General Information of Drug Metabolite (DM) (ID: DM001097)
DM Name
Megestrol acetate metabolite M2
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Oxidation Megestrol acetate [1]
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
UDP-glucuronosyltransferase 2B17 (UGT2B17) DME0066 Conjugation - Glucuronidation Megestrol acetate [1]
Full List of Drug(s) That Produce This DM By Metabolism
Megestrol acetate DR1017 Approved Breast cancer
References
1 Metabolism of megestrol acetate in vitro and the role of oxidative metabolites. Xenobiotica. 2018 Oct;48(10):973-983.

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