Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1870)
DME Name Unclear metabolic mechanism (DME-unclear), Fusarium oxysporum
Gene Name DME-unclear
Lineage    Species: Fusarium oxysporum     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Fungi
Phylum: Ascomycota
Class: Sordariomycetes
Order: Hypocreales
Family: Nectriaceae
Genus: Fusarium
Species: Fusarium oxysporum
Subspecies: Fusarium oxysporum F-0001
Interactome
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       Interactions between Xenobiotics and DME (XEOTIC)                      
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      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human skin.
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          4 Drugs
Hydroxymanzamine A
 Drug Info Investigative Ovarian cancer ICD11: 2C73 [1]
Manzamine A
 Drug Info Investigative Pancreatic cancer ICD11: 2C10 [1]
Manzamine F
 Drug Info Investigative Ovarian cancer ICD11: 2C73 [1]
Ircinal A
 Drug Info Investigative Alzheimer disease ICD11: 8A20 [1]
References
1 Metabolism and resistance of Fusarium spp. to the manzamine alkaloids via a putative retro pictet-spengler reaction and utility of the rational design of antimalarial and antifungal agents. Mar Biotechnol (NY). 2014 Aug;16(4):412-22.

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