Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1140)
DME Name Beta-galactosidase (bgaB), Bifidobacterium adolescentis DME Info
UniProt ID
BGAL_BIFAA
EC Number    EC: 3.2.1.23     (Click to Show/Hide the Complete EC Tree)
Hydrolases
Glycosylase
O/S-glycosyl compound glycosidase
EC: 3.2.1.23
Lineage    Species: Bifidobacterium adolescentis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
Species: Bifidobacterium adolescentis
Subspecies: Bifidobacterium adolescentis DSM 20083
Subspecies: Bifidobacterium adolescentis YIT 4011(T)
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Royalisin defensin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03113   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Royalisin defensin-1 inhibits the drug-metabolizing activity of Beta-galactosidase (bgaB) from Bifidobacterium adolescentis [1], [2]
References
1 A potent antibacterial protein in royal jellyPurification and determination of the primary structure of royalisin. J Biol Chem. 1990 Jul 5;265(19):11333-7.
2 Two structurally different defensin genes, one of them encoding a novel defensin isoform, are expressed in honeybee Apis mellifera. Insect Biochem Mol Biol. 2005 Jan;35(1):11-22.

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