Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN243)
DME Name Amidase (AMS), Homo sapiens
Gene Name AMS
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR005049 Flutamide Flutamide Metabolite M3 Unclear - Unclear Flutamide [1]
MR013003 TNP-470 TNP-470 Metabolite MIV Unclear - Unclear TNP-470 [2]
References
1 Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites
2 Pharmacokinetics and metabolism of O-(chloroacetyl-carbamoyl) fumagillol (TNP-470, AGM-1470) in rhesus monkeys

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