Details of Drug-Metabolizing Enzyme (DME)
| General Information of DME (ID: DMEN773) | |||||
|---|---|---|---|---|---|
| DME Name | long-chain 3-ketoacyl-CoA thiolas (LCKAT), Homo sapiens | ||||
| Gene Name | LCKAT | ||||
| Lineage | Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage) | ||||
| Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME | |||||
| Full List of Drug(s) Metabolized by This DME | |||||
|---|---|---|---|---|---|
| Drugs Approved by FDA | Click to Show/Hide the Full List of Drugs: 1 Drugs | ||||
Sodium phenylbutyrate |
Drug Info | Approved | Muscular atrophy | ICD11: 8B61 | [1] |
| Drugs in Phase 2 Clinical Trial | Click to Show/Hide the Full List of Drugs: 2 Drugs | ||||
Phenylbutyrate |
Drug Info | Phase 2 | Phenylketonuria | ICD11: 5C50 | [1] |
Phenylbutyrate |
Drug Info | Phase 2 | Phenylketonuria | ICD11: 5C50 | [2] |
| References | |||||
|---|---|---|---|---|---|
| 1 | Identification of enzymes involved in oxidation of phenylbutyrate | ||||
| 2 | New secondary metabolites of phenylbutyrate in humans and rats | ||||
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