| Disease Specific Interactions between Host Protein and DME (HOSPPI) |
| ICD Disease Classification Healthy |
| ICD-11: Healthy |
Click to Show/Hide the Full List of HOSPPI: 2 HOSPPI
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| Oligomerization |
| UDPGT 1-1 (UGT1A1) |
Health |
Heterodimer |
| Uniprot ID |
|
| Interaction Name |
UGT1A1-UGT1A7 heterodimerization |
[1] |
| Studied Cell Lines |
Monkey kidney fibroblast-like cell line (COS) |
| Affected Substrate(s): |
2-Napthol
|
| Description |
UDPGT 1-1 (UGT1A1) is reported to heterodimerize with the UGT1A7 protein, which leads to a slight effect on the enzyme activity of UDP-glucuronosyltransferase 1A7. As a result, the interaction between UGT1A1 and UGT1A7 can slightly affect the drug-metabolizing process of UDP-glucuronosyltransferase 1A7. |
| UDPGT 1-7 (UGT1A7) |
Health |
Homodimer |
| Uniprot ID |
|
| Interaction Name |
UGT1A7-UGT1A7 homodimerization |
[1] |
| Studied Cell Lines |
Monkey kidney fibroblast-like cell line (COS) |
| Affected Substrate(s): |
2-Napthol
|
| Description |
UDP-glucuronosyltransferase 1-7 (UGT1A7) is reported as a homodimer, which leads to a slight effect on the enzyme activity of drug-metabolizing enzyme UDP-glucuronosyltransferase 1A7. As a result, the UGT1A7 homodimerization can slightly affect the drug-metabolizing process of UDP-glucuronosyltransferase 1A7. |
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