| General Information of Drug Metabolite (DM) (ID: DM001078) |
| DM Name |
Meclizine metabolite M1
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Hydroxylation |
Meclizine
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Meclizine |
DR1006
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Approved |
Functional nausea/vomiting |
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| References |
| 1 |
Meclizine metabolism and pharmacokinetics: formulation on its absorption. J Clin Pharmacol. 2012 Sep;52(9):1343-9.
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