General Information of Drug Metabolite (DM) (ID: DM000441)
DM Name
Tamsulosin M-4 metabolite
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2D6 (CYP2D6) DME0009 Oxidation - Demethylation Tamsulosin [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Tamsulosin DR1530 Approved Prostatic hyperplasia
References
1 Pharmacokinetics and plasma protein binding of tamsulosin hydrochloride in rats, dogs, and humans Drug Metab Dispos. 1998 Mar;26(3):240-5.
2 Absorption, metabolism and excretion of tamsulosin hydrochloride in man Xenobiotica. 1996 Jun;26(6):637-45. doi: 10.3109/00498259609046739.

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