Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1495)
DME Name	Glucansucrase (gtf106B), Lactobacillus reuteri	DME Info
UniProt ID	Q5SBN3_LACRE
EC Number	EC: 2.4.1.5 (Click to Show/Hide the Complete EC Tree) Transferase Glycosyltransferases Hexosyltransferase EC: 2.4.1.5
Lineage	Species: Lactobacillus reuteri (Click to Show/Hide the Complete Species Lineage) Kingdom: Bacteria Phylum: Firmicutes Class: Bacilli Order: Lactobacillales Family: Lactobacillaceae Genus: Lactobacillus Species: Lactobacillus reuteri Subspecies: Lactobacillus reuteri 121
Interactome

Interactions between Xenobiotics and DME (XEOTIC)
Amino Acid(s), Peptide(s) or Protein(s)
Peptide		Click to Show/Hide the Full List of Xenobiotics: 2 Xenobiotics
Garvicin ML		Click to Show/Hide the Detail			Inhibition
XEOTIC ID	XEO03473 XEOTIC Info		Gene Form	Protein
Classification	Peptide
DME Modulation	Garvicin ML inhibits the drug-metabolizing activity of Glucansucrase (gtf106B) from Lactobacillus reuteri				[1]
Nisin F		Click to Show/Hide the Detail			Inhibition
XEOTIC ID	XEO04319 XEOTIC Info		Gene Form	Protein
Classification	Peptide
DME Modulation	Nisin F inhibits the drug-metabolizing activity of Glucansucrase (gtf106B) from Lactobacillus reuteri				[2]

References
1	Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos). Appl Environ Microbiol. 2011 Jan;77(1):369-73.
2	Characterization of the structural gene encoding nisin F, a new lantibiotic produced by a Lactococcus lactis subsplactis isolate from freshwater catfish (Clarias gariepinus). Appl Environ Microbiol. 2008 Jan;74(2):547-9.

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