Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1430)
DME Name Unclear metabolic mechanism (DME-unclear), Helicobacter pylori DME Info
Lineage    Species: Helicobacter pylori     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Epsilonproteobacteria
Order: Campylobacterales
Family: Helicobacteraceae
Genus: Helicobacter
Species: Helicobacter pylori
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:        5 Xenobiotics
                              Defensin-like longicornsin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03958   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin-like longicornsin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Helicobacter pylori [1]
                              Mutacin II mutacin H-29B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04156   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mutacin II mutacin H-29B inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Helicobacter pylori [2]
                              Odorranain-W2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04382   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Odorranain-W2 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Helicobacter pylori (MIC = 20 ug/ml) [3]
                              Pleurain-A1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04630   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-A1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Helicobacter pylori (MIC = 30 ug/ml) [4]
                              Pleurain-A2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04631   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurain-A2 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Helicobacter pylori (MIC = 30 ug/ml) [4]
References
1 A novel defensin-like peptide from salivary glands of the hard tick, Haemaphysalis longicornis. Protein Sci. 2010 Mar;19(3):392-7.
2 Isolation and biochemical characterization of a novel lantibiotic mutacin from Streptococcus mutans. J Bacteriol. 1994 Jul;176(14):4316-20.
3 An antimicrobial peptide with antimicrobial activity against Helicobacter pylori. Peptides. 2007 Aug;28(8):1527-31.
4 A new family of antimicrobial peptides from skin secretions of Rana pleuraden. Peptides. 2007 Oct;28(10):2069-74.

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