| General Information of Drug Metabolite (DM) (ID: DM000132) |
| DM Name |
Small peptides
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Metalloprotease (MMP)
|
DMEN066
|
| Unclear - Unclear |
Exenatide
|
[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Exenatide |
DR0676
|
Approved |
Diabetes mellitus |
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| Plecanatide |
DR5378
|
Approved |
Chronic idiopathic constipation |
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| Setmelanotide |
DR5345
|
Approved |
Obesity |
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| References |
| 1 |
In vitro metabolic stability of exendin-4: pharmacokinetics and identification of cleavage products. PLoS One. 2015 Feb 27;10(2):e0116805.
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