Details of Microbiome-DME Interaction (MICBIO)

General Information of Drug-Metabolizing Enzyme (DME ID: DME0072)
DME Name UDP-glucuronosyltransferase 1A6 (UGT1A6), Homo sapiens DME Info
UniProt ID
UD16_HUMAN
EC Number    EC: 2.4.1.17     (Click to Show/Hide the Complete EC Tree)
Transferase
Glycosyltransferases
Hexosyltransferase
EC: 2.4.1.17
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Interactome
Interactions between Microbiome and DME (MICBIO)
      Bacteria: Actinobacteria
                  Bifidobacterium adolescentis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bifidobacterium adolescentis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bifidobacterium breve (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bifidobacterium breve co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bifidobacterium longum (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bifidobacterium longum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bifidobacterium ruminatum (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bifidobacterium ruminatum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Collinsella intestinalis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Collinsella intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Eggerthella lenta (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Eggerthella lenta co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Bacteroidetes
                  Alistipes indistinctus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Alistipes indistinctus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides coprophilus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides coprophilus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides dorei (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides dorei co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides eggerthii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides eggerthii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides fragilis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides fragilis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides fragilis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides intestinalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides ovatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides ovatus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides sartorii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides sartorii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides sartorii co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides stercoris (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides stercoris co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides thetaiotaomicron (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides thetaiotaomicron co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides thetaiotaomicron co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides uniformis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides uniformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides vulgatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides vulgatus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides vulgatus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides xylanisolvens (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides xylanisolvens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides xylanisolvens co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Odoribacter splanchnicus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Odoribacter splanchnicus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Odoribacter splanchnicus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Parabacteroides distasonis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Parabacteroides distasonis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Parabacteroides distasonis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Parabacteroides johnsonii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Parabacteroides johnsonii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Parabacteroides merdae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Parabacteroides merdae co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Prevotella copri (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Prevotella copri co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [5]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Prevotella copri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Firmicutes
                  Anaerobutyricum hallii (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Anaerobutyricum hallii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Anaerococcus hydrogenalis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Anaerococcus hydrogenalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Anaerostipes hadrus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Anaerostipes hadrus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacillus megaterium (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacillus megaterium co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [7]
                  Bacteroides pectinophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Bacteroides pectinophilus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Blautia hansenii (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Blautia hansenii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Blautia luti (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Blautia luti co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridioides difficile (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Clostridioides difficile co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [8]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Clostridioides difficile co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridium botulinum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Clostridium botulinum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridium scindens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Clostridium scindens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridium spiroforme (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Clostridium spiroforme co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Coprococcus comes (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Coprococcus comes co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Dorea formicigenerans (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Dorea formicigenerans co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterocloster asparagiformis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Enterocloster asparagiformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterocloster bolteae (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Enterocloster bolteae co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterococcus faecalis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Enterococcus faecalis co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [8]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Enterococcus faecalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Erysipelatoclostridium ramosum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Erysipelatoclostridium ramosum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Eubacterium rectale (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Eubacterium rectale co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Holdemanella biformis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Holdemanella biformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Hungatella hathewayi (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Hungatella hathewayi co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Jeotgalicoccus psychrophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Jeotgalicoccus psychrophilus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [5]
                  Lactobacillus reuteri (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Lactobacillus reuteri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Marvinbryantia formatexigens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Marvinbryantia formatexigens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Roseburia intestinalis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Roseburia intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Ruminococcus albus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Ruminococcus albus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [5]
                  Ruminococcus torques (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Ruminococcus torques co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Subdoligranulum variabile (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Subdoligranulum variabile co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Lentisphaerae
                  Victivallis vadensis (PVC bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Victivallis vadensis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Proteobacteria
                  Citrobacter freundii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Citrobacter freundii co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [8]
                  Edwardsiella tarda (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Edwardsiella tarda co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterobacter cancerogenus (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Enterobacter cancerogenus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Escherichia coli (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Escherichia coli co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [8]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Escherichia coli co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Helicobacter apodemus (epsilon-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Helicobacter apodemus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [5]
                  Proteus penneri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Proteus penneri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Providencia alcalifaciens (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Providencia alcalifaciens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Providencia rettgeri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Providencia rettgeri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Providencia stuartii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Providencia stuartii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Salmonella enterica (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Salmonella enterica co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Verrucomicrobia
                  Akkermansia muciniphila (verrucomicrobiae) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) and Akkermansia muciniphila co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Fungi: Ascomycota
                  Saccharomyces cerevisiae (ascomycota) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A6 (UGT1A6) metabolizes the drug Acetaminophen, and Saccharomyces cerevisiae further metabolizes its metabolite (1-Phenyl-1,2-propanedione), which can indirectly affect efficacy, safety or bioavailability of this drug. [6], [8]
References
1 Characterization of rat intestinal microsomal UDP-glucuronosyltransferase activity toward mycophenolic acid. Drug Metab Dispos. 2006 Sep;34(9):1632-9.
2 Mapping human microbiome drug metabolism by gut bacteria and their genes. Nature. 2019 Jun;570(7762):462-467.
3 S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen. Br J Clin Pharmacol. 2005 Oct;60(4):423-33.
4 Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria. Allergy Asthma Immunol Res. 2011 Oct;3(4):273-6.
5 Gut microbiota-mediated drug-drug interaction between amoxicillin and aspirin. Sci Rep. 2019 Nov 7;9(1):16194.
6 UGT1A6 and UGT2B15 polymorphisms and acetaminophen conjugation in response to a randomized, controlled diet of select fruits and vegetables. Drug Metab Dispos. 2011 Sep;39(9):1650-7.
7 The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities. Trends Biotechnol. 2007 Jul;25(7):289-98.
8 Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice. J Hepatol. 2018 Jul;69(1):51-59.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.