Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1353)
DME Name Gamma-glutamylcyclotransferase (GGCT), Ralstonia solanacearum DME Info
UniProt ID
A0A073ACX1_RALSL
EC Number    EC: 4.3.2.9     (Click to Show/Hide the Complete EC Tree)
Lyases
Carbon-nitrogen lyase
Amidine-lyase
EC: 4.3.2.9
Lineage    Species: Ralstonia solanacearum     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Burkholderiales
Family: Burkholderiaceae
Genus: Ralstonia
Species: Ralstonia solanacearum
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:        6 Xenobiotics
                              Defensin So-D1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03104   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin So-D1 inhibits the drug-metabolizing activity of Gamma-glutamylcyclotransferase (GGCT) from Ralstonia solanacearum [1]
                              Defensin So-D2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03106   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin So-D2 inhibits the drug-metabolizing activity of Gamma-glutamylcyclotransferase (GGCT) from Ralstonia solanacearum [1]
                              Defensin So-D5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03107   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin So-D5 inhibits the drug-metabolizing activity of Gamma-glutamylcyclotransferase (GGCT) from Ralstonia solanacearum [1]
                              Defensin So-D6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03108   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin So-D6 inhibits the drug-metabolizing activity of Gamma-glutamylcyclotransferase (GGCT) from Ralstonia solanacearum [1]
                              Snakin-1 StSN1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04960   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Snakin-1 StSN1 inhibits the drug-metabolizing activity of Gamma-glutamylcyclotransferase (GGCT) from Ralstonia solanacearum [2], [3]
                              Snakin-2 StSN2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04961   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Snakin-2 StSN2 inhibits the drug-metabolizing activity of Gamma-glutamylcyclotransferase (GGCT) from Ralstonia solanacearum [2]
References
1 Novel defensin subfamily from spinach (Spinacia oleracea). FEBS Lett. 1998 Sep 18;435(2-3):159-62.
2 Snakin-2, an antimicrobial peptide from potato whose gene is locally induced by wounding and responds to pathogen infection. Plant Physiol. 2002 Mar;128(3):951-61.
3 Snakin-1, a peptide from potato that is active against plant pathogens. Mol Plant Microbe Interact. 1999 Jan;12(1):16-23.

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