Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1453)
DME Name	Unclear metabolic mechanism (DME-unclear), Providencia rettgeri	DME Info
Lineage	Species: Providencia rettgeri (Click to Show/Hide the Complete Species Lineage) Kingdom: Bacteria Phylum: Proteobacteria Class: Gammaproteobacteria Order: Enterobacterales Family: Morganellaceae Genus: Providencia Species: Providencia rettgeri Subspecies: Providencia rettgeri DSM 1131
Interactome

Interactions between Xenobiotics and DME (XEOTIC)
Amino Acid(s), Peptide(s) or Protein(s)
Peptide		Click to Show/Hide the Full List of Xenobiotics: 1 Xenobiotics
Hydramacin Hm-1		Click to Show/Hide the Detail			Inhibition
XEOTIC ID	XEO03609 XEOTIC Info		Gene Form	Protein
Classification	Peptide
DME Modulation	Hydramacin Hm-1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Providencia rettgeri				[1], [2]

References
1	Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence. Dev Comp Immunol. 2009 Apr;33(4):559-69.
2	Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra. J Biol Chem. 2009 Jan 16;284(3):1896-905.

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