| Disease Specific Interactions between Host Protein and DME (HOSPPI) |
| ICD Disease Classification 14 Skin diseases |
| ICD-11: EA80 Atopic dermatitis |
Click to Show/Hide the Full List of HOSPPI: 2 HOSPPI
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| Transcription-factor regulation |
| Myeloid zinc finger 1 (MZF1) |
Atopic dermatitis |
Activation |
| Uniprot ID |
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| Interaction Name |
MZF1-BLMH interaction |
[1] |
| Studied Cell Lines |
Epidermal keratinocytes |
| Ensembl ID |
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| Description |
Myeloid zinc finger 1 (MZF1) is reported to activate the transcription of BLMH gene, which leads to an increased expression of the drug-metabolizing enzyme Bleomycin hydrolase. As a result, the interaction between MZF1 and BLMH can activate the drug-metabolizing process of Bleomycin hydrolase. |
| Transcription factor Sp1 (SP1) |
Atopic dermatitis |
Activation |
| Uniprot ID |
|
| Interaction Name |
SP1-BLMH interaction |
[1] |
| Studied Cell Lines |
Epidermal keratinocytes |
| Ensembl ID |
|
| Description |
Transcription factor Sp1 (SP1) is reported to activate the transcription of BLMH gene, which leads to an increased expression of the drug-metabolizing enzyme Bleomycin hydrolase. As a result, the interaction between SP1 and BLMH can activate the drug-metabolizing process of Bleomycin hydrolase. |
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