General Information of Drug-Metabolizing Enzyme (DME ID: DME1552)
DME Name Cytochrome P450 142A1 (cyp142), Mycobacterium tuberculosis DME Info
UniProt ID
CP142_MYCTU
EC Number    EC: 1.14.15.28     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
Oxygen paired donor oxidoreductase
Iron-sulfur protein donor oxidoreductase
EC: 1.14.15.28
Lineage    Species: Mycobacterium tuberculosis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Corynebacteriales
Family: Mycobacteriaceae
Genus: Mycobacterium
Species: Mycobacterium tuberculosis
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:        2 Xenobiotics
                              Lariatins A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03807   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lariatins A inhibits the drug-metabolizing activity of Cytochrome P450 142A1 (cyp142) from Mycobacterium tuberculosis [1]
                              Lariatins B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03808   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lariatins B inhibits the drug-metabolizing activity of Cytochrome P450 142A1 (cyp142) from Mycobacterium tuberculosis [1]
References
1 Lariatins, antimycobacterial peptides produced by Rhodococcus spK01-B0171, have a lasso structure. J Am Chem Soc. 2006 Jun 14;128(23):7486-91.

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