Details of Xenobiotics-DME Interaction (XEOTIC)
| General Information of Drug-Metabolizing Enzyme (DME ID: DME1484) | |||||
|---|---|---|---|---|---|
| DME Name | Beta-lactamase (blaB), Enterobacter cancerogenus | DME Info | |||
| UniProt ID | |||||
| EC Number | EC: 3.5.2.6 (Click to Show/Hide the Complete EC Tree) | ||||
| Lineage | Species: Enterobacter cancerogenus (Click to Show/Hide the Complete Species Lineage) | ||||
| Interactome | |||||
| Interactions between Xenobiotics and DME (XEOTIC) | |||||
|---|---|---|---|---|---|
| Amino Acid(s), Peptide(s) or Protein(s) | |||||
| Peptide | Click to Show/Hide the Full List of Xenobiotics: 1 Xenobiotics | ||||
| V. philippinarum beta defensin VpBD | Click to Show/Hide the Detail | Inhibition | |||
| XEOTIC ID | XEO05260 XEOTIC Info | Gene Form | Protein | ||
| Classification | Peptide | ||||
| DME Modulation | V. philippinarum beta defensin VpBD inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Enterobacter cancerogenus (MIC = 13.13-26.26 microM) | [1] | |||
| References | |||||
| 1 | Molecular characterization of a novel big defensin from clam Venerupis philippinarum. PLoS One. 2010 Oct 20;5(10):e13480. | ||||
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