Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN790)
DME Name perillyl-CoA hydratase (BN940_14026), Castellaniella defragrans 65Phen
Gene Name BN940_14026
UniProt ID
W8X9Q8_CASDE
EC Number    EC: 1.1.1.35     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
CH-OH donor oxidoreductase
NAD/NADP oxidoreductase
EC: 1.1.1.35
Lineage    Species: Castellaniella defragrans 65Phen     (Click to Show/Hide the Complete Species Lineage)
Kingdom: .
Phylum: .
Class: .
Order: .
Family: .
Genus: .
Species: Castellaniella defragrans 65Phen
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Sequence
MTDQNIKTALGEDGVLLARIDMPGRSMNVFSLEMMDSLERLLDRVESDERIVAVVLASGK
DSFLVGADLSMIRMFTERARTDTHDQLVDLCGRLGRLFRRLERSAKPFVAAVDGLALGGG
LELCLASHARVLSDRKRVALGLPEIKLGLLPGAGGTQRLPRLIGVRRGLDMLLRGEPVRA
GAALACGLADEIVPADQLIDRARAKALGMDGGKPRHLTGAFYDTDDEEIRPGDAGAHERI
ARALALDDALLERYPAYRAIMDCVIQGWAMPIDLALDNEMDVFVRLIQDPVAGNMVRALF
LDRQRSLKSLDIPLEVPPEAGGVPVGTCGPDEAGLAAGCAAGVWAAPRGPYGQAVEILWD
GDPQARVAALIAARSLRPDAVLVTPGRDLVLAALARAAQAAQARGLPPEYGVALRAQEAA
EAGRVTDEALLDSAAVVAGIMPAWTGGPFAFLQRVGRAECERRAEAAGLSAGDRPRAAAD
CP
Full List of Drug(s) Metabolized by This DME
      Discontinued/withdrawn Drugs Click to Show/Hide the Full List of Drugs:          1 Drugs
Perillyl alcohol
 Drug Info Discontinued in Phase 2 Solid tumour/cancer ICD11: 2A00-2F9Z [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR012998 Perillyl-CoA 2-hydroxy-4-isopropenyl-cyclohexane-1-carboxyl-CoA Unclear - Unclear Perillyl alcohol [1]
References
1 The oxygen-independent metabolism of cyclic monoterpenes in Castellaniella defragrans 65Phen

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