| General Information of Drug Metabolite (DM) (ID: DM000449) |
| DM Name |
hydroxy tapentado
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Hydroxylation |
Tapentadol
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Tapentadol |
DR1531
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Approved |
Neuropathic pain |
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| References |
| 1 |
Investigations into the drug-drug interaction potential of tapentadol in human liver microsomes and fresh human hepatocytes. Drug Metab Lett. 2008 Jan;2(1):67-75.
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