| General Information of Drug-Metabolizing Enzyme (DME ID: DME0407) |
| DME Name |
Aquaporin adipose (AQP7), Homo sapiens
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DME Info
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| UniProt ID |
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| EC Number |
EC: 3.1.1.- (Click to Show/Hide the Complete EC Tree)
Hydrolases
Ester bond hydrolase
Carboxylic ester hydrolase
EC: 3.1.1.-
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| Lineage |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Interactome |
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| Interactions between Microbiome and DME (MICBIO)
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| Bacteria: Firmicutes |
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| Lactobacillus brevis (firmicutes) |
Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
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| Glycerol |
Click to Show/Hide the Detail |
| Drug ID |
DR0784
Drug Info
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| Interaction Mechanism |
Human Aquaporin adipose (AQP7) and Lactobacillus brevis co-metabolize the drug Glycerol, which can collectively affect efficacy, safety or bioavailability of this drug. |
[1], [2] |
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| References |
| 1 |
Aquaporins in the human testis and spermatozoa - identification, involvement in sperm volume regulation and clinical relevance. Int J Androl. 2010 Aug 1;33(4):629-41.
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| 2 |
Expression and characterization of a novel 1,3-propanediol dehydrogenase from Lactobacillus brevis. Appl Biochem Biotechnol. 2016 Jul;179(6):959-72.
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