General Information of DME (ID: DMEN793)
DME Name carboxylesterase (CarbE), Homo sapiens
Gene Name CarbE
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Drug(s) Metabolized by This DME
      Discontinued/withdrawn Drugs Click to Show/Hide the Full List of Drugs:          1 Drugs
Clinprost
Drug Info Discontinued in Preregistration Asthma ICD11: CA23 [1]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR009466 Clinprost Isocarbacyclin Hydrolysis - Hydrolysis Clinprost [2], [3], [1]
References
1 Species differences in hydrolysis of isocarbacyclin methyl ester (TEI-9090) by blood esterases
2 Blood-brain-barrier transport of lipid microspheres containing clinprost, a prostaglandin I2 analogue
3 Binding affinities of isocarbacyclin methyl ester and its free acid to prostanoid receptors

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