| General Information of Drug Metabolite (DM) (ID: DM000425) |
| DM Name |
15-demethyl tacrolimus
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Deamination |
Tacrolimus
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Tacrolimus |
DR1524
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Approved |
Ulcerative colitis |
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| References |
| 1 |
Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics Drug Metab Pharmacokinet. 2007 Oct;22(5):328-35. doi: 10.2133/dmpk.22.328.
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