Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN325)
DME Name N-acetyltransferases (NATs), Homo sapiens
Gene Name NATs
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR006407 Hydrolyzed hydroxytriptolide Hydrolyzed hydroxytriptolide N-acetylcycteine Conjugation - Conjugation PG-490 [1]
MR006409 Hydrolyzed triptolide Hydrolyzed hydroxytriptolide N-acetylcycteine Conjugation - Conjugation PG-490 [1]
References
1 Preclinical pharmacokinetics of triptolide: a potential antitumor drug. Curr Drug Metab. 2019;20(2):147-154.

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