General Information of Drug Metabolite (DM) (ID: DM001287)
DM Name
Glucuronide conjugates of secnidazole
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronyltransferase (UGT) DMEN064 Conjugation - Conjugation Secnidazole [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Secnidazole DR2431 Approved Amebiasis
References
1 In vitro metabolic profile and drug-drug interaction assessment of secnidazole, a high-dose 5-nitroimidazole antibiotic for the treatment of bacterial vaginosis Pharmacol Res Perspect. 2020 Aug;8(4):e00634. doi: 10.1002/prp2.634.
2 Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis Drugs. 1996 Apr;51(4):621-38. doi: 10.2165/00003495-199651040-00007.

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