Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN275)
DME Name nicotinic acid mononucleotide adenylyltransferase (NMNAT), Homo sapiens
Gene Name NMNAT
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Drug(s) Metabolized by This DME
      Drugs in Phase 3 Clinical Trial Click to Show/Hide the Full List of Drugs:          1 Drugs
Favipiravir
 Drug Info Phase 3 Influenza virus infection ICD11: 1E30-1E32 [1]
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
Deamido-NAD
 Drug Info Investigative Discovery agent ICD: N.A. [2]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR005794 NaMN NaAD(Deamido-NAD) Unclear - Unclear Deamido-NAD [2]
References
1 Favipiravir and Its Structural Analogs: Antiviral Activity and Synthesis Methods
2 Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency. J Biol Chem. 2003 Mar 28;278(13):10914-21.

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