| General Information of Drug Metabolite (DM) (ID: DM002453) |
| DM Name |
Fulvestrant glucuronide metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronyltransferase (UGT)
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DMEN064
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| Conjugation - Glucuronidation |
Fulvestrant
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Fulvestrant |
DR0756
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Approved |
Breast cancer |
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| References |
| 1 |
Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue. Mol Pharmacol. 2006 Mar;69(3):908-20.
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