| General Information of Drug Metabolite (DM) (ID: DM000568) |
| DM Name |
Efavirenz metabolite M5
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Sulfotransferase (SULT)
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DMEN061
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| Conjugation - Conjugation |
Efavirenz
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[1] |
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UDP-glucuronyltransferase (UGT)
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DMEN064
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| Conjugation - Conjugation |
Efavirenz
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Efavirenz |
DR0560
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Approved |
Human immunodeficiency virus infection |
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| References |
| 1 |
Clinical pharmacokinetics and drug-drug interactions of Elbasvir/Grazoprevir. Eur J Drug Metab Pharmacokinet. 2018 Oct;43(5):509-531.
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