Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1287)
DME Name Unclear metabolic mechanism (DME-unclear), Ralstonia solanacearum
Gene Name DME-unclear
Lineage    Species: Ralstonia solanacearum     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Burkholderiales
Family: Burkholderiaceae
Genus: Ralstonia
Species: Ralstonia solanacearum
Interactome
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       Interactions between Xenobiotics and DME (XEOTIC)                      
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      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human vagina.
Full List of Drug(s) Metabolized by This DME
      Drugs in Phase 2 Clinical Trial Click to Show/Hide the Full List of Drugs:          1 Drugs
ANW-43703
 Drug Info Phase 2/3 Anogenital warts ICD11: 1A95 [1], [2]
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
PS-3435
 Drug Info Preclinical Fatty liver disease ICD11: DB92 [2]
References
1 Vaginal microbiome in early pregnancy and subsequent risk of spontaneous preterm birth: a case-control study. BJOG. 2019 Feb;126(3):349-358.
2 Involvement of a PadR regulator PrhP on virulence of Ralstonia solanacearum by controlling detoxification of phenolic acids and type III secretion system. Mol Plant Pathol. 2019 Nov;20(11):1477-1490.

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