Details of Xenobiotics-DME Interaction (XEOTIC)
| General Information of Drug-Metabolizing Enzyme (DME ID: DME1662) | |||||
|---|---|---|---|---|---|
| DME Name | Cytochrome P450 121A1 (cyp121), Mycobacterium tuberculosis | DME Info | |||
| UniProt ID | |||||
| EC Number | EC: 1.14.19.70 (Click to Show/Hide the Complete EC Tree) | ||||
| Lineage | Species: Mycobacterium tuberculosis (Click to Show/Hide the Complete Species Lineage) | ||||
| Interactome | |||||
| Interactions between Xenobiotics and DME (XEOTIC) | |||||
|---|---|---|---|---|---|
| Amino Acid(s), Peptide(s) or Protein(s) | |||||
| Peptide | Click to Show/Hide the Full List of Xenobiotics: 2 Xenobiotics | ||||
| Lariatins A | Click to Show/Hide the Detail | Inhibition | |||
| XEOTIC ID | XEO03807 XEOTIC Info | Gene Form | Protein | ||
| Classification | Peptide | ||||
| DME Modulation | Lariatins A inhibits the drug-metabolizing activity of Cytochrome P450 121A1 (cyp121) from Mycobacterium tuberculosis | [1] | |||
| Lariatins B | Click to Show/Hide the Detail | Inhibition | |||
| XEOTIC ID | XEO03808 XEOTIC Info | Gene Form | Protein | ||
| Classification | Peptide | ||||
| DME Modulation | Lariatins B inhibits the drug-metabolizing activity of Cytochrome P450 121A1 (cyp121) from Mycobacterium tuberculosis | [1] | |||
| References | |||||
| 1 | Lariatins, antimycobacterial peptides produced by Rhodococcus spK01-B0171, have a lasso structure. J Am Chem Soc. 2006 Jun 14;128(23):7486-91. | ||||
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