Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN875)
DME Name	beta-lactamase TEM-1 (bla TEM-1), Bacteroides fragilis
Gene Name	bla TEM-1
Lineage	Species: Bacteroides fragilis (Click to Show/Hide the Complete Species Lineage) Kingdom: Bacteria Phylum: Bacteroidetes Class: Bacteroidia Order: Bacteroidales Family: Bacteroidaceae Genus: Bacteroides Species: Bacteroides fragilis
Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME

Full List of Drug(s) Metabolized by This DME
Drugs Approved by FDA			Click to Show/Hide the Full List of Drugs: 1 Drugs
Penicillin	Drug Info	Approved	Bacterial infection	ICD11: 1A00-1C4Z	[1], [2]

References
1	Mass spectral kinetic study of acylation and deacylation during the hydrolysis of penicillins and cefotaxime by beta-lactamase TEM-1 and the G238S mutant
2	N-aryl 3-halogenated azetidin-2-ones and benzocarbacephems, inhibitors of beta-lactamases

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