| Disease Specific Interactions between Host Protein and DME (HOSPPI) |
| Drug co-metabolism |
| Cometabolized drug: Omega-3 Fatty acids |
Click to Show/Hide the Full List of HOSPPI: 2 HOSPPI
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| Arachidonate 5-lipoxygenase (ALOX5) |
Click to Show/Hide the Cometabolization Info |
| DME ID |
DME0201
DME Info
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| Uniprot ID |
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| Interaction Name |
ALOX5-cyp147 interaction |
[1], [2] |
| Description |
The interaction, between human Arachidonate 5-lipoxygenase and Cytochrome P450 147G1 from Mycobacterium marinum which collectively metabolize the drug Omega-3 Fatty acids, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| Prostaglandin G/H synthase 2 (COX-2) |
Click to Show/Hide the Cometabolization Info |
| DME ID |
DME0114
DME Info
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| Uniprot ID |
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| Interaction Name |
COX-2-cyp147 interaction |
[1], [3] |
| Description |
The interaction, between human Prostaglandin G/H synthase 2 and Cytochrome P450 147G1 from Mycobacterium marinum which collectively metabolize the drug Omega-3 Fatty acids, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
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