Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1274)
DME Name Unclear metabolic mechanism (DME-unclear), Klebsiella pneumoniae
Gene Name DME-unclear
Lineage    Species: Klebsiella pneumoniae     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Enterobacteriaceae
Genus: Klebsiella
Species: Klebsiella pneumoniae
Interactome
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       Interactions between Xenobiotics and DME (XEOTIC)                      
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      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human gut.
Full List of Drug(s) Metabolized by This DME
      Drugs Approved by FDA Click to Show/Hide the Full List of Drugs:          1 Drugs
Doxorubicin
 Drug Info Approved Breast cancer ICD11: 2C60 [1]
References
1 Transformation of the anticancer drug doxorubicin in the human gut microbiome. ACS Infect Dis. 2018 Jan 12;4(1):68-76.

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