Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN238)
DME Name aldehyde dehydrogenase (ALDH), Bacteroides fragilis
Gene Name ALDH
Lineage    Species: Bacteroides fragilis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
Species: Bacteroides fragilis
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR004639 Ibuprofen Metabolite M7 Ibuprofen Metabolite M8 Unclear - Unclear Ibuprofen [1]
MR012996 Perillaldehyde (PCO) Perillic acid (PCOOH) Oxidation - Oxidation Perillyl alcohol [2]
MR012995 Perillyl alcohol Perillaldehyde (PCO) Oxidation - Oxidation Perillyl alcohol [2]
References
1 Genetic Characterization of the Ibuprofen-Degradative Pathway of Rhizorhabdus wittichii MPO218
2 Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat

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