| General Information of Drug Metabolite (DM) (ID: DM001287) |
| DM Name |
Glucuronide conjugates of secnidazole
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronyltransferase (UGT)
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DMEN064
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| Conjugation - Conjugation |
Secnidazole
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Secnidazole |
DR2431
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Approved |
Amebiasis |
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| References |
| 1 |
In vitro metabolic profile and drug-drug interaction assessment of secnidazole, a high-dose 5-nitroimidazole antibiotic for the treatment of bacterial vaginosis Pharmacol Res Perspect. 2020 Aug;8(4):e00634. doi: 10.1002/prp2.634.
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| 2 |
Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis Drugs. 1996 Apr;51(4):621-38. doi: 10.2165/00003495-199651040-00007.
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