| General Information of Drug Metabolite (DM) (ID: DM002952) |
| DM Name |
Des-nitroso derivative, Pretomanid
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Deazaflavin-dependent nitroreductase (SAML1065)
|
DMEN058
|
| Reduction - Reduction |
Pretomanid
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Pretomanid |
DR1338
|
Approved |
Pulmonary tuberculosis |
|
|
| References |
| 1 |
Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid ACS Med Chem Lett. 2017 Nov 13;8(12):1275-1280. doi: 10.1021/acsmedchemlett.7b00356.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
