| General Information of Drug Metabolite (DM) (ID: DM002731) |
| DM Name |
DP-2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Plasma esterase (PE)
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DMEN068
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| Hydrolysis - Hydrolysis |
Otilonium
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Otilonium |
DR1209
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Phase 4 |
Irritable bowel syndrome |
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| References |
| 1 |
Determination of the unstable drug otilonium bromide in human plasma by LC-ESI-MS and its application to a pharmacokinetic study J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Oct 15;878(28):2896-900. doi: 10.1016/j.jchromb.2010.08.003.
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