Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN784)
DME Name mixed function oxidases (MFO), Homo sapiens
Gene Name MFO
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Drug(s) Metabolized by This DME
      Drugs Approved by FDA Click to Show/Hide the Full List of Drugs:          1 Drugs
Altretamine
 Drug Info Approved Ovarian cancer ICD11: 2C73 [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR008962 N2N2-DMM MMM Unclear - Unclear Altretamine [1]
MR008961 N2N2N4-TriMM N2N2-DMM Unclear - Unclear Altretamine [1]
MR008960 N2N2N4N4-TMM N2N2N4-TriMM Unclear - Unclear Altretamine [1]
MR008955 N2N2N4N6-TMM N2N4N6-TriMM Unclear - Unclear Altretamine [1]
MR008957 N2N4-DMM MMM Unclear - Unclear Altretamine [1]
MR008956 N2N4N6-TriMM N2N4-DMM Unclear - Unclear Altretamine [1]
MR008954 PMM N2N2N4N6-TMM Unclear - Unclear Altretamine [1]
⏷ Show the Full List of 7 MR(s)
References
1 Clinical pharmacokinetics of altretamine

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