Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM001082)
DM Name	2beta-,6beta-dihydroxymedroxyprogesterone acetate

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 3A4 (CYP3A4)	DME0001	6beta-hydroxymedroxyprogesterone Acetate	Oxidation - Hydroxylation	Medroxyprogesterone acetate	[1]
Cytochrome P450 3A4 (CYP3A4)	DME0001	2beta-hydroxymedroxyprogesterone acetate	Oxidation - Hydroxylation	Medroxyprogesterone acetate	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Medroxyprogesterone acetate		DR1012	Approved		Breast cancer

References
1	Metabolic profiling and cytochrome P450 reaction phenotyping of medroxyprogesterone acetate. Drug Metab Dispos. 2008 Nov;36(11):2292-8.

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