| General Information of DME (ID: DME1164) |
| DME Name |
Xylose isomerase (xylA), Bifidobacterium adolescentis
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| Synonyms |
Xylose isomerase xylA; Isomerase xylA; Enzyme xylA; xylA; BAD_0422
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| Gene Name |
xylA
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| UniProt ID |
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| Gene ID |
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| EC Number |
EC: 5.3.1.5 (Click to Show/Hide the Complete EC Tree)
Isomerase
Intramolecular oxidoreductase
Aldose/ketose isomerase
EC: 5.3.1.5
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| Lineage |
Species: Bifidobacterium adolescentis (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
Species: Bifidobacterium adolescentis
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Interactome(loading-time for this interactome depdends on the speed of web connection)
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Interactions between Xenobiotics and DME (XEOTIC)  Jump to Detailed Interactome Data  |
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Tissue Distribution |
Primarily distributed in human gut.
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| Sequence |
MGLWDIDKIPYVGREKGPQEGLAFHYYDADKVVAGKKMKDWLRFGVAWWHTFDQQLVDPF
GTGTAQRPWYGKYSDPEDEALAKVDYAFEFFQKLGVEYFCFHDRDIAPEGDTLRETDKNL
DKVVDKIEENMKSTGIKLLWNTSSLFTNPRFVSGASTSPFADIYAYAGGQLKHSLEIAKR
LGAENYVFWGGREGYENLWNTQMKREQEHMAKFFHMCHDYAKEIGLDAQFLIEPKAKEPT
MFQYDFDAATAINFLRTYDLMDVFKLNLEGNHANLAGHTYQHEIRTAREAGVLGSLDANQ
GDKLIGWDMDEFPTDLYETSTVMWEVLAEGQIGPHGGLNFDAKPRRTSFTAEDLFRSHIA
GMDSFAAGLLVAAKMHEDKVIENLQAERYSSFDSGIGATVENGTASLASLEEYALDIPQS
KLIEATKSDHLESVKATINNYMIDALAEA
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| Pathway |
Fructose and mannose metabolism (bad00051 ) |
| Metabolic pathways (bad01100 ) |
| Pentose and glucuronate interconversions (bad00040 ) |
| Function |
This enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity. It binds the closed form of its sugar substrate (in the case of glucose, only the alpha anomer) and catalyses ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.
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