| General Information of Drug Metabolite (DM) (ID: DM000445) |
| DM Name |
Tamsulosin AM-1 metabolite
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Oxidation - Oxidative Deamination |
Tamsulosin
|
[1] , [2] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Tamsulosin |
DR1530
|
Approved |
Prostatic hyperplasia |
|
|
| References |
| 1 |
Pharmacokinetics and plasma protein binding of tamsulosin hydrochloride in rats, dogs, and humans Drug Metab Dispos. 1998 Mar;26(3):240-5.
|
| 2 |
Absorption, metabolism and excretion of tamsulosin hydrochloride in man Xenobiotica. 1996 Jun;26(6):637-45. doi: 10.3109/00498259609046739.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
