| General Information of DME (ID: DME0157) |
| DME Name |
Glutaminyl-tRNA synthetase (GLNRS), Homo sapiens
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| Synonyms |
Glutamine-specific glutamyl-transfer ribonucleate; Aminoacyl-tRNA amidotransferase; Glutamine--tRNA ligase; AA-tRNA amidotransferase; GlnRS; QARS; QARS1
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| Gene Name |
QARS1
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| UniProt ID |
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| Gene ID |
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| EC Number |
EC: 6.1.1.18 (Click to Show/Hide the Complete EC Tree)
Ligase
Carbon-oxygen ligase
Aminoacyl tRNA synthetase
EC: 6.1.1.18
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| Lineage |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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Interactome(loading-time for this interactome depdends on the speed of web connection)
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Interactions between Microbiome and DME (MICBIO)  Jump to Detailed Interactome Data  |
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Sequence |
MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA
SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE
QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK
LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT
PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL
RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ
RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV
KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV
QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG
VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET
KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES
LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL
HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV
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| Structure |
4R3Z
; 4YE6
; 4YE8
; 4YE9
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| Pathway |
Aminoacyl-tRNA biosynthesis (hsa00970 ) |
| Metabolic pathways (hsa01100 ) |
| Function |
This enzyme catalyzes the conversion of L-glutamine and tRNAGln to L-glutaminyl-tRNAGln.
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