Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN802)
DME Name monophosphate kinase (MPK), Homo sapiens
Gene Name MPK
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR009976 6-thioguanine monophosphate 6-thioguanine diphosphate Unclear - Unclear Mercaptopurine [1], [2]
References
1 Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
2 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity

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