| General Information of Drug Metabolite (DM) (ID: DM000441) |
| DM Name |
Tamsulosin M-4 metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Demethylation |
Tamsulosin
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Tamsulosin |
DR1530
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Approved |
Prostatic hyperplasia |
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| References |
| 1 |
Pharmacokinetics and plasma protein binding of tamsulosin hydrochloride in rats, dogs, and humans Drug Metab Dispos. 1998 Mar;26(3):240-5.
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| 2 |
Absorption, metabolism and excretion of tamsulosin hydrochloride in man Xenobiotica. 1996 Jun;26(6):637-45. doi: 10.3109/00498259609046739.
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