General Information of DME (ID: DMEN228)
DME Name N-Acetyl transferases (NATF), Bacteroides fragilis
Gene Name NATF
Lineage    Species: Bacteroides fragilis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
Species: Bacteroides fragilis
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Drug(s) Metabolized by This DME
      Drugs Approved by FDA Click to Show/Hide the Full List of Drugs:          1 Drugs
Ibrutinib
Drug Info Approved Mantle cell lymphoma ICD11: 2A85 [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR012951 ICYS Ibrutinib-mercapturic acid Unclear - Unclear Ibrutinib [1]
MR013630 T-2513 T-3921 Unclear - Unclear T-0128 [2]
References
1 Extrahepatic metabolism of ibrutinib
2 Clinical and pharmacologic study of the novel prodrug delimotecan (MEN 4901/T-0128) in patients with solid tumors

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