Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1687)
DME Name D-Lactate dehydrogenase (ldhA), Lactobacillus delbrueckii DME Info
UniProt ID
LDHD_LACDA
EC Number    EC: 1.1.1.28     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
CH-OH donor oxidoreductase
NAD/NADP oxidoreductase
EC: 1.1.1.28
Lineage    Species: Lactobacillus delbrueckii     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species: Lactobacillus delbrueckii
Subspecies: Lactobacillus delbrueckii subsp. bulgaricus
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Bacteriocin hiracin-JM79 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02377   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bacteriocin hiracin-JM79 inhibits the drug-metabolizing activity of D-Lactate dehydrogenase (ldhA) from Lactobacillus delbrueckii [1]
References
1 Amino acid and nucleotide sequence, adjacent genes, and heterologous expression of hiracin JM79, a sec-dependent bacteriocin produced by Enterococcus hirae DCH5, isolated from Mallard ducks (Anas platyrhynchos). FEMS Microbiol Lett. 2007 May;270(2):227-36.

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