Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM000134)
DM Name	Exendin-4(16C39)

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Aminopeptidase (AP)	DMEN069	Exenatide	Unclear - Unclear	Exenatide	[1]
Metalloprotease (MMP)	DMEN066	Exenatide	Unclear - Unclear	Exenatide	[1]
Serineprotease (SP)	DMEN067	Exenatide	Unclear - Unclear	Exenatide	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Exenatide		DR0676	Approved		Diabetes mellitus

References
1	In vitro metabolic stability of exendin-4: pharmacokinetics and identification of cleavage products. PLoS One. 2015 Feb 27;10(2):e0116805.

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