General Information of DME (ID: DME1728)
DME Name Beta-galactosidase (bgaB), Weissella paramesenteroides
Synonyms Beta-galactosidase/glucuronidase; Beta-galactosidase BgaBeta; Beta-Gal II; Beta-gal; EWR19_03520
Gene Name bgaB
UniProt ID
A0A4Q7IW92_WEIPA
Gene ID
42681659
EC Number    EC: 3.2.1.23     (Click to Show/Hide the Complete EC Tree)
Hydrolases
Glycosylase
O/S-glycosyl compound glycosidase
EC: 3.2.1.23
Lineage    Species: Weissella paramesenteroides     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Leuconostocaceae
Genus: Weissella
Species: Weissella paramesenteroides
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human gut.
Sequence
MTAKLEWLDDPTVFRVGKLPAHSDHKVYRSAAEVVQGESSLISSLDGTWRFHFAKTPAER
LINFEELNFNTENFDDIQVPGHIELQNFGQIQYINTLYPWEGKTYRRPPYALGADKTYPG
IFSEASDNTVGQYVKTFTLPDNFNSHDVHIQFDGVEEAMYVWLNGQFVGYSEDSFSRAEF
DLTPYLVNGENKLAVEVFKYSTAAFIEDQDMFRFSGIFRSVNLVAIPQVNVVDVHLKPVV
SDDLRSGNLAIALTLAGELSDTTAQIIVNNPRGEAVLERTVTAEQTIQINESIENIALWS
HKQPDLYELTVTIFDSDKQVIAVVPYAFGFRRLVKDANNHVTINGVPLHLNGVNRHEWSA
VGGRSVTLDEMKTDIEIFKENNINAVRTSHYPNQIPWYGMCDEAGIYMMAETNLESHGTW
QKMGAVEPSYNVPGSIPQWLDVVLDRAKSNFEQFKNHPSILFWSLGNESYTGDNLVAMDE
YFKSVDDSRLTHYEGIFQNRVDEDRMSDVESRMYASPADIQEYLSNNPKKPYLNCEYMHS
MGNSVGGFDEYVHLYDEFDTYLGGFIWDYIDQALYVTDEVTGKQVLRYGGDFDERHSDYE
FSGDGIVFANRQPKPAIQEVSYYYGRYDN
Pathway Galactose metabolism (wpa00052 )
Metabolic pathways (wpa01100 )
Other glycan degradation (wpa00511 )
Sphingolipid metabolism (wpa00600 )
Function This enzyme hydrolyzes alpha-L-arabinoside and beta-D-fucosides and beta-D-glucosides.
Full List of Drug(s) Metabolized by This DME
      Drugs in Phase 1 Clinical Trial Click to Show/Hide the Full List of Drugs:          1 Drugs
LS-69767
Drug Info Phase 1 Chronic myelogenous leukaemia ICD11: 2A20 [1]
References
1 In vitro fermentation of fructooligosaccharides with human gut bacteria. Food Funct. 2015 Mar;6(3):947-54.

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