| General Information of Drug Metabolite (DM) (ID: DM001097) |
| DM Name |
Megestrol acetate metabolite M2
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidation |
Megestrol acetate
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 2B17 (UGT2B17)
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DME0066
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| Conjugation - Glucuronidation |
Megestrol acetate
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Megestrol acetate |
DR1017
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Approved |
Breast cancer |
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| References |
| 1 |
Metabolism of megestrol acetate in vitro and the role of oxidative metabolites. Xenobiotica. 2018 Oct;48(10):973-983.
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