| Disease Specific Interactions between Host Protein and DME (HOSPPI) |
| Drug co-metabolism |
| Cometabolized drug: Chondroitin sulfate |
Click to Show/Hide the Full List of HOSPPI: 6 HOSPPI
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| Alpha-L-iduronidase (IDUA) |
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| DME ID |
DME0104
DME Info
|
| Uniprot ID |
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| Interaction Name |
IDUA-hyaL interaction |
[1], [2], [3] |
| Description |
The interaction, between human Alpha-L-iduronidase and Hyaluronate lyase from Streptobacillus moniliformis which collectively metabolize the drug Chondroitin sulfate, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| Arylsulfatase B (ARSB) |
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| DME ID |
DME0105
DME Info
|
| Uniprot ID |
|
| Interaction Name |
ARSB-hyaL interaction |
[1], [2], [3] |
| Description |
The interaction, between human Arylsulfatase B and Hyaluronate lyase from Streptobacillus moniliformis which collectively metabolize the drug Chondroitin sulfate, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| Beta-glucuronidase (GUSB) |
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| DME ID |
DME0106
DME Info
|
| Uniprot ID |
|
| Interaction Name |
GUSB-hyaL interaction |
[1], [2], [3] |
| Description |
The interaction, between human Beta-glucuronidase and Hyaluronate lyase from Streptobacillus moniliformis which collectively metabolize the drug Chondroitin sulfate, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| Chondroitin 6-sulfotransferase (CHST3) |
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| DME ID |
DME0632
DME Info
|
| Uniprot ID |
|
| Interaction Name |
CHST3-hyaL interaction |
[1], [2], [4] |
| Description |
The interaction, between human Chondroitin 6-sulfotransferase and Hyaluronate lyase from Streptobacillus moniliformis which collectively metabolize the drug Chondroitin sulfate, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| Iduronate 2-sulfatase (IDS) |
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| DME ID |
DME0108
DME Info
|
| Uniprot ID |
|
| Interaction Name |
IDS-hyaL interaction |
[1], [2], [3] |
| Description |
The interaction, between human Iduronate 2-sulfatase and Hyaluronate lyase from Streptobacillus moniliformis which collectively metabolize the drug Chondroitin sulfate, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| N-acetyl-beta-glucosaminidase beta (HEXB) |
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| DME ID |
DME0107
DME Info
|
| Uniprot ID |
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| Interaction Name |
HEXB-hyaL interaction |
[1], [2], [3] |
| Description |
The interaction, between human N-acetyl-beta-glucosaminidase beta and Hyaluronate lyase from Streptobacillus moniliformis which collectively metabolize the drug Chondroitin sulfate, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
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