Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN036)
DME Name Permidine/putrescine ABC transporter substrate-binding protein (BleG1_1835), Bacillus pumilus
Gene Name BleG1_1835
UniProt ID
A0A060M1I7_9BACI
EC Number    EC: 3.1.1.1     (Click to Show/Hide the Complete EC Tree)
Hydrolases
Ester bond hydrolase
Carboxylic ester hydrolase
EC: 3.1.1.1
Lineage    Species: Bacillus pumilus     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Bacillaceae
Genus: Bacillus
Species: Bacillus pumilus
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Sequence
MKKSITVTLGMAAITALVGCGQSGSDPSEAPTDLVISTWGFAEDFFNEEVYAPFEEEHNV
NIVVDIGNNAERLNRIRQGTATIDVIYLSDYYAQQGIDEGLFANIDRSRIPAIEDLYDLA
QAPLGEEYGPAYTVGQFGIAYNPDEVESPITSWSDLWDEALANNITLPNITATTGPMFLD
AASIVAGEETFNEDAAFDQLNTLKGNVVKEYDRTSDFVNMFSQGEIVAGPFMEMYLKDLL
AAVPGTEFVTPSEGAYAVLNTVNVVEGSNNKELAEEFINWHLSKEVQEASAKAKIDSPVN
KLVELSSEEAEGITYGEDTINELKLLDMEFVNEQSAQWIDRWNREIAN
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
Agmatine
 Drug Info Investigative Discovery agent ICD: N.A. [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR003070 Spermidine N1-AcSpd Unclear - Unclear Agmatine [1]
MR003069 Spermine N-AcSpm Unclear - Unclear Agmatine [1]
References
1 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.

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