Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1264)
DME Name Unclear metabolic mechanism (DME-unclear), Enterococcus malodoratus DME Info
Lineage    Species: Enterococcus malodoratus     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Enterococcaceae
Genus: Enterococcus
Species: Enterococcus malodoratus
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:      10 Xenobiotics
                              Bacteriocin lacticin 3147 A2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02379   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bacteriocin lacticin 3147 A2 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [1]
                              Bavaricin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02417   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bavaricin-A inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [2]
                              Carnobacteriocin BM1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02719   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Carnobacteriocin BM1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [3]
                              Carnobacteriocin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02720   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Carnobacteriocin-A inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [4], [5]
                              Curvaticin FS47 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03026   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Curvaticin FS47 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [6]
                              Lacticin 3147 LtnA1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03770   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lacticin 3147 LtnA1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [1]
                              Nisin A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04318   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nisin A inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [7]
                              Nisin Z Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04321   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Nisin Z inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [8]
                              Plantaricin S alpha Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04620   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plantaricin S alpha inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [9], [10]
                              Plantaricin S beta Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04621   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plantaricin S beta inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Enterococcus malodoratus [9], [10]
References
1 Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity. Biochemistry. 2004 Mar 23;43(11):3049-56.
2 Antimicrobial activity of lactic acid bacteria isolated from sour doughs: purification and characterization of bavaricin A, a bacteriocin produced by Lactobacillus bavaricus MI401. J Appl Bacteriol. 1993 Aug;75(2):113-22.
3 Chemical and genetic characterization of bacteriocins produced by Carnobacterium piscicola LV17B. J Biol Chem. 1994 Apr 22;269(16):12204-11.
4 Characteristics and genetic determinant of a hydrophobic peptide bacteriocin, carnobacteriocin A, produced by Carnobacterium piscicola LV17A. Microbiology. 1994 Mar;140 ( Pt 3):517-26.
5 Purification and cloning of piscicolin 61, a bacteriocin from Carnobacterium piscicola LV61. Curr Microbiol. 1994 Aug;29(2):63-8.
6 Purification and partial amino acid sequence of curvaticin FS47, a heat-stable bacteriocin produced by Lactobacillus curvatus FS47. Appl Environ Microbiol. 1994 Jun;60(6):2191-5.
7 The structure of nisin. J Am Chem Soc. 1971 Sep 8;93(18):4634-5.
8 The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics. Nat Struct Mol Biol. 2004 Oct;11(10):963-7.
9 Purification and partial amino acid sequence of plantaricin S, a bacteriocin produced by Lactobacillus plantarum LPCO10, the activity of which depends on the complementary action of two peptides. Appl Environ Microbiol. 1995 Dec;61(12):4459-63.
10 Molecular analysis of the locus responsible for production of plantaricin S, a two-peptide bacteriocin produced by Lactobacillus plantarum LPCO10. Appl Environ Microbiol. 1998 May;64(5):1871-7.

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