVLDGKTMGTFWRVSVIGVDEAKAEAL RAKVQAQLDADDRLLSTWKNDSALMRFNHAADTRPWPVSEAMVDIVTLSLRIGAKTHGAM DITVGPLVNLWGFGPDKQPVTTPDAQAIAAAKARTGLQHLQVINQSGRQFLQKDIPDLFV DLSTVGEGYAADHLARLMEQEGISRYLVSVGGALVSRGMNGEGKPWRVAIQKPTDRENAV QAIVDINGHGISTSGSYRNYYELDGKRISHVIDPQTGQPITHKLVSVTVIAPTALEADGW DTGLMVLGPEKAQQVVREQGLAVYMIVKEGEGFKTWMSPQFRTFLVGEKN > DME ID: DME1865 DME Name: Flavin adenine dinucleotide dehydrogenase (fadd) PDB ID: Not Available MDMTFFRAALLGACVLLSGCDSATTPASPASTATVLDGKTMGTFWRVSVIGVDEAKAEAL RAKVQAQLDADDRLLSTWKNDSALMRFNHAADTRPWPVSEAMVDIVTLSLRIGAKTHGAM DITVGPLVNLWGFGPDKQPVTTPDAQAIAAAKARTGLQHLQVINQSGRQFLQKDIPDLFV DLSTVGEGYAADHLARLMEQEGISRYLVSVGGALVSRGMNGEGKPWRVAIQKPTDRENAV QAIVDINGHGISTSGSYRNYYELDGKRISHVIDPQTGQPITHKLVSVTVIAPTALEADGW DTGLMVLGPEKAQQVVREQGLAVYMIVKEGEGFKTWMSPQFRTFLVGEKN > DME ID: DME1866 DME Name: Flavin adenine dinucleotide dehydrogenase (fadd) PDB ID: Not Available MDMTFFRAALLGACVLLSGCDSATTPASPASTATVLDGKTMGTFWRVSVIGVDEAKAEAL RAKVQAQLDADDRLLSTWKNDSALMRFNHAADTRPWPVSEAMVDIVTLSLRIGAKTHGAM DITVGPLVNLWGFGPDKQPVTTPDAQAIAAAKARTGLQHLQVINQSGRQFLQKDIPDLFV DLSTVGEGYAADHLARLMEQEGISRYLVSVGGALVSRGMNGEGKPWRVAIQKPTDRENAV QAIVDINGHGISTSGSYRNYYELDGKRISHVIDPQTGQPITHKLVSVTVIAPTALEADGW DTGLMVLGPEKAQQVVREQGLAVYMIVKEGEGFKTWMSPQFRTFLVGEKN > DME ID: DME1867 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MEIHELQQLLSEMSLQEKIGQMVQLTGAYFDKEAVLTGVVGEQLPPEWIIQYAGSVLGVI GKDKIYDIQSRYMEQHPHHIPLLFMADVIHGCRTIAPIPLGQACSFHPELVSEAASIAAS EASSEGLRATFSPMIDVSRDPRWGRMMESFGEDPYVNGIMGKAMVDGYQQKADTGIAACL KHFAGYGAVNAGREYNDVEISQRTFLEQYVKPFRMALKAKPAMVMTAFNAIDRKPISGNK ELLKGLLRDKEGFEGTVISDWGSIGQLEEQGVAADMEEAAIQASEAGVDIDMMSPAYMLC LEKLVESGKIPEAFVDESAFRVLMMKNQLGLFENPFAGLGKSGKLTLHNREKAYQLAGES CVLLKNDKILPLSMKKKVIWAGPYTTSRELLSRWSIFGEHEAVETIEDVLQKKQIEVECI TGCNILSDAECKVWQVEQELSGKPRDEQWLETITHEDTVVCVLGEHESQSGEAASRAFLT LPEEQQVLFEKIAERTSNIVTVIIAGRPLDLRRISEKSKAVIMAWRPGTMGAEAIIDIVY GRINPSGKLSVSIPWCVGQVPISYWDVKTGHILTEDNSENRFTSRYMDIPNTPLYPFGYG LSYTEFDISDVDVQIGQDKKVHVHCNVCNTGNVAGAEVVQCYYETLYASVVRPKKELVRF QKVFLEPGEKKDVDFFIDQEEFSYYGKNMETVSSGMKLRISIGNSSDHLVSENIIQE > DME ID: DME1868 DME Name: Flavin adenine dinucleotide dehydrogenase (fadd) PDB ID: Not Available MDMTFFRAALLGACVLLSGCDSATTPASPASTATVLDGKTMGTFWRVSVIGVDEAKAEAL RAKVQAQLDADDRLLSTWKNDSALMRFNHAADTRPWPVSEAMVDIVTLSLRIGAKTHGAM DITVGPLVNLWGFGPDKQPVTTPDAQAIAAAKARTGLQHLQVINQSGRQFLQKDIPDLFV DLSTVGEGYAADHLARLMEQEGISRYLVSVGGALVSRGMNGEGKPWRVAIQKPTDRENAV QAIVDINGHGISTSGSYRNYYELDGKRISHVIDPQTGQPITHKLVSVTVIAPTALEADGW DTGLMVLGPEKAQQVVREQGLAVYMIVKEGEGFKTWMSPQFRTFLVGEKN > DME ID: DME1869 DME Name: Glycerol/diol dehydratase (dhaB) PDB ID: Not Available MKSKRFEVLAARPVNQDGYVQEWPEVGLIAMNSPFDPKPSIKIENGVITEMDGKCRADFD MLDTFIADHAIRLGNAEKAMAMDSLEIARKIVDINVSREEILDITLSLTPAKLTEVVGKL NIVEIMMGMTKMRARMMPANQCHVTNVRDNPVQIAADAAEAGVRGFAEMETTVAVARYAP FNAMALFVGAQVGRPGVMTQCALEEATELQLGMRGFTTYAETISVYGTEPVFMDGDDTPY SKAFLASCYASRGLKMRFTSGTGSEVQMGYAEGKSMLYLEARCLAVTKGAGVQGTQNGSV SCIGVPAGVPGGIRAVAAENLIAMLLDLESTTSNDQTFTHSDLRRVARTVPQLFSGTDYI CSGYSATPNYDNMFAGSNWDAEDYDDWTIIQRDMKIDGGLQPVREEDVLKARNKAARALQ GMFRELGLPEITDAEVEAATYANGSNDMPERNVNEDLKAIEDMMARKVTGVDFVKALDRA GFPDVAHNIYNMLRQKVAGDYLHTASIFDEQFHVLSAVNVPNEYHGPMTGYQISEERWNQ LKNIPNAIRPEDI > DME ID: DME1873 DME Name: Azoreductase (azoR) PDB ID: 1TIK; 1V4B; 2D5I; 2Z98; 2Z9B; 2Z9C; 2Z9D MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALR PSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFR YTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYG PEMAAKAQSDAKAAIDSIVSA > DME ID: DME1880 DME Name: Beta-lactamase (blaB) PDB ID: 1ONG; 1Q2P; 1RCJ; 1SHV; 1TDG; 1TDL; 1VM1; 2A3U; 2A49; 2G2U; 2G2W; 2H0T; 2H0Y; 2H10; 2H5S; 3D4F; 3MKE; 3MKF; 3MXR; 3MXS; 3N4I; 3OPH; 3OPL; 3OPP; 3OPR; 3V50; 3V5M; 4FCF; 4FD8; 4FH2; 4FH4; 4GD6; 4GD8; 4GDB; 4JPM; 4MBF; 4MBH; 4MBK; 4R3B; 4ZAM; 5EE8 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR > DME ID: DME1881 DME Name: Metallo-beta-lactamase (blaM) PDB ID: 3PG4; 3RKJ; 3RKK; 3SBL; 3SFP; 3SPU; A/B/C/D/E=27-270; 3SRX; 3ZR9; 4EXS; 4EXY; 4EY2; 4EYB; 4EYF; 4EYL; 4GYQ; 4GYU; 4H0D; 4HKY; 4HL1; 4HL2; 4RAM; 4RAW; 4RBS; 4RL0; 4RL2; 4RM5; 4U4L; 5A5Z; 5JQJ; 5K4M; 5N0H; 5N0I; 5NBK; 5O2E; 5O2F; 5WIG; 5XP6; 5XP9; 5ZGE; 5ZGF; 5ZGI; 5ZGP; 5ZGQ; 5ZGR; 5ZGT; 5ZGU; 5ZGV; 5ZGW; 5ZGX; 5ZGY; 5ZGZ; 5ZH1; 5ZIO; 5ZJ1; 5ZJ2; 5ZJ7; 5ZJ8; 5ZJC; 6C6I; 6CAC; 6D1A; 6D1B; 6D1C; 6D1D; 6D1E; 6D1F; 6D1G; 6D1H; 6D1I; 6D1J; 6D1K; 6EFJ; 6EX7; 6IBS; 6IBV; 6MDU; 6MGY; 6MGZ; 6Q2Y; 6Q30; 6RMF MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQ HTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTH AHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPL KVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAF PKASMIVMSHSAPDSRAAITHTARMADKLR > DME ID: DME1887 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MEDRVLDWAVYEKTAREMAAEGLVLLKNDNKALPLKQGETVSVFGRMQNHYYKSGTGSGG MVNVARVVGILDALNECKDVNVNQKLAETYAAWDKEHPVELGLGWGQEPWSQAEMPVTEE LVQEAAGESDSAIVIIARTAGEDKDNTLEKGAFMLTDIETDMLRLVRENFQKMVVLLNVG GLIDMSFLDTISPDACMYVWQGGMVGGYGVADVLVGDVSPSGKLTDTIAYDIKDYPAYDN FGGEERNFYAEDIYVGYRYFETFAKDKVRYPFGYGLSYTDFKIGVKHASLDFEKGVANIC VKVTNTGKRLGKEVVQVYGEMPQGRLGKPSRVLIDFAKTKELVPGLSDELKFEIPLDRMA SFDDSGVTGHRNCYVLEAGDYTIHVGNSIRNTTECLFFELAEIVELQKLQEALAPYEKFD RMKPFCDENGRMLIEYEETPLVTVDMYDRREQELPEEIPVTGDKGIMLLDVREGRATMDE FIAQFDDEDLACFVRGEGMGSSLVTAGTASAFAGVSPNLIAHKIPSVCCDDGPSGMRLDS GMKAFSLPNGTLCGCSFNKELNTRLYALLGLEMTANKVEVLLGPGMNIHRHPLNGRNFEY FSEDPYLTGSIATAQLEGLKSSGVSGTIKHFCGNNQEYHRHTTDSVISQRALREIYLKGF EIAVKSGYADSVMTTYGLVNGLYTAGSYDLNTTILRNEWGFTGVVMTDWWASINRRGMEP DANDFATMIQAQNDMYMCCPDGSKNMGGDNVIEALQDGRILRAELQRIAKNVCNFAMNTN AFKRLVGEPVEVEIINRPKQADDFSIDDVEYINVDRDILIDLTEKASTADTNYVIALDVE HPGEYEVSLRGSSTLEKLAQLPCTLFFNGFPVSNFTFNGTDGKDVVIRKEVKFYGRFNVL RLYVKSNGLDLKDIKFSFEKEF > DME ID: DME1904 DME Name: Glycerol/diol dehydratase (dhaB) PDB ID: Not Available MRSKRFEYLDQRPVNQDGYAKEWPEVGFIAMNSPFDPTPSIKIVNGEVVEMDGKTKDEFD MLDAFIARYAINLDFAEEAMATDSLEIARMLVDINVNRQECLKYTTAVTPAKLVEIVGNL SVLEAMMGITKMRCRLKPANQCHVTNVKDNMVQIAADAAEAAVRGFAEMETTVGIVRYAP FNAIAIMLGANVGRPGILTQCAVEEATELDLGMRGYTAYAETVSVYGTEDVFMDGDDTPW SKAFLASCYASRGVKMRFTSGTGSEVQMGMAEGKSMLYLEARCLGVTRGAGVQGTQNGSV SCIGVPAAVPGGIRAVACENLIAAMLDLENASSNDQSFTHSDLRRVARSIPQFIPGTDYI CSGYSSTPNYDNMFAGSNWDADDYDDWCVIQRDLRVDAGLLPAREEEVVAARNKAAKAIQ ALFRELGLPEITDEEVEAATYARGSQDMPDRDVVADLKAATDMLDRGVTGIDFVKALYKG GFEDVAESIFNIQKAKVVGDYLHTASMLDDKFHVISAVNSPNCYEGPMTGYQISPELWEK ISDIRTAVDPAKL > DME ID: DME1905 DME Name: Cytochrome P450 147G1 (cyp147) PDB ID: Not Available MNAETAWAEAMKFENRPNPYPYFDELRKTPVAKVAEKTYVVTGYRELLALAHDPRISSDI TRSPSGFGGEAPQPEPGSEHVQAYGQDASIIVSDPPDHDRARRQVMRHFAPPHSPDLIPS MEPFVVRLANDLLNQASARGSTRLDVVEDFAYPIPVAVICKILGVPIEDEPKFHAWIFDF MAGTDLGPEGDTEEGQVLAEKGRVSTAALTDYLGDLVRSYAKTPGEGLLSKLLHDDGPDG PMSVPETTANALLLLVAGHDSTVNTITNCVMTLLRNPGSWDLVRQRPELIPRTIEEVQRL QSAVQFFPSRSATDEIEIGGTVIPAGSAVHLIYAAANRDPRRFDNPNRFDPLREDNEHFG WGSGIHTCMGGPLARLEVNLAVEIFLRRVQSPKLVVDPPPYRHNQIFRGPRHLWVDFAAI TE > DME ID: DME1906 DME Name: Alcohol dehydrogenase (ADH) PDB ID: Not Available MKAMVYHGANDIRFEEKPRPQIIDPTDAVVKIVKTTICGTDLGIWKGKNPEVADGRILGH EGIGIVEEVGEAVKNIKVGDKVIISCVSKCCTCDNCKIQLYSHCRNGGWILGYIIDGTQA EYVRTPYADNSLVPLPDNVNEEVALLLSDALPTAHEIGVQYGDVKPGDTVFIAGAGPVGM SALLTAQLYSPAAIIVCDMDENRLKLAKELGATHTISPASGDVSKQVFAIVGEDGVDCAI EAVGIPATWNMCQDIVKPGGHIAVVGVHGQSVDFKLEKLWIKNLAITTGLVNANTTEMLM KAISSSSVDYTKMLTHHFKFSELEKAYDVFKHAAENQAMKVVLEAD > DME ID: DME1908 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MERYKDKQLSAYERAAALADTLSTEEQAQQLKYDAPAIEKAGLPSYNWWNEGLHGVARAG TATVFPQAIALAAAFDKDMMCRVGEVVSTEARAMYNSAAKHGDTDIYKGLTLWAPNINIF RDPRWGRGHETYGEDPYLTSRLGVNFVKGIQGEEKYLRAAACAKHFAVHSGPESLRHEFD ARVSEKDLEETYLPAFKALVKEGRVEGVMGAYNRVNGEPSCASEKLMGKLREWGFDGYFV SDCGAIRDFHTNHKITDTAPQSAAMALKAGCDVNCGNTYLHILAALEEGLITKQDIRTAC IHALRTRIRLGQLDDNEFDDLPFDIIACDGNKALSLEAAEKSMVLLHNDGILPLDKSRIS SIAVIGPNADSRAALLGNYEGTPDRSVTFLEGIQDAFDGRVYYAEGCQLFRDRTQGLALP GDRYAEAVAACEAADVTVVCVGLDSTLEGEEGDTENKSGDKPDLRLPEVQRVLLQKLKDT GKPLIIVLAAGSSVNTECEGNALINAWYPGQYGGKALAEILFGEVSPSGKLPVTFYKSAD MLPDFTDYSMKNRTYRFCDDESNVLYPFGYGLTYSHFECGDISYKDNTLAVNVTNTGSRS AEDVLQVYIRSENGVKNHSLCAFERVSLFDGESRTISINIPEGAFETVDDNGVRAVRSGR YTLYAGFTQPTQLSEKLYGGRCVSVEISI > DME ID: DME1910 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MKRISIAFLSLFLCVASVWSMPRPEYPRPQFERAGWVNLNGEWTCSFDFGGSGMEREFYK SKGFDKKITVPFCPESKLSGIGYMDFINHFWYQRPITIPQEWNGKNILLNFGAVYYKSEV YIDGVLANRHFGGTSSFAVDITSLVKPGQTHSLVVYVESDVRGAKQAAGKQNLQYASYGC NYTRTTGIWQTVWMEAVHPEGLQSVQLLTDIDQQQLVVRPRFYKEAGGKLQVTLKDNGKV VASRTVSASSLSSVVLPVKKMKTWSPESPFLYDLEYKVLDKNGNIIDEVNGYAGMRKVHI EGNKIYLNNKPYYQRLVLDQGFYPDGIWTAPSDEALKRDIELSMEAGFNGARLHQKVFEE RFYYWADKMGYLTWGEASSWGMDCNDTETARNFITEWSEIVQRDRNHPSLLIWTPTNEEF WPDRVQYPRLMHDLYNLTKMIDPTRPFHGASGGTHIATDIWTVHNYEQDPAKLKEKLYNG GKLMEAPKWEIHLMPMNIGYNGLKYTDQYAFPEYKKDMPYLVDEFGGIKWNPSQQMESAQ NTSWGYGEPPRSLEEFYARLEGQVDAVLSLSNDIWGYCYTQLTDVEQEQNGIYYYDRTPK FDMKRIHAIFSKTPESK > DME ID: DME1911 DME Name: Sulfatase (sulF) PDB ID: Not Available MKKKVLFLILNYFAWLPLFVIQKPWFMTYNHPSAGNISLKDGWEVILHGLKLDCTVAGYL TVIPLLMTLISIWVTGKWYKKGIYAYTVMALLAITAIFSVDVALYAFWGFRIDSTLLFYL QSPKDALASIPARLFLQQTTSFLIYSTLGYLYLKRIIINHVPVEPVSNKVGATFAIIIVG AILFIPIRGGVTTSTANVGMVYFSQNQFLNHAAINPCFSLLSSLSKQEDFSKQFNFFDEK ERQDNIESLLSPVTSSDTTRILLKTRTPDILIIILESFSANVVEITGGLPDITPHLNQLG KEGVLFSHVYANSFRTDRGLVAILNGYPAQPTTSIMKYPAKSQTLPSIASSLRKAGYRSD MLYGGDINFTNMQSYFFSSGYSQITSDVDFPISDRLSKWGANDDVTFRFLLDHLKGREKE KAPWMTTFLTLSSHEPFEVPYHRFSHPYLNSVAFTDSCLGNFISRLKQSEIWDNLLIVLV ADHGFRYPEQLKDYEPDRFHIPMIWSGGAINKPAEINTICNQTDLAATLLGQLGISHQEY SFSKNILSPHRCDYSFYTFNNGFAFADSLGRYTIYDNESNRVLMEDAGNTMDRLQKGKAL LQTLYDDLGNR > DME ID: DME1916 DME Name: Methylthioribose kinase (mtnK) PDB ID: Not Available MSQYHTFTAHDAVAYAQQFAGIDNPSELVSAQEVGDGNLNLVFKVFDRQGVSRAIVKQAL PYVRCVGESWPLTLDRARLEAQTLVAHYQHSPQHTVKIHHFDPELAVMVMEDLSDHRIWR GELIANVYYPQAARQLGDYLAQVLFHTSDFYLHPHEKKAQVAQFINPAMCEITEDLFFND PYQIHERNNYPAELEADVAALRDDAQLKLAVAALKHRFFAHAEALLHGDIHSGSIFVAEG SLKAIDAEFGYFGPIGFDIGTAIGNLLLNYCGLPGQLGIRDAAAAREQRLNDIHQLWTTF AERFQALAAEKTRDAALAYPGYASAFLKKVWADAVGFCGSELIRRSVGLSHVADIDTIQD DAMRHECLRHAITLGRALIVLAERIDSVDELLARVRQYS > DME ID: DME1918 DME Name: Alcohol dehydrogenase (ADH) PDB ID: Not Available MKAAVIRDSVDGYVDIKDVTLRPITHGEALVKMEYCGLCHTDLHVAAGDFGKQPGRIIGH EGVGKVIQVADDVDNLKIGDRVSVAWFFKGCGHCEYCLTGRETLCRNVQNSGFTVDGAMA EECIVDANYAVKVPEGLDPIEATSLTCAGVTMYKALKVGETKPGQWVEVVGAGGLGNLAI QYAHNVFGAHVVAVDGNPDKLAAAKANGAEVLINRHDGNVAEQIQEKVGGVDNAQVTAVN KDAFTQSVNALKPDGKLVAVALPQGDMELNIAKTVLDGISVRGSLVGTRQDLAETFQFGA EGKVHPIVKTRRLDEVNDIIDEMKNNQIVGRMVVDFTK > DME ID: DME1919 DME Name: Sulfatase (sulF) PDB ID: Not Available MNMNDKKLIYRNPIYLIGTRFLKLYIIIGLILRIILMHATPGDASFSLGEIVRLLSIGIV SDFCMAILLALPLLIIYLGLNERKYHRIIGWMIEILLIASFVYVLFFHTIFHEYGGGAPT IARIFLGWKLFSFSMRFFFPKIRETWRRVSLYLTWAVYVFLFLCVTAGEYIFWGEFGVRY NFIAVDYLVYTHEVIGNIMESYAIIPMIGMTLLLTVGIIFLQSRHYRFNITKLYGVKMLI IHLFLYAVLATSAYFILWETHSLKSDNQYVTQLEQNGACDFVIAFQSNKLAYDQFYAMLP KQECISMYRQLSGLNKDGKKNIGDSLAENRPNIVLITVESLSADFLTRYGNKQNLTPRLD RLMQESLVFDSLFAAGNRTVRGLEALSLCLPPSAGESIIKRKANRMGNLSVGSVLSRLGY KSQFIYGGDSYFDNMGDFFSHNGYEVIDRKNIPDNQVTFANIWGVCDEDIFRKSLQVFDT NNKSGHPFFAQIMTTSNHRPYTYPAGKITVNGDPNTREASVKYTDYAIGKFIDDAKKKVW FKNTVFIVIADHCASSAGKTSLPIDRYHIPCLVYAPEIIQQEKIEKICSQIDLMPTVLSL LNLRSSVSFTGQDILAPTYHPRAFMATYQDLGYMEDNRLTVLSPVRNVQQYTLRPLQDGT YDEQLARKTDEKLVRKAQAYYQYTNLYVKAK > DME ID: DME1921 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKLKRLVFLIPIWLIALCSFGQAGHVSARLTLDGKMQALAERLLEGKQGSIVAIEPSTGE VKCLVSKSFLSDTINRAIGQAYSPGSTFKVAQALALVSEGIVNKDSKFTCSEGFWKNNMH IGCHKHSSPQDLIGAIAHSCNSWFCKAFMNMIRDRVKYKNKLEAINKWKEYMSSLGLGRP LGIDMEGETDGEMPDSEMLERLYSGRWNEATIMWVGMGQGEVLATPLQLCNLAAIIANKG YYYIPHIHKDVDTTYTTRRLSTASPEAFELIRKGMRKAVTTGTATAIQHPDWQICGKTGT AENPGEDHSVFIGYAPMNNPKIAVSVYVENAGFGADLAAPLAQLMIEQYLTGKLSERSER KARQWYDFLVVPHDPTEVTEKETPTKIPMPTQPASPSTSPKGKS > DME ID: DME1923 DME Name: Glycerol/diol dehydratase (dhaB) PDB ID: Not Available RYAPFNAISILIGAQTGRPGVLTQCSVEEATELQLGMRGFTAYAETISVYGTDRVFTDGD DTPWSKGFLASCYASRGLKMRFTSGAGSEVLMGYPEGKSMLYLEARCILLTKASGVQGLQ NGAVSCIEIPGAVPNGIREVLGENLLCMMCDIEC > DME ID: DME1929 DME Name: Alpha-L-rhamnosidase (lrA) PDB ID: Not Available MPNITPSLLAPDHLRVNLQHFAYNIQAQPHFSWWNHSNRTGASQSAYQLTVFQRLQDRQN HNYLYDSGWVTSSNNTAVTAAKLSDQLVPGQLYYWQVRIKDNAGSISDFSQPAKLICADP SLPVKHGIWRQPQPKTAQELAHIGQVVFLRSPQLKINLSEVDTAVIVAVARGNEPVFAQS FDLYLNGHCLGVGSARQQEHDHGTEKTAIYYNVYEATDFLQDGANTVAALATASSDRQAF WCQLILYKHDGTKEVATTTDNTWRALDGSSAFGDYGVKIRTQYFGMVSENIDMRYYPQNW TDSAFDDHDWPLAWQNPYQLIADNEVLVPFRSENTERVEVHDRNKRVVTFSDQNYLLDLG KEIIGGLKVNLFSAFDQRVTVMMGEQLNDDGHVRHEMACGPDYIENWTLVKGQNQFTTLQ MKNFRYVELVGFEGDLPLDAINGWAMQQAFPDNESQFDSDSELLNREYELSKYTIKATNQ DVFVDSQARERRPYEGDLLVNANTSYSVSSNYSLARHSLDYLIDNPTWPEDYKLFAIEMA WLDYLYTGDDDLLQTRYTDLQYKLNRGKSAESFDGASQSFTGSLKNSQGVDNFDAAVGLV TNDGLVDWPISERDGFVEGTYNTPFNAIFHGAYATMAKIARVLHHPDDADRYQKRAEIIK TNLIDKLYDPQTGRFFDSLNADLSVNRHTSHHASAYALCYGVYTDQNMADRLSHFVANDG HFVGSIYFIYFMLKGLFEAGHAADAITLLTDPDNHKDHKSFAAILDSLKATIAPEAWSNA YKPNLTLSHPWGATPGLTIVQGVFGIVPLAPGFATFRVKVRPGNLKHLDLTTPSVKGLIT LHYRHEPTHQTLDVTVPMNTTAKVELPDDAQAIVVHDQYGKDWTASIEHDHDTLTIPMGR YQIQYQA > DME ID: DME1933 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MFPKDFVWGVASSAYQMEGTDPDDGRGKNVWDEFVRSGRVYEQQTADVSCDHMHRYKEDF ALMRLLGIKNYRFSLSWSRILPAGTGKVNEKAVQMYRDMILCMKENGIRPFITMFHWEFP YELFKKGGWLNEDVVEWFGEYAKVVAENFSDLCTDFITINEPQCAIGLGHLSGVHAPGMQ YSVPETFQMAHNLMKAHGQAVINLRKYAKQKIRVGYAPTCGVAYPASEGTKDIEAAKKVY FGFDNPMDNWTWNVAWFSDPVFLGEYPKEGLEKFAPYLPEITKEDMELIHQPLDFMGQNI YNGYMIRCGKDGKPEYVDRAPGAAKTGTGWPVTPEALYYGIRFLTERYHLPLYITENGMS DLDNISADGQVHDSERITFLDAYLGAVQRAVNEGVPVIGYFLWTFLDNFEWAEGYKERFG LVYVDYTTQRRIAKDSAYWYREVMKMNGENLSCNQPCKEILFMNPVFTHNIWGGTKLREE FGYAIEGDDIGECWGIAAHPNGTCTIADGAYKGKKLSDLWEEHKELFGNTQGKVFPLLIK IIDAKADLSIQVHPDDTYAAEHENGSLGKMECWYILDCEPDSKLVIGHNAKTHEELEDMV HNGRWSELIREVPVKKGDFIQIDPGTVHAIKGGITILETQQNSDITYRVYDYDRLSNGKP RQLHIQQSLDVIKVPAAPLSECMIKTGEAEANKLQKLIECKYYQVFHMKVEGQAEFEQEY PFLIVSVVEGNGLLNHTSVKKGDHFILPYGYGKVEIEGNLEFVASTVSTK > DME ID: DME1934 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MFREDFVWGVASSAYQVEGTDAADGRGACVWDMFAADGRVFEHQNADTSCDHMHHYKEDI ALMKHLGIRAYRFSLNWARILPEGTGRVNEKAIAMYRDMILTMKENGITPYLTLFHWEFP QALYERGGWQNPDVVQWFGEYAKVVAENFSDICEYFITINEPQCVVGLGHLSGVHAPGVK LPVAQTFLVAHHLLMAHGQAVINLRRYAVRPVKIGFAPTGGVAYPYTDRPEDIEAAKKVY FGFYNPIDNWTWNVSWFSDPVFLGHYPEEGLKKFAPYLPEITQEDMELIYQPLDFMGQNI YNGYYVRAGADGEPEFVDRAPGFPKTGSDWPVTPEAFYYGIKFLTERYPLPLYITENGMS CHDMVSSDGRVHDPNRITFLDSYIGAMQKAYDEGANVAGYFLWTFLDNFEWADGYKQRFG IVYVDFASQRRIVKDSAFWYQKIIETNGRMLTMNQTTKEILFLDPVCTHNIWGGTRLRTE FGYPVEGDDIGECWGISAHPNGDGSIRNGVYAGMKLSKVWEEHPEVFGNLAYDRFPLLTK IIDAKADLSIQVHPDDAYAKEHENGSFGKTECWYIMDAPENATLVIGHNAKTKEELASMI HEGRWSEFIREIPVKKGDFIQIDPGTVHAIKGGLLILETQQNSDITYRVYDYDRLQNGRP RELHIEKSIDVITVPAKSVEDSVTSALGLPENRLNELYACGYYQIYKLDVNGTCSFAQNH PFLLMSVLEGSGIVNGQPVKKGDHFILPCGFGEVEMQGEMSLVVSTVPA > DME ID: DME1935 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MLYPRENSVRGVIDLGGVWNFKLGDEKEPGDSFAMGEDTELMAVPASYNDQKDDPKYRNH YGWAYYERKITVPSYLKGQRLVLRFDAVTHAAKVYLNGRFLTAHKGGFLPFEVDVTDQLV PGETAELVVAADNRVNHSTLPVGNEGSTAFFGSDNPGVPSVEAAKVWRKPQNLPNFDFFN YAGINRPVRIYTTPAAYIEDITLVPDIDGDTGVVNYEIKTAGSVCEDEVRIRILDADGNE VAAADGAGGTVRIPDARLWWPWPGEPYLYTASVTYGEDLYEETFGIRTVAVEGTQFLING KPFYFKGFGKHEDAAFRGRGLDVCLDVKDINLIHWLNANSFRTSHYPYAEEMYQLCDREG IVVIDETPAVGIGAGDKIDPYKTFHIREHHEQVLREMIARDKNHPCVVMWSMGNEPDTEH FPESAYDYWHSLYELTHSIDPADRPVTFVCCQNNYERDLVTRTMDVVCVNRYYGWYNLSG DLDAACYALNMELDFWEKQNKPVMITEYGADAVAGIHESVPEMFSEEFQKEYYRRQNAEF DKRSFFIGEQVWNFADFATIQGCMRADGNKKGLFTRDRRPKMAAHYFKERWGQIPNFEYK > DME ID: DME1936 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MFRDDFVWGVASSSYQVEGTDANDGRGKTVWDAFTEAGRIFENQNAYTTCDHMHHYKEDY ALMKNLGIKAYRFSLNWARILPEGTGRVNEKAIRMYRDMITCMKENGITPYITMFHWEFP QALYEKGGWLNPEVADWFGEYAKVVAERFSDICEYFITINEPQCVVGLGHLSGVHAPGVK MSIKDTFQIAHNLMKAHGQAVINLRKYAVRDIKVGYAPTGGVAYPYTDKPEDIEAAKKVY FGFYNPMDNWTWNVAWFSDPVFLGHYPKEGLEKFAQYLPEITEEDMKLIHQPLDFMGQNI YNGYYVRAGENGEPEFVDREPGFPKTGADWPVTPEAFYYGIKFLTERYPLPLYITENGMS CHDNISADGRVHDPNRITFLDSYIGAMQRASDEGADVRGYFLWTFLDNFEWSDGYKQRFG IIYVDFTTQQRIVKDSAFWYQKVIETNGGILSMNQANKDILFLDPVCTHNIWGGTKLREE FGYPVEGDDIGECWGISAHPNGDGTVRSGAFSGMKLSAVWKEHPEVFGNYDCDRFPLLTK IIDARDDLSIQVHPNDDYAKVHENGSFGKTECWYIMDAPEGATLVIGHNAKTKEELSDMI HQGRWKEFIREIPVKKGDFIQIDPGTVHAIKGGLLILETQQNSDITYRVYDYDRLSNGKP RELHVEKSIDVITVPAKSVDDSVKSALNLPENQLNELYSCKYYTIFKADVNGKMEFEQKY PFLLVSVLEGDGIVGSSPVKKGDHFILPNGYGKVEMQGKMSLIVSTVK > DME ID: DME1937 DME Name: Beta-glucuronidase (uidA) PDB ID: Not Available MLYPQENKIRGIIDLNGVWDFALGTTEEPGDAVTLPEQMEPIAVPASYNDQKDDIAYRNH YGYAYYRRNITVPSYYKGQRLVLRFDAVTHFAKIYLNGVLLTQHKGGFLPFEVDITDKLC AGESAELVVAVDNRINHSTLPVGNEEGTSFMGADNVGVPGVEAAKRWRKPQNLPNFDFFN YAGINRPVRIYTTPKAYIKDVTLVTDIRGTDGIVNYQVKTSDTDGQEVVLQILDANGNEV AQAKGTSGEIVIPDAKLWEPYPGTPYLYTAAVTFGDDYYEEPFGVRTVRVEGTSFLINGK PFYFKGFGKHEDSAFHGRGMDVCLDVKDVNLIHWLHANSFRTSHYPYAEEMYRLCDREGI VIIDEVPAVGIGAGAGINPYETFPIREHHEQVIKDMIARDKNHPCVVMWSLGNEPDTENF PESAYKYWHSLYELAHETDPSNRPVTLVCCQNNYEKDMVTRSMDVVCINRYYGWYNLSGD LDAACYGLNLELDFWEKQNKPVMITEYGADAVAGIHECVPEMFSEEFQVEFYKRQNAQFD KRKFFIGEHVWNFADFATVQGCMRVDGNKKGLFTRERRPKMAAHYFRERWGEVPDFGYKR > DME ID: DME1938 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MFDDKFVWGVASSAYQVEGTDPDDGRGKTVWDTFTEQGRIFQNQNAYTSCDHMHHYKDDY ALMKNLGIKAYRFSLNWARILPEGTGRVNEKAIAMYRDMILTMKENGITPYITLFHWEFP QALQEKGGWLNEEVVDWFGEYAKVVAENFSDLCEYFITINEPQCVVGLGHLSGVHAPGLK LSIPETFQIAHNLLKAHGQAVINLRKYAKQKIRIGFAPTGGVAYPYTDSAEDIEAARKVY FGFYNPMDNWTWNISWFSDPVFLGHYPKEGLEKFKEYLPEITETDMQLIHQPLDFMGQNI YNGYYVRQGADGEPEFVDREPGFPKTACNWPVTPKAFYYGIKFLTERYQLPLYITENGMS CHDNVSFDGRVHDNDRITFLDSYIGAMQRAYDEGVDIRGYFQWTFLDNFEWSEGYKERFG MIYVDFMTQRRIVKDSAFWYQDVIKTNGGNLSMNQTTKEILFLDPVCTHNIWGGTRLRED FHYPVEGDDLGECWGISAHPNGDGTLRDCGFSGMKLSELWKKHPEVFGNVDSDRFPLLIK IIDAKDDLSIQVHPDDDYAKVHENGSLGKTECWYILDCKENATIVIGHNAGTKEELSRMI HEGKWSEFIREIPIKKGDFLQIDPGTVHAIKGGTLILETQQNSDITYRVYDYGRLSNGKP RELHIDKSIDVITVPAKSVADSVKSVADLPVNTLNELYVCKYFHIYKIEVSGKMTFEQNA PFMNMTVTEGNGIVNGQPVKKGDHFILPNGFGNVELQGRMQIIASTI > DME ID: DME1939 DME Name: Beta-fructofuranosidase (BFRU) PDB ID: Not Available MSNMLEKARKYETEKIAATDPQTKPLFHVSAPTGWINDPNGFSFYDGQIHLFYQYHPYNR EWGPMHWGHSVTCDMIHWEQLPAALAPDEEYDKAGCFSGSAIEADGKHVLVYTGVTRIKQ PDGSEQDRQNQCIAFGDGKDYQKYDKNPVMTGEMLPEGCNRVDFRDPKIWKENDTYYMIV GNKNENQIGQVVLCSSKNLTDWKFETILASNESGKIGTMWECPDFFQLGSKRVLICSPQD MKAQKYEFHNGHNSVYFLGDYDEKTHTFVKELPHALDYGMDFYAPQTTELPDGRRIMIAW MKSWDACVIPNSQDWQGMMTLPRELELKDGKIWQTPVREIEKYHKNPCRYDHAEINQETT LCGIEGRTIDLTVLLEEDEFQTFSMKLAANKEYETSFTYHKAENMLEIDRTYCGVTKDVV CVRKLKISNPEGLKKMRFILDRQSIELFLNDGEQVATTAICTPLEAQEIHFYSDKKIHIN VEKYDIMSASEKNAFMHSANDEIIE > DME ID: DME1940 DME Name: Beta-glucuronidase (uidA) PDB ID: 5Z18; 5Z19 MLEYSELYPIQNEYRMMQSLDGMWKFQFDPEEIGKKSGWENGLPAPVSMPVPSSFADFFT DHKERDYCGDFWYETEFYLPAEWRNKKIWLRFGSITHRGTVYCNGMEITSHEGGFLPVLA DISTVAKPGQVNQVVVKINNELNETSLPCGATKILNNGRKLAKPYFDFFNYSGLQRSVWV IALPEESVKDYSVDYELCGTDALVKYEVVTTGEHPVIVRLLDAEGELVAETEGKEGILQV ANARLWEVRNAYLYQIVILITDGNGVLDEYREKIGIRTVRIEGTKILLNDRPVYLKGFGK HEDFPILGRGFHWGIVKRDFECLKWTNANCFRTSHYPYAEEWYQFADEEGFLIIDEVPAV GMMRSTRNFVAAGSGNYTYFFEALTVPELLKSHIADTEEMITRDKNHPSVIAWSLFNEPE TITDYAYEYFKEVFAAAETYDFQSRPMTGAFEKNSKPELCKCYPLCDFICLNRYYGWYIS GGPEIEEAEELFRDEMDRWKAKELNVPFVFTEFGTDTMAGLHKLPSIMWSEEYQKEYLEM NFRVFDSYEFVQGELAWNFADFQTTEGIMRVDGNHKGVFTRDRQPKAAAVVFKDRWEKKN ELF > DME ID: DME1946 DME Name: Azoreductase (azoR) PDB ID: Not Available MSKVLVLKSSILAGYSQSNQLSDYLVEQWREKHSADEITVRDLAANPIPVLDGELVGALR PSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFR YTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYG PEMAAKAQSDAKAAIDSIVAA > DME ID: DME1949 DME Name: Arginine dihydrolase (arcA) PDB ID: Not Available MTQGPIQVNSEIGKLKTVLLKRPGKELENLVPDHLSGLLFDDIPYLKVAQEEHDKFAQTL RDEGVEVVYLEKLAAEAIADKAVREQFIDDILAESQKTILGHEEEIKKFFETLSDQELID KIMAGVRKEEIELETTHLVEYLDDRYPFYLDPMPNLYFTRDPQASVGRGMTINRMYWRAR RRESLFITYILKHHPRFKDADVPVWLDRNSPFNIEGGDELILSKEALAIGISERTSAQAI ERLARNIFKDESTTFKKVIAIEIPNSRSFMHLDTVFTMIDYDKFTVHSAIFKEENNMNIF TIEYDEAKDDIKITHSHKLRETLADVLGVDHIDFIPTGNGDVIDGAREQWNDGSNTLCIR PGVVVTYDRNYVSNQLLRDKGIKVIEITGSELVRGRGGPRCMSQPLFREDI > DME ID: DME1953 DME Name: Glutamate racemase (MurI) PDB ID: Not Available MDNRPIGFLDSGVGGLTVVRELMRQLPHEEVIYIGDSARAPYGPRPAKQIKTYTWELVNF LLTKKVKMIVFACNTATAVVWEEVKEKLDIPVLGVILPGSSAAIKSTISGQIGIIGTPMT IKSNIYEQKIRDLSPQMKVRSLACPKFVPIVESNKMNSSVAKKIVYESLSPLVGKIDTLV LGCTHYPLLRPIIQNVMGPDVELIDSGAECVRDISVLLNYFDLNRSRTSKVLHHRFYTTA SVASFKEIASDWLPLAIEVEHVTL > DME ID: DME1957 DME Name: Methylenetetrahydrofolate reductase (metF) PDB ID: Not Available MVRRHTPSLSFEVFPPNPAVGNDKIFQALREMQDLAPHFISVTASNNKFDIEETTVRLTE FIANELQIPTIAHLPAVYLTKDMVSNILQSLDRVGVHQILALRGDIFPDVAPKDDFTYAT DLIEYIKTEAPHFDIIGACYPEGHPDSPNQISDIQNLKKKVDAGCSSLVTQLFFDNERFY DFQDKCILAGIEVPIHAGIMPILNRNQALRLLKTCENIKLPRKFRAILDKYEHDPESLRA AGLAYAVDQIVDLVTQDVAGIHLYTMNNAATAYHIYKATHALFNHNPSVQSF > DME ID: DME1958 DME Name: Nitroreductase (NTR) PDB ID: Not Available MESIKNRTSIRKYAEKEVSEELLNRLLEEAERTPTMGNLQLYSVVVTRSEEGKKALAPAH FNQPMVTGAPVVLTICADYRRTTLWAENRKGTPGYDNILSFMNAATDALLFTQTFTNLAE EAGLGTCFLGTTVYMPKMIIDTLKLPKLVMPVATLTIGWPAEHPALSDRLPLRSIIHHEH FEDYTPEKIDDFYAEKEALEENKEFVRINNVETLAQVFTDIRYTKKDCEAMSQGFLEALK QQGFI > DME ID: DME1967 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MPTENYKFPADFVWGAATSSYQIEGAVSEDGKGEDIWDVFTKEDHRIFEHHTGETACDHY HRFKEDVKLMKEIGLHAYRFSINWSRVLPNGYGQVNEKGIAFYNALINELLANDIEPYIT LYHWELPYELYKRGGWLNPQIVDWFGDYARLIAERFSDRVKNFFILNEPQCFVGLGFLTG EHAPGVQAPLRDTFEMAHNALKAHGKAVQMLRAYGKQKLSIGFAPTASMCYPETESAEDI EAARKALFSLPDDPHNWTWNVSWWSDPVFFGKYPEEGLQKYEKYLPKITDDDMKLISEPI DIYGQNIYNGQCIRMGKDGHPEYVRRYEGFPKTAIDWPVTPECLNWGPRFLYERYKTPIY ITENGMSCHDVVSLDGKVHDPNRIDFLARYLDELKKAATVADIRGYFQWSLMDNFEWSKG YSERFGLIYIDYQTQQRILKDSAYWYKDYIKNNGEF > DME ID: DME1968 DME Name: Nitroreductase (NTR) PDB ID: Not Available MKKGARMSETLNVVTLLGSLRKGSFNGMVARTLPKVAPAGMTVSPLPSIGDIPLYDADIQ QEEGFPASVEALAEQIRNADGVVIVTPEYNYSVPGGLKNAIDWLSRLPEQPLAGKPVLIQ TSSMGAIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQTGEVVDQGTLDHLTG QLTAFGEFIQRVKA > DME ID: DME1971 DME Name: Oxygen-insensitive NADPH nitroreductase A (nfsA) PDB ID: Not Available MSPTIELLCGHRSIRHFTDEPVTDAQREAIIAAARSTSSSSFLQCSSIIRITDRALREAL VPLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLLLGVVDTAMMGQNALTAAE SLGLGGVYIGGIRNNIESVTELLKLPKHVLPLFGLCLGWPADNPDLKPRLPAELVVHENQ YQPLDEKLLARYDEQLAEYYLTRGSNTRRDTWSDHIRRTLIKENRPFILEYLHKQGWATR > DME ID: DME2014 DME Name: Insulin-degrading enzyme (ide) PDB ID: Not Available MSDPLYSIFFKPSTIKAMKINYLIITLGCIGSLLGFPLLPALENKGYTLIEDKALLKVKT PTFSQTQVLKIKLNNGLQAVLISDPQTDQSSATLVVGAGSWQDPDPYPGLAHFVEHMLFL GTKKYPNESEFQRFITEHGGFSNAFTANDHTAYMFSIDNEAFPQALDRFASFFKEPLFNV SGIVRELNAIDQEYAKNYENDDVREVMVMKHIQNPRHPNYRFNIGNSTTLKAASQEILKA WYNEHYSSNIMRLLLVSNLPLEEMTRLTVDEFGDVADKHKVCYVPPMDLNNPDMEAKLFY ITPIQNIRKLTLVWDLPQEFAEMKDTYPDRLICQVLGHEGKESLLAQLKREKLAENLGCS TFNLGEKNLVLFVQMELTDKGVQSIDRIILRCFQTLALMKEKPFPRYIYDEVRQINLLNY EYQQREEVFTAAMKNADLLVRENIATYPEQTKVIQKFSQADVQNLLDYLTPSNCRFLIQA PSSLTGVEPTHQEEWLQVAYAMKAIEPFKMQEWASATPIAEITLPLPNPFLPKSLDLLHA LPSKETHLSRLPHPHLIEDSEHGTIYYAKDQHFLIPQLYLNFNIRTPAIDIGDANKIVMG DIYIKAVEENLSKFSYAATVAGLNFSVARTEYGLAFKITGYNDHAFLLFEEILKQLKDLK LSEQAFKIIKQSLLRRYQNFNKRAPLKRAKELFQQTIYKKYAAEHQKISAIRKLSFAKFQ EDVQSLFRQSFVEGLIYGNVTENQAKEYADNLIKTLDSAPYPKQMHKHAEIINLSSAEGP LLLEMKIPVQGSATLLAIENSSFTLKERAAQQILMKAMKEPFFAELRTRQQTGYLISSAA EEIERKLFLAFVVQSNTHDPRDLLARFELFIESFLQGIEKNYLTLKNFEIIKNSLLEELE KPPHNMESLGALLHSLAFKYEGRFDWIDKRIQALRALTHGELLSFTHACIGKDNKRRLGL LIKGHMDKAKGLYYTLINTPEQLKQKSTFSSSWGNEEKERKLE > DME ID: DME2021 DME Name: Carbapenemase (cphA) PDB ID: Not Available MLTRRTFIASAVLAGWIPALAHARTDKKTRWTRESLAAFQQGLAQVEAASRGRLGVALLD VGSGQAAGYRADERFLMLSSFKTLSAAYVLARADRGEDQLSRRIPITDADVREYSPVTRL HVGPRGMTLAELCEATITTSDNAAVNLMHKSYGGPQALTRYLRSLGDTVTRHDRYEPELN RPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQQLQSWLLANTTGGKRLRAGMPADWK IGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLETTAVPMEERDRCIAEVGRLVAALG > DME ID: DME2023 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MNTRYLKIFSALVVIAIIFVARLSYLQLFTDRYALNAANTSIKIEYVIPQRGVVFDRNGK ILVGNQPAYEISFTQALMKPDFDTIGFCNLMQISKSDFIKRIEIIKKEKYYSKLTPMTFI KDLSREDIARVQEIIFKYPAFSIVSRPQRQYEVATSGNLLGYTSEVNEREIKKDSTYYLP GDFIGKTGVEKSYEKDLRGIKGMKYIQKDIKLRNIGSYKNGSLDKDVVTGKDITLTIDYD LQRIAEEMLVNKHGAIVAIDPNNGEILTLATGPDIDPNLFTGPNKSKNLYALSKDTLYEN KPTFDRSVQAAYPPGSTFKLLTALAGMQMGVMDENTVFPCGGGFFYKGLRIKGHGGADPL IPAIQVSSNCYFSHAFIAIMNKYPGDPSRGVNEWKKIMSSFGVGEYLNNDIAVGSPGRIP TGEFYEKRSGKKNWSSDYTMNGSIFNGMGQGDVLVTPLQLANYVAAIANKGWFYTPHIVK SIDGKPNPDPRFKTKHKTLVDPKHFEPVLKGMEAVVLRGTARSLKSSDFTQLAKTGTAQV PQGKDNSIFVLIAPADKPRIVVAAVMEHAGFGATWAGPACTVIAEKYITGDLKRENLYKK MTGASFMPEYKRQWIADLKRKGLYKDPTADSLKLKRKQDSLNFIKEQKAKLQKKIEEETK NNTKKIKK > DME ID: DME2024 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MMKKSICCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAIPGMAVAIIYQGKPYY FTWGKADIANNRPVTQQTLFELGSVSKTFNGVLGGDAIARGEIKLSDPVTHYWPELTGKQ WQGISLLHLATYTAGGLPLQVPDDVTDKAALLRFYQNWQPQWAPGAKRLYANSSIGLFGA LAVNPSGMSYEEAMTKRVLRPLKLAHTWITVPQSEQKDYAWGYREGKPVHVSPGQLDAEA YGVKSSVIDMTRWVQANMDASQVQEKTLQQGIELAQSRYWRIGDMYQGLGWEMLNWPVKA DSIISGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTGGFGSYVAFVPEKNLGIVMLA NKSYPNPVRVEAAWRILEKLQ > DME ID: DME2025 DME Name: Carbapenemase (cphA) PDB ID: Not Available MMKKSLCCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAIPGMAVAVIYQGKPYY FTWGKADIANNRPITQNTLFELGSVSKTFNGVLGGDAIARGEIKLSDPVTRYWPELTGKQ WQNISLLHLATYTAGGLPLQIPNEVTNKTALLRFYQNWQPQWAPGAKRLYANSSIGLFGV LAVKPSGMSYEEAMIRRVLQPLKLTHTWITVPQSEQRDYAWGYRDGKPVHVSPGQLDAEA YGVKSSIMDMARWVQANMDASHVQEKTLQQGIGLAQSRYWRIGEMYQGLGWEMLNWPVKA DTIINGSDSKIALAALPAVEVNPPAPAVKASWVHKTGSTGGFGSYVAFIPEKNLGIVMLA NKSYPNPARVDAAWRILEKLQ > DME ID: DME2026 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCFLLYDASTNAEIAQFNK AKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVV WVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAWLESSLKISPEEQIQFLR KIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTANRTLQNGWFEGFIISKSG HKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL > DME ID: DME2027 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKLFVLCVCFLCSITAAGATLPDLKIEKLEEGVYVHTSFEEVNGWGVVSKHGLVVLVNT DAYLIDTPFTATDTEKLVNWFVERGYKIKGTISSHFHSDSTGGIEWLNSQSIPTYASELT NELLKKDGKVQAKNSFSGVSYWLVKNKIEVFYPGPGHTQDNVVVWLPEKKILFGGCFVKP DGLGNLGDANLEAWPKSAKILMSKYGKAKLVVSSHSEIGDASLLKRTWEQAVKGLNESKK PSQPSN > DME ID: DME2028 DME Name: Carbapenemase (cphA) PDB ID: Not Available MLAVKIKPFTKPILIMKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCFL LYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGMEIW NSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAWLE SSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTANRT LQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL > DME ID: DME2029 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPATKYWPELTAKQWNGI TLLHLATYTAGGLPLQMPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK STIEDMARWVQSNLTPLDINEKTLQQGIQLAQSRYWQIGDMYQGLGWEMLDWPVNPDSII NGSDNKIALAARPVKAIKPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY PNPARVAAACQILNALQ > DME ID: DME2031 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKLLFLLALMVASPLSHASKLHEDVSLLEQQISGRIGIAVWDTQTDKHWAYRGDERFPL VGTFKTLACATMLSEMDTGILKKNATATVEKRDMVMWSPIMDKLAGQNVRIEHACEAAML MNDNTATNLVLSEIGGPKSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVN TLETLIDGDALSYESRIQLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAI IWKENHKPVYISIYLAETELSLQAREQLIAQISQLILYKYRNI > DME ID: DME2039 DME Name: Acetone carboxylase (ACX) PDB ID: Not Available MAYTKAKIKDLVDGKIDRDTLHTMLATPKDADRFVMYLEVLQDQVPWEDRIILPLGPKLY IVQRKSDHKWVVKSHAGHEFCDWRENWKLHAVMRVRETPEAMEEIYPRLMAPTAGWQVIR EYYCPLSGDLLDVEAPTPWYPVIHDFEPDIDAFYSEWLGLKIPERAA > DME ID: DME2040 DME Name: Acetone carboxylase (ACX) PDB ID: 5M45; 5SVB; 5SVC MNVTVDQSTLAGATRGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKL FSRLRAGVVDARETAKKIAASPIVEQEGELCFTLYNAAGDSLLTSTGIIIHVGTMGAAIK YMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPIFWEGELIGWVGGVTHVIDTG AVGPGSMATGQVQRFGDGYSITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRLGLQARIKAMTIPGTYRQVGFVDVPYAH EDVRVPSDFAKLDTIMHAPCEMTIRRDGTWRLDFEGSSRWGWHTYNAHQVSFTSGIWVMM TQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYSWHFLVSAWTALWRGLSRSYF GRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVQDGLSHAAAIWN PEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKYRGGCGFESLRMVWNAKDWTMFFMGNG HISSDWGLMGGYPAASGYRFAAHKTNLKELIASGAEIPLGGDTDPENPTWDAMLPDAQIK RDKQAITTEEMFSDYDLYLNYMRGGPGFGDPLDREPQAVADDINGGYVLERFAGEVYGVV VRKGADGQYGVDEAGTAAARAQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQVRQMFAA SFKLGPRFEKDFRTFWSLPDSWTLPEEEIGVPTYGSRYSMDISELPDVHTVQFVEE > DME ID: DME2046 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MNPRHLKILSILIIIAVIFIARLSYLQLFTDRYALNAANTSIKTEYVIPQRGVIFDRNGK ILVGNQPAYEISFTQALMKPDFDTAAFCNLMKITEKDFINRINKIKTEKYYSKLTPMTFL KDLSREDIARVQEIIFKYPAFSIVQRPQRQYEVSTSGNLLGYTSEVNDREIRKDSTYYLP GDLIGKAGVEKSYEKELRGIKGIKYIQKDIKLRSVGPYKNGTLDRDVVTGKDITLTIDYD LQRMAEEMLVNKHGAIVALDPNNGEVLVAATGPDIDPNLFTGPNKSKNLYALSKDTIYEN KPTFDRSLQAAYPPGSTFKLLTALAAMQMGLMDEKTIFPCGGGFYYKGKRIKGHGGADPL IPSIQVSSNCFFTYAFIKIIKKYPGNPSRGVDEWKKIMSSFGVGEFLNNDFAVGAKGRIP SGDFYERRFKAIMKASGSKRQDFKDWDEMSTGAIYNGMGQGDVLVTPIQLANYVAAIANK GWYYTPHIVKSIDGKPNPDPRFKKKHQTLVDKKHFDPVLKGMEAVVLAGTARGLKSNDFT QLAKTGTAQVPQGKDNSIFVLIAPADKPKIVVVAVMEHAGFGATWAGPASTVIAEKYITG DLKREHLYKKMVTSSFMPEYKRQWIADLKRKGLYKEPKPDSLKLKKIQDSLNQAKKKKEA LQKKLQLESSKTKKQ > DME ID: DME2057 DME Name: Aminoglycoside 6'-N-acetyltransferase (aacA) PDB ID: Not Available MTEHDLAMLYEWLNRSHIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPI GYAQSYVALGSGDGWWEEETDPGVRGIDQSLANASQLGKGLGTKLVRALVELLFNDPEVT KIQTDPSPSNLRAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSDA > DME ID: DME2059 DME Name: Beta-galactosidase (bgaB) PDB ID: Not Available MTENPTTTAFNELQTRPLATILARNDWQNPAITSVNRLPSHTPLHGWRDADRARRGEPSD AVLSLDGEWQFSFFASPHQVPEVWLAADLSDARATPVPSNWQMEGYDTPIYTNVRYPIPV NPPFVPDDNPTGCYSRDIEVPQAWLETGRTRIIFGGVNSAFYLWCNGQWVGYSQDSRLPA EFDLTGVLHAGRNRLCVLVLRWSDGTYLEDQDMWRMSGIFRPVSLLHLPEQALADVRVHT ELAPSLRHATLFSEVEVTPAACGLSVTLALWHGENEIASQTLPLGSAPIDERGNYAERVT LSLDVDNPLLWSAETPHLYRAVVTLLDADGMPLVSEAHDVGFRRVEINNGLLTLNGQPLL IRGVNRHEHHPEKGQAVDEAAMVQDILLMKQNNFNAVRCSHYPNQPRWYELCSRYGLYVV DEANIETHGMEPMSRLSDDPVWLGAYSERVTRMVKCNRNHPSIIIWSLGNESGNGATHTA LYNWIKHQDPTRPVQYEGGGADTRATDIICPMYARVETDQLIPAVPKWSIKKWISMPGET RPLILCEYAHAMGNSLGNFADYWAAFRQYPRLQGGFIWDWADQAITRVEPDGSRWWAYGG DFGDTPNDRQFCMNGLVFPDRTPHPALFEAKHQQQFFQFRLVSENPLQIEVTSEYLFRES DNERLLWSIEVRGETRLSGELTLELGPQASRVLTLSDTGFSARAGDEEIWLHVRVEQPQA TPWSPEGHLSAWAQWPLAAPLALPEPVAAGDAPQLEITDAEFVIRHGCQTWRVSRASGQL IQWSDDGVDQILTPLADQFIRAPIDNDIGVSEVERIDPNAWVERWKAAGLYNTEHRCLAC DAQTTRDGVEIVAQHAYFVKGVADGPAILSRWRMVVDNQGALHCDIDIARSAALPPLPRV GVVCQLRGGEETASWLGLGPHENYPDRLSSACFSRWTLPLSELTTPYIFPGENGLRCNTR ELNWNGWQAEGEFHFSLSPYGTRQLMETSHWHKLQPEAGIWLTIDGFHMGVGGDDSWTPS VHPEYLLTAREYRYRFTLRRRQG > DME ID: DME2060 DME Name: Beta-glucosidase (bglA) PDB ID: Not Available MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQHPSIQWNEEKKIWEIA LDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWARIFPRGDEQKPNEAGLVFY DRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLIDFFEFYAQTVFERYQGKVKY WMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKKVIYQACHHMFLANARATQLLKK IDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKRNSWFFSDVMCRGHYPAYIYRTWKE EDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYKKEAEMRVDTGGANGFDNPFLKEKSPE PWSWPIDPLGFRYVMNELTDRYELPLFIVENGIGLDEAPDELNRIHDPKRCEYLKIHLQE IAEAIKDGCQIIGYLWWGPIDIVSAGTGEMRKRYGFIYVDRQNDGSGSFRRLKKDSFEYY KQIIQSNGKNLEYRSFFK > DME ID: DME2062 DME Name: Glycosyl hydrolase (glyH) PDB ID: Not Available MKHFKQAVSLMALGVMQASGALAAGPATGNEVEARVSSILDNMNQAEKINFTRVNDGHMI PSLLKWGIQGTVAYDSSMGVHVNNATFGAQYPSQSALAATWSINRAKEFGLAIAYETRIS GGQQMLSPGVNLYRTPYNGRSAEYVSGEDPFLGAVLAPAIVNGIQAQGIQASGKHYLANE QEANRQAVNVVADERTLRELYLPGFESMVKNANVASIMCGFNKVNGDYACENHHLITEVL KGEWGYQGTVISDFNAIHDPFKGAWAGTDLDMPSGLQFTEANLLPYLWSGQLTQNVIDDK VKRNLRAVVSYDFQENLNTAKTLEHTEYGQRASLNAAREGIVLLRNADTAAGKPLLPLAR TARIAVIGDWANQAPASPFGTANSPPNSYVTELSGLQQLASNSANVTYLSALSLNPKAAV WYQPTSSGSGVSNAGVKAEYFSNTSLSGDPVLTRIEPGVNLNWTTSTNETSTGTTAVSGF SPTAGAFSARFSATIKPTVSGAHVFKVRADGPYKLWVDGKLVVQSDGVPYSSDVVNALTT SGKSAALVAGKSYNVKLEYRRVQGNFTPALGGLAGVQMSWASLRPPKDIASYDAVVIAAG TNYENEGEGSDHGYALPDQQAELIKFVTKANPNTIVVTHGGGVADMQPWAKKVGAALHAW FPGQQGGQALAEILYGKVNPSGKLPVTIDKKIEDNPSYASYPDPAAYRGDNPLTEIDYSE GLYMGYRGYDKKHAKPLYPFGFGLSYTTFGYSDLKLSTNVMTPGNTVNATFTLTNTGDKA GFEVAQLYIQPIAPQVDRPKKELKGFTKVYLEPGQSKTVSLPIDSRSLAYFVQNTDSWDV DAGKFKVWVGPDSENLTLQRTLVTLMPQHLTTRDSNPLPAPLQAAVQVSDSQAY > DME ID: DME2063 DME Name: Cytochrome P450 107L2 (cyp107) PDB ID: 2BVJ; 2C6H; 2CA0; 2CD8; 2VZ7; 2VZM; 2WHW; 2WI9; 3ZK5; 3ZPI; 4B7D; 4B7S; 4BF4; 4UMZ MRRTQQGTTASPPVLDLGALGQDFAADPYPTYARLRAEGPAHRVRTPEGDEVWLVVGYDR ARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVAREFTMRRVELLR PRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVF PDDPAQAQTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHIL LVAGHETTVNLIANGMYALLSHPDQLAALRADMTLLDGAVEEMLRYEGPVESATYRFPVE PVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAFGHGIHFCIGAPLA RLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRWRRGREAGRRTG > DME ID: DME2070 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MNRDNDKGKVLIRRSLIMALGKFFLLLVIVGRLYYLQVYQADRYKTLADENRISTRLLIP PRGVIYDRNGVMIATNTQNFQALIVAEQTPNVQETLDAFKKIMPLSADEEEKIKRDMKRN RSFVPIKIKENLTWEEVSRIQLNAADLPGIYIDEGLSRDYPFGPSMAHILGYVAAVNEKE AKQDDDPLLQVPGFKIGKSGIEKRYEKELRGKGGSLKLEVNAYGRIMKEIEKNDGIPGQP LTLTIDSRLQQKAFELFGEESGAAVLLDVNTGEILAFVSAPSFDPNLMTKGVSNTDWKAW LNNEKRPLTDKAISGQYSPGSTFKVLVALAALESGVIKPDTHFYCSGQMTLGNHIFHDWK RGGHGSLNVVEALAHSCDIFFYEVALRLGIEKIADMARRFGLGSRIDVGLENEKAGLIPD KEWKLRRFGEPWQQGESVISGIGQGYILTTPLQLATMVARIANGGYEVKPTFTKVKDKST IRKIDVADENIKLVKDGMFAVVNIPGSTAYRSHFDYNGQMMSGKTGSTQVRRITMKERQT RVLKQNELPWKYRDHGLFIAYAPHDNPRYAVAVLVEHGGGGSSAAAPIASKLLLETLKLD PVNEKVRTVE > DME ID: DME2071 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MKKKHMKWLFSGLMLMALCIGQPSSSEGTSPAWSVDEFIKDREGTFVIQEVKEKSPWVYN KKRANERFAPQSTFKVANALIGLQTGAVRDEYDIKYWDGVKREIDNWNKDHTLGSGMRDS VVWYYQAMARDIGEERMNHWVKAIHYGNEDISGGIDQFWLSSSLRISPVEQVHFLKQLYE ESLPFDLSVMRTVKRMMIQEEEKHATLYGKTGSGSGIGWYVGFIKHENKTYIFATNIEGT GLEAKEITYRILKKYHLIEASV > DME ID: DME2072 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MIGRRMGMGAMAALGLGMMAAGPSGARAASGAGKGQAGAGFSALPAVFAGIERRVGGRLG VAVLDTATGQRAGHREAERFPLTSTFKLLAAAAVLSRVDAGQARLDQRIRYGREKLVAYS PETEKHAGEEGMTLAAICEAAVTLSDNTAGNLMLEQIGGPAGLTAWLRSIGDTVTRLDRW ETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQAHLTGWLRANKTGDKRLRAGL PGGWQAGDKTGAGERGTNNDAGLLWPPGESAPILVAAYSTGGTAPSTERDAALAEVAAAI VAAKGP > DME ID: DME2077 DME Name: Alpha-galactosidase (melA) PDB ID: Not Available MAIRIEDQNLLFHLQTDHTSYIFHMMENGELGQIYYGKRVHSKPSYDNLVTREWHNAAAV WRLDHKDVQPQVLKQEYASLGKGDFRYPAYQVAQANGSRITEFKYESYELVDGKQRLAGL PSAFDDTDDDAQTLTIALRDKLLGLVMHLNYTIFPHQDVIVRSAEFQNQGNEKLRLNSAA SAQLDLPDADYDFIQFSGAWARERHMIRTHLRSGVQSVGSLRGTSSHQQNPFVMLARPNT DDAQGSVFGFNLIYSGNFSDQVQVDQYDASRVLVGINPEEFAWNLKPGDKFQTPEAVLSY TDAGMNQLSQQMGAFYQDHLVNPRFAHEQRPTLINNWEATFMDFDEDKLLSFATTAKKLG LEMFVLDDGWFGHRNNDDSSLGDWFVNEPKFPSGFGTFTQKIHDLGLKFGLWFEPEMISI DSELYKQHPDWLINAPGRHASPERQQFVLDMTRSEVVDYLFDAMSKIIEMTKLDYIKWDM NRNITETYSSQLSADDQLEVPHRYILGVYQLYDRLVKAYPDVLFESCSSGGGRFDLGMMY YAPQAWTSDDTDAVERMLIQFGTSYGYPQTMMGAHVSAVPNDQVGRITSLKTRANVAYFG DFGYELDITKMSPEEQQQVKEQTAFYKEHRQLFQFGKFYRIDNPFANGGNVMSWEVVSDD QKHAIAARYQILNRPNTGYIRLYLKGLDPDTKYTVNGGSEQFYGDELMNAGLFVSDILHE THGTDQSADFNSKLFVIDAVK > DME ID: DME2080 DME Name: Alpha-galactosidase (melA) PDB ID: Not Available MPVFINEETKLFHLQTKNTSYIFQILANEAAGQVYYGAKVPVKPSYSNLMTMEEHDCTNT LSEENTSFQLELVKQEYATQGKGDFPGGRLRYPIPRRLPDQEFEYQVTKSKREKAPAGSA ILFDDEGTDATSLTLILKDRLYDLRMNLHYTFFNDDDVIVRSASFENKGDTVMIDRALSA QLDLPDDNYDLLQFSGTWAREPNLYRNHLRPGTQSVASRRIKLQPPRNPAIILARPKHRI IIRVKPLVLTIVYSGSFLDTVEVDQFNTTRVVTGIHPDDFSWQLEAGQSFQTPEAVLSYT NAGMNALSQQMGRFYRDHLINPHFAKEDRPILINNWEATFMDFTEEKLMKIVTKAKETGI EMFVLDDGWFGHRDNDLTSLGDWFVDQKKFLNGVGGFASRVHKLGMKFGLWFEPEMISID SKLYEDHPDWMIQTKGRLATPARHQFVLDMARQEVVDDIFNKMSAVIKDTKLDYIKWDMN RTITEAFTATLPANRQQEFAHRYILGVYQLYERLTQAFPSVLFESCASGGGRFDLGMMYY APQAWCSDDTDAVERIYIQDGTSYGYIPSMWGAHVSAVPNDQVGRVTSLNTRAKVAYFRC LWLRTGLKRTVRRRAGNGLKNKSPFTSSTATSSNTGPSTGLTVQTPLPITSTGWQVVNDD QSEAIAVRFQILNKPNPGYIRFYFTGLDPEKTYQVNDDEETYSGAELMNAGYFVARIMPR SASPKPLADFNATMFVVKAV > DME ID: DME2081 DME Name: Alpha-galactosidase (melA) PDB ID: Not Available MPITYNEQSREFHLYNNKISYLIKILANEQLGQLYFGKRIPNRKNHDYLVENTYRPVTSY VFDDDYSFSLGNVKQEYPAYGTTDQRRPALDIKQPNGSRITDFKYVSHKIYAGKRKLTGL PATYVEDESEATTLEINLYDELIQVTLCLQYTIFENSAAIARSVKFSNDSDQKYQLKTAL SLNLDLPDANYEWLQFSGAWGRERHLHKTPLRPGIQAINSARGASSHMQNPFVILKRPFT TEEQGEALGVSFVYSGNFLAQAEVDEYSVTRLQIGIDPFQFSWCLKPNETFQTPEAILAY TSEGLNQLSQTFQKLYTTRLARGYWRDKERPILINNWEATYFDFTEEKLLSIAKKAKELG IELFVLDDGWFGERTKETAGLGDWYVNRNRLKNGISGLSRKIHDLGMMFGLWFEPEMVNK DSDLYRKHPDYIIETPKRHASHGRKQYVLDFSRKEVVDNIYEQLVKILDEGEIDYIKWDM NRNITECYSIAYPSEQQGEIMHRYILGVYDLYERLIERYPKILFESCASGGGRFDAGMLY YAPQAWTSDDSDAIERLKIQYGTSFGYPQSMMGAHVSASPNEQLGRNTPLKIRGDVAFFG AFGYELDLDKLSSTELASIKKQIELMKKYRSIFQYGTFYRLKSPFEGNIVSWMVVSEDKS QAIVGYYKILNDVNCEYRRLCLPGLDADTLYNVQEELGSYLGNFTGDELANIGLVTTDAS AGQNQETTDFYSKLFILERCGELSD > DME ID: DME2082 DME Name: Alpha-galactosidase (melA) PDB ID: Not Available MSIHVNEANLTFHLQTDHTSYIFQIMKNGEAGQIYYGPRIHVQPTYQNLMSQEWRDATPS LNEENPNFQPATIKAEYASLGKGDFRQPAFQVTQTNGSRITELTYDHYQLLTGKQRLANL PSTFDDTDDDAQTLVVSFNDRITGLALDLNYSLFPHQDVIVKSAKFINPSSEKLVLNRAL SSQLDLPDANYDLIQFSGTWARERHLYRHPLRPGMQSISSLRMASSHQQNPFMMLARPQT TDEQGAVFGFNLVYSGNFLDAVEVDQYSTSRILTGINPDEFGWNLAPQATFQTPEAILSY TSAGMNQLSQQMASFYQQHLVNPRFAHEERPVLINNWEATYFDFNEAKLMTIVNQAKRLG IEMFVLDDGWFGHRDDDTTSLGDWFVDQKKFPDGIEHFSQAVHQQGMKFGLWFEPEMISV DSGLYQQHPDWLIHAPKSTPTPGRHQFVLDMARPEVVDYLFKLMSQMIESANLDYIKWDM NRYATEMFSSRLTSDQQLELPHRYILGVYQLYARLTQAYPNVLFESCASGGGRFDLGMMY YAPQAWTSDDTDAAERLLIQFGTSYGYPQAMMGAHVSAVPNDQMGRITSLKTRGAVAFFG DLGYELDITKMAPTELDQVKKQVAFYKRYRQLFQFGKFYRIDSPFVGDGNVTSWQVVSDD QKQAIAARYQLLNHPNAPYTRFYFKGLRPNQRYQINDDPSTYYGDELMNAGYFVPTILAD GQESKDFYTQLFVVTAI > DME ID: DME2085 DME Name: Cytochrome P450 107W1 (cyp107) PDB ID: 2BVJ; 2C6H; 2CA0; 2CD8; 2VZ7; 2VZM; 2WHW; 2WI9; 3ZK5; 3ZPI; 4B7D; 4B7S; 4BF4; 4UMZ MRRTQQGTTASPPVLDLGALGQDFAADPYPTYARLRAEGPAHRVRTPEGDEVWLVVGYDR ARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVAREFTMRRVELLR PRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVF PDDPAQAQTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHIL LVAGHETTVNLIANGMYALLSHPDQLAALRADMTLLDGAVEEMLRYEGPVESATYRFPVE PVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAFGHGIHFCIGAPLA RLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRWRRGREAGRRTG > DME ID: DME2100 DME Name: Beta-lactamase (blaB) PDB ID: Not Available MQRIGVTDYTILGTVKGAELELVRFTHPFMGFDVPAILGDHVTRMPVPVPFTPRLPRPGR LCDRSEIRPGKPLTRLARTALICRALIRRWMARTSYSDSVNCHTQPISAIFDYKDLRFEP PSNRISPAGQTSVDRLLQLSQGQAVEGQSAVARLTGEKKNHPGAQYANRLSPRIANNHPA TQQTLFELGSGAKERNAINVSYLTALGTPGFTLMLPARMLCGIVSDNNFTQKQLCPSPAR CTRGPAEPAKRGPWLEPGLVIRKDGLRTGKLLSSLRGLCLTVLRFQPTVPCFCRLALSSS VAISSTGLVNFSR > DME ID: DME2101 DME Name: Glutamate decarboxylase (gadB) PDB ID: Not Available AMENYCVSMIAHLWGIPDNEKIYDDFIGTSTVGSSEGCMLGGLALLHSWKHRAKAAGFDI EDLHSHKPNLVIMSGYQVVWEKFCTYWNVEMRQVPINGDQVSLDMDHVMDYVDENTIGII GIEGITYTGSVDDIQTLDNLVSEYNKTATMPVRIHVDAAFGGLFAPFVDGFNPWDFRLKN VVSINVSGHKYGMVYPGLGWIVWRHNTADILPAEMRFQVPYLGKTVDSIAINFSHSGAHI SAQYYNFIRFGLSGYKTIMQNVRKVSLKLTAALKTYGIFDILVDGSQLPINCWKLADDAP VGWTLYDLESELAKYG > DME ID: DME2102 DME Name: Phosphotransferase enzyme strA (strA) PDB ID: Not Available MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASRRGELAGERDRLIWLKG RGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAWPSMGQQLGAVHSLSVDQC PFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLLARVERELPVRLDQERTDMVV CHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLALMIANAEENWAAPDEAERAFAV LFNVLGIEAPDRERLAFYLRLDPLTWG > DME ID: DME2103 DME Name: Phosphotransferase enzyme strB (strB) PDB ID: Not Available MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIEDIADELRGADYLV WRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIAAELMAKLYAASEEPLP SALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNASELRGLHGDLHHENIMF SSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPRRLL DQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY > DME ID: DME2104 DME Name: FMN-dependent NADH-azoreductase (azoR1) PDB ID: 2V9C; 3KEG; 3LT5; 3R6W; 4N65; 4N9Q MSRILAVHASPRGERSQSRRLAEVFLAAYREAHPQARVARREVGRVPLPAVTEAFVAAAF HPQPEQRSLAMQADLALSDQLVGELFDSDLLVISTPMYNFSVPSGLKAWIDQIVRLGVTF DFVLDNGVAQYRPLLRGKRALIVTSRGGHGFGPGGENQAMNHADPWLRTALGFIGIDEVT VVAAEGEESGGRSFEDSCDEAEQRLLALARSA >END