Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1386)
DME Name	Unclear metabolic mechanism (DME-unclear), Bifidobacterium adolescentis	DME Info
Lineage	Species: Bifidobacterium adolescentis (Click to Show/Hide the Complete Species Lineage) Kingdom: Bacteria Phylum: Actinobacteria Class: Actinobacteria Order: Bifidobacteriales Family: Bifidobacteriaceae Genus: Bifidobacterium Species: Bifidobacterium adolescentis Subspecies: Bifidobacterium adolescentis ATCC 15703
Interactome

Interactions between Xenobiotics and DME (XEOTIC)
Amino Acid(s), Peptide(s) or Protein(s)
Peptide		Click to Show/Hide the Full List of Xenobiotics: 1 Xenobiotics
Royalisin defensin-1		Click to Show/Hide the Detail			Inhibition
XEOTIC ID	XEO03113 XEOTIC Info		Gene Form	Protein
Classification	Peptide
DME Modulation	Royalisin defensin-1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Bifidobacterium adolescentis				[1], [2]

References
1	A potent antibacterial protein in royal jellyPurification and determination of the primary structure of royalisin. J Biol Chem. 1990 Jul 5;265(19):11333-7.
2	Two structurally different defensin genes, one of them encoding a novel defensin isoform, are expressed in honeybee Apis mellifera. Insect Biochem Mol Biol. 2005 Jan;35(1):11-22.

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